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List of works by Alexander Staruschenko

A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease

scientific article published on 23 May 2018

A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD.

scientific article published in October 2018

Acetylation stimulates the epithelial sodium channel by reducing its ubiquitination and degradation

scientific article published on 18 March 2015

Actin cytoskeleton disassembly affects conductive properties of stretch-activated cation channels in leukaemia cells

scientific article

Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure.

scientific article published on 12 September 2017

Aldosterone-dependent trans-activation and epigenetic derepression of ENaC: where is the balance?

scientific article

Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli

scientific article

Angiotensin II increases activity of the epithelial Na+ channel (ENaC) in distal nephron additively to aldosterone.

scientific article published on 15 November 2011

Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells

scientific article

Beneficial Effects of High Potassium: Contribution of Renal Basolateral K+ Channels

scientific article published on 30 April 2018

Binding and direct activation of the epithelial Na+ channel (ENaC) by phosphatidylinositides.

scientific article published on February 2007

Characterization of purinergic receptor expression in ARPKD cystic epithelia

scientific article published on 11 November 2018

Chronic cathepsin inhibition by E-64 in Dahl salt-sensitive rats.

scientific article published on September 2016

Cross-talk between insulin and IGF-1 receptors in the cortical collecting duct principal cells: implication for ENaC-mediated Na+ reabsorption.

scientific article

Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension.

scientific article published on 18 April 2013

Detection of endogenous substances with enzymatic microelectrode biosensors in the kidney

scientific article published on 17 April 2013

Direct activation of ENaC by angiotensin II: recent advances and new insights.

scientific article published on February 2013

Distal tubule basolateral potassium channels: cellular and molecular mechanisms of regulation

scientific article published on 01 September 2018

Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC)

scientific article

Endothelin receptor A and p66Shc regulate spontaneous Ca oscillations in smooth muscle cells controlling renal arterial spontaneous motion

scientific article published on 10 October 2018

Epidermal growth factor-mediated proliferation and sodium transport in normal and PKD epithelial cells ⬇️

scientific article published on October 16, 2010

Epidermal growth factors in the kidney and relationship to hypertension.

scientific article published on May 2013

Epithelial Na+ channel subunit stoichiometry

scientific article

Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.

scientific article

Essential role of Kir5.1 channels in renal salt handling and blood pressure control.

scientific article published on 21 September 2017

Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats

scientific article

Expression, localization, and functional properties of inwardly rectifying K+ channels in the kidney

scientific article published on 16 December 2019

Fluorescence resonance energy transfer analysis of subunit stoichiometry of the epithelial Na+ channel

scientific article published on 19 April 2004

Functional and therapeutic importance of purinergic signaling in polycystic kidney disease

scientific article published on 21 September 2016

Genetic mutation of Kcnj16 identifies Kir5.1-containing channels as key regulators of acute and chronic pH homeostasis

scientific article published on 03 January 2019

Giant multimodal heart motoneurons of Achatina fulica: a new cardioregulatory input in pulmonates.

scientific article published in August 2001

High salt diet and caffeine: food for thought.

scientific article published on October 2016

Hypertension and Diabetes Mellitus: The Chicken and Egg Problem.

scientific article

IR- Role of adaptor protein p66Shc in renal pathologies

scientific article

Identification of a functional phosphatidylinositol 3,4,5-trisphosphate binding site in the epithelial Na+ channel.

scientific article published on 9 September 2005

Impaired epithelial Na+ channel activity contributes to cystogenesis and development of autosomal recessive polycystic kidney disease in PCK rats

scientific article

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium.

scientific article

Inactivation of p66Shc Decreases Afferent Arteriolar KATP Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats

scientific article published on 21 August 2018

Increased ENaC activity during kidney preservation in Wisconsin solution

scientific article published on 29 April 2019

Inhibition of ENaC by endothelin-1

scientific article

Insulin and IGF-1 activate Kir4.1/5.1 channels in cortical collecting duct principal cells to control basolateral membrane voltage.

scientific article published on 2 December 2015

Intact cytoskeleton is required for small G protein dependent activation of the epithelial Na+ channel

scientific article

Intravital imaging of the kidney in a rat model of salt-sensitive hypertension

scientific article published on 12 April 2017

Intrinsic voltage dependence of the epithelial Na+ channel is masked by a conserved transmembrane domain tryptophan.

scientific article published on 20 July 2009

Involvement of ENaC in the development of salt-sensitive hypertension.

scientific article published on 21 December 2016

Ion channel regulation by Ras, Rho, and Rab small GTPases.

scientific article published on November 2007

Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats

scientific article

Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores

scientific article published on 04 January 2021

Magnesium permeation through mechanosensitive channels: single-current measurements.

scientific article published in August 2006

Mechanisms of non-steroid anti-inflammatory drugs action on ASICs expressed in hippocampal interneurons

scientific article published in July 2008

Mechanosensitive cation channels in human leukaemia cells: calcium permeation and blocking effect

scientific article

Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes

scientific article

Metabolic rewiring of the hypertensive kidney

scientific article published on 10 December 2019

Muscarinic M1 modulation of acid-sensing ion channels

scientific article

Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat.

