List of works - Uttam Surana

"Reductional anaphase" in replication-defective cells is caused by ubiquitin-conjugating enzyme Cdc34-mediated deregulation of the spindle.

scientific article

A multi-scale model of the yeast chromosome-segregation system

A novel cell cycle inhibitor stalls replication forks and activates S phase checkpoint.

scientific article

An improved pre-clinical patient-derived liquid xenograft mouse model for acute myeloid leukemia

scientific article published on 6 October 2017

Arabidopsis profilins are functionally similar to yeast profilins: identification of a vascular bundle-specific profilin and a pollen-specific profilin.

scientific article published in August 1996

Blau Syndrome Associated with Nucleotide-binding Oligomerization Domain Containing 2 Mutation in a Baby from Malaysia

scientific article published on 01 September 2019

Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo

Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo.

scientific article

CHILD syndrome in a Malaysian adult with identification of a novel heterozygous missense mutation NSDHL c.602A>G

scientific article published on 10 November 2020

Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast.

scientific article

Cdc20 protein contains a destruction-box but, unlike Clb2, its proteolysisis not acutely dependent on the activity of anaphase-promoting complex

scientific article published on 01 January 2000

Cdc20, a β-transducin homologue, links RAD9 -mediated G2/M checkpoint control to mitosis in Saccharomyces cerevisiae

scientific article published on 01 November 1996

Cdc28-Clb mitotic kinase negatively regulates bud site assembly in the budding yeast

scientific article published on 01 January 2001

Cdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiae

scientific article

Cdc42-dependent localization of polarisome component Spa2 to the incipient bud site is independent of the GDP/GTP exchange factor Cdc24.

scientific article

Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest

scientific article

Cdk1 regulates centrosome separation by restraining proteolysis of microtubule-associated proteins

scientific article

Chaperoning HMGA2 protein protects stalled replication forks in stem and cancer cells.

scientific article published on 6 February 2014

Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae ⬇️

scientific article published on July 1, 1992

Condensin recruitment to chromatin is inhibited by Chk2 kinase in response to DNA damage

scientific article published on 28 October 2016

Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket

scientific article published on 16 May 2018

Consorting kinases, end of destruction and birth of a spindle

scientific article published on 13 October 2008

DNA damage checkpoint maintains CDH1 in an active state to inhibit anaphase progression.

scientific article

DNA replication checkpoint prevents precocious chromosome segregation by regulating spindle behavior

scientific article published in December 2004

DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour agent

scientific article

Deficiency of centromere-associated protein Slk19 causes premature nuclear migration and loss of centromeric elasticity

scientific article

Dependence of pre-mRNA introns on PRP17, a non-essential splicing factor: implications for efficient progression through cell cycle transitions

scientific article

Dephosphorylation of threonine 169 of Cdc28 is not required for exit from mitosis but may be necessary for start in Saccharomyces cerevisiae.

scientific article published on August 1996

Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast

scientific article

Disjunction of conjoined twins: Cdk1, Cdh1 and separation of centrosomes

scientific article published on 22 June 2006

Early expressed Clb proteins allow accumulation of mitotic cyclin by inactivating proteolytic machinery during S phase

scientific article

Electron cryotomography analysis of Dam1C/DASH at the kinetochore–spindle interface in situ

scientific article published on 30 November 2018

Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit

scientific article

Exit from Mitosis in Budding Yeast

scientific article published on 01 March 2000

Factors contributing to helical shape determination and maintenance in Bacillus subtilis macrofibres

scientific article published on 01 January 1985

Faculty of 1000 evaluation for The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrest

H syndrome - the first report in Malaysia

scientific article published on 13 June 2019

Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing

scientific article

Identification of novel homozygous SLURP1 mutation in a Javanese family with Mal de Meleda.

scientific article

Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle

scientific article

Inactivation of mitotic kinase triggers translocation of MEN components to mother-daughter neck in yeast

scientific article

Induced-Decay of Glycine Decarboxylase Transcripts as an Anticancer Therapeutic Strategy for Non-Small-Cell Lung Carcinoma.

scientific article published on 7 October 2017

MEN, destruction and separation: mechanistic links between mitotic exit and cytokinesis in budding yeast

scientific article

Mapping Mitotic Death: Functional Integration of Mitochondria, Spindle Assembly Checkpoint and Apoptosis

scientific article published on 01 January 2018

Mechanical properties of Bacillus subtilis cell walls: effects of ions and lysozyme.

scientific article published on January 1991

Molecular and genetic characterization of SLC1, a putative Saccharomyces cerevisiae homolog of the metazoan cytoplasmic dynein light chain 1.

scientific article published in April 1996

NDD1, a high-dosage suppressor of cdc28-1N, is essential for expression of a subset of late-S-phase-specific genes in Saccharomyces cerevisiae

scientific article

Oscillations of the p53-Akt network: implications on cell survival and death

scientific article

Regulation of centrosome separation in yeast and vertebrates: common threads

scientific article

Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae

scientific article

Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress

scientific article published on 31 July 2017

Resistance to anti-microtubule drug-induced cell death is determined by regulation of BimEL expression

scientific article published on 15 February 2019

Solubilization and preformulation of poorly water soluble and hydrolysis susceptible N-epoxymethyl-1,8-naphthalimide (ENA) compound

scientific article

Some Facts and Thoughts on Cell Cycle Control in Yeast ⬇️

scientific article published on January 1, 1991

Spindle pole body separation in Saccharomyces cerevisiae requires dephosphorylation of the tyrosine 19 residue of Cdc28.

