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List of works by Anne-Marie Lambeir

A Quantitatiove Desdcription of Microtubule Formadtion in the Presence of Tubulin-Colchicine

scientific article published on 01 May 1983

A kinetic and spectral study of the alkaline transitions of chloroperoxidase

scientific article published on 01 February 1983

A kinetic study of glucagon-like peptide-1 and glucagon-like peptide-2 truncation by dipeptidyl peptidase IV, in vitro

scientific article published on 01 December 2002

A new synthetic method for proline diphenyl phosphonates

A prediction of DPP IV/CD26 domain structure from a physico-chemical investigation of dipeptidyl peptidase IV (CD26) from human seminal plasma

scientific article published on 01 July 1997

A rapid-scan spectrometric and stopped-flow study of compound I and compound II of Pseudomonas cytochrome c peroxidase

scientific article published in February 1985

Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP/prolyl oligopeptidase (PREP)-selectivity

scientific article published on 4 April 2012

Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties

scientific article published on 01 December 2001

Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection.

scientific article

C-terminal clipping of chemokine CCL1/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity

scientific article (publication date: 2012)

Carboxypeptidase M expressed by human bone marrow cells cleaves the C-terminal lysine of stromal cell-derived factor-1alpha: another player in hematopoietic stem/progenitor cell mobilization?

scientific article published on 21 February 2008

Carboxypeptidase M in apoptosis, adipogenesis and cancer

scientific article

Carboxypeptidase M: Multiple alliances and unknown partners.

scientific article published on 17 October 2008

Corrigendum to: Kinetic study of the processing by dipeptidyl-peptidase IV/CD26 of neuropeptides involved in pancreatic insulin secretion (FEBS 25376)

scholarly article published in FEBS Letters

DPP4 inhibitors for diabetes--what next?

scientific article published on 31 July 2008

DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages

scientific article published on 04 February 2019

Demonstration of glycosomes (microbodies) in the bodonid flagellate Trypanoplasma borelli (protozoa, kinetoplastida)

scientific article published on 01 August 1988

Development of irreversible diphenyl phosphonate inhibitors for urokinase plasminogen activator

scientific article published in May 2004

Development of potent and selective dipeptidyl peptidase II inhibitors

article

Dipeptide-derived diphenyl phosphonate esters: mechanism-based inhibitors of dipeptidyl peptidase IV

scientific article published on 01 May 1996

Dipeptidyl Peptidase IV (DPPIV/CD26)-Based Prodrugs of Hydroxy-Containing Drugs

scientific article published on 03 February 2012

Dipeptidyl peptidase 8/9-like activity in human leukocytes

scientific article published on 07 February 2007

Dipeptidyl peptidase 9 (DPP9) from bovine testes: identification and characterization as the short form by mass spectrometry

scientific article

Dipeptidyl peptidase II and leukocyte cell death.

scientific article published on 25 April 2006

Dipeptidyl peptidases and related proteins: multifaceted markers and therapeutic targets

scientific article published in January 2009

Dipeptidyl-peptidase IV and B-type natriuretic peptide. From bench to bedside

scientific article published on January 2009

Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro form

scientific article published on 27 October 2005

Diphenyl phosphonate inhibitors for the urokinase-type plasminogen activator: optimization of the P4 position.

scientific article published in September 2006

Discovery and SAR of Novel and Selective Inhibitors of Urokinase Plasminogen Activator (uPA) with an Imidazo[1,2-a]pyridine Scaffold

article

Dysregulation of the renin-angiotensin system during lung ischemia-reperfusion injury.

scientific article published on 20 July 2016

ECM1 interacts with fibulin-3 and the beta 3 chain of laminin 332 through its serum albumin subdomain-like 2 domain

scientific article

Efficient conversion of tetrapeptide-based TSAO prodrugs to the parent drug by dipeptidyl-peptidase IV (DPPIV/CD26).

