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List of works by Matthias P. Müller

2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach

scientific article published on 01 June 2019

A pull-down procedure for the identification of unknown GEFs for small GTPases

scientific article published on 26 February 2016

An Unusual Intramolecular Halogen Bond guides Conformational Selection.

scientific article

Assays for Nucleotide Competitive Reversible and Irreversible Inhibitors of Ras GTPases

scientific article published on 11 June 2018

Augmented Reality in Scientific Publications - Taking the Visualization of 3D Structures to the Next Level

scientific article published on 12 December 2019

Augmented Reality in Scientific Publications-Taking the Visualization of 3D Structures to the Next Level

scientific article published on 01 March 2018

Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA

scientific article published in 2024

Bacterial pathogens commandeer Rab GTPases to establish intracellular niches

scientific article

Cellular model system to dissect the isoform-selectivity of Akt inhibitors

scientific article published on 06 September 2021

Characterization of enzymes from Legionella pneumophila involved in reversible adenylylation of Rab1 protein

scientific article published on 7 August 2012

Efficient Synthesis and Applications of Peptides containing Adenylylated Tyrosine Residues

scientific article published on 25 August 2011

Exploring adenylylation and phosphocholination as post-translational modifications.

scientific article published on 31 October 2013

Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S

scientific article published on 04 October 2019

Locking GTPases covalently in their functional states.

scientific article published on 16 July 2015

Mechanisms of action of Rab proteins, key regulators of intracellular vesicular transport.

scientific article published on 15 November 2016

Molecular control of Rab activity by GEFs, GAPs and GDI.

scientific article published on 5 January 2017

Multivalency in Rab effector interactions.

scientific article published on 27 January 2017

Nucleotide based covalent inhibitors of KRas can only be efficient in vivo if they bind reversibly with GTP-like affinity

scientific article

Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer

scientific article published on 11 March 2019

Reversible phosphocholination of Rab proteins by Legionella pneumophila effector proteins

scientific article published on 3 February 2012

Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt

scientific article published on 13 February 2019

Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae.

scientific article published on 24 April 2018

Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38α MAPK.

scientific article published on 11 September 2017

The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b

scientific article

The versatile Legionella effector protein DrrA.

scientific article published on January 2011

Try Me: Promiscuous Inhibitors Still Allow for Selective Targeted Protein Degradation

scientific article published in January 2018

bMERB domains are bivalent Rab8 family effectors evolved by gene duplication

scientific article published on 23 August 2016

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