scientific article

Staging a recovery from mitotic arrest: Unusual ways of Cdk1

scientific article published on February 2012

Synthesizing non-natural parts from natural genomic template

scientific article

Taming the spindle for containing the chromosomes

scientific article

The "suppressive side" of yeast mitotic cyclins.

scientific article published on 15 September 2011

The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae

scientific article

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5.

scientific article

Tome-1, wee1, and the onset of mitosis: coupled destruction for timely entry

scientific article

Transcription factor oscillations induce differential gene expressions

scientific article published on 5 June 2012

Tying the knot: linking cytokinesis to the nuclear cycle.

scientific article

p38 mitogen-activated protein kinase promotes cell survival in response to DNA damage but is not required for the G(2) DNA damage checkpoint in human cancer cells

scientific article

List of works by Uttam Surana

"Reductional anaphase" in replication-defective cells is caused by ubiquitin-conjugating enzyme Cdc34-mediated deregulation of the spindle.

A multi-scale model of the yeast chromosome-segregation system

A novel cell cycle inhibitor stalls replication forks and activates S phase checkpoint.

An improved pre-clinical patient-derived liquid xenograft mouse model for acute myeloid leukemia

Arabidopsis profilins are functionally similar to yeast profilins: identification of a vascular bundle-specific profilin and a pollen-specific profilin.

Blau Syndrome Associated with Nucleotide-binding Oligomerization Domain Containing 2 Mutation in a Baby from Malaysia

Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo

Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo.

CHILD syndrome in a Malaysian adult with identification of a novel heterozygous missense mutation NSDHL c.602A>G

Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast.

Cdc20 protein contains a destruction-box but, unlike Clb2, its proteolysisis not acutely dependent on the activity of anaphase-promoting complex

Cdc20, a β-transducin homologue, links RAD9 -mediated G2/M checkpoint control to mitosis in Saccharomyces cerevisiae

Cdc28-Clb mitotic kinase negatively regulates bud site assembly in the budding yeast

Cdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiae

Cdc42-dependent localization of polarisome component Spa2 to the incipient bud site is independent of the GDP/GTP exchange factor Cdc24.

Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest

Cdk1 regulates centrosome separation by restraining proteolysis of microtubule-associated proteins

Chaperoning HMGA2 protein protects stalled replication forks in stem and cancer cells.

Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae ⬇️

Condensin recruitment to chromatin is inhibited by Chk2 kinase in response to DNA damage

Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket

Consorting kinases, end of destruction and birth of a spindle

DNA damage checkpoint maintains CDH1 in an active state to inhibit anaphase progression.

DNA replication checkpoint prevents precocious chromosome segregation by regulating spindle behavior

DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour agent

Deficiency of centromere-associated protein Slk19 causes premature nuclear migration and loss of centromeric elasticity

Dependence of pre-mRNA introns on PRP17, a non-essential splicing factor: implications for efficient progression through cell cycle transitions

Dephosphorylation of threonine 169 of Cdc28 is not required for exit from mitosis but may be necessary for start in Saccharomyces cerevisiae.

Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast

Disjunction of conjoined twins: Cdk1, Cdh1 and separation of centrosomes

Early expressed Clb proteins allow accumulation of mitotic cyclin by inactivating proteolytic machinery during S phase

Electron cryotomography analysis of Dam1C/DASH at the kinetochore–spindle interface in situ

Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit

Exit from Mitosis in Budding Yeast

Factors contributing to helical shape determination and maintenance in Bacillus subtilis macrofibres

Faculty of 1000 evaluation for The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrest

H syndrome - the first report in Malaysia

Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing

Identification of novel homozygous SLURP1 mutation in a Javanese family with Mal de Meleda.

Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle

Inactivation of mitotic kinase triggers translocation of MEN components to mother-daughter neck in yeast

Induced-Decay of Glycine Decarboxylase Transcripts as an Anticancer Therapeutic Strategy for Non-Small-Cell Lung Carcinoma.

MEN, destruction and separation: mechanistic links between mitotic exit and cytokinesis in budding yeast

Mapping Mitotic Death: Functional Integration of Mitochondria, Spindle Assembly Checkpoint and Apoptosis

Mechanical properties of Bacillus subtilis cell walls: effects of ions and lysozyme.

Molecular and genetic characterization of SLC1, a putative Saccharomyces cerevisiae homolog of the metazoan cytoplasmic dynein light chain 1.

NDD1, a high-dosage suppressor of cdc28-1N, is essential for expression of a subset of late-S-phase-specific genes in Saccharomyces cerevisiae

Oscillations of the p53-Akt network: implications on cell survival and death

Regulation of centrosome separation in yeast and vertebrates: common threads

Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae

Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress

Resistance to anti-microtubule drug-induced cell death is determined by regulation of BimEL expression

Solubilization and preformulation of poorly water soluble and hydrolysis susceptible N-epoxymethyl-1,8-naphthalimide (ENA) compound

Some Facts and Thoughts on Cell Cycle Control in Yeast ⬇️

Spindle pole body separation in Saccharomyces cerevisiae requires dephosphorylation of the tyrosine 19 residue of Cdc28.

Staging a recovery from mitotic arrest: Unusual ways of Cdk1

Synthesizing non-natural parts from natural genomic template

Taming the spindle for containing the chromosomes

The "suppressive side" of yeast mitotic cyclins.

The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5.

Tome-1, wee1, and the onset of mitosis: coupled destruction for timely entry

Transcription factor oscillations induce differential gene expressions

Tying the knot: linking cytokinesis to the nuclear cycle.

p38 mitogen-activated protein kinase promotes cell survival in response to DNA damage but is not required for the G(2) DNA damage checkpoint in human cancer cells