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List of works by Paolo Puccetti

A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression

scientific article published on 27 July 2012

A TH1-TH2-like switch in candidiasis: new perspectives for therapy.

scientific article published on June 1995

A crucial role for tryptophan catabolism at the host/Candida albicans interface.

scientific article

A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice

scientific article

A radiolabel release microassay for phagocytic killing of Candida albicans

scientific article published on 01 August 1982

A retroviral peptide encoded by mutated env p15E gene is recognized by specific CD8+ T lymphocytes on drug-treated murine mastocytoma P815.

scientific article published in October 1996

Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers

scientific article published on 16 April 2015

Activation of mouse macrophages by pyran copolymer and role in augmentation of natural killer activity ⬇️

scientific article published on December 15, 1979

Adaptation of Candida albicans to the host environment: the role of morphogenesis in virulence and survival in mammalian hosts

scientific article

Adoptive immunotherapy of intracerebral murine lymphomas: role of different lymphoid populations

scientific article published in May 1985

Adriamycin-induced antitumor response in lethally irradiated mice ⬇️

scientific article published on June 1, 1979

AhR: far more than an environmental sensor

scientific article published in January 2014

Antagonistic effect of IL-2 on DTIC-induced impairment of tumor-specific cell-mediated immunity in vitro

scientific article

Antibacterial resistance induced by recombinant interleukin 1 in myelosuppressed mice: effect of treatment schedule and correlation with colony-stimulating activity in the bloodstream

scientific article published in June 1990

Anticancer drug toxicity via cytokine production: the hydroxyurea paradigm

scientific article published on 01 December 1995

Antigen-specific cytolysis of infected cells in murine candidiasis

scientific article published on 01 May 1992

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

scientific article

Augmentation of natural killer activity by pyran copolymer in mice

scientific article published on 01 November 1979

Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans

scientific article published on 6 May 2009

CD103(+) Dendritic Cells Control Th17 Cell Function in the Lung

scientific article published on 9 September 2015

CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.

scientific article published on 3 October 2004

CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig.

scientific article published in June 2005

CTLA-4, T helper lymphocytes and dendritic cells: an internal perspective of T-cell homeostasis.

scientific article

CTLA-4-Ig regulates tryptophan catabolism in vivo.

scientific article published on 30 September 2002

Cell-mediated immunity to chemically xenogenized tumors--IV. Production of lymphokine activity by, and in response to, highly immunogenic cells.

scientific article published in January 1989

Cell-mediated immunity to chemically xenogenized tumors--VI. The effect of cell treatment with retroviral env antisense oligonucleotides

scientific article published on 01 July 1993

Cell-mediated immunity to chemically xenogenized tumors. I. Inhibition by specific antisera and H-2 association of the novel antigens.

scientific article published in January 1988

Cell-mediated immunity to chemically xenogenized tumors. II. Evidence for accessory function and self-antigen presentation by a highly immunogenic tumor variant

scientific article published on February 1988

Cell-mediated immunity to chemically xenogenized tumors. V. Failure of novel antigens to increase the frequency of tumor-specific cytotoxic T cells

scientific article published on 01 January 1990

Cell-mediated immunity to chemically xenogenized tumors—III. Generation of monoclonal antibodies interfering with reactivity to novel antigens

scientific article published on 01 January 1988

Changes in the tumorigenic and metastatic properties of murine melanoma cells treated with a triazene derivative

scientific article published on May 1989

Chemical xenogenization of experimental tumors

scientific article published on January 1987

Chemical xenogenization of murine lymphoma cells with triazene derivatives: immunotoxicological studies

scientific article published on January 1984

Chronic granulomatous disease

scientific article published on 01 February 2009

Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells.

scientific article published in November 1997

Clotting factor concentrate switching and inhibitor development in hemophilia A.

scientific article published on 12 June 2012

Combined effects of antineoplastic agents and anti-lymphoma allograft reactions

scientific article published on 01 January 1980

Combined effects of chemotherapy and host antitumor response in a murine histocompatible lymphoma model

scientific article published on 01 January 1984

Comparative proteomic analysis of two distinct stem-cell populations from human amniotic fluid

scientific article published on 26 March 2015

Controlling pathogenic inflammation to fungi

scientific article published on December 2007

CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis.