scientific article published on August 2007

Enzyme activity and immunohistochemical localization of dipeptidyl peptidase 8 and 9 in male reproductive tissues

scientific article published on 02 February 2009

Expression, purification and preliminary crystallographic analysis of dipeptidyl peptidase IV from Porphyromonas gingivalis

scientific article published on 23 September 2004

Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

article

Fluoro-Olefins as Peptidomimetic Inhibitors of Dipeptidyl Peptidases

scientific article published on 01 March 2005

Functional role of the conserved active site proline of triosephosphate isomerase

scientific article

Gamma-amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors

scientific article

Glucosephosphate isomerase from Trypanosoma brucei. Cloning and characterization of the gene and analysis of the enzyme.

scientific article published on September 1989

Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 1: Substitution of the glycine carboxylic acid group

scientific article published in September 2002

Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 2: substitution of the glycine part

scientific article published in October 2002

Glyceraldehyde-phosphate dehydrogenase from Trypanosoma brucei. Comparison of the glycosomal and cytosolic isoenzymes.

scientific article published in February 1987

High-pressure effect on the equilibrium and kinetics of cyanide binding to chloroperoxidase

scientific article published on 01 October 1983

Importance of biofilm formation and dipeptidyl peptidase IV for the pathogenicity of clinicalPorphyromonas gingivalisisolates

scientific article published on 11 March 2014

In situ prolyl oligopeptidase activity assay in neural cell cultures

article

In vivo effects of a potent, selective DPPII inhibitor: UAMC00039 is a possible tool for the elucidation of the physiological function of DPPII.

scientific article

In vivo inhibition of dipeptidyl peptidase IV activity by pro-pro-diphenyl-phosphonate (Prodipine).

scientific article

In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma

scientific article

Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile).

scientific article published in July 2005

Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay

scientific article

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: identification of dipeptide derived leads

scientific article published on 24 May 2008

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: isoindoline containing inhibitors

scientific article published on 24 May 2008

Irreversible Inhibition of Dipeptidyl Peptidase 8 by Dipeptide-Derived Diaryl Phosphonates

scientific article published on 24 October 2007

Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family

scientific article (publication date: 10 August 2001)

Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7).

scientific article published on March 2005

Kinetic properties of triose-phosphate isomerase from Trypanosoma brucei brucei. A comparison with the rabbit muscle and yeast enzymes

scientific article

Kinetic study of the processing by dipeptidyl-peptidase IV/CD26 of neuropeptides involved in pancreatic insulin secretion.

scientific article

Kinetics of cyanide binding by half-reduced Pseudomonas cytochrome c peroxidase

Kinetics of cyanide binding to chloroperoxidase in the presence of nitrate: detection of the influence of a heme-linked acid group by shift in the appa

article published in 1983

Kinetics of the oxidation of ascorbic acid, ferrocyanide and p-phenolsulfonic acid by chloroperoxidase compounds I and II

scientific article published on 01 February 1987

Kinetics of the reaction of compound II of horseradish peroxidase with hydrogen peroxide to form compound III.

scientific article published in December 1989

Mapping of carboxypeptidase m in normal human kidney and renal cell carcinoma: expression in tumor-associated neovasculature and macrophages

scientific article published on 19 November 2012

Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors

scientific article published on 07 November 2011

Molecular characterization of dipeptidyl peptidase activity in serum

scientific article published on 01 September 2000

On the mechanism of chlorination by chloroperoxidase

scientific article published on 01 January 1987

Optimization and validation of an existing, surgical and robust dry eye rat model for the evaluation of therapeutic compounds

scientific article published on 16 March 2016

Oxygen binding to dithionite-reduced chloroperoxidase

scientific article published on 01 February 1985

P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy

scientific article

Plasma levels of carboxypeptidase U (CPU, CPB2 or TAFIa) are elevated in patients with acute myocardial infarction

scientific article published on 12 November 2015

Preliminary crystallographic studies of glycosomal glyceraldehyde phosphate dehydrogenase from Trypanosoma brucei brucei

scientific article published on 01 April 1987

Presence and release of SR-17 (chromogranin B(586-602)) in the porcine splenic nerve and its enzymatic degradation by CD26/dipeptidyl peptidase IV.

