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List of works by Lei Chen

A Computational Method for Classifying Different Human Tissues with Quantitatively Tissue-Specific Expressed Genes

article

A Fast-FENICA method on resting state fMRI data ⬇️

scientific article published on May 29, 2012

A Shortest-Path-Based Method for the Analysis and Prediction of Fruit-Related Genes in Arabidopsis thaliana

scientific article

A computational method for the identification of new candidate carcinogenic and non-carcinogenic chemicals

scientific article published on 21 July 2015

A hybrid computational method for the discovery of novel reproduction-related genes

scientific article

A hybrid method for prediction and repositioning of drug Anatomical Therapeutic Chemical classes.

scientific article published on 04 February 2014

A novel approach for fMRI data analysis based on the combination of sparse approximation and affinity propagation clustering

scientific article

Alternative Polyadenylation Modification Patterns Reveal Essential Posttranscription Regulatory Mechanisms of Tumorigenesis in Multiple Tumor Types

scientific article published on 15 June 2020

An integrated method for the identification of novel genes related to oral cancer

scientific article

Analysis and prediction of drug-drug interaction by minimum redundancy maximum relevance and incremental feature selection.

scientific article published on 11 January 2016

Analysis of Expression Pattern of snoRNAs in Different Cancer Types with Machine Learning Algorithms ⬇️

scientific article published on 02 May 2019

Analysis of Gene Expression Profiles in the Human Brain Stem, Cerebellum and Cerebral Cortex

scientific article

Analysis of cancer-related lncRNAs using gene ontology and KEGG pathways.

scientific article published on 13 February 2017

Analysis of metabolic pathway using hybrid properties

scientific article published in January 2012

Analysis of the chemical toxicity effects using the enrichment of Gene Ontology terms and KEGG pathways

scientific article published on 18 May 2016

Analysis of tumor suppressor genes based on gene ontology and the KEGG pathway

scientific article

Application of systems biology and bioinformatics methods in biochemistry and biomedicine

scientific article published on 31 December 2013

Application of systems biology and bioinformatics methods in biochemistry and biomedicine 2014.

scientific article published on 19 April 2015

Classification and analysis of regulatory pathways using graph property, biochemical and physicochemical property, and functional property

scientific article

Classification of Widely and Rarely Expressed Genes with Recurrent Neural Network

article

Classifying ten types of major cancers based on reverse phase protein array profiles

scientific article published on 30 March 2015

Computational analysis of HIV-1 resistance based on gene expression profiles and the virus-host interaction network

scientific article

Computationally identifying virulence factors based on KEGG pathways

scientific article

Deciphering the Relationship between Obesity and Various Diseases from a Network Perspective.

scientific article published on 18 December 2017

Deciphering the effects of gene deletion on yeast longevity using network and machine learning approaches.

scientific article published on 8 January 2012

Determination of Genes Related to Uveitis by Utilization of the Random Walk with Restart Algorithm on a Protein-Protein Interaction Network

scientific article

Discovery of new candidate genes related to brain development using protein interaction information

scientific article published on 30 January 2015

Discriminating between lysine sumoylation and lysine acetylation using mRMR feature selection and analysis

scientific article

Drug target group prediction with multiple drug networks

scientific article published on 01 July 2019

Finding candidate drugs for hepatitis C based on chemical-chemical and chemical-protein interactions

scientific article

Gene Ontology and KEGG Pathway Enrichment Analysis of a Drug Target-Based Classification System

scientific article

Gene expression differences among different MSI statuses in colorectal cancer

scientific article

Gene expression profiling gut microbiota in different races of humans

scientific article

Gene ontology and KEGG enrichment analyses of genes related to age-related macular degeneration

scientific article

Identification of COVID-19 Infection-Related Human Genes Based on a Random Walk Model in a Virus-Human Protein Interaction Network

scientific article published on 08 July 2020

Identification of Differentially Expressed Genes between Original Breast Cancer and Xenograft Using Machine Learning Algorithms.

scientific article published on 12 March 2018

Identification of Genes Associated with Breast Cancer Metastasis to Bone on a Protein-Protein Interaction Network with a Shortest Path Algorithm

scientific article published on 11 January 2017

Identification of Latent Oncogenes with a Network Embedding Method and Random Forest

scientific article published on 23 September 2020

Identification of age-related macular degeneration related genes by applying shortest path algorithm in protein-protein interaction network

scientific article published on 18 December 2013

Identification of compound-protein interactions through the analysis of gene ontology, KEGG enrichment for proteins and molecular fragments of compounds.

scientific article

Identification of gene expression signatures across different types of neural stem cells with the Monte-Carlo feature selection method

scientific article published on 11 November 2017

Identification of hepatocellular carcinoma related genes with k-th shortest paths in a protein-protein interaction network

scientific article published on November 2013

Identification of lung-cancer-related genes with the shortest path approach in a protein-protein interaction network.

