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List of works by Michael A. Brockhurst

Adaptive modulation of antibiotic resistance through intragenomic coevolution.

scientific article published on 24 July 2017

Antagonistic coevolution accelerates molecular evolution

scientific article published on 24 February 2010

Antagonistic coevolution across productivity gradients: an experimental test of the effects of dispersal.

scientific article

Antagonistic coevolution with parasites increases the cost of host deleterious mutations

scientific article published on 01 January 2006

Assessing evolutionary risks of resistance for new antimicrobial therapies

scientific article published on 01 April 2019

Bacteria-phage coevolution as a driver of ecological and evolutionary processes in microbial communities

scientific article

Bacteria-virus coevolution.

scientific article published on January 2012

Bacteriophages limit the existence conditions for conjugative plasmids

scientific article published on 2 June 2015

Can We Manipulate the Evolutionary Biology of Pathogens for Clinical Benefit?

scientific article published on 01 August 2018

Character displacement promotes cooperation in bacterial biofilms

scientific article published in October 2006

Coevolution can explain defensive secondary metabolite diversity in plants

scientific article

Coevolving parasites enhance the diversity-decreasing effect of dispersal.

scientific article published on 16 February 2011

Comparison of Independent Evolutionary Origins Reveals Both Convergence and Divergence in the Metabolic Mechanisms of Symbiosis

scientific article published on 02 January 2020

Conflicting selection alters the trajectory of molecular evolution in a tripartite bacteria-plasmid-phage interaction.

scientific article published on March 2017

Conjugation is necessary for a bacterial plasmid to survive under protozoan predation

scientific article published on February 2016

Cooperation peaks at intermediate disturbance

scientific article published on 22 March 2007

Cross-resistance is modular in bacteria-phage interactions

article

Defining the functional traits that drive bacterial decomposer community productivity.

scientific article

Differential impact of simultaneous migration on coevolving hosts and parasites

scientific article

Differential infection properties of three inducible prophages from an epidemic strain of Pseudomonas aeruginosa.

scientific article

Dispersal and natural enemies interact to drive spatial synchrony and decrease stability in patchy populations

scientific article published on 31 August 2009

Divergent, coexisting Pseudomonas aeruginosa lineages in chronic cystic fibrosis lung infections

scientific article published on April 2015

Diversity and productivity peak at intermediate dispersal rate in evolving metacommunities.

scientific article

Ecological and Evolutionary Benefits of Temperate Phage: What Does or Doesn't Kill You Makes You Stronger.

scientific article published on 6 October 2017

Ecological drivers of the evolution of public-goods cooperation in bacteria.

scientific article published in February 2010

Ecology: death and destruction determine diversity

scientific article

Editorial overview: viral evolution: exploring the frontiers of virus evolution in the lab, the field and the clinic

scientific article published on 13 September 2014

Environmentally co-occurring mercury resistance plasmids are genetically and phenotypically diverse and confer variable context-dependent fitness effects

scientific article published on 13 May 2015

Epistatic interactions alter dynamics of multilocus gene-for-gene coevolution

scientific article

Evidence that intraspecific trait variation among nasal bacteria shapes the distribution of Staphylococcus aureus

scientific article

Evolution. Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system

scientific article published in February 2015

Evolution. Sex, death, and the Red Queen

scientific article published in July 2011

Evolutionary diversification of Pseudomonas aeruginosa in an artificial sputum model

scientific article

Evolutionary rescue can be impeded by temporary environmental amelioration

scientific article published on 25 June 2015

Experimental adaptation to high and low quality environments under different scales of temporal variation.

scientific article published in January 2007

Experimental coevolution of species interactions ⬇️

scientific article published on March 20, 2013

Experimental coevolution with bacteria and phage. The Pseudomonas fluorescens--Phi2 model system

scientific article published on 26 January 2007

Experimental evolution can unravel the complex causes of natural selection in clinical infections

scientific article

Experimental evolution of local adaptation under unidimensional and multidimensional selection

scientific article published in 2022

Extremely fast amelioration of plasmid fitness costs by multiple functionally diverse pathways

scientific article published on 01 January 2020

First steps in experimental cancer evolution.

scientific article published on 3 January 2013

Gene mobility promotes the spread of resistance in bacterial populations

scientific article published on 31 March 2017

High virulence sub-populations in Pseudomonas aeruginosa long-term cystic fibrosis airway infections

scientific article

Host control and nutrient trading in a photosynthetic symbiosis.

scientific article published on 26 February 2016

How does spatial dispersal network affect the evolution of parasite local adaptation?

scientific article

Hybridization facilitates evolutionary rescue

scientific article

Hybridization in Parasites: Consequences for Adaptive Evolution, Pathogenesis, and Public Health in a Changing World

scientific article

Limited and Strain-Specific Transcriptional and Growth Responses to Acquisition of a Multidrug Resistance Plasmid in Genetically Diverse Escherichia coli Lineages

scientific article published in 2021

Lytic activity by temperate phages of Pseudomonas aeruginosa in long-term cystic fibrosis chronic lung infections

scientific article

Metabolic constraints for a novel symbiosis

scientific article

Migration promotes plasmid stability under spatially heterogeneous positive selection

scientific article published on 01 May 2018

Mobile Compensatory Mutations Promote Plasmid Survival

scientific article published on 15 January 2019

Multi-host environments select for host-generalist conjugative plasmids

scientific article

Negative frequency-dependent selection is intensified at higher population densities in protist populations.

scientific article

Next-generation sequencing as a tool to study microbial evolution.

scientific article published on 27 September 2010

Niche occupation limits adaptive radiation in experimental microcosms

scientific article

Parallel compensatory evolution stabilizes plasmids across the parasitism-mutualism continuum.