scientific article published on 05 March 2017

Cytokines and tumours: problems and perspectives.

scientific article published on February 1994

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

scientific article

Depression of hepatic biotransformations by chemical immunoadjuvants

scientific article published on 01 January 1981

Dna methylating activity in murine lymphoma cells xenogenized by triazene derivatives

scientific article published on 01 June 1987

Drugs and the immune system: the emerging era of immunopharmacology

scientific article published on 01 April 2001

Dual effect of IL-4 on resistance to systemic gram-negative infection and production of TNF-alpha

scientific article published on 01 April 2000

Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12.

scientific article

Enhancement of natural killer cell activity in mice by treatment with a thymic factor

scientific article published on 01 January 1984

Evidence for tumor necrosis factor α as a mediator of the toxicity of a cyclooxygenase inhibitor in Gram-negative sepsis

article

Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes

scientific article

Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc.

scientific article published in November 2007

Fungi, dendritic cells and receptors: a host perspective of fungal virulence

scientific article

Generation of T cell regulatory activity by plasmacytoid dendritic cells and tryptophan catabolism.

scientific article published on 18 September 2007

Generation of monoclonal antibodies to a chemically xenogenized murine lymphoma

scientific article published on 01 May 1988

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction.

scientific article published in May 2010

HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53-dependent mitochondrial apoptosis

scientific article published on 23 December 2019

High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway.

scientific article published in January 2013

IDO mediates TLR9-driven protection from experimental autoimmune diabetes.

scientific article published on 19 October 2009

IL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 Production

scientific article published on 01 September 1998

IL-12 INDUCES SDS-STABLE CLASS II αβ DIMERS IN MURINE DENDRITIC CELLS

scientific article published on 01 April 2000

IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi

scientific article published on April 2008

IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis

scientific article (publication date: 2013)

IL-22 defines a novel immune pathway of antifungal resistance.

scientific article published on 5 May 2010

IL-23 and Th17 Cells Enhance Th2-Cell–mediated Eosinophilic Airway Inflammation in Mice

scientific article published on 11 September 2008

IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance

article

IL-23 neutralization protects mice from Gram-negative endotoxic shock

scientific article published on 01 May 2006

IL12 in Candida albicans infections.

scientific article published on September 1995

Immune recognition of drug-induced tumor antigens: a study with a nonimmunogenic, revertant clone

scientific article published on 01 September 1992

Immune regulation and tolerance to fungi in the lungs and skin

scientific article published on January 2008

Immunity and tolerance to Aspergillus involve functionally distinct regulatory T cells and tryptophan catabolism

scientific article published in February 2006

Immunogenic tumor variants induced by drug treatment of the L5178Y lymphoma: Search for serologically defined antigens at the clonal level

article

Immunogenicity of tumor peptides: importance of peptide length and stability of peptide/MHC class II complex

scientific article published on 01 July 1999

Immunopharmacology of pyran copolymer ⬇️

scientific article published on June 1, 1978

Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes

scientific article published on 01 July 2007

Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans

scientific article

In vivo natural reactivity of mice against tumor cells

scientific article published on 01 April 1980

Indoleamine 2,3-dioxygenase (IDO) in inflammation and allergy to Aspergillus

scientific article published on 04 June 2008

Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment.

scientific article published on 11 February 2014

Indoleamine 2,3-dioxygenase in infection: the paradox of an evasive strategy that benefits the host

scientific article published on 25 October 2008

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

scientific journal article

Indoleamine 2,3‐dioxygenase: From catalyst to signaling function ⬇️

scientific article published on August 1, 2012

Interleukin-4 and -10 exacerbate candidiasis in mice.

scientific article published in June 1995

Involvement of the Th1 subset of CD4+ T cells in acquired immunity to mouse infection with Trypanosoma equiperdum

scientific article published on 01 September 1992

Lack of Toll IL-1R8 Exacerbates Th17 Cell Responses in Fungal Infection

article

Lack of correlation between DNA-methylating activity and appearance of the immunogenic phenotype in clones of a murine lymphoma treated with mutagens

scientific article (publication date: 1989)

Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells.

scientific article published on 19 September 2005

Ligand binding and functional selectivity of L-tryptophan metabolites at the mouse aryl hydrocarbon receptor (mAhR).

