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List of works by Stefan H. Heinemann

A characterization of the activating structural rearrangements in voltage-dependent Shaker K+ channels

scientific article published in February 1994

A de novo gain-of-function mutation in SCN11A causes loss of pain perception

scientific article

A delta-conotoxin from Conus ermineus venom inhibits inactivation in vertebrate neuronal Na+ channels but not in skeletal and cardiac muscles.

scientific article published on 13 November 2003

A mutually exclusive alternative exon of slo1 codes for a neuronal BK channel with altered function.

scientific article

A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors

scientific article

A point mutation in the human Slo1 channel that impairs its sensitivity to omega-3 docosahexaenoic acid.

scientific article published on 14 October 2013

A room temperature ionic liquid as convenient solvent for the oxidative folding of conopeptides.

scientific article

A second human methionine sulfoxide reductase (hMSRB2) reducing methionine-R-sulfoxide displays a tissue expression pattern distinct from hMSRB1

scientific article (publication date: 2003)

A site accessible to extracellular TEA+ and K+ influences intracellular Mg2+ block of cloned potassium channels

scientific article published in January 1993

A subtle alternative splicing event of the Na(V)1.8 voltage-gated sodium channel is conserved in human, rat, and mouse.

scientific article

A versatile transport network for sequestering and excreting plant glycosides in leaf beetles provides an evolutionary flexible defense strategy

scientific article published in September 2009

Activity, tissue distribution and site-directed mutagenesis of a human peptide methionine sulfoxide reductase of type B: hCBS1

scientific article (publication date: 11 September 2002)

Amino terminal‐dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment ⬇️

scientific article published on August 1, 1997

An approach to NMR assignment of intrinsically disordered proteins

scientific article published on 30 January 2015

Analysis of Fe(III) heme binding to cysteine-containing heme-regulatory motifs in proteins.

scientific article published on 17 June 2013

Apomyoglobin reveals a random-nucleation mechanism in amyloid protofibril formation

scientific article published on 22 May 2006

Application of Room-Temperature Aprotic and Protic Ionic Liquids for Oxidative Folding of Cysteine-Rich Peptides

scientific article published on 05 November 2014

Atomic determinants of BK channel activation by polyunsaturated fatty acids

scientific article

BKCa channels activating at resting potential without calcium in LNCaP prostate cancer cells.

scientific article published on December 2005

Bioactivity of topologically confined gramicidin A dimers.

scientific article

CORM-EDE1: A Highly Water-Soluble and Nontoxic Manganese-Based photoCORM with a Biogenic Ligand Sphere

scientific article published on 16 December 2015

Ca(2+)/calmodulin regulates Kvβ1.1-mediated inactivation of voltage-gated K(+) channels

scientific article published on 21 October 2015

Capillary electrophoresis separation of peptide diastereomers that contain methionine sulfoxide by dual cyclodextrin-crown ether systems

scientific article published on 20 October 2014

Carbon monoxide and outcome of stroke--a dream CORM true?.

scientific article published in February 2012

Carbon monoxide release properties and molecular structures of phenylthiolatomanganese(I) carbonyl complexes of the type [(OC)4Mn(μ-S-aryl)]2

scientific article published on 01 February 2015

Carbon monoxide--physiology, detection and controlled release.

scientific article

Cold-aggravated pain in humans caused by a hyperactive NaV1.9 channel mutant

scientific article

Combination of patch clamp and Raman spectroscopy for single-cell analysis

scientific article published on 08 December 2010

Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhalphaIT with sodium channel receptor sites-3.

scientific article published in March 2004

Conformational switch between slow and fast gating modes: allosteric regulation of voltage sensor mobility in the EAG K+ channel

scientific article published on 01 August 2002

Conotoxins of the O-superfamily affecting voltage-gated sodium channels.

scientific article published on June 2007

Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons.

scientific article

Current inhibition of human EAG1 potassium channels by the Ca2+ binding protein S100B

scientific article

Cyclosporin A selectively reduces the functional expression of Kir2.1 potassium channels in Xenopus oocytes

scientific article published in February 1998

Cysteine 723 in the C-linker segment confers oxidative inhibition of hERG1 potassium channels.

