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List of works by Bruce A. Vallance

A novel mouse model of Campylobacter jejuni gastroenteritis reveals key pro-inflammatory and tissue protective roles for Toll-like receptor signaling during infection

scientific article

A novel secretion pathway of Salmonella enterica acts as an antivirulence modulator during salmonellosis

scientific article

Absence of stearoyl-CoA desaturase-1 does not promote DSS-induced acute colitis.

scientific article published on 17 August 2009

Active vitamin D (1,25-dihydroxyvitamin D3) increases host susceptibility to Citrobacter rodentium by suppressing mucosal Th17 responses

scientific article

Aggregation via the red, dry, and rough morphotype is not a virulence adaptation in Salmonella enterica serovar Typhimurium.

scientific article

Antibiotic treatment alters the colonic mucus layer and predisposes the host to exacerbated Citrobacter rodentium-induced colitis.

scientific article

Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria

article

Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-κB and p38 mitogen-activated protein kinase activation.

scientific article

Bacterial stimulation of the TLR-MyD88 pathway modulates the homeostatic expression of ileal Paneth cell α-defensins.

scientific article

CD4+ T cells drive goblet cell depletion during Citrobacter rodentium infection

scientific article published on 7 October 2013

Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis

scientific article published on 9 January 2008

Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: role of mitochondrial associated protein (Map).

scientific article published on 7 June 2006

Citrobacter rodentium infection induces MyD88-dependent formation of ubiquitinated protein aggregates in the intestinal epithelium.

scientific article published on 20 October 2010

Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice

scientific article published in April 2003

Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies.

scientific article

Cloning vectors and fluorescent proteins can significantly inhibit Salmonella enterica virulence in both epithelial cells and macrophages: implications for bacterial pathogenesis studies.

scientific article

Colonic microbiota alters host susceptibility to infectious colitis by modulating inflammation, redox status, and ion transporter gene expression

scientific article

Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

scientific article published on 11 March 2010

Critical role for signal transducer and activator of transcription factor 6 in mediating intestinal muscle hypercontractility and worm expulsion in Trichinella spiralis-infected mice

scientific article

Cutting Edge: Intestinal Mucus Limits the Clonal Deletion of Developing T Cells Specific for an Oral Antigen

scientific article published on 15 June 2020

Dissemination of invasive Salmonella via bacterial-induced extrusion of mucosal epithelia.

scientific article

Enteropathogenic Escherichia coli infection induces expression of the early growth response factor by activating mitogen-activated protein kinase cascades in epithelial cells.

scientific article published on October 2001

Epithelial p38alpha controls immune cell recruitment in the colonic mucosa.

scientific article

EspF is crucial for Citrobacter rodentium-induced tight junction disruption and lethality in immunocompromised animals

scientific article published on 28 June 2019

Flagellin-dependent and -independent inflammatory responses following infection by enteropathogenic Escherichia coli and Citrobacter rodentium

scientific article

Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice

scientific article published on 13 December 2009

Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium

scientific article

IL-4 gene transfer to the small bowel serosa leads to intestinal inflammation and smooth muscle hyperresponsiveness.

scientific article published in January 2007

Indispensable functions of ABL and PDGF receptor kinases in epithelial adherence of attaching/effacing pathogens under physiological conditions.

scientific article

Innate host responses to enteric bacterial pathogens: a balancing act between resistance and tolerance.

scientific article published on 15 February 2012

Interleukin-11 reduces TLR4-induced colitis in TLR2-deficient mice and restores intestinal STAT3 signaling.

scientific article published on 25 June 2010

Interleukin-5 deficient mice exhibit impaired host defence against challenge Trichinella spiralis infections

scientific article published on 01 October 2000

Intestinal epithelium-specific MyD88 signaling impacts host susceptibility to infectious colitis by promoting protective goblet cell and antimicrobial responses.

