List of works - Peter M. Tessier

Advances in Antibody Design

scientific article (publication date: 2015)

Aggregation-resistant domain antibodies engineered with charged mutations near the edges of the complementarity-determining regions

scientific article published on 27 July 2012

An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies

scientific article published on January 2015

Aromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathways

scientific article published on 23 November 2010

Biophysical and Sequence-Based Methods for Identifying Monovalent and Bivalent Antibodies with High Colloidal Stability

scientific article published on 20 November 2017

Biospecific protein immobilization for rapid analysis of weak protein interactions using self-interaction nanoparticle spectroscopy

scientific article

Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies

scientific article

Comparison of Human and Bovine Insulin Amyloidogenesis under Uniform Shear.

scientific article

Correlation of diafiltration sieving behavior of lysozyme-BSA mixtures with osmotic second virial cross-coefficients

scientific article published in August 2004

Deamidation Can Compromise Antibody Colloidal Stability and Enhance Aggregation in a pH-Dependent Manner

scientific article published on 16 April 2019

Design and Optimization of Anti-amyloid Domain Antibodies Specific for β-Amyloid and Islet Amyloid Polypeptide

scientific article published on 24 November 2015

Directed evolution methods for overcoming trade-offs between protein activity and stability

scientific article published on 09 October 2019

Directed evolution of conformation-specific antibodies for sensitive detection of polypeptide aggregates in therapeutic drug formulations

scientific article published on 23 October 2020

Discovery of highly soluble antibodies prior to purification using affinity-capture self-interaction nanoparticle spectroscopy

scientific article published on 12 September 2015

Efficient affinity maturation of antibody variable domains requires co-selection of compensatory mutations to maintain thermodynamic stability

scientific article published on 28 March 2017

Emerging methods for identifying monoclonal antibodies with low propensity to self-associate during the early discovery process

scientific article

Engineered Autonomous Human Variable Domains

scientific article

Engineering Aggregation-Resistant Antibodies ⬇️

scientific article published on March 29, 2012

Facile Preparation of Stable Antibody-Gold Conjugates and Application to Affinity-Capture Self-Interaction Nanoparticle Spectroscopy

scientific article

High-throughput analysis of concentration-dependent antibody self-association.

scientific article published on October 2011

High-throughput assay for measuring monoclonal antibody self-association and aggregation in serum

scientific article published on 6 March 2015

High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy

scientific article published on 6 December 2013

Improving monoclonal antibody selection and engineering using measurements of colloidal protein interactions

scientific article

Intrahippocampal administration of a domain antibody that binds aggregated amyloid-β reverses cognitive deficits produced by diet-induced obesity

scientific article

Lifting the veil on amyloid drug design

scientific article published on 16 July 2013

Measurements of Monoclonal Antibody Self-Association Are Correlated with Complex Biophysical Properties

scientific article published on 5 April 2016

Mechanisms of transthyretin inhibition of β-amyloid aggregation in vitro

scientific article published on December 2013

Modulation of curli assembly and pellicle biofilm formation by chemical and protein chaperones

scientific article

Mutational analysis of domain antibodies reveals aggregation hotspots within and near the complementarity determining regions

scientific article published on 5 July 2011

Optimal charged mutations in the complementarity-determining regions that prevent domain antibody aggregation are dependent on the antibody scaffold

scientific article

Plasmonic measurements of monoclonal antibody self-association using self-interaction nanoparticle spectroscopy

scientific article

Polyphenolic disaccharides endow proteins with unusual resistance to aggregation

scientific article published on 02 March 2012

Polyphenolic glycosides and aglycones utilize opposing pathways to selectively remodel and inactivate toxic oligomers of amyloid β.

scientific article published on 10 June 2011

Predictive crystallization of ribonuclease A via rapid screening of osmotic second virial coefficients

scientific article

Prion recognition elements govern nucleation, strain specificity and species barriers

scientific article

Rapid analysis of antibody self-association in complex mixtures using immunogold conjugates

scientific article published on 8 March 2013

Rational design of potent domain antibody inhibitors of amyloid fibril assembly

scientific article

Removal versus fragmentation of amyloid-forming precursors via membrane filtration

scientific article published on 06 November 2011

Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers

scientific article published on 28 May 2010

Self-interaction chromatography: a novel screening method for rational protein crystallization

article

Self-interaction nanoparticle spectroscopy: a nanoparticle-based protein interaction assay

scientific article published on 14 February 2008

Sensitive detection of glucagon aggregation using amyloid fibril-specific antibodies

scientific article published on 08 May 2019

Site-specific structural analysis of a yeast prion strain with species-specific seeding activity.

