List of works by David O. Bates

3D reconstruction of the glycocalyx structure in mammalian capillaries using electron tomography

scientific article

A TRPC-like non-selective cation current activated by alpha 1-adrenoceptors in rat mesenteric artery smooth muscle cells

scientific article published on 11 May 2006

A human neutralizing antibody specific to Ang-2 inhibits ocular angiogenesis.

scientific article

A role for the endothelial glycocalyx in regulating microvascular permeability in diabetes mellitus.

scientific article published on January 2007

Activation of Notch signaling by soluble Dll4 decreases vascular permeability via a cAMP/PKA-dependent pathway

scientific article published on 25 January 2019

Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma

scientific article published on 9 March 2016

Alternative Splicing Events and Their Clinical Significance in Colorectal Cancer: Targeted Therapeutic Opportunities

scientific article published in 2023

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

scientific article

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

scientific article published on 19 February 2019

An adenovirus-mediated gene-transfer model of angiogenesis in rat mesentery

scientific article published in June 2004

An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease

scientific article

An interstitial hypothesis for breast cancer related lymphoedema

scientific article

An unexpected tail of VEGF and PlGF in pre-eclampsia

scientific article

Antiangiogenic actions of vascular endothelial growth factor-A165b, an inhibitory isoform of vascular endothelial growth factor-A, in human obesity

scientific article

Arteriolar genesis and angiogenesis induced by endothelial nitric oxide synthase overexpression results in a mature vasculature.

scientific article published on 22 May 2008

BDNF (Brain-Derived Neurotrophic Factor) Promotes Embryonic Stem Cells Differentiation to Endothelial Cells Via a Molecular Pathway, Including MicroRNA-214, EZH2 (Enhancer of Zeste Homolog 2), and eNOS (Endothelial Nitric Oxide Synthase)

scientific article published on 01 September 2018

Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms

scientific article

Can the co-dependence of the immune system and angiogenesis facilitate pharmacological targeting of tumours?

scientific article

Chemokine-mediated migration of melanoma cells towards lymphatics--a mechanism contributing to metastasis

scientific article published on 27 November 2006

Chemotrap-1: an engineered soluble receptor that blocks chemokine-induced migration of metastatic cancer cells in vivo

scientific article published on 24 August 2010

Circulating levels of anti-angiogenic VEGF-A isoform (VEGF-Axxxb) in colorectal cancer patients predicts tumour VEGF-A ratios

scientific article published on 15 May 2015

Consensus guidelines for the use and interpretation of angiogenesis assays

article

Correction: LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.

scientific article published on May 2017

Critical role of tissue kallikrein in vessel formation and maturation: implications for therapeutic revascularization.

scientific article

Cytosolic Ca2+ concentration and rate of increase of the cytosolic Ca2+ concentration in the regulation of vascular permeability in Rana in vivo

scientific article published on 17 February 2005

Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.

scientific article

Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain

scientific article published on 11 July 2018

Diabetic retinopathy is associated with a switch in splicing from anti- to pro-angiogenic isoforms of vascular endothelial growth factor.

scientific article

Differential Expression of VEGF-Axxx Isoforms Is Critical for Development of Pulmonary Fibrosis

scientific article

Differential effects of vascular endothelial growth factor-C and placental growth factor-1 on the hydraulic conductivity of frog mesenteric capillaries

scientific article published in March 2001

Differential regulation of blood flow-induced neovascularization and mural cell recruitment by vascular endothelial growth factor and angiopoietin signalling.

scientific article published on 21 November 2016

Direct detection and measurement of wall shear stress using a filamentous bio-nanoparticle

scientific article

Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF).

scientific article

Enhanced notch signaling modulates unproductive revascularization in response to nitric oxide-angiopoietin signaling in a mouse model of peripheral ischemia

scientific article published on 19 June 2019

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors

scientific article published in October 2008

Failure to up-regulate VEGF165b in maternal plasma is a first trimester predictive marker for pre-eclampsia

scientific article published on February 2009

Functional distinctions in cytosolic calcium regulation between cells of the glomerular filtration barrier

scientific article published on July 2010

Glomerular filtration barrier and molecular segregation: guilty as charged?

scientific article published on 11 November 2010

Glomerular filtration into the subpodocyte space is highly restricted under physiological perfusion conditions.

