List of works - Francesco Moccia

A functional transient receptor potential vanilloid 4 (TRPV4) channel is expressed in human endothelial progenitor cells.

scientific article published in January 2015

A new path to platelet production through matrix sensing.

scientific article published on 14 April 2017

A novel Ca²⁺-mediated cross-talk between endoplasmic reticulum and acidic organelles: implications for NAADP-dependent Ca²⁺ signalling

scientific article published on 21 January 2015

Acetylcholine induces intracellular Ca2+ oscillations and nitric oxide release in mouse brain endothelial cells

scientific article published on 12 June 2017

Angiogenesis and Vasculogenesis in Health and Disease

scientific article published on 10 June 2015

Anti-Inflammatory Properties of Bellevalia saviczii Root Extract and Its Isolated Homoisoflavonoid (Dracol) Are Mediated by Modification on Calcium Signaling

scientific article published on 17 September 2019

Arachidonic Acid Evokes an Increase in Intracellular Ca2+ Concentration and Nitric Oxide Production in Endothelial Cells from Human Brain Microcirculation

scientific article published on 09 July 2019

Automated Intracellular Calcium Profiles Extraction from Endothelial Cells Using Digital Fluorescence Images

scientific article published on 02 November 2018

Basal nonselective cation permeability in rat cardiac microvascular endothelial cells

scientific article

Breast and renal cancer-Derived endothelial colony forming cells share a common gene signature.

scientific article

Ca(2+) Signalling in Endothelial Progenitor Cells: Friend or Foe?

scientific article published on 06 August 2015

Ca2+ signaling in injured in situ endothelium of rat aorta

scientific article

Ca2+ signalling and membrane current activated by cADPr in starfish oocytes.

scientific article published on 16 May 2003

Ca2+ signalling in endothelial progenitor cells: a novel means to improve cell-based therapy and impair tumour vascularisation

scientific article published on 01 January 2014

Ca2+ uptake by the endoplasmic reticulum Ca2+-ATPase in rat microvascular endothelial cells.

scientific article published on May 2002

Calcium and fertilization: the beginning of life.

scientific article published in August 2004

Calcium as a Key Player in Arrhythmogenic Cardiomyopathy: Adhesion Disorder or Intracellular Alteration?

scientific article published on 16 August 2019

Canonical transient receptor potential 3 channel triggers vascular endothelial growth factor-induced intracellular Ca2+ oscillations in endothelial progenitor cells isolated from umbilical cord blood

scientific article published on 25 June 2013

Cardiac microvascular endothelial cells express a functional Ca+ -sensing receptor.

scientific article published on 24 June 2008

Ca²⁺-dependent nitric oxide release in the injured endothelium of excised rat aorta: a promising mechanism applying in vascular prosthetic devices in aging patients.

scientific article

Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells

scientific article published in May 2002

Characterization of novel cytoplasmic PARP in the brain of Octopus vulgaris

scientific article

Constitutive Store-Operated Ca(2+) Entry Leads to Enhanced Nitric Oxide Production and Proliferation in Infantile Hemangioma-Derived Endothelial Colony-Forming Cells

scientific article published on 9 December 2015

Definition, incidence and etiology: what's new in the 21st century?

scientific article published on September 2013

Differential clinical effects of different mutation subtypes in CALR-mutant myeloproliferative neoplasms.

scientific article published on 9 October 2015

Disrupted Calcium Signaling in Animal Models of Human Spinocerebellar Ataxia (SCA)

scientific article published on 27 December 2019

Dysregulation of VEGF-induced proangiogenic Ca2+ oscillations in primary myelofibrosis-derived endothelial colony-forming cells

scientific article published on 19 October 2015

Endolysosomal Ca Signalling and Cancer Hallmarks: Two-Pore Channels on the Move, TRPML1 Lags Behind!

scientific article published on 27 December 2018

Endoplasmic Reticulum Ca(2+) Handling and Apoptotic Resistance in Tumor-Derived Endothelial Colony Forming Cells.

scientific article published on 24 February 2016

Endothelial Ca2+ Signaling and the Resistance to Anticancer Treatments: Partners in Crime

scientific article

Endothelial progenitor cells support tumour growth and metastatisation: implications for the resistance to anti-angiogenic therapy.

scientific article published on 02 August 2015

Endothelial remodelling and intracellular calcium machinery

scientific article published on May 2014

Enhanced expression of Stim, Orai, and TRPC transcripts and proteins in endothelial progenitor cells isolated from patients with primary myelofibrosis

scientific article

Epidermal growth factor induces intracellular Ca2+ oscillations in microvascular endothelial cells

scientific article

Expression and function of toll-like receptors in human circulating endothelial colony forming cells.