scientific article published on 21 November 2014

Long-term depression of two primary immune responses induced by a single dose of 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC).

scientific article published in June 1978

Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation.

scientific article published on 25 July 2010

Microbiota control of a tryptophan-AhR pathway in disease tolerance to fungi

scientific article

Modulation of circulating colony-stimulating activity in mice: combined effects of IL-1 and bacterial or indomethacin treatment

scientific article published on 01 January 1991

Modulation of colony-stimulating activity by interleukin 1 in mice: opposing effects of combined treatment with indomethacin or prostaglandin E2

scientific article published on 01 May 1992

Modulation of tryptophan catabolism by regulatory T cells.

scientific article published on 26 October 2003

Molecular and genomic aspects of xenogenizing-alkylating drugs

scientific article published on 01 September 1992

NEDD4 controls the expression of GUCD1, a protein upregulated in proliferating liver cells

scientific article

Neutrophils and the adaptive immune response to Candida albicans

scientific article published on October 1996

O 6-Methylguanine-DNA methyltransferase activity and induction of novel immunogenicity in murine tumor cells treated with methylating agents

scientific article published on 01 January 1992

Off-label therapy targeting pathogenic inflammation in COVID-19

scientific article published on 12 June 2020

On the Non-Redundant Roles of TDO2 and IDO1.

scientific article published on 20 October 2014

On watching the watchers: IDO and type I/II IFN

scientific article

Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation

scientific article published on 05 February 2020

Protective immunity induced by low-virulence Candida albicans: cytokine production in the development of the anti-infectious state

scientific article published in December 1989

Protective tolerance to fungi: the role of IL-10 and tryptophan catabolism

scientific article

Receptors and pathways in innate antifungal immunity: the implication for tolerance and immunity to fungi.

scientific article published on January 2007

Regulation of tumor antigen expression by drugs acting as mutagens and/or gene activators

article

Reply to Han et al.: On track for an IDO1-based personalized therapy in autoimmunity

scientific article published on 01 September 2020

Reply to ‘F508del-CFTR is not corrected by thymosin α1’

scientific article published on 01 July 2018

Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

scientific article published on 08 April 2007

Romani & Puccetti reply

scientific article published in Nature

Sensing of mammalian IL-17A regulates fungal adaptation and virulence.

scientific article published on 21 February 2012

Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1.

scientific article published on 17 March 2015

T cell apoptosis by tryptophan catabolism

scientific article published in October 2002

T helper cell dichotomy to Candida albicans: implications for pathology, therapy, and vaccine design.

scientific article published on January 1995

TGF-beta and kynurenines as the key to infectious tolerance

scientific article published on 21 January 2009

Th17/Treg imbalance in murine cystic fibrosis is linked to indoleamine 2,3-dioxygenase deficiency but corrected by kynurenines.

scientific article

The Coevolution of IDO1 and AhR in the Emergence of Regulatory T-Cells in Mammals

scientific article published on 12 February 2015

The cross-talk between opportunistic fungi and the mammalian host via microbiota's metabolism

scientific article

The exploitation of distinct recognition receptors in dendritic cells determines the full range of host immune relationships with Candida albicans

scientific article published in January 2004

Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone.

scientific article

Thymosin 1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance

scientific article published on 01 June 2006

Thymosin alpha1: an endogenous regulator of inflammation, immunity, and tolerance

scientific article published on 10 May 2007

Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis

scientific article

Tolerance, DCs and tryptophan: much ado about IDO

scientific article (publication date: May 2003)

Toll-like receptor 9-mediated induction of the immunosuppressive pathway of tryptophan catabolism.

scientific article

Toward the identification of a tolerogenic signature in IDO-competent dendritic cells.

scientific article published on 8 December 2005

Tryptophan catabolism generates autoimmune-preventive regulatory T cells

scientific article published on 10 October 2006

Tryptophan catabolism in IDO+ plasmacytoid dendritic cells.

scientific article published on April 2007

Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22.

scientific article published in August 2013

Tumor-specific L3T4+ and Lyt-2+ lymphocytes in mice primed to mutagenized cell variants

scientific article published on 01 July 1992

Use of a skin test assay to determine tumor-specific CD8+ T cell reactivity

scientific article published on 01 June 1994

Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells

scientific article published on December 2010

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