scientific article published on 22 August 2007

Hallmarks of alternative splicing in cancer

scientific article published on 16 December 2013

Human uremic plasma increases microvascular permeability to water and proteins in vivo

scientific article published on 01 April 2002

IL-10 regulation of macrophage VEGF production is dependent on macrophage polarisation and hypoxia

scientific article published on 4 June 2010

IL-4 regulates specific Arg-1(+) macrophage sFlt-1-mediated inhibition of angiogenesis.

scientific article published on 13 June 2015

Impaired vascular permeability regulation caused by the VEGF₁₆₅b splice variant in pre-eclampsia.

scientific article

In vivo mechanisms of vascular endothelial growth factor-mediated increased hydraulic conductivity of Rana capillaries

scientific article

Incorrect citation

scientific article published on 21 June 2011

LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma

scientific article

Loss of the endothelial glycocalyx links albuminuria and vascular dysfunction.

scientific article

Lymphoedema in urological cancer.

scientific article published on January 2004

Mammary alveolar development during lactation is inhibited by the endogenous antiangiogenic growth factor isoform, VEGF165b

scientific article published on 21 November 2007

Measurement of Angiogenesis, Arteriolargenesis, and Lymphangiogenesis Phenotypes by Use of Two-Dimensional Mesenteric Angiogenesis Assay

scientific article

Measurement of angiogenic phenotype by use of two-dimensional mesenteric angiogenesis assay

scientific article published on January 2009

Measurement of hydraulic conductivity of single perfused Rana mesenteric microvessels between periods of controlled shear stress

scientific article published on 01 September 2002

Mechanisms regulating angiogenesis underlie seasonal control of pituitary function.

scientific article published on 7 March 2017

Medication Use for Childhood Pneumonia at a Children's Hospital in Shanghai, China: Analysis of Pattern Mining Algorithms

article

Models of Oxygen Induced Retinopathy in Rodents.

scientific article published in January 2016

Molecular diversity of VEGF-A as a regulator of its biological activity.

scientific article

Neurotrophin-3 is a novel angiogenic factor capable of therapeutic neovascularization in a mouse model of limb ischemia.

scientific article

New prospects in the roles of the C-terminal domains of VEGF-A and their cooperation for ligand binding, cellular signaling and vessels formation.

scientific article

Novel hemodynamic structures in the human glomerulus

scientific article published on 20 June 2018

Novel insight into the pathophysiology of breast-cancer-related lymphoedema

scientific article published on 01 August 2001

Novel mechanisms of resistance to vemurafenib in melanoma - V600E B-Raf reversion and switching VEGF-A splice isoform expression

scientific article published on 15 December 2014

Ovarian VEGF(165)b expression regulates follicular development, corpus luteum function and fertility

scientific article published on 9 January 2012

Overexpression of VEGF165b in podocytes reduces glomerular permeability.

scientific article

Pharmacology of Modulators of Alternative Splicing

scientific article published on January 2017

Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators

scientific article published on 18 June 2018

Plasma from women with severe pre-eclampsia increases microvascular permeability in an animal model in vivo

scientific article published on 01 October 2004

Pre-eclampsia and the microcirculation: a novel explanation

scientific article published in April 2003

Prediction of melanoma metastasis by the Shields index based on lymphatic vessel density

scientific article

Recombinant human VEGF165b inhibits experimental choroidal neovascularization

scientific article

Recombinant human VEGF165b protein is an effective anti-cancer agent in mice.

scientific article published on 24 July 2008

Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia.

scientific article published on 21 August 2014

Regulation of human feto-placental endothelial barrier integrity by vascular endothelial growth factors: competitive interplay between VEGF-A165a, VEGF-A165b, PIGF and VE-cadherin

scientific article

Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis

scientific journal article

Regulation of vascular endothelial growth factor in prostate cancer.

scientific article published on 13 April 2015

Regulation of vascular permeability by vascular endothelial growth factors.

scientific article

Resolution of the three dimensional structure of components of the glomerular filtration barrier

scientific article

SRPK1 inhibition in vivo: modulation of VEGF splicing and potential treatment for multiple diseases.