scientific article

Flow-activated Na(+)and K(+)Current in cardiac microvascular endothelial cells

scientific article published on 01 August 2000

GABA(A)- and AMPA-like receptors modulate the activity of an identified neuron within the central pattern generator of the pond snail Lymnaea stagnalis

scientific article published on 13 February 2009

Generation and usage of aequorin lentiviral vectors for Ca(2+) measurement in sub-cellular compartments of hard-to-transfect cells

scientific article published on 10 March 2016

Glutamate triggers intracellular Ca2+ oscillations and nitric oxide release by inducing NAADP- and InsP3 -dependent Ca2+ release in mouse brain endothelial cells

scientific article published on 19 November 2018

Granular Layer Neurons Control Cerebellar Neurovascular Coupling Through an NMDA Receptor/NO-Dependent System.

scientific article

Group 1 metabotropic glutamate receptors trigger glutamate-induced intracellular Ca2+ signals and nitric oxide release in human brain microvascular endothelial cells

scientific article published on 31 August 2019

Hiatal hernia recurrence: surgical complication or disease? Electron microscope findings of the diaphragmatic pillars

scientific article

Histamine induces intracellular Ca2+ oscillations and nitric oxide release in endothelial cells from brain microvascular circulation

scientific article published on 16 July 2019

Honey-Mediated Wound Healing: H₂O₂ Entry through AQP3 Determines Extracellular Ca Influx ⬇️

scientific article published on 11 February 2019

How to utilize Ca²⁺ signals to rejuvenate the repairative phenotype of senescent endothelial progenitor cells in elderly patients affected by cardiovascular diseases: a useful therapeutic support of surgical approach?

scientific article

Hydrogen Sulfide-Evoked Intracellular Ca2+ Signals in Primary Cultures of Metastatic Colorectal Cancer Cells

scientific article published on 11 November 2020

Hydrogen sulfide and endothelial dysfunction: relationship with nitric oxide.

scientific article published on January 2014

Hydrogen sulfide as a regulator of calcium channels ⬇️

scientific article published on July 26, 2012

Hydrogen sulfide promotes calcium signals and migration in tumor-derived endothelial cells

scientific article published on 17 August 2011

Hydrogen sulfide regulates intracellular Ca2+ concentration in endothelial cells from excised rat aorta.

scientific article published in September 2011

Hydrogen sulphide triggers VEGF-induced intracellular Ca²⁺ signals in human endothelial cells but not in their immature progenitors.

scientific article published on 27 July 2014

Intracellular Ca²⁺ Signals to Reconstruct A Broken Heart: Still A Theoretical Approach?

scientific article

Is the advanced age a contraindication to GERD laparoscopic surgery? Results of a long term follow-up

scientific article published on 8 October 2013

Laparoscopic hiatal hernia repair. Is the mesh hiatoplasty justified?

scientific article published in January 2014

Latrunculin A depolarizes starfish oocytes

scientific article published on 5 September 2007

Liposomes as a Putative Tool to Investigate NAADP Signaling in Vasculogenesis

scientific article

Lost in phototransduction: a few facts and hypotheses on cephalopod photoresponse

scientific article published on June 2009

Lung Beractant Increases Free Cytosolic Levels of Ca2+ in Human Lung Fibroblasts

scientific article published on 31 July 2015

May the remodeling of the Ca²⁺ toolkit in endothelial progenitor cells derived from cancer patients suggest alternative targets for anti-angiogenic treatment?

scientific article

Muscarinic M5 receptors trigger acetylcholine-induced Ca2+ signals and nitric oxide release in human brain microvascular endothelial cells

scientific article published on 07 September 2018

NAADP activates a Ca2+ current that is dependent on F-actin cytoskeleton

scientific article

NAADP and InsP3 play distinct roles at fertilization in starfish oocytes

scientific article published on 20 March 2006

NAADP triggers the fertilization potential in starfish oocytes

scientific article published in December 2004

Na+-Ca2+ exchanger contributes to Ca2+ extrusion in ATP-stimulated endothelium of intact rat aorta

scientific article published on 29 March 2010

Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures

article

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Induces Intracellular Ca2+ Release through the Two-Pore Channel TPC1 in Metastatic Colorectal Cancer Cells

scientific article published on 15 April 2019

Nicotinic acid adenine dinucleotide phosphate activates two-pore channel TPC1 to mediate lysosomal Ca2+ release in endothelial colony-forming cells

scientific article published on 24 June 2020

Nitroso-Redox Balance and Modulation of Basal Myocardial Function: An Update from the Italian Society of Cardiovascular Research (SIRC).