scientific article

Solution pH that minimizes self-association of three monoclonal antibodies is strongly dependent on ionic strength

scientific article published on 17 February 2012

Structure-based design of conformation- and sequence-specific antibodies against amyloid β.

scientific article published on 14 December 2011

Toward in silico CMC: An industrial collaborative approach to model-based process development

scientific article published on 29 July 2020

Unraveling infectious structures, strain variants and species barriers for the yeast prion [PSI+].

scientific article published in June 2009

List of works by Peter M. Tessier

Advances in Antibody Design

Aggregation-resistant domain antibodies engineered with charged mutations near the edges of the complementarity-determining regions

An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies

Aromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathways

Biophysical and Sequence-Based Methods for Identifying Monovalent and Bivalent Antibodies with High Colloidal Stability

Biospecific protein immobilization for rapid analysis of weak protein interactions using self-interaction nanoparticle spectroscopy

Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies

Comparison of Human and Bovine Insulin Amyloidogenesis under Uniform Shear.

Correlation of diafiltration sieving behavior of lysozyme-BSA mixtures with osmotic second virial cross-coefficients

Deamidation Can Compromise Antibody Colloidal Stability and Enhance Aggregation in a pH-Dependent Manner

Design and Optimization of Anti-amyloid Domain Antibodies Specific for β-Amyloid and Islet Amyloid Polypeptide

Directed evolution methods for overcoming trade-offs between protein activity and stability

Directed evolution of conformation-specific antibodies for sensitive detection of polypeptide aggregates in therapeutic drug formulations

Discovery of highly soluble antibodies prior to purification using affinity-capture self-interaction nanoparticle spectroscopy

Efficient affinity maturation of antibody variable domains requires co-selection of compensatory mutations to maintain thermodynamic stability

Emerging methods for identifying monoclonal antibodies with low propensity to self-associate during the early discovery process

Engineered Autonomous Human Variable Domains

Engineering Aggregation-Resistant Antibodies ⬇️

Facile Preparation of Stable Antibody-Gold Conjugates and Application to Affinity-Capture Self-Interaction Nanoparticle Spectroscopy

High-throughput analysis of concentration-dependent antibody self-association.

High-throughput assay for measuring monoclonal antibody self-association and aggregation in serum

High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy

Improving monoclonal antibody selection and engineering using measurements of colloidal protein interactions

Intrahippocampal administration of a domain antibody that binds aggregated amyloid-β reverses cognitive deficits produced by diet-induced obesity

Lifting the veil on amyloid drug design

Measurements of Monoclonal Antibody Self-Association Are Correlated with Complex Biophysical Properties

Mechanisms of transthyretin inhibition of β-amyloid aggregation in vitro

Modulation of curli assembly and pellicle biofilm formation by chemical and protein chaperones

Mutational analysis of domain antibodies reveals aggregation hotspots within and near the complementarity determining regions

Optimal charged mutations in the complementarity-determining regions that prevent domain antibody aggregation are dependent on the antibody scaffold

Plasmonic measurements of monoclonal antibody self-association using self-interaction nanoparticle spectroscopy

Polyphenolic disaccharides endow proteins with unusual resistance to aggregation

Polyphenolic glycosides and aglycones utilize opposing pathways to selectively remodel and inactivate toxic oligomers of amyloid β.

Predictive crystallization of ribonuclease A via rapid screening of osmotic second virial coefficients

Prion recognition elements govern nucleation, strain specificity and species barriers

Rapid analysis of antibody self-association in complex mixtures using immunogold conjugates

Rational design of potent domain antibody inhibitors of amyloid fibril assembly

Removal versus fragmentation of amyloid-forming precursors via membrane filtration

Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers

Self-interaction chromatography: a novel screening method for rational protein crystallization

Self-interaction nanoparticle spectroscopy: a nanoparticle-based protein interaction assay

Sensitive detection of glucagon aggregation using amyloid fibril-specific antibodies

Site-specific structural analysis of a yeast prion strain with species-specific seeding activity.

Solution pH that minimizes self-association of three monoclonal antibodies is strongly dependent on ionic strength

Structure-based design of conformation- and sequence-specific antibodies against amyloid β.

Toward in silico CMC: An industrial collaborative approach to model-based process development

Unraveling infectious structures, strain variants and species barriers for the yeast prion [PSI+].