scientific article published on August 2012

SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity

scientific article published on 27 August 2013

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

scientific article published in Nature Communications

Sensory neuronal sensitisation occurs through HMGB-1-RAGE and TRPV1 in high-glucose conditions

scientific article published on 26 July 2018

Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer

scientific article

Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function

scientific article published on 19 May 2017

South African Herbal Extracts as Potential Chemopreventive Agents: Screening for Anticancer Splicing Activity

scientific article published on January 2016

Splicing Factor Polymorphisms, the Control of VEGF Isoforms and Association with Angiogenic Eye Disease

scientific article published on 10 February 2011

Starling pressures in the human arm and their alteration in postmastectomy oedema

scientific article published on 01 June 1994

Sulfated Galactans from Red Seaweed Gracilaria fisheri Target EGFR and Inhibit Cholangiocarcinoma Cell Proliferation

scientific article published on 6 April 2017

Sulfated galactans from the red seaweed Gracilaria fisheri exerts anti-migration effect on cholangiocarcinoma cells

scientific article

TNF-α-induced ICAM-1 expression and monocyte adhesion in human RPE cells is mediated in part through autocrine VEGF stimulation

scientific article

Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma

scientific article

The VEGF-A exon 8 splicing-sensitive fluorescent reporter mouse is a novel tool to assess the effects of splicing regulatory compounds in vivo

scientific article published on 21 August 2019

The alternatively spliced anti-angiogenic family of VEGF isoforms VEGFxxxb in human kidney development

scientific article published on 27 November 2008

The anti-angiogenic VEGF isoform VEGF165b transiently increases hydraulic conductivity, probably through VEGF receptor 1 in vivo

scientific article published on 19 January 2006

The carboxyl terminus of VEGF-A is a potential target for anti-angiogenic therapy

scientific article

The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain.

scientific article published on 8 September 2016

The endogenous anti-angiogenic VEGF isoform, VEGF165b inhibits human tumour growth in mice.

scientific article published on 18 March 2008

The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term

scientific article published on 01 May 2006

The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1.

scientific article

The role of VEGF-A165b in trophoblast survival.

scientific article

The role of endothelial cell Ca2+ store release in the regulation of microvascular permeability in vivo

scientific article

Therapeutic potential of inhibitory VEGF splice variants.

scientific article

Therapeutic potential of manipulating VEGF splice isoforms in oncology

scientific article

Three-dimensional reconstruction of glomeruli by electron microscopy reveals a distinct restrictive urinary subpodocyte space

scientific article published on 13 April 2005

Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD

scientific article published on 05 September 2013

Transient osmotic absorption of fluid in microvessels exposed to low concentrations of dimethyl sulfoxide.

scientific article published in January 2006

VEGF 165 b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy.

scientific article

VEGF activates receptor-operated cation channels in human microvascular endothelial cells.

scientific article published on 8 June 2006

VEGF and Angiopoietin-1 Stimulate Different Angiogenic Phenotypes That Combine to Enhance Functional Neovascularization in Adult Tissue

VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo

scientific article published on 25 August 2009

VEGF-A165 b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney.

scientific article published on 2 June 2017

VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro.

scientific article published on 06 July 2013

VEGF-A165b is cytoprotective and antiangiogenic in the retina

scientific article

VEGF-C induced angiogenesis preferentially occurs at a distance from lymphangiogenesis.

scientific article published on 07 December 2007

VEGF-mediated elevated intracellular calcium and angiogenesis in human microvascular endothelial cells in vitro are inhibited by dominant negative TRPC6.

scientific article published on October 2008

VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy

scientific article published on 02 November 2018

VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis

scientific article published on 14 March 2018

Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy

scientific article

Vascular Endothelial Growth Factor-A165b Restores Normal Glomerular Water Permeability in a Diphtheria-Toxin Mouse Model of Glomerular Injury.

scientific article published on 26 January 2018

Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity

scientific article published in June 2008

Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs

scientific article published on 03 May 2007

Vascular endothelial growth factor increases Rana vascular permeability and compliance by different signalling pathways

scientific article

Vascular endothelial growth factor increases the ultrafiltration coefficient in isolated intact Wistar rat glomeruli

scientific article published on 20 October 2005

Vascular endothelial growth factor-A165b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina

scientific article

Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration.

scientific article published on October 2015

Vascular endothelial growth factor-C (VEGF-C) expression in normal human tissues.

scientific article published on January 2006

ZM323881, a novel inhibitor of vascular endothelial growth factor-receptor-2 tyrosine kinase activity.

scientific article published in December 2002

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