List of works - Markus Künzler

A lectin-mediated resistance of higher fungi against predators and parasites.

scientific article published on 12 April 2011

A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds

scientific article published on 24 August 2018

A novel β-trefoil lectin from the parasol mushroom (Macrolepiota procera) is nematotoxic.

scientific article published on 7 July 2014

Activation and repression of the yeast ARO3 gene by global transcription factors

scientific article published on 01 January 1995

Amino acid and adenine cross-pathway regulation act through the same 5'-TGACTC-3' motif in the yeast HIS7 promoter

scientific article published on 01 November 1996

Author Correction: Identification, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A

Correction of a scholarly article

Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products

scientific article

Bacteria-induced production of the antibacterial sesquiterpene lagopodin B in Coprinopsis cinerea

scientific article published on 29 May 2019

Bidirectional Propagation of Signals and Nutrients in Fungal Networks via Specialized Hyphae

scientific article published on 03 January 2019

Biotin-binding proteins in the defense of mushrooms against predators and parasites

scientific article

Biotoxicity assays for fruiting body lectins and other cytoplasmic proteins

scientific article published on January 2010

Bivalent Carbohydrate Binding Is Required for Biological Activity of Clitocybe nebularis Lectin (CNL), the N,N'-Diacetyllactosediamine (GalNAc 1-4GlcNAc, LacdiNAc)-specific Lectin from Basidiomycete C. nebularis

scientific article

Caenorhabditis elegans N-glycan Core β-galactoside Confers Sensitivity towards Nematotoxic Fungal Galectin CGL2

scientific article

Cell surface counter receptors are essential components of the unconventional export machinery of galectin-1.

scientific article published on October 2005

Cloning of the LEU2 gene of Saccharomyces cerevisiae by in vivo recombination

scientific article published on 01 January 1989

Cloning, primary structure and regulation of the ARO4 gene, encoding the tyrosine-inhibited 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Saccharomyces cerevisiae

scientific article published on April 1992

Combining microfluidics and RNA-sequencing to assess the inducible defensome of a mushroom against nematodes

scientific article published on 25 March 2019

Comparative transcriptomics of the model mushroom Coprinopsis cinerea reveals tissue-specific armories and a conserved circuitry for sexual development

scientific article

Coprinopsis cinerea intracellular lactonases hydrolyze quorum sensing molecules of Gram-negative bacteria.

scientific article published on 27 July 2016

Copsin, a novel peptide-based fungal antibiotic interfering with the peptidoglycan synthesis.

scientific article

Correction: Plasticity of the β-Trefoil Protein Fold in the Recognition and Control of Invertebrate Predators and Parasites by a Fungal Defence System

scientific article published on 15 August 2012

Correction: Plasticity of the β-Trefoil Protein Fold in the Recognition and Control of Invertebrate Predators and Parasites by a Fungal Defence System.

scientific article

Crystal Structures of Fungal Tectonin in Complex with O-Methylated Glycans Suggest Key Role in Innate Immune Defense

scientific article published in February 2018

Crystal structure of the putative carbohydrate recognition domain of human galectin-related protein

scientific article

Cse1p functions as the nuclear export receptor for importin alpha in yeast

scientific article published on 01 August 1998

Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes.

scientific article

Discovery of novel fungal RiPP biosynthetic pathways and their application for the development of peptide therapeutics

scientific article published on 31 May 2019

Disruption of the C. elegans Intestinal Brush Border by the Fungal Lectin CCL2 Phenocopies Dietary Lectin Toxicity in Mammals

scientific article

Distinct Autocatalytic α- N-Methylating Precursors Expand the Borosin RiPP Family of Peptide Natural Products

scientific article published on 05 June 2019

Entomotoxic and nematotoxic lectins and protease inhibitors from fungal fruiting bodies.

scientific article

Functional differences between mammalian transcription activation domains at the yeast GAL1 promoter.

scientific article published on February 1994

Galactosylated fucose epitopes in nematodes: increased expression in a Caenorhabditis mutant associated with altered lectin sensitivity and occurrence in parasitic species.