scientific article published on 22 May 2013

Identification of new candidate drugs for lung cancer using chemical-chemical interactions, chemical-protein interactions and a K-means clustering algorithm

scientific article published on 5 February 2016

Identification of novel candidate drivers connecting different dysfunctional levels for lung adenocarcinoma using protein-protein interactions and a shortest path approach

scientific article published on 14 July 2016

Identification of synthetic lethality based on a functional network by using machine learning algorithms

scientific article published on 20 August 2018

Identification of the Gene Expression Rules That Define the Subtypes in Glioma

article

Identifying Methylation Pattern and Genes Associated with Breast Cancer Subtypes ⬇️

scientific article published on 31 August 2019

Identifying Patients with Atrioventricular Septal Defect in Down Syndrome Populations by Using Self-Normalizing Neural Networks and Feature Selection.

scientific article published on 12 April 2018

Identifying chemicals with potential therapy of HIV based on protein-protein and protein-chemical interaction network

scientific article (publication date: 2013)

Identifying novel protein phenotype annotations by hybridizing protein-protein interactions and protein sequence similarities.

scientific article published on 4 January 2016

Identifying protein complexes using hybrid properties

scientific article published in November 2009

Integrated Analysis of Multiscale Large-Scale Biological Data for Investigating Human Disease 2016

scientific article

Integrated analysis of multiscale large-scale biological data for investigating human disease.

scientific article published on 20 April 2015

Machine Learning and Network Methods for Biology and Medicine

scientific article published on 29 November 2015

Mining for novel tumor suppressor genes using a shortest path approach

scientific article published on 24 July 2015

Multiple classifier integration for the prediction of protein structural classes.

scientific article

Network-Based Method for Identifying Co- Regeneration Genes in Bone, Dentin, Nerve and Vessel Tissues.

scientific article published on 2 October 2017

Novel computational methods and tools in biomedicine and biopharmacy

scientific article

OPMSP: A Computational Method Integrating Protein Interaction and Sequence Information for the Identification of Novel Putative Oncogenes

scientific article

Predicting Anatomical Therapeutic Chemical (ATC) classification of drugs by integrating chemical-chemical interactions and similarities

scientific article

Predicting chemical toxicity effects based on chemical-chemical interactions

scientific article

Predicting drugs side effects based on chemical-chemical interactions and protein-chemical interactions

scientific article published on 04 September 2013

Predicting metabolic pathways of small molecules and enzymes based on interaction information of chemicals and proteins

scientific article

Predicting subcellular location of proteins using integrated-algorithm method

scientific article published on 7 August 2009

Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition ⬇️

scientific article

Predicting the types of metabolic pathway of compounds using molecular fragments and sequential minimal optimization

scientific article published on 10 November 2015

Predicting triplet of transcription factor – mediating enzyme – target gene by functional profiles

article

Prediction and analysis of cell-penetrating peptides using pseudo-amino acid composition and random forest models

scientific article

Prediction and analysis of retinoblastoma related genes through gene ontology and KEGG.

scientific article published on 13 August 2013

Prediction of Drug Side Effects with a Refined Negative Sample Selection Strategy

scientific article published on 09 May 2020

Prediction of Human Genes’ Regulatory Functions Based on Proteinprotein Interaction Network

article

Prediction of Metabolic Pathway Using Graph Property, Chemical Functional Group and Chemical Structural Set

article

Prediction of cancer drugs by chemical-chemical interactions

scientific article (publication date: 2014)

Prediction of drug target groups based on chemical-chemical similarities and chemical-chemical/protein connections

scientific article published in June 2013

Prediction of drugs target groups based on ChEBI ontology

scientific article published on 20 November 2013

Prediction of effective drug combinations by chemical interaction, protein interaction and target enrichment of KEGG pathways

scientific article published on 05 September 2013

Prediction of gene phenotypes based on GO and KEGG pathway enrichment scores

scientific article

Prediction of interactiveness between small molecules and enzymes by combining gene ontology and compound similarity

scientific article published on June 2010

Prediction of multi-type membrane proteins in human by an integrated approach.

scientific article

Prediction of protein domain with mRMR feature selection and analysis

scientific article

Prediction of protein-protein interaction sites by random forest algorithm with mRMR and IFS

scientific article

Recognition of Immune Cell Markers of COVID-19 Severity with Machine Learning Methods

scientific article published on 28 April 2022

SACICA: a sparse approximation coefficient-based ICA model for functional magnetic resonance imaging data analysis.

scientific article

Signal propagation in protein interaction network during colorectal cancer progression

scientific article published on 20 March 2013

The Use of Chemical-Chemical Interaction and Chemical Structure to Identify New Candidate Chemicals Related to Lung Cancer

scientific article

The Use of Gene Ontology Term and KEGG Pathway Enrichment for Analysis of Drug Half-Life

scientific article

The use of Gene Ontology terms and KEGG pathways for analysis and prediction of oncogenes.

scientific article published on 19 January 2016

Tissue Expression Difference between mRNAs and lncRNAs

scientific article published on 31 October 2018

Using compound similarity and functional domain composition for prediction of drug-target interaction networks

scientific article published in November 2010

Validating the performance of one-time decomposition for fMRI analysis using ICA with automatic target generation process.

scientific article

iATC-NRAKEL: an efficient multi-label classifier for recognizing anatomical therapeutic chemical classes of drugs

scientific article published on 01 March 2020

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