scientific article published in June 2002

Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: the impact of P1-variation

article

Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme

scientific article published on 19 July 2016

Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro

scientific article published on 26 August 2016

Prolyl oligopeptidase stimulates the aggregation of alpha-synuclein

scientific article published on 15 May 2008

Prolylisoxazoles: potent inhibitors of prolyloligopeptidase with antitrypanosomal activity

scientific article published in September 2003

Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 3. Changing metal specificity and the pH profile by site-directed mutagenesis

scientific article published in June 1992

Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes

scientific article published on 01 May 2008

Rapid parallel synthesis of dipeptide diphenyl phosphonate esters as inhibitors of dipeptidyl peptidases

scientific article published in May 2003

Rapid spectral scan and stopped-flow studies of carbon monoxide binding to bovine adrenocortical cytochrome P-450scc

scientific article published on 01 January 1987

Rapid-scan stopped-flow studies of the pH dependence of the reaction between mercuric reductase and NADPH

scientific article published on 01 May 1986

Repositioning the substrate activity screening (SAS) approach as a fragment-based method for identification of weak binders

scientific article

Search for substrates for prolyl oligopeptidase in porcine brain

scientific article published on 5 July 2005

Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold

scientific article

Selective inhibitors of fibroblast activation protein (FAP) with a xanthine scaffold

article

Small, potent, and selective diaryl phosphonate inhibitors for urokinase-type plasminogen activator with in vivo antimetastatic properties

scientific article published in December 2007

Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal?

scientific article

Structure−Activity Relationship of Diaryl Phosphonate Esters as Potent Irreversible Dipeptidyl Peptidase IV Inhibitors

scientific article published on 01 March 1999

Study of the enzymatic degradation of vasostatin I and II and their precursor chromogranin A by dipeptidyl peptidase IV using high-performance liquid chromatography/electrospray mass spectrometry

scientific article published on 01 April 1999

Substrate Activity Screening (SAS) and Related Approaches in Medicinal Chemistry

scientific article published on 4 February 2016

Suggested functions for prolyl oligopeptidase: a puzzling paradox

scientific article published on 10 October 2006

Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines

scientific article published on 17 July 2006

Synthesis and evaluation of azaproline peptides as potential inhibitors of dipeptidyl peptidase IV and prolyl oligopeptidase

Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA)

scientific article published on 27 December 2011

The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis

scientific article (publication date: 2015)

The catalytic cycle of biosynthetic thiolase: a conformational journey of an acetyl group through four binding modes and two oxyanion holes

scientific article

The dipeptidyl peptidase IV (CD26, EC 3.4.14.5) inhibitor vildagliptin is a potent antihyperalgesic in rats by promoting endomorphin-2 generation in the spinal cord

scientific article published on 15 October 2010

The effect of prolyl oligopeptidase inhibition on extracellular acetylcholine and dopamine levels in the rat striatum.

scientific article

The effects of CD26/DPP IV-targeted therapy on acute allograft rejection

scientific article published on 01 February 1997

The first potent diphenyl phosphonate KLK4 inhibitors with unexpected binding kinetics

The formation and decay of the oxyferrous forms of the cytochromes P-450 isolated from Rhizobium japonicum. Rapid spectral scan and stopped flow studies

The importance of the conserved Arg191-Asp227 salt bridge of triosephosphate isomerase for folding, stability, and catalysis

scientific article

The potential of carboxypeptidase M as a therapeutic target in cancer

scientific article published on 07 January 2013

The role of the S1 binding site of carboxypeptidase M in substrate specificity and turn-over

scientific article published on 08 December 2006

Translational research on prolyl oligopeptidase inhibitors: the long road ahead

scientific article published in July 2011

Truncation of macrophage-derived chemokine by CD26/ dipeptidyl-peptidase IV beyond its predicted cleavage site affects chemotactic activity and CC chemokine receptor 4 interaction

scientific article

Use of immobilized adenosine deaminase (EC 3.5.4.4) for the rapid purification of native human CD26/dipeptidyl peptidase IV (EC 3.4.14.5)

scientific article published on 01 January 1996

Validation of a specific prolylcarboxypeptidase activity assay and its suitability for plasma and serum measurements

scientific article published on 10 September 2013

Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases

scientific article (publication date: 21 December 2016)

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