List of works - Johannes Zuegg

A probabilistic measure for alignment-free sequence comparison

scientific article

A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.

scientific article

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

scientific article published on 23 June 2020

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

scientific article published on 14 June 2014

An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics.

scientific article

Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.

scientific article

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

scientific article published on 21 July 2015

Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

scientific article published on 29 April 2016

Crystal structures of the PBP2 glycosyltransferase domain: new opportunities for antibacterial drug design.

scientific article published on October 2007

Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach

scientific article published on 30 March 2015

Drug-likeness and increased hydrophobicity of commercially available compound libraries for drug screening.

scientific article

Helping Chemists Discover New Antibiotics.

scientific article published on 13 May 2015

Identification of antitubercular benzothiazinone compounds by ligand-based design

scientific article published on 31 August 2012

Imperfect coordination chemistry facilitates metal ion release in the Psa permease

scientific article

Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals

scientific article published on 24 March 2017

Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin, and maculatin

scientific article

Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First <i>In Vivo</i> Experiments

scientific article published in 2022

Metal complexes as a promising source for new antibiotics

scientific article published on 12 February 2020

Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites

scientific article published on 18 June 2015

Molecular diversity through sugar scaffolds

scientific article

Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor.

scientific article

Nontoxic Cobalt(III) Schiff Base Complexes with Broad-Spectrum Antifungal Activity

scientific article published on 24 November 2020

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

scientific article published on 31 January 2017

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

scientific article published on 2 January 2018

Small-Molecule Inhibitors of the SOX18 Transcription Factor.

scientific article

Structural model of human IL-13 defines the spatial interactions with the IL-13Ralpha/IL-4Ralpha receptor

scientific article published on 01 August 2001

Structure aided design of chimeric antibiotics

article by Tomislav Karoli et al published April 2012 in Bioorganic & Medicinal Chemistry Letters

Targeting Bacterial Cell Wall Peptidoglycan Synthesis by Inhibition of Glycosyltransferase Activity

scientific article published on 11 September 2015

The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II.

scientific article published in December 2011

Vancomycin: ligand recognition, dimerization and super-complex formation

scientific article

Variation of the net charge, lipophilicity, and side chain flexibility in Dmt(1)-DALDA: Effect on Opioid Activity and Biodistribution

scientific article published on 12 November 2012

List of works by Johannes Zuegg

A probabilistic measure for alignment-free sequence comparison

A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics.

Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

Crystal structures of the PBP2 glycosyltransferase domain: new opportunities for antibacterial drug design.

Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach

Drug-likeness and increased hydrophobicity of commercially available compound libraries for drug screening.

Helping Chemists Discover New Antibiotics.

Identification of antitubercular benzothiazinone compounds by ligand-based design

Imperfect coordination chemistry facilitates metal ion release in the Psa permease

Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals

Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin, and maculatin

Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First <i>In Vivo</i> Experiments

Metal complexes as a promising source for new antibiotics

Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites

Molecular diversity through sugar scaffolds

Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor.

Nontoxic Cobalt(III) Schiff Base Complexes with Broad-Spectrum Antifungal Activity

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

Small-Molecule Inhibitors of the SOX18 Transcription Factor.

Structural model of human IL-13 defines the spatial interactions with the IL-13Ralpha/IL-4Ralpha receptor

Structure aided design of chimeric antibiotics

Targeting Bacterial Cell Wall Peptidoglycan Synthesis by Inhibition of Glycosyltransferase Activity

The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II.

Vancomycin: ligand recognition, dimerization and super-complex formation

Variation of the net charge, lipophilicity, and side chain flexibility in Dmt(1)-DALDA: Effect on Opioid Activity and Biodistribution