scientific article published on 14 June 2010

Cysteines control the N- and C-linker-dependent gating of KCNH1 potassium channels

scientific article published on 28 January 2012

Determination of hemin-binding characteristics of proteins by a combinatorial peptide library approach.

scientific article

Dicarbonyl-bis(cysteamine)iron(II): a light induced carbon monoxide releasing molecule based on iron (CORM-S1)

scientific article published on 15 October 2010

Differential sensitivity of sodium channels from the central and peripheral nervous system to the scorpion toxins Lqh-2 and Lqh-3

scientific article published on 01 August 2002

Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels

scientific article

Effect of Conformational Diversity on the Bioactivity of µ-Conotoxin PIIIA Disulfide Isomers

scientific article published on 02 July 2019

Effect of depolarization on binding kinetics of scorpion alpha-toxin highlights conformational changes of rat brain sodium channels

scientific article published in December 2001

Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells

scientific article published in July 2002

Error estimates for results of nonstationary noise analysis derived with linear least squares methods

scientific article published on December 1997

Estimation of Na+ dwell time in the gramicidin A channel. Na+ ions as blockers of H+ currents.

scientific article

Exon 11 skipping of SCN10A coding for voltage-gated sodium channels in dorsal root ganglia

scientific article

Experimental design-guided development of a stereospecific capillary electrophoresis assay for methionine sulfoxide reductase enzymes using a diastereomeric pentapeptide substrate

scientific article published on 12 July 2014

Expression of ether à go-go potassium channels in human gliomas.

scientific article published in September 2004

Expression of the voltage- and Ca2+-dependent BK potassium channel subunits BKβ1 and BKβ4 in rodent astrocytes

scientific article published on 24 March 2011

Extracellular Mg2+ regulates activation of rat eag potassium channel

scientific article published in June 1996

Fixed charges in the gel matrix of sensor chips and dissociation in diffusion gradients influence the detection of fast protein-protein interactions.

scientific article published on 14 December 2013

Four novel sequences in Drosophila melanogaster homologous to the auxiliary Para sodium channel subunit TipE.

scientific article published on 28 November 2005

Functional consequences of methionine oxidation of hERG potassium channels.

scientific article published on 07 June 2007

Functional distinction of human EAG1 and EAG2 potassium channels

scientific article (publication date: 13 March 2002)

Gating currents of inactivating and non-inactivating potassium channels expressed in Xenopus oocytes

scientific article published in May 1991

Gene Polymorphisms in the Heme Degradation Pathway and Outcome of Severe Human Sepsis

scientific article published on 01 November 2012

H2O2-induced chloride currents are indicative of an endogenous Na(+)-Ca2+ exchange mechanism in Xenopus oocytes

scientific article published in July 1995

Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels

scientific article

Heme impairs the ball-and-chain inactivation of potassium channels

scientific article published on 30 September 2013

Heme regulates allosteric activation of the Slo1 BK channel

scientific article

Heterologous expression of NaV1.9 chimeras in various cell systems

scientific article published on 29 April 2015

High-quality life extension by the enzyme peptide methionine sulfoxide reductase

scientific article

Human EAG channels are directly modulated by PIP2 as revealed by electrophysiological and optical interference investigations

scientific journal article

Identification of a new functional splice variant of the enzyme methionine sulphoxide reductase A (MSRA) expressed in rat vascular smooth muscle cells

scientific journal article

Identification of ether à go-go and calcium-activated potassium channels in human melanoma cells

scientific article published on 01 September 1999

Impact of intracellular hemin on N-type inactivation of voltage-gated K+ channels

scientific article published on 10 May 2020

Individual subunits contribute independently to slow gating of bovine EAG potassium channels

scientific article published on 01 February 1999

Inhibition of human ether à go-go potassium channels by Ca2+/calmodulin binding to the cytosolic N- and C-termini

scientific article

Interaction of scorpion alpha-toxins with cardiac sodium channels: binding properties and enhancement of slow inactivation

scientific article published on June 2001

Ion conduction through C-type inactivated Shaker channels.

scientific article

Isolation, molecular cloning and functional characterization of a novel beta-toxin from the Venezuelan scorpion, Tityus zulianus

scientific article published on 01 May 2004

Kcnh1 voltage-gated potassium channels are essential for early zebrafish development

scientific article

Macroscopic Na+ Currents in the “Nonconducting” Shaker Potassium Channel Mutant W434F ⬇️

scientific article published on July 1, 1998

Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II.

