List of works - Mark S. Butler

10-Hydroxydarlingine, a New Tropane Alkaloid from the Australian Proteaceous PlantTriuniaerythrocarpa

article

10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseum

scientific article published in August 2003

5,6,7,3',4',5'-Hexamethoxyflavone from the Australian plant Eremophila debilis (Myoporaceae).

scientific article published in August 2017

A Simple Method for High-Throughput Extract Prefractionation for Biological Screening

article by David R. Appleton et al published 27 June 2007 in Chimia

A benzopyrroloisoquinoline alkaloid from Ficus fistulosa

A fast and straightforward route towards the synthesis of the lissoclimide class of anti-tumour agents

article

A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance

scientific article

A new model for utilising chemical diversity from natural sources

article

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

scientific article

Absolute Configuration and Total Synthesis of a Novel Antimalarial Lipopeptide by the de Novo Preparation of Chiral Nonproteinogenic Amino Acids

scientific article published in 2012

Actephilol A and epiactephilol A: two novel aromatic terpenoids isolated from Actephila excelsa

Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.

scientific article published on 6 January 2016

Adociasulfates 1, 7, and 8: New Bioactive Hexaprenoid Hydroquinones from the Marine Sponge Adocia sp.

scientific article

Agonodepsides a and B: two new depsides from a filamentous fungus F7524.

scientific article published in July 2002

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

scientific article published on 23 June 2020

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

scientific article published on 14 June 2014

Ancisheynine, a novel naphthylisoquinolinium alkaloid from Ancistrocladus heyneanus

article

Anthoptilides A−E, New Briarane Diterpenes from the Australian Sea PenAnthoptilumcf.kukenthali

article

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin

scientific article published on April 2014

Antibacterial Nerol Cinnamates from the Australian Plant Eremophila longifolia

scientific article

Antibiotics in the clinical pipeline at the end of 2015.

scientific article

Antibiotics in the clinical pipeline in 2011 ⬇️

scientific article published on May 18, 2011

Antibiotics in the clinical pipeline in 2013.

scientific article published on 04 September 2013

Antibiotics in the clinical pipeline in October 2019

scientific article published on 10 March 2020

Antineoplastic agents, 326. The stereochemistry of bastadins 8, 10, and 12 from the Bismarck archipelago marine sponge Ianthella basta

scientific article published in May 1995

Ardisiaquinones from Ardisia teysmanniana

scientific article published in December 2001

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

scientific article published on 21 July 2015

Circumdatin G, a new alkaloid from the fungus Aspergillus ochraceus.

scientific article

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

scientific article published on 23 November 2018

Design, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activity

scientific article published on 11 December 2018

Developments in Glycopeptide Antibiotics

scientific article

Discovery of brevijanazines from Aspergillus brevijanus reveals the molecular basis for p-nitrobenzoic acid in fungi

Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans

scientific article published on 17 August 2016

Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads

Dragmacidins: New Protein Phosphatase Inhibitors from a Southern Australian Deep-Water Marine Sponge,Spongosoritessp

article

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

scientific article published on 15 May 2015

Flavonoids from Artocarpus lanceifolius

scientific article published in April 2003

Flemingin-Type Prenylated Chalcones from the Sarawak Rainforest Plant Desmodium congestum

scientific article published on 18 August 2015

Fluorescent Trimethoprim Conjugate Probes To Assess Drug Accumulation in Wild Type and Mutant Escherichia coli

scientific article published on 16 August 2016

Gargantulide A, a complex 52-membered macrolactone showing antibacterial activity from Streptomyces sp.

scientific article published on 27 February 2015

Identification of a naturally occurring quinazolin-4(3H)-one firefly luciferase inhibitor.

scientific article

Identification of aluminium dioxalate in fungal cultures grown on vermiculite

article

Identification of chelerythrine as an inhibitor of BclXL function

scientific article published on 17 April 2003

Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.

scientific article published on 27 September 2016

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

scientific article published on 01 October 2018

Inhibition of the human chemokine receptor CCR5 by variecolin and variecolol and isolation of four new variecolin analogues, emericolins A-D, from Emericella aurantiobrunnea

scientific article published in October 2004

Isolation and Structure of Hemibastadinols 1−3 from the Papua New Guinea Marine SpongeIanthellabasta1

Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2.