scientific article

Plasmid carriage can limit bacteria-phage coevolution.

scientific article published on August 2015

Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation

scientific article published on 13 October 2021

Plasmid stability is enhanced by higher-frequency pulses of positive selection.

scientific article

Plasmid-mediated horizontal gene transfer is a coevolutionary process

scientific article published on 5 May 2012

Population bottlenecks promote cooperation in bacterial biofilms

scientific article

Positive selection inhibits gene mobilisation and transfer in soil bacterial communities.

scientific article published on 31 July 2017

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections

scientific article

Pseudomonas aeruginosa population diversity and turnover in cystic fibrosis chronic infections

scientific article published on 4 February 2011

RAMP resistance

scientific article published in Nature

Rapid compensatory evolution promotes the survival of conjugative plasmids.

scientific article published on 4 May 2016

Rapid evolution of microbe-mediated protection against pathogens in a worm host

scientific article published on 15 March 2016

Rapidly fluctuating environments constrain coevolutionary arms races by impeding selective sweeps

scientific article published on 12 June 2013

Refined analyses suggest that recombination is a minor source of genomic diversity in Pseudomonas aeruginosa chronic cystic fibrosis infections

scientific article

Resistance Evolution against Phage Combinations Depends on the Timing and Order of Exposure

scientific article published on 24 September 2019

Resource supply and the evolution of public-goods cooperation in bacteria

scientific article

Running with the Red Queen: the role of biotic conflicts in evolution

scientific article

Sampling the mobile gene pool: innovation via horizontal gene transfer in bacteria

scientific article published in December 2017

Selective Conditions for a Multidrug Resistance Plasmid Depend on the Sociality of Antibiotic Resistance.

scientific article published on 19 January 2016

Shining a Light on Exploitative Host Control in a Photosynthetic Endosymbiosis.

scientific article published on 29 December 2015

Social evolution: slimy cheats pay a price.

scientific article published in May 2015

Source Populations Act as Coevolutionary Pacemakers in Experimental Selection Mosaics Containing Hotspots and Coldspots

scientific article published on 01 May 2009

Source-sink plasmid transfer dynamics maintain gene mobility in soil bacterial communities.

scientific article published on 06 July 2016

Spatial heterogeneity and the stability of host-parasite coexistence.

scientific article

Sub-inhibitory concentrations of some antibiotics can drive diversification of Pseudomonas aeruginosa populations in artificial sputum medium

scientific article

THE EVOLUTION OF SPECIFICITY IN EVOLVING AND COEVOLVING ANTAGONISTIC INTERACTIONS BETWEEN A BACTERIA AND ITS PHAGE

scientific article published on 12 November 2007

THE IMPACT OF MIGRATION FROM PARASITE-FREE PATCHES ON ANTAGONISTIC HOST-PARASITE COEVOLUTION

scientific article published on 01 May 2007

TWO-STEP INFECTION PROCESSES CAN LEAD TO COEVOLUTION BETWEEN FUNCTIONALLY INDEPENDENT INFECTION AND RESISTANCE PATHWAYS

scientific article published on 23 February 2012

Temperate Bacteriophages from Chronic Pseudomonas aeruginosa Lung Infections Show Disease-Specific Changes in Host Range and Modulate Antimicrobial Susceptibility

scientific article published on 04 June 2019

Temperate phages both mediate and drive adaptive evolution in pathogen biofilms

scientific article published on 05 July 2016

Temperate phages enhance pathogen fitness in chronic lung infection

scientific article published on 12 April 2016

Temporal dynamics of bacteria-plasmid coevolution under antibiotic selection

scientific article published on 12 September 2018

The Ecology and Evolution of Pangenomes

scientific article published on 01 October 2019

The effect of a bacteriophage on diversification of the opportunistic bacterial pathogen, Pseudomonas aeruginosa

scientific article

The effect of hybrid transgression on environmental tolerance in experimental yeast crosses.

scientific article published on 28 September 2014

The effect of spatial heterogeneity and parasites on the evolution of host diversity

scientific article

The effects of spatial structure, frequency dependence and resistance evolution on the dynamics of toxin-mediated microbial invasions ⬇️

scientific article published on 16 July 2015

The evolution and genetics of virus host shifts

scientific article

The evolution of host-parasite range.

scientific article

The evolution of plasmid stability: Are infectious transmission and compensatory evolution competing evolutionary trajectories?

scientific article published on 28 April 2017

The impact of parasite dispersal on antagonistic host-parasite coevolution

scientific article published on 08 July 2008

The impact of phages on interspecific competition in experimental populations of bacteria

scientific article

The interactive effects of parasites, disturbance, and productivity on experimental adaptive radiations

scientific article published on 26 November 2007

The role of exploitation in the establishment of mutualistic microbial symbioses

scientific article published on 01 June 2019

Therapeutic antimicrobial peptides may compromise natural immunity ⬇️

scientific article published on 25 January 2012

Transmission and lineage displacement drive rapid population genomic flux in cystic fibrosis airway infections of a Pseudomonas aeruginosa epidemic strain.

scientific article

Transposable temperate phages promote the evolution of divergent social strategies in Pseudomonas aeruginosa populations

scientific article published on 09 October 2019

Variable plasmid fitness effects and mobile genetic element dynamics across Pseudomonas species

scientific article

Variation and asymmetry in host-symbiont dependence in a microbial symbiosis.

scientific article published on 9 July 2018

Variation in Streptococcus pneumoniae susceptibility to human antimicrobial peptides may mediate intraspecific competition

article

Viral host-adaptation: insights from evolution experiments with phages ⬇️

scientific article published on July 25, 2013

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