scientific article published in November 1991

Mechanism and molecular basis for the sodium channel subtype specificity of µ-conopeptide CnIIIC

scientific article published on October 2012

Mechanism of the modulation of BK potassium channel complexes with different auxiliary subunit compositions by the omega-3 fatty acid DHA.

scientific article published on 4 March 2013

Mechanisms of the inhibition of Shaker potassium channels by protons

scientific article published on 12 August 2003

Metabolic regulation of potassium channels.

scientific article published on January 2004

Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms.

scientific article published in November 2007

Methionine sulfoxide reductase A protects neuronal cells against brief hypoxia/reoxygenation

scholarly article

Methionine-oxidized amyloid fibrils are poor substrates for human methionine sulfoxide reductases A and B2.

scientific article published in April 2010

Modification of C-type inactivating Shaker potassium channels by chloramine-T

scientific article published on 01 February 1996

Modulation of BK Channels by Small Endogenous Molecules and Pharmaceutical Channel Openers

scientific article published on 4 May 2016

Modulation of K channel N-type inactivation by sulfhydration through hydrogen sulfide and polysulfides

scientific article published on 10 November 2018

Modulation of cloned skeletal muscle sodium channels by the scorpion toxins Lqh II, Lqh III, and Lqh alphaIT

scientific article published on 01 February 2000

Modulation of mu opioid receptor desensitization in peripheral sensory neurons by phosphoinositide 3-kinase gamma

scientific article published on 6 May 2010

Modulation of potassium channel function by methionine oxidation and reduction ⬇️

scientific article published on September 2, 1997

Molecular Insights into the Mechanism of Calmodulin Inhibition of the EAG1 Potassium Channel

scientific article

Molecular basis for different pore properties of potassium channels from the rat brain Kv1 gene family

scientific article published in November 1997

Molecular basis for pharmacological differences between brain and cardiac sodium channels

scientific article published in October 1992

Molecular cloning and expression of cERG, the ether à go-go-related gene from canine myocardium

scientific article published in May 2001

Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents

scientific article published in May 2004

Molecular determinants for the subtype specificity of μ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels

scientific article

Molecular interaction of delta-conotoxins with voltage-gated sodium channels.

scientific article

Molecular interaction of δ-conopeptide EVIA with voltage-gated Na(+) channels

scientific article published on 15 June 2016

Molecular mechanism of pharmacological activation of BK channels.

scientific article published on 13 February 2012

Monitoring of compound resting membrane potentials of cell cultures with ratiometric genetically encoded voltage indicators

scientific article published on 07 October 2021

Multicentre study on standardisation of melanoma cell culture - an initiative of the German Melanoma Research Network

article

Multifunctional potassium channels: electrical switches and redox enzymes, all in one

scientific article published on 29 August 2006

Multiple PIP2 binding sites in Kir2.1 inwardly rectifying potassium channels.

scientific article

N-Terminal deletions of rKv1.4 channels affect the voltage dependence of channel availability

scientific article published on 01 July 1999

Nitric oxide augments voltage-gated P/Q-type Ca(2+) channels constituting a putative positive feedback loop.

scientific article

Omega-3 fatty acids lower blood pressure by directly activating large-conductance Ca²⁺-dependent K⁺ channels.

scientific article published on 4 March 2013

Oxidation of multiple methionine residues impairs rapid sodium channel inactivation

scientific article published on 28 March 2008

Oxidative damage, aging and anti-aging strategies.

scientific article

Oxidative modulation of voltage-gated potassium channels

scientific article

Phosphoinositide 3-kinase-gamma induces Xenopus oocyte maturation via lipid kinase activity

scientific article

Photo-modulated ion channels based on covalently linked gramicidins

scientific article

Pore properties of rat brain II sodium channels mutated in the selectivity filter domain

scientific article published in January 1996

Probing pore topology and conformational changes of Kir2.1 potassium channels by cysteine scanning mutagenesis

scientific article published on 01 September 1998

Protection of vascular smooth muscle cells by over-expressed methionine sulphoxide reductase A: role of intracellular localization and substrate availability

scientific article published on November 2008

Reactive oxygen species and nitric oxide mediate plasticity of neuronal calcium signaling.