scientific article published on 3 March 2015

Old and New Gasotransmitters in the Cardiovascular System: Focus on the Role of Nitric Oxide and Hydrogen Sulfide in Endothelial Cells and Cardiomyocytes ⬇️

scientific article published on September 1, 2011

Orai1 and transient receptor potential channels as novel molecular targets to impair tumor neovascularization in renal cell carcinoma and other malignancies

scientific article published on February 2014

Overall survival and quality of life in elderly patients treated for rectal cancer: results of a five year follow-up.

scientific article published on 16 September 2013

P2y1 and P2y2 receptor-operated Ca2+ signals in primary cultures of cardiac microvascular endothelial cells

scientific article published on 01 May 2001

Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in Thrombopoiesis

scientific article

Pharmacological characterization of NAADP-induced Ca2+ signals in starfish oocytes

scientific article published on 5 June 2006

Phosphatidylethanolamine Induces an Antifibrotic Phenotype in Normal Human Lung Fibroblasts and Ameliorates Bleomycin-Induced Lung Fibrosis in Mice

scientific article published on 14 September 2018

Polychlorinated biphenyls reduce the kinematics contractile properties of embryonic stem cells-derived cardiomyocytes by disrupting their intracellular Ca dynamics

scientific article published in Scientific Reports

Pre- and postsynaptic excitation and inhibition at octopus optic lobe photoreceptor terminals; implications for the function of the 'presynaptic bags'.

scientific article published in October 2007

Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting using the human amniotic fluid stem cell secretome

scientific article published on 04 April 2019

Retroperitoneal schwannoma unusually presenting as severe constipation.

scientific article published in January 2009

Sperm-attractant peptide influences the spermatozoa swimming behavior in internal fertilization in Octopus vulgaris.

scientific article

Stim and Orai proteins in neuronal Ca(2+) signaling and excitability

scientific article published on 24 April 2015

Store-dependent Ca(2+) entry in endothelial progenitor cells as a perspective tool to enhance cell-based therapy and adverse tumour vascularization.

scientific article published on January 2012

Store-operated Ca(2+) entry is expressed in human endothelial progenitor cells

scientific article published on 13 September 2010

Store-operated Ca2+ entry does not control proliferation in primary cultures of human metastatic renal cellular carcinoma.

scientific article

Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients

scientific article

Stromal Cell-Derived Factor-1α Promotes Endothelial Colony-Forming Cell Migration Through the Ca2+-Dependent Activation of the Extracellular Signal-Regulated Kinase 1/2 and Phosphoinositide 3-Kinase/AKT Pathways.

scientific article published on 9 November 2017

TRPC3-mediated Ca2+ signals as a promising strategy to boost therapeutic angiogenesis in failing hearts: The role of autologous endothelial colony forming cells

scientific article published on 17 August 2017

Targeting Calcium Signalling in Malignant Mesothelioma

scientific article published on 21 November 2019

Targeting Stim and Orai Proteins as an Alternative Approach in Anticancer Therapy.

scientific article

The M-phase-promoting factor modulates the sensitivity of the Ca2+ stores to inositol 1,4,5-trisphosphate via the actin cytoskeleton

scientific article published on 16 July 2003

The Plant Hormone Abscisic Acid Is a Prosurvival Factor in Human and Murine Megakaryocytes

scientific article published on 3 January 2017

The Role of Endothelial Ca2+ Signaling in Neurovascular Coupling: A View from the Lumen.

scientific article

The importance of calcium in the regulation of megakaryocyte function.

scientific article published on 24 January 2014

The mechanism of injury-induced intracellular calcium concentration oscillations in the endothelium of excised rat aorta

scientific article published on 11 October 2011

The role of endothelial colony forming cells in kidney cancer's pathogenesis, and in resistance to anti-VEGFR agents and mTOR inhibitors: A speculative review

scientific article published on 18 September 2018

Therapeutic Potential of Endothelial Colony-Forming Cells in Ischemic Disease: Strategies to Improve their Regenerative Efficacy

scientific article published on 07 October 2020

Type 2 Diabetes Alters Intracellular Ca2+ Handling in Native Endothelium of Excised Rat Aorta

scientific article published on 30 December 2019

Update on vascular endothelial Ca(2+) signalling: A tale of ion channels, pumps and transporters

scientific article

VEGF-induced intracellular Ca2+ oscillations are down-regulated and do not stimulate angiogenesis in breast cancer-derived endothelial colony forming cells

scientific article published on 14 August 2017

Vascular endothelial growth factor stimulates endothelial colony forming cells proliferation and tubulogenesis by inducing oscillations in intracellular Ca2+ concentration.

scientific article published in November 2011

List of works by Francesco Moccia

A functional transient receptor potential vanilloid 4 (TRPV4) channel is expressed in human endothelial progenitor cells.

