List of works - Mark L. Smythe

A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1†,§

scientific article published on 01 April 1999

A gradient descent algorithm for minimizing amino acid coupling reactions when synthesizing cyclic-peptide libraries.

scientific article published in August 2006

A safety catch linker for Fmoc-based assembly of constrained cyclic peptides.

scientific article published in September 2005

A subset-orientated algorithm for minimizing the number of steps required for synthesis of cyclic-peptide libraries

scientific article published in January 2002

A versatile synthetic approach to peptidyl privileged structures using a "safety-catch" linker.

scientific article

An activated O --> N acyl transfer auxiliary: efficient amide-backbone substitution of hindered "difficult" peptides

scientific article published in September 2000

Conformational searching using a population-based incremental learning algorithm

scientific article published in February 2011

Cyclic tetrapeptides via the ring contraction strategy: chemical techniques useful for their identification.

scientific article

Defining scaffold geometries for interacting with proteins: geometrical classification of secondary structure linking regions

scientific article published on 23 September 2010

Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases.

scientific article published on August 2010

Development of small molecules that mimic the binding of omega-conotoxins at the N-type voltage-gated calcium channel

scientific article published in January 2004

Difficult Macrocyclizations: New Strategies for Synthesizing Highly Strained Cyclic Tetrapeptides

scientific article published on 01 July 2003

Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo

scientific article published on 10 November 2015

Exploring privileged structures: the combinatorial synthesis of cyclic peptides

scientific article published on 01 January 2002

Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase

scientific article

Increased site 1 affinity improves biopotency of porcine growth hormone. Evidence against diffusion dependent receptor dimerization

scientific article

Intramolecular disulphide bond arrangements in nonhomologous proteins

scientific article published on February 2005

Library of biphenyl privileged substructures using a safety-catch linker approach.

scientific article

Proteolysis of human hemoglobin by schistosome cathepsin D.

scientific article

Proteolytic degradation of host hemoglobin by schistosomes.

scientific article published on October 1997

Sigma-class glutathione transferases.

scientific article published on 22 March 2011

The combinatorial synthesis of bicyclic privileged structures or privileged substructures.

scientific article

The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptides.

scientific article

Topological side-chain classification of beta-turns: ideal motifs for peptidomimetic development.

scientific article published in August 2005

List of works by Mark L. Smythe

A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1†,§

A gradient descent algorithm for minimizing amino acid coupling reactions when synthesizing cyclic-peptide libraries.

A safety catch linker for Fmoc-based assembly of constrained cyclic peptides.

A subset-orientated algorithm for minimizing the number of steps required for synthesis of cyclic-peptide libraries

A versatile synthetic approach to peptidyl privileged structures using a "safety-catch" linker.

An activated O --> N acyl transfer auxiliary: efficient amide-backbone substitution of hindered "difficult" peptides

Conformational searching using a population-based incremental learning algorithm

Cyclic tetrapeptides via the ring contraction strategy: chemical techniques useful for their identification.

Defining scaffold geometries for interacting with proteins: geometrical classification of secondary structure linking regions

Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases.

Development of small molecules that mimic the binding of omega-conotoxins at the N-type voltage-gated calcium channel

Difficult Macrocyclizations: New Strategies for Synthesizing Highly Strained Cyclic Tetrapeptides

Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo

Exploring privileged structures: the combinatorial synthesis of cyclic peptides

Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase

Increased site 1 affinity improves biopotency of porcine growth hormone. Evidence against diffusion dependent receptor dimerization

Intramolecular disulphide bond arrangements in nonhomologous proteins

Library of biphenyl privileged substructures using a safety-catch linker approach.

Proteolysis of human hemoglobin by schistosome cathepsin D.

Proteolytic degradation of host hemoglobin by schistosomes.

Sigma-class glutathione transferases.

The combinatorial synthesis of bicyclic privileged structures or privileged substructures.

The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptides.

Topological side-chain classification of beta-turns: ideal motifs for peptidomimetic development.