scientific article published on 23 January 2013

Isolation and total synthesis of gymnastatin N, a POLO-like kinase 1 active constituent from the fungus Arachniotus punctatus

article by Chee Wee Phoon et al published December 2004 in Tetrahedron

Isolation of Psammaplin A 11‘-Sulfate and Bisaprasin 11‘-Sulfate from the Marine SpongeAplysinellarhax

scientific article published on 01 March 2000

Isolation of xestosterol esters of brominated acetylenic fatty acids from the marine sponge xestospongia testudinaria

scientific article

Microsphaerins A–D, four novel benzophenone dimers with activity against MRSA from the fungus Microsphaeropsis sp

Mucin Binding Reduces Colistin Antimicrobial Activity.

scientific article

NMR spectral assignments of three aspidofractinine alkaloids, kopsine, fruticosine and fruticosamine

scientific article

Natural products as anthelmintics: safeguarding animal health

scientific article published in January 2023

Natural products to drugs: natural product derived compounds in clinical trials

scientific article

Natural products to drugs: natural product-derived compounds in clinical trials

scientific article

Natural products--the future scaffolds for novel antibiotics?

scientific article

Naturally occurring cembranes from an Australian sarcophyton species

scientific article published in August 2002

New estrogenic prenylflavone from Epimedium brevicornum inhibits the growth of breast cancer cells

scientific article

Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis.

scientific article published on 27 April 2016

Octapeptin C4 Induces Less Resistance and Novel Mutations in an Epidemic Carbapenemase-producing Klebsiella pneumoniae ST258 Clinical Isolate Compared to Polymyxins

article by Miranda Pitt et al published 28 April 2018 in bioRxiv

Old dogs and new tricks in antimicrobial discovery.

scientific article published on 2 June 2016

Organic geochemical and geochemical studies of Inner Great Barrier Reef sediments—IV. Identification of terrigenous and marine sourced inputs

Phenolic derivatives from Wigandia urens with weak activity against the chemokine receptor CCR5.

scientific article published in November 2003

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

scientific article published on 2 January 2018

Pyrrole carboxamidine tryptase inhibitors from Leptonychia pubescens

scientific article published in November 2005

Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus

scientific article published on 2 September 2014

Spermine alkaloids from Albizia adinocephala with activity against Plasmodium falciparum plasmepsin II.

scientific article

Structure aided design of chimeric antibiotics

article by Tomislav Karoli et al published April 2012 in Bioorganic & Medicinal Chemistry Letters

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.

scientific article published on 23 January 2018

Structure-Function Studies of Polymyxin B Lipononapeptides

scientific article published on 02 February 2019

Sundaicumones A and B, polyprenylated acylphloroglucinol derivatives from Calophyllumsundaicum with weak activity against the glucocorticoid receptor

scientific article

Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.

scientific article

Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two 'old' antibiotics-polymyxin B and chloramphenicol

scientific article

Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents

scientific article published on 01 June 2015

Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins

Synthesis of Norbornane Bisether Antibiotics via Silver-mediated Alkylation

scientific article published in January 2015

Synthesis of deuterium-labelled analogues of NLRP3 inflammasome inhibitor MCC950.

scientific article published on 26 December 2017

Synthesis of essramycin and comparison of its antibacterial activity

scientific article published on 4 November 2010

Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria.

scientific article published on 12 April 2017

The role of natural product chemistry in drug discovery

scientific article

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

article by James B. McAlpine et al published 13 July 2018 in Natural Product Reports

Three new pyridoacridine type alkaloids from a singaporean ascidian

scientific article published in August 2002

Trivirensols: Selectively Bacteriostatic Sesquiterpene Trimers from the Australian Termite Nest-Derived Fungus Trichoderma virens CMB-TN16

scientific article published on 18 October 2019

List of works by Mark S. Butler

10-Hydroxydarlingine, a New Tropane Alkaloid from the Australian Proteaceous PlantTriuniaerythrocarpa

10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseum

5,6,7,3',4',5'-Hexamethoxyflavone from the Australian plant Eremophila debilis (Myoporaceae).

A Simple Method for High-Throughput Extract Prefractionation for Biological Screening

A benzopyrroloisoquinoline alkaloid from Ficus fistulosa

A fast and straightforward route towards the synthesis of the lissoclimide class of anti-tumour agents

A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance

A new model for utilising chemical diversity from natural sources

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

Absolute Configuration and Total Synthesis of a Novel Antimalarial Lipopeptide by the de Novo Preparation of Chiral Nonproteinogenic Amino Acids

Actephilol A and epiactephilol A: two novel aromatic terpenoids isolated from Actephila excelsa

Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.

Adociasulfates 1, 7, and 8: New Bioactive Hexaprenoid Hydroquinones from the Marine Sponge Adocia sp.

