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List of works by Alvan C Hengge

A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases

scientific article published on 28 August 2018

A comparison of phosphonothioic acids with phosphonic acids as phosphatase inhibitors.

scientific article published on August 2003

A concerted mechanism for the transfer of the thiophosphinoyl group from aryl dimethylphosphinothioate esters to oxyanionic nucleophiles in aqueous solution

scientific article

A mechanistic study of the alkaline hydrolysis of diaryl sulfate diesters

scientific article published in December 2004

Altered mechanisms of reactions of phosphate esters bridging a dinuclear metal center

scientific article published in September 2004

Altered transition state for the reaction of an RNA model catalyzed by a dinuclear zinc(II) catalyst

scientific article

An altered mechanism of hydrolysis for a metal-complexed phosphate diester.

scientific article published in December 2002

Chemistry and mechanism of phosphatases, diesterases and triesterases ⬇️

scientific article published on January 1, 2013

Comparison of the reaction progress of calcineurin with Mn2+ and Mg2+.

scientific article published in March 1999

Comparisons of phosphorothioate with phosphate transfer reactions for a monoester, diester, and triester: isotope effect studies

scientific article

Conformational motions regulate phosphoryl transfer in related protein tyrosine phosphatases.

scientific article published on August 2013

Conservative tryptophan mutants of the protein tyrosine phosphatase YopH exhibit impaired WPD-loop function and crystallize with divanadate esters in their active sites

scientific article

Diesterase activity and substrate binding in purple acid phosphatases

scientific article published on 17 July 2007

Enzymatic mechanisms of phosphate and sulfate transfer.

scientific article published on August 2006

Examination of P-OR bridging bond orders in phosphate monoesters using (18)O isotope shifts in 31P NMR.

scientific article published in June 2005

Examination of the transition state of the low-molecular mass small tyrosine phosphatase 1. Comparisons with other protein phosphatases

scientific article published on 01 June 1997

Impaired Acid Catalysis by Mutation of a Protein Loop Hinge Residue in a YopH Mutant Revealed by Crystal Structures

scientific article

Insights into the Phosphoryl Transfer Mechanism of Cyclin-Dependent Protein Kinases from ab Initio QM/MM Free-Energy Studies ⬇️

scientific article published on November 3, 2011

Isotope effect studies on the calcineurin phosphoryl-transfer reaction: transition state structure and effect of calmodulin and Mn2+.

scientific article published in August 1997

Isotope effects and medium effects on sulfuryl transfer reactions

scientific article published in September 2001

Kinetic Isotope Effects and Stereochemical Studies on a Ribonuclease Model: Hydrolysis Reactions of Uridine 3'-Nitrophenyl Phosphate

scientific article published on 01 June 2000

Kinetic isotope effects for alkaline phosphatase reactions: implications for the role of active-site metal ions in catalysis

scientific article

Kinetic isotope effects in the characterization of catalysis by protein tyrosine phosphatases

scientific article published on April 2015

Lanthanide Catalyzed Cyclization of Uridine 3'-p-Nitrophenyl Phosphate

scientific article published on 01 October 2000

Mechanism and transition state structure of aryl methylphosphonate esters doubly coordinated to a dinuclear cobalt(III) center

scientific article published on September 2009

Mechanism of rhodium-catalyzed carbene formation from diazo compounds

scientific article published on 05 April 2007

Mechanistic Aspects of Phosphate Diester Cleavage Assisted by Imidazole. A Template Reaction for Obtaining Aryl Phosphoimidazoles.

scientific article published on 8 July 2016

Mechanistic studies of protein tyrosine phosphatases YopH and Cdc25A with m-nitrobenzyl phosphate.

scientific article published on June 2004

Mechanistic study of protein phosphatase-1 (PP1), a catalytically promiscuous enzyme

scientific article published on 18 September 2008

Metal ion catalyzed hydrolysis of ethyl p-nitrophenyl phosphate

scientific article published in January 2003

Metal-catalyzed phosphodiester cleavage: secondary 18O isotope effects as an indicator of mechanism.

scientific article published in December 2006

Metavanadate at the active site of the phosphatase VHZ

scientific article published on 22 August 2012

Mutation of Arg-166 of Alkaline Phosphatase Alters the Thio Effect but Not the Transition State for Phosphoryl Transfer. Implications for the Interpretation of Thio Effects in Reactions of Phosphatases†

scientific article published in August 2000

NMR data do not implicate a phosphorane in the T4 DNA ligase reaction

scholarly article

Nature of the transition state of the protein-tyrosine phosphatase-catalyzed reaction ⬇️

scientific article published on October 31, 1995

New functional aspects of the atypical protein tyrosine phosphatase VHZ.

scientific article published on 29 October 2013

Probing potential medium effects on phosphate ester bonds using 18O isotope shifts on 31P NMR.

scientific article

Probing the origin of the compromised catalysis of E. coli alkaline phosphatase in its promiscuous sulfatase reaction

scientific article published on 6 April 2007

Probing the transition-state structure of dual-specificity protein phosphatases using a physiological substrate mimic

scientific article published in July 2004

Role of protein conformational mobility in enzyme catalysis: acylation of alpha-chymotrypsin by specific peptide substrates

scientific article

Single Residue on the WPD-Loop Affects the pH Dependency of Catalysis in Protein Tyrosine Phosphatases

scientific article published on 23 April 2021

Structural and Kinetic Properties of the Aldehyde Dehydrogenase NahF, a Broad Substrate Specificity Enzyme for Aldehyde Oxidation.

scientific article published on 31 August 2016

Substrate-Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenes

scientific article

The catalytic mechanism of Cdc25A phosphatase

scientific article published on 22 January 2002

The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis

scientific article published on May 2010

The effects of sulfur substitution for the nucleophile and bridging oxygen atoms in reactions of hydroxyalkyl phosphate esters

scientific article

The mechanism of the phosphoryl transfer catalyzed by Yersinia protein-tyrosine phosphatase: a computational and isotope effect study.

scientific article published on June 2001

The thermodynamics of phosphate versus phosphorothioate ester hydrolysis

scientific article

Thermodynamic origin of the increased rate of hydrolysis of phosphate and phosphorothioate esters in DMSO/water mixtures

scientific article published on September 2006

Transesterification thio effects of phosphate diesters: free energy barriers and kinetic and equilibrium isotope effects from density-functional theory

scientific article published on 01 August 2006

Transition State Analysis of the Reaction Catalyzed by the Phosphotriesterase from Sphingobium sp. TCM1

scientific article published on 19 February 2019

Transition States and Control of Substrate Preference in the Promiscuous Phosphatase PP1.

scientific article

Transition state analysis and requirement of Asp-262 general acid/base catalyst for full activation of dual-specificity phosphatase MKP3 by extracellular regulated kinase

scientific article published in April 2001

Transition state differences in hydrolysis reactions of alkyl versus aryl phosphate monoester monoanions.

scientific article published in October 2003

Transition state of the sulfuryl transfer reaction of estrogen sulfotransferase

scientific article published on 09 August 2006

Transition-State Interactions in a Promiscuous Enzyme: Sulfate and Phosphate Monoester Hydrolysis by Pseudomonas aeruginosa Arylsulfatase

scientific article published on 27 February 2019

Transition-state structures for the native dual-specific phosphatase VHR and D92N and S131A mutants. Contributions to the driving force for catalysis

scientific article published on 01 June 1996

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