scientific article

Genome sequences of Rhizopogon roseolus, Mariannaea elegans, Myrothecium verrucaria, and Sphaerostilbella broomeana and the identification of biosynthetic gene clusters for fungal peptide natural products

scientific article published in 2022

Heterologous Production and Functional Characterization of Ageritin, a Novel Type of Ribotoxin Highly Expressed during Fruiting of the Edible Mushroom Agrocybe aegerita

scientific article published on 16 October 2019

Hitting the sweet spot-glycans as targets of fungal defense effector proteins.

scientific article published on 06 May 2015

How fungi defend themselves against microbial competitors and animal predators

scholarly article published by Markus Künzler in 2018

Identification and characterization of a novel RanGTP-binding protein in the yeast Saccharomyces cerevisiae.

scientific article

Identification of a Novel Nematotoxic Protein by Challenging the Model Mushroom Coprinopsis cinerea with a Fungivorous Nematode

scientific article

Identification of the galactosyltransferase of Cryptococcus neoformans involved in the biosynthesis of basidiomycete-type glycosylinositolphosphoceramide

scientific article published on 06 August 2013

Identification, characterization, and biosynthesis of a novel N-glycan modification in the fruiting body of the basidiomycete Coprinopsis cinerea.

scientific article

Identification, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A ⬇️

scientific article published on 11 February 2021

Induction of antibacterial proteins and peptides in the coprophilous mushroom Coprinopsis cinerea in response to bacteria

article

Inhibition of Haemonchus contortus larval development by fungal lectins.

scientific article published on 19 August 2015

Injection into and extraction from single fungal cells

scientific article published on 01 March 2022

Ligand interactions of the Coprinopsis cinerea galectins

scientific article

Marasmius oreades agglutinin enhances resistance of Arabidopsis against plant-parasitic nematodes and a herbivorous insect

scientific article published on 01 September 2021

Membrane cholesterol and sphingomyelin, and ostreolysin A are obligatory for pore-formation by a MACPF/CDC-like pore-forming protein, pleurotolysin B.

scientific article

Methylated glycans as conserved targets of animal and fungal innate defense.

scientific article

Molecular analysis of the yeast SER1 gene encoding 3-phosphoserine aminotransferase: regulation by general control and serine repression

scientific article published on May 1995

Molecular basis for galactosylation of core fucose residues in invertebrates: identification of caenorhabditis elegans N-glycan core alpha1,6-fucoside beta1,4-galactosyltransferase GALT-1 as a member of a novel glycosyltransferase family

scientific article published on 26 October 2009

Multi-genome analysis identifies functional and phylogenetic diversity of basidiomycete adenylate-forming reductases

scientific article published on 22 July 2016

Mutations in the YRB1 gene encoding yeast ran-binding-protein-1 that impair nucleocytoplasmic transport and suppress yeast mating defects

scientific article

Mycorrhiza‐induced mycocypins of Laccaria bicolor are potent protease inhibitors with nematotoxic and collembola antifeedant activity

scientific article published in 2022

Nematotoxicity of Marasmius oreades agglutinin (MOA) depends on glycolipid binding and cysteine protease activity.

scientific article

Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence

scientific article published on 10 November 2008

O-Alkylated heavy atom carbohydrate probes for protein X-ray crystallography: Studies towards the synthesis of methyl 2-O-methyl-L-selenofucopyranoside

scientific article published on 22 December 2016

Plasticity of the β-Trefoil Protein Fold in the Recognition and Control of Invertebrate Predators and Parasites by a Fungal Defence System

scientific article

Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis

scientific article

Probing bacterial-fungal interactions at the single cell level.

scientific article published in October 2014

Promoter analysis of cgl2, a galectin encoding gene transcribed during fruiting body formation in Coprinopsis cinerea (Coprinus cinereus).

scientific article published in December 2004

Purification of protein A-tagged yeast ran reveals association with a novel karyopherin beta family member, Pdr6p.