A new path to platelet production through matrix sensing.

A novel Ca²⁺-mediated cross-talk between endoplasmic reticulum and acidic organelles: implications for NAADP-dependent Ca²⁺ signalling

Acetylcholine induces intracellular Ca2+ oscillations and nitric oxide release in mouse brain endothelial cells

Angiogenesis and Vasculogenesis in Health and Disease

Anti-Inflammatory Properties of Bellevalia saviczii Root Extract and Its Isolated Homoisoflavonoid (Dracol) Are Mediated by Modification on Calcium Signaling

Arachidonic Acid Evokes an Increase in Intracellular Ca2+ Concentration and Nitric Oxide Production in Endothelial Cells from Human Brain Microcirculation

Automated Intracellular Calcium Profiles Extraction from Endothelial Cells Using Digital Fluorescence Images

Basal nonselective cation permeability in rat cardiac microvascular endothelial cells

Breast and renal cancer-Derived endothelial colony forming cells share a common gene signature.

Ca(2+) Signalling in Endothelial Progenitor Cells: Friend or Foe?

Ca2+ signaling in injured in situ endothelium of rat aorta

Ca2+ signalling and membrane current activated by cADPr in starfish oocytes.

Ca2+ signalling in endothelial progenitor cells: a novel means to improve cell-based therapy and impair tumour vascularisation

Ca2+ uptake by the endoplasmic reticulum Ca2+-ATPase in rat microvascular endothelial cells.

Calcium and fertilization: the beginning of life.

Calcium as a Key Player in Arrhythmogenic Cardiomyopathy: Adhesion Disorder or Intracellular Alteration?

Canonical transient receptor potential 3 channel triggers vascular endothelial growth factor-induced intracellular Ca2+ oscillations in endothelial progenitor cells isolated from umbilical cord blood

Cardiac microvascular endothelial cells express a functional Ca+ -sensing receptor.

Ca²⁺-dependent nitric oxide release in the injured endothelium of excised rat aorta: a promising mechanism applying in vascular prosthetic devices in aging patients.

Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells

Characterization of novel cytoplasmic PARP in the brain of Octopus vulgaris

Constitutive Store-Operated Ca(2+) Entry Leads to Enhanced Nitric Oxide Production and Proliferation in Infantile Hemangioma-Derived Endothelial Colony-Forming Cells

Definition, incidence and etiology: what's new in the 21st century?

Differential clinical effects of different mutation subtypes in CALR-mutant myeloproliferative neoplasms.

Disrupted Calcium Signaling in Animal Models of Human Spinocerebellar Ataxia (SCA)

Dysregulation of VEGF-induced proangiogenic Ca2+ oscillations in primary myelofibrosis-derived endothelial colony-forming cells

Endolysosomal Ca Signalling and Cancer Hallmarks: Two-Pore Channels on the Move, TRPML1 Lags Behind!

Endoplasmic Reticulum Ca(2+) Handling and Apoptotic Resistance in Tumor-Derived Endothelial Colony Forming Cells.

Endothelial Ca2+ Signaling and the Resistance to Anticancer Treatments: Partners in Crime

Endothelial progenitor cells support tumour growth and metastatisation: implications for the resistance to anti-angiogenic therapy.

Endothelial remodelling and intracellular calcium machinery

Enhanced expression of Stim, Orai, and TRPC transcripts and proteins in endothelial progenitor cells isolated from patients with primary myelofibrosis

Epidermal growth factor induces intracellular Ca2+ oscillations in microvascular endothelial cells

Expression and function of toll-like receptors in human circulating endothelial colony forming cells.

Flow-activated Na(+)and K(+)Current in cardiac microvascular endothelial cells

GABA(A)- and AMPA-like receptors modulate the activity of an identified neuron within the central pattern generator of the pond snail Lymnaea stagnalis

Generation and usage of aequorin lentiviral vectors for Ca(2+) measurement in sub-cellular compartments of hard-to-transfect cells

Glutamate triggers intracellular Ca2+ oscillations and nitric oxide release by inducing NAADP- and InsP3 -dependent Ca2+ release in mouse brain endothelial cells

Granular Layer Neurons Control Cerebellar Neurovascular Coupling Through an NMDA Receptor/NO-Dependent System.