scientific article published on 23 June 2014

Intestinal microbiota are transiently altered during Salmonella-induced gastroenteritis

scientific article published in August 2008

Intestinal restriction of Salmonella Typhimurium requires caspase-1 and caspase-11 epithelial intrinsic inflammasomes

scientific article published on 13 April 2020

Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection

scientific article published on 31 March 2021

Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.

scientific article published on 21 April 2010

Modulation of host cytoskeleton function by the enteropathogenic Escherichia coli and Citrobacter rodentium effector protein EspG

scientific article

Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa

scientific article

MyD88 signaling promotes both mucosal homeostatic and fibrotic responses during Salmonella-induced colitis

scientific article published on 7 June 2012

MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis

scientific article published on 02 November 2007

Myenteric plexus injury and apoptosis in experimental colitis.

scientific article published in January 2005

Noradrenergic and cholinergic neural pathways mediate stress-induced reactivation of colitis in the rat.

scientific article published in January 2006

Nramp1 drives an accelerated inflammatory response during Salmonella-induced colitis in mice

scientific article published on 3 November 2008

Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection.

scientific article

Persistent intestinal neuromuscular dysfunction after acute nematode infection in mice

scientific article published on 01 October 1997

Prebiotic Enriched Exclusive Enteral Nutrition Suppresses Colitis via Gut Microbiome Modulation and Expansion of Anti-inflammatory T Cells in a Mouse Model of Colitis

scientific article published on 29 June 2021

Putative inflammatory and immunological mechanisms in functional bowel disorders

scientific article published on 01 October 1999

Regulated virulence controls the ability of a pathogen to compete with the gut microbiota.

scientific article

Relative contributions of NOS isoforms during experimental colitis: endothelial-derived NOS maintains mucosal integrity

scientific article

Requirement of epithelial integrin-linked kinase for facilitation of Citrobacter rodentium-induced colitis.

scientific article

Role of M-CSF-dependent macrophages in colitis is driven by the nature of the inflammatory stimulus

scientific article

Saccharomyces boulardii ameliorates Citrobacter rodentium-induced colitis through actions on bacterial virulence factors.

scientific article published on 21 November 2007

Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis

scientific article published on June 2005

Salmonella infection of gallbladder epithelial cells drives local inflammation and injury in a model of acute typhoid fever.

scientific article published on December 2009

Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine

scientific article

Salmonella type III effectors PipB and PipB2 are targeted to detergent-resistant microdomains on internal host cell membranes

scientific article published in August 2003

Severe COVID-19 Infection and Pediatric Comorbidities: A Systematic Review and Meta-Analysis

scientific article published on 20 November 2020

SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells

scientific journal article

SseA is required for translocation of Salmonella pathogenicity island-2 effectors into host cells

scientific article published on June 2003

SseK1 and SseK2 are novel translocated proteins of Salmonella enterica serovar typhimurium.

scientific article published on September 2004

T cell–mediated exocrine pancreatic damage in major histocompatibility complex class II–deficient mice

scientific article published on 01 October 1998

TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen

scientific article

TGF-beta1 gene transfer to the mouse colon leads to intestinal fibrosis

scientific article

TLR9 limits enteric antimicrobial responses and promotes microbiota-based colonisation resistance during Citrobacter rodentium infection

scientific article published on 07 May 2019

The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis.

scientific article

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease.

scientific article published on 4 February 2007

The effect of nematode infection upon intestinal smooth muscle function

scientific article published on 01 May 1998

The role of CD4+ lymphocytes in the susceptibility of mice to stress-induced reactivation of experimental colitis

scientific article published on 01 October 1999

The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells

scientific article

Toll-like receptor 2 plays a critical role in maintaining mucosal integrity during Citrobacter rodentium-induced colitis

scientific article published on 02 October 2007

Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice.

scientific article

Vasoactive intestinal peptide ameliorates intestinal barrier disruption associated with Citrobacter rodentium-induced colitis

scientific article published on 6 August 2009

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