scientific article

NOX4-dependent regulation of ENaC in hypertension and diabetic kidney disease

scientific article published on 16 August 2020

NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli

scientific article published on 5 April 2011

Nitric oxide production by glomerular podocytes

scientific article published on 8 November 2017

Novel role of Rac1/WAVE signaling mechanism in regulation of the epithelial Na+ channel.

scientific article published on 4 April 2011

Orally active epoxyeicosatrienoic acid analog attenuates kidney injury in hypertensive Dahl salt-sensitive rat.

scientific article published on 26 August 2013

PC and PKC: in vivo vs. in vitro

scientific article published on 26 December 2013

Peroxisome proliferator-activated receptor gamma antagonists decrease Na+ transport via the epithelial Na+ channel.

scientific article published on 14 September 2009

Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli.

scientific article published on 18 September 2013

Podocyte injury in diabetic nephropathy: implications of angiotensin II-dependent activation of TRPC channels

scientific article

Postprandial Effects on ENaC-Mediated Sodium Absorption

scientific article published on 12 March 2019

Postprandial effects on electrolyte homeostasis in the kidney

scientific article published on 30 September 2019

Progression of diabetic kidney disease in T2DN rats

scientific article published on 30 September 2019

Protease-activated receptors in kidney disease progression

scientific article

Protective role of Trpc6 knockout in the progression of diabetic kidney disease

scientific article published on 20 June 2018

Quantifying RhoA facilitated trafficking of the epithelial Na+ channel toward the plasma membrane with total internal reflection fluorescence-fluorescence recovery after photobleaching.

scientific article published on 21 March 2007

ROS production as a common mechanism of ENaC regulation by EGF, insulin, and IGF-1.

scientific article published on 7 November 2012

Rapid translocation and insertion of the epithelial Na+ channel in response to RhoA signaling.

scientific article published on 7 July 2006

Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling

scientific article

Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channel

scientific article published on 30 January 2005

Real-time electrochemical detection of ATP and H₂O₂ release in freshly isolated kidneys

scientific article published on 17 April 2013

Recording ion channels in isolated, split-opened tubules

scientific article published on January 2013

Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections

scientific article published on 19 June 2018

Regulation of ENaC expression at the cell surface by Rab11.

scientific article published on 14 October 2008

Regulation of Polycystin-1 Function by Calmodulin Binding

scientific article

Regulation of TRPC6 Channels by Non-Steroidal Anti-Inflammatory Drugs

scientific article

Regulation of epithelial Na+ channel activity by conserved serine/threonine switches within sorting signals

scientific article

Regulation of transport in the connecting tubule and cortical collecting duct

scientific article

Renal sodium transport in renin-deficient Dahl salt-sensitive rats.

scientific article published on 21 July 2016

Rho small GTPases activate the epithelial Na(+) channel

scientific article published on 23 September 2004

Role and mechanisms of regulation of the basolateral Kir 4.1/Kir 5.1K+ channels in the distal tubules

scientific article published on 30 April 2016

Role of Rho GDP dissociation inhibitor α in control of epithelial sodium channel (ENaC)-mediated sodium reabsorption

scientific article

Role of opioid signaling in kidney damage during the development of salt-induced hypertension

scientific article published on 12 October 2020

Role of the Scaffold Protein MIM in the Actin-Dependent Regulation of Epithelial Sodium Channels (ENaC)

scientific article published on 01 April 2018

Role of βPix in the Kidney

scientific article

Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC)

scientific article published on 08 February 2019

Sexual dimorphism in the progression of type 2 diabetic kidney disease in T2DN rats

scientific article published on 19 April 2021

Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli

scientific article

Single-channel analysis of TRPC channels in the podocytes of freshly isolated Glomeruli

scientific article

Subunit-dependent cadmium and nickel inhibition of acid-sensing ion channels.

scientific article

TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases

scientific article

The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling

scientific article

The actin cytoskeleton and small G protein RhoA are not involved in flow-dependent activation of ENaC.

scientific article

The function of SH2B3 (LNK) in the kidney

scientific article

The normal increase in insulin after a meal may be required to prevent postprandial renal sodium and volume losses

scientific article

To cleave or not to cleave: role of ADAM17 in cell proliferation in PKD.

scientific article

Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta

scientific article published on 10 June 2015

Two-photon imaging of endothelin-1-mediated intracellular Ca(2+) handling in smooth muscle cells of rat renal resistance arteries.

scientific article published on 9 December 2015

Use of Enzymatic Biosensors to Quantify Endogenous ATP or H2O2 in the Kidney

scientific article

Vibrodissociation method for isolation of defined nephron segments from human and rodent kidneys

scientific article published on 07 October 2019

Visualization and quantification of mitochondrial structure in the endothelium of intact arteries

scientific article published on 01 August 2019

p66Shc regulates renal vascular tone in hypertension-induced nephropathy.

scientific article

β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells.

scientific article published in June 2018

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