Group 1 metabotropic glutamate receptors trigger glutamate-induced intracellular Ca2+ signals and nitric oxide release in human brain microvascular endothelial cells

Hiatal hernia recurrence: surgical complication or disease? Electron microscope findings of the diaphragmatic pillars

Histamine induces intracellular Ca2+ oscillations and nitric oxide release in endothelial cells from brain microvascular circulation

Honey-Mediated Wound Healing: H₂O₂ Entry through AQP3 Determines Extracellular Ca Influx ⬇️

How to utilize Ca²⁺ signals to rejuvenate the repairative phenotype of senescent endothelial progenitor cells in elderly patients affected by cardiovascular diseases: a useful therapeutic support of surgical approach?

Hydrogen Sulfide-Evoked Intracellular Ca2+ Signals in Primary Cultures of Metastatic Colorectal Cancer Cells

Hydrogen sulfide and endothelial dysfunction: relationship with nitric oxide.

Hydrogen sulfide as a regulator of calcium channels ⬇️

Hydrogen sulfide promotes calcium signals and migration in tumor-derived endothelial cells

Hydrogen sulfide regulates intracellular Ca2+ concentration in endothelial cells from excised rat aorta.

Hydrogen sulphide triggers VEGF-induced intracellular Ca²⁺ signals in human endothelial cells but not in their immature progenitors.

Intracellular Ca²⁺ Signals to Reconstruct A Broken Heart: Still A Theoretical Approach?

Is the advanced age a contraindication to GERD laparoscopic surgery? Results of a long term follow-up

Laparoscopic hiatal hernia repair. Is the mesh hiatoplasty justified?

Latrunculin A depolarizes starfish oocytes

Liposomes as a Putative Tool to Investigate NAADP Signaling in Vasculogenesis

Lost in phototransduction: a few facts and hypotheses on cephalopod photoresponse

Lung Beractant Increases Free Cytosolic Levels of Ca2+ in Human Lung Fibroblasts

May the remodeling of the Ca²⁺ toolkit in endothelial progenitor cells derived from cancer patients suggest alternative targets for anti-angiogenic treatment?

Muscarinic M5 receptors trigger acetylcholine-induced Ca2+ signals and nitric oxide release in human brain microvascular endothelial cells

NAADP activates a Ca2+ current that is dependent on F-actin cytoskeleton

NAADP and InsP3 play distinct roles at fertilization in starfish oocytes

NAADP triggers the fertilization potential in starfish oocytes

Na+-Ca2+ exchanger contributes to Ca2+ extrusion in ATP-stimulated endothelium of intact rat aorta

Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Induces Intracellular Ca2+ Release through the Two-Pore Channel TPC1 in Metastatic Colorectal Cancer Cells

Nicotinic acid adenine dinucleotide phosphate activates two-pore channel TPC1 to mediate lysosomal Ca2+ release in endothelial colony-forming cells

Nitroso-Redox Balance and Modulation of Basal Myocardial Function: An Update from the Italian Society of Cardiovascular Research (SIRC).

Old and New Gasotransmitters in the Cardiovascular System: Focus on the Role of Nitric Oxide and Hydrogen Sulfide in Endothelial Cells and Cardiomyocytes ⬇️

Orai1 and transient receptor potential channels as novel molecular targets to impair tumor neovascularization in renal cell carcinoma and other malignancies

Overall survival and quality of life in elderly patients treated for rectal cancer: results of a five year follow-up.

P2y1 and P2y2 receptor-operated Ca2+ signals in primary cultures of cardiac microvascular endothelial cells

Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in Thrombopoiesis

Pharmacological characterization of NAADP-induced Ca2+ signals in starfish oocytes

Phosphatidylethanolamine Induces an Antifibrotic Phenotype in Normal Human Lung Fibroblasts and Ameliorates Bleomycin-Induced Lung Fibrosis in Mice

Polychlorinated biphenyls reduce the kinematics contractile properties of embryonic stem cells-derived cardiomyocytes by disrupting their intracellular Ca dynamics

Pre- and postsynaptic excitation and inhibition at octopus optic lobe photoreceptor terminals; implications for the function of the 'presynaptic bags'.

Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting using the human amniotic fluid stem cell secretome

Retroperitoneal schwannoma unusually presenting as severe constipation.