scientific article published in January 2000

Regulation of the yeast HIS7 gene by the global transcription factor Abf1p

scientific article published on 01 September 1997

Structural Basis for Chitotetraose Coordination by CGL3, a Novel Galectin-Related Protein from Coprinopsis cinerea

scientific article

Structural Basis of Trypsin Inhibition and Entomotoxicity of Cospin, Serine Protease Inhibitor Involved in Defense of Coprinopsis cinerea Fruiting Bodies

scientific article

Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity

scientific article published on 01 June 2022

Targeted gene silencing in the model mushroom Coprinopsis cinerea (Coprinus cinereus) by expression of homologous hairpin RNAs

scientific article published on April 2006

The two 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase isoenzymes from Saccharomyces cerevisiae show different kinetic modes of inhibition

scientific article published on 01 June 1998

Toxicity of Potential Fungal Defense Proteins towards the Fungivorous Nematodes Aphelenchus avenae and Bursaphelenchus okinawaensis

article

Uptake of Marasmius oreades agglutinin disrupts integrin-dependent cell adhesion.

scientific article published on 4 November 2015

Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA

scientific article

List of works by Markus Künzler

A lectin-mediated resistance of higher fungi against predators and parasites.

A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds

A novel β-trefoil lectin from the parasol mushroom (Macrolepiota procera) is nematotoxic.

Activation and repression of the yeast ARO3 gene by global transcription factors

Amino acid and adenine cross-pathway regulation act through the same 5'-TGACTC-3' motif in the yeast HIS7 promoter

Author Correction: Identification, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A

Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products

Bacteria-induced production of the antibacterial sesquiterpene lagopodin B in Coprinopsis cinerea

Bidirectional Propagation of Signals and Nutrients in Fungal Networks via Specialized Hyphae

Biotin-binding proteins in the defense of mushrooms against predators and parasites

Biotoxicity assays for fruiting body lectins and other cytoplasmic proteins

Bivalent Carbohydrate Binding Is Required for Biological Activity of Clitocybe nebularis Lectin (CNL), the N,N'-Diacetyllactosediamine (GalNAc 1-4GlcNAc, LacdiNAc)-specific Lectin from Basidiomycete C. nebularis

Caenorhabditis elegans N-glycan Core β-galactoside Confers Sensitivity towards Nematotoxic Fungal Galectin CGL2

Cell surface counter receptors are essential components of the unconventional export machinery of galectin-1.

Cloning of the LEU2 gene of Saccharomyces cerevisiae by in vivo recombination

Cloning, primary structure and regulation of the ARO4 gene, encoding the tyrosine-inhibited 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Saccharomyces cerevisiae

Combining microfluidics and RNA-sequencing to assess the inducible defensome of a mushroom against nematodes

Comparative transcriptomics of the model mushroom Coprinopsis cinerea reveals tissue-specific armories and a conserved circuitry for sexual development

Coprinopsis cinerea intracellular lactonases hydrolyze quorum sensing molecules of Gram-negative bacteria.

Copsin, a novel peptide-based fungal antibiotic interfering with the peptidoglycan synthesis.

Correction: Plasticity of the β-Trefoil Protein Fold in the Recognition and Control of Invertebrate Predators and Parasites by a Fungal Defence System

Correction: Plasticity of the β-Trefoil Protein Fold in the Recognition and Control of Invertebrate Predators and Parasites by a Fungal Defence System.

Crystal Structures of Fungal Tectonin in Complex with O-Methylated Glycans Suggest Key Role in Innate Immune Defense

Crystal structure of the putative carbohydrate recognition domain of human galectin-related protein

Cse1p functions as the nuclear export receptor for importin alpha in yeast

Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes.

Discovery of novel fungal RiPP biosynthetic pathways and their application for the development of peptide therapeutics

Disruption of the C. elegans Intestinal Brush Border by the Fungal Lectin CCL2 Phenocopies Dietary Lectin Toxicity in Mammals

Distinct Autocatalytic α- N-Methylating Precursors Expand the Borosin RiPP Family of Peptide Natural Products

Entomotoxic and nematotoxic lectins and protease inhibitors from fungal fruiting bodies.

Functional differences between mammalian transcription activation domains at the yeast GAL1 promoter.

Galactosylated fucose epitopes in nematodes: increased expression in a Caenorhabditis mutant associated with altered lectin sensitivity and occurrence in parasitic species.