Agonodepsides a and B: two new depsides from a filamentous fungus F7524.

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

Ancisheynine, a novel naphthylisoquinolinium alkaloid from Ancistrocladus heyneanus

Anthoptilides A−E, New Briarane Diterpenes from the Australian Sea PenAnthoptilumcf.kukenthali

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin

Antibacterial Nerol Cinnamates from the Australian Plant Eremophila longifolia

Antibiotics in the clinical pipeline at the end of 2015.

Antibiotics in the clinical pipeline in 2011 ⬇️

Antibiotics in the clinical pipeline in 2013.

Antibiotics in the clinical pipeline in October 2019

Antineoplastic agents, 326. The stereochemistry of bastadins 8, 10, and 12 from the Bismarck archipelago marine sponge Ianthella basta

Ardisiaquinones from Ardisia teysmanniana

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

Circumdatin G, a new alkaloid from the fungus Aspergillus ochraceus.

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

Design, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activity

Developments in Glycopeptide Antibiotics

Discovery of brevijanazines from Aspergillus brevijanus reveals the molecular basis for p-nitrobenzoic acid in fungi

Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans

Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads

Dragmacidins: New Protein Phosphatase Inhibitors from a Southern Australian Deep-Water Marine Sponge,Spongosoritessp

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

Flavonoids from Artocarpus lanceifolius

Flemingin-Type Prenylated Chalcones from the Sarawak Rainforest Plant Desmodium congestum

Fluorescent Trimethoprim Conjugate Probes To Assess Drug Accumulation in Wild Type and Mutant Escherichia coli

Gargantulide A, a complex 52-membered macrolactone showing antibacterial activity from Streptomyces sp.

Identification of a naturally occurring quinazolin-4(3H)-one firefly luciferase inhibitor.

Identification of aluminium dioxalate in fungal cultures grown on vermiculite

Identification of chelerythrine as an inhibitor of BclXL function

Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

Inhibition of the human chemokine receptor CCR5 by variecolin and variecolol and isolation of four new variecolin analogues, emericolins A-D, from Emericella aurantiobrunnea

Isolation and Structure of Hemibastadinols 1−3 from the Papua New Guinea Marine SpongeIanthellabasta1

Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2.

Isolation and total synthesis of gymnastatin N, a POLO-like kinase 1 active constituent from the fungus Arachniotus punctatus

Isolation of Psammaplin A 11‘-Sulfate and Bisaprasin 11‘-Sulfate from the Marine SpongeAplysinellarhax

Isolation of xestosterol esters of brominated acetylenic fatty acids from the marine sponge xestospongia testudinaria

Microsphaerins A–D, four novel benzophenone dimers with activity against MRSA from the fungus Microsphaeropsis sp

Mucin Binding Reduces Colistin Antimicrobial Activity.

NMR spectral assignments of three aspidofractinine alkaloids, kopsine, fruticosine and fruticosamine

Natural products as anthelmintics: safeguarding animal health

Natural products to drugs: natural product derived compounds in clinical trials

Natural products to drugs: natural product-derived compounds in clinical trials

Natural products--the future scaffolds for novel antibiotics?

Naturally occurring cembranes from an Australian sarcophyton species

New estrogenic prenylflavone from Epimedium brevicornum inhibits the growth of breast cancer cells

Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis.

Octapeptin C4 Induces Less Resistance and Novel Mutations in an Epidemic Carbapenemase-producing Klebsiella pneumoniae ST258 Clinical Isolate Compared to Polymyxins

Old dogs and new tricks in antimicrobial discovery.

Organic geochemical and geochemical studies of Inner Great Barrier Reef sediments—IV. Identification of terrigenous and marine sourced inputs

Phenolic derivatives from Wigandia urens with weak activity against the chemokine receptor CCR5.

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

Pyrrole carboxamidine tryptase inhibitors from Leptonychia pubescens

Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus

Spermine alkaloids from Albizia adinocephala with activity against Plasmodium falciparum plasmepsin II.

Structure aided design of chimeric antibiotics

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.

Structure-Function Studies of Polymyxin B Lipononapeptides

Sundaicumones A and B, polyprenylated acylphloroglucinol derivatives from Calophyllumsundaicum with weak activity against the glucocorticoid receptor

Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.

Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two 'old' antibiotics-polymyxin B and chloramphenicol

Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents

Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins

Synthesis of Norbornane Bisether Antibiotics via Silver-mediated Alkylation

Synthesis of deuterium-labelled analogues of NLRP3 inflammasome inhibitor MCC950.