scientific article published on January 2000

Reactive oxygen species impair Slo1 BK channel function by altering cysteine-mediated calcium sensing

scientific article published on 25 January 2004

Reactive species modify NaV1.8 channels and affect action potentials in murine dorsal root ganglion neurons.

scientific article published on 17 September 2015

Reciprocal regulation of the Ca2+ and H+ sensitivity in the SLO1 BK channel conferred by the RCK1 domain

scientific article

Regulation of voltage-dependent K+ channels by methionine oxidation: effect of nitric oxide and vitamin C.

scientific article published in January 1999

Reply to Harris et al.: Differential impacts of omega-3 fatty acids and their derivatives on blood pressure

scientific article published in June 2013

Scorpion alpha and alpha-like toxins differentially interact with sodium channels in mammalian CNS and periphery

scientific article published on 01 August 2000

Scorpion β-toxin interference with NaV channel voltage sensor gives rise to excitatory and depressant modes

scientific article published on April 2012

Sodium channels as gateable non-photonic sensors for membrane-delimited reactive species

scientific article

Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241.

scientific article published in September 1997

Stereospecific capillary electrophoresis assays using pentapeptide substrates for the study ofAspergillus nidulansmethionine sulfoxide reductase A and mutant enzymes

scientific article published on 08 June 2016

Stereospecific electrophoretically mediated microanalysis assay for methionine sulfoxide reductase enzymes

scientific article

Stereospecific micellar electrokinetic chromatography assay of methionine sulfoxide reductase activity employing a multiple layer coated capillary.

scientific article

Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV 1.4.

scientific article published on 12 March 2012

Structure Elucidation and Activity of Kolossin A, the D-/L-Pentadecapeptide Product of a Giant Nonribosomal Peptide Synthetase

scientific article

Structure-function relationship in an archaebacterial methionine sulphoxide reductase B

scientific article

Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3.

scientific article published on 25 April 2006

Subtype-specific block of voltage-gated K+ channels by μ-conopeptides.

scientific article published in December 2016

Synthesis and solution stability of water-soluble κ2N,κO-bis(3,5-dimethylpyrazolyl)ethanol manganese(i) tricarbonyl bromide (CORM-ONN1).

scientific article published on 19 January 2017

TRPgamma channels are inhibited by cAMP and contribute to pacemaking in neurosecretory insect neurons

scientific article published on 30 November 2005

Temperature and pressure dependence of Shaker K+ channel N- and C-type inactivation.

scientific article published in January 1997

The amiodarone derivative 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015) opens large-conductance Ca2+-activated K+ channels and relaxes vascular smooth muscle.

scientific article published on 28 October 2006

The amiodarone derivative KB130015 activates hERG1 potassium channels via a novel mechanism

scientific article

The inactivation behaviour of voltage-gated K-channels may be determined by association of alpha- and beta-subunits

scientific article published in January 1994

The influence of statins on the free intracellular calcium concentration in human umbilical vein endothelial cells

scientific article

The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes

scientific article published on March 1997

The muO-conotoxin MrVIA inhibits voltage-gated sodium channels by associating with domain-3.

scientific article published on 26 January 2006

The repair enzyme peptide methionine-S-sulfoxide reductase is expressed in human epidermis and upregulated by UVA radiation

scientific article published in May 2006

The satiety signaling neuropeptide perisulfakinin inhibits the activity of central neurons promoting general activity

scientific article published on 30 December 2007

The unique pharmacology of the scorpion alpha-like toxin Lqh3 is associated with its flexible C-tail.

scientific article published on 9 March 2007

Three methionine residues located within the regulator of conductance for K+ (RCK) domains confer oxidative sensitivity to large-conductance Ca2+-activated K+ channels.

scientific article published on 5 January 2006

Two distinct effects of PIP2 underlie auxiliary subunit-dependent modulation of Slo1 BK channels.

scientific article

Two-electrode voltage clamp of Xenopus oocytes under high hydrostatic pressure

scientific article

Visualizing Individual Sodium Channels on the Move ⬇️

scientific article published on July 27, 2012

Voltage-dependent ion channels: analysis of nonideal macroscopic current data.

scientific article

Zn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain.

scientific article

dOr83b--receptor or ion channel?

scientific article

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