Genome sequences of <i>Rhizopogon roseolus</i>, <i>Mariannaea elegans, Myrothecium verrucaria</i>, and <i>Sphaerostilbella broomeana</i> and the identification of biosynthetic gene clusters for fungal peptide natural products

Heterologous Production and Functional Characterization of Ageritin, a Novel Type of Ribotoxin Highly Expressed during Fruiting of the Edible Mushroom Agrocybe aegerita

Hitting the sweet spot-glycans as targets of fungal defense effector proteins.

How fungi defend themselves against microbial competitors and animal predators

Identification and characterization of a novel RanGTP-binding protein in the yeast Saccharomyces cerevisiae.

Identification of a Novel Nematotoxic Protein by Challenging the Model Mushroom Coprinopsis cinerea with a Fungivorous Nematode

Identification of the galactosyltransferase of Cryptococcus neoformans involved in the biosynthesis of basidiomycete-type glycosylinositolphosphoceramide

Identification, characterization, and biosynthesis of a novel N-glycan modification in the fruiting body of the basidiomycete Coprinopsis cinerea.

Identification, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A ⬇️

Induction of antibacterial proteins and peptides in the coprophilous mushroom Coprinopsis cinerea in response to bacteria

Inhibition of Haemonchus contortus larval development by fungal lectins.

Injection into and extraction from single fungal cells

Ligand interactions of the Coprinopsis cinerea galectins

Marasmius oreades agglutinin enhances resistance of Arabidopsis against plant-parasitic nematodes and a herbivorous insect

Membrane cholesterol and sphingomyelin, and ostreolysin A are obligatory for pore-formation by a MACPF/CDC-like pore-forming protein, pleurotolysin B.

Methylated glycans as conserved targets of animal and fungal innate defense.

Molecular analysis of the yeast SER1 gene encoding 3-phosphoserine aminotransferase: regulation by general control and serine repression

Molecular basis for galactosylation of core fucose residues in invertebrates: identification of caenorhabditis elegans N-glycan core alpha1,6-fucoside beta1,4-galactosyltransferase GALT-1 as a member of a novel glycosyltransferase family

Multi-genome analysis identifies functional and phylogenetic diversity of basidiomycete adenylate-forming reductases

Mutations in the YRB1 gene encoding yeast ran-binding-protein-1 that impair nucleocytoplasmic transport and suppress yeast mating defects

Mycorrhiza‐induced mycocypins of <i>Laccaria bicolor</i> are potent protease inhibitors with nematotoxic and collembola antifeedant activity

Nematotoxicity of Marasmius oreades agglutinin (MOA) depends on glycolipid binding and cysteine protease activity.

Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence

O-Alkylated heavy atom carbohydrate probes for protein X-ray crystallography: Studies towards the synthesis of methyl 2-O-methyl-L-selenofucopyranoside

Plasticity of the β-Trefoil Protein Fold in the Recognition and Control of Invertebrate Predators and Parasites by a Fungal Defence System

Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis

Probing bacterial-fungal interactions at the single cell level.

Promoter analysis of cgl2, a galectin encoding gene transcribed during fruiting body formation in Coprinopsis cinerea (Coprinus cinereus).

Purification of protein A-tagged yeast ran reveals association with a novel karyopherin beta family member, Pdr6p.

Regulation of the yeast HIS7 gene by the global transcription factor Abf1p

Structural Basis for Chitotetraose Coordination by CGL3, a Novel Galectin-Related Protein from Coprinopsis cinerea

Structural Basis of Trypsin Inhibition and Entomotoxicity of Cospin, Serine Protease Inhibitor Involved in Defense of Coprinopsis cinerea Fruiting Bodies

Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity

Targeted gene silencing in the model mushroom Coprinopsis cinerea (Coprinus cinereus) by expression of homologous hairpin RNAs

The two 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase isoenzymes from Saccharomyces cerevisiae show different kinetic modes of inhibition

Toxicity of Potential Fungal Defense Proteins towards the Fungivorous Nematodes Aphelenchus avenae and Bursaphelenchus okinawaensis

Uptake of Marasmius oreades agglutinin disrupts integrin-dependent cell adhesion.

Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA