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List of works by Jon D Lane

A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress ⬇️

scientific article published on April 1, 2012

A heterodimeric SNX4:SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly

scientific article published on 08 June 2020

A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons

scientific article published on 14 April 2020

A novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentation

scientific article

Active relocation of chromatin and endoplasmic reticulum into blebs in late apoptotic cells.

scientific article published on September 2005

Alternative macroautophagy

scientific article published on 07 February 2010

Apoptotic cleavage of cytoplasmic dynein intermediate chain and p150(Glued) stops dynein-dependent membrane motility.

scientific article published on June 2001

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

scientific article

Autophagy and Redox Homeostasis in Parkinson's: A Crucial Balancing Act

scientific article published on 10 November 2020

Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation.

scientific article published on 18 March 2013

CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer's disease

scientific article

Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis.

scientific article

Caspase cleavage of the Golgi stacking factor GRASP65 is required for Fas/CD95-mediated apoptosis

scientific article

DNA damage signalling from the placenta to foetal blood as a potential mechanism for childhood leukaemia initiation

scientific article published on 13 March 2019

Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase

scientific article

Editorial: Self-Eating on Demand: Autophagy in Cancer and Cancer Therapy

scientific article published on 7 December 2017

Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation

scientific article published on 02 December 2021

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Imaging Autophagy in hiPSC-Derived Midbrain Dopaminergic Neuronal Cultures for Parkinson's Disease Research

scientific article published on 01 January 2019

Induced Pluripotent Stem Cell Neuronal Models for the Study of Autophagy Pathways in Human Neurodegenerative Disease.

scientific article

Influence of particle size and reactive oxygen species on cobalt chrome nanoparticle-mediated genotoxicity

scientific article published on 20 February 2013

Mathematical Modeling Highlights the Complex Role of AKT in TRAIL-Induced Apoptosis of Colorectal Carcinoma Cells

scientific article published on 14 January 2019

Maturing reticulocytes internalize plasma membrane in glycophorin A-containing vesicles that fuse with autophagosomes before exocytosis.

scientific article

Mitochondrial import, health and mtDNA copy number variability using type II and type V CRISPR effectors

scientific article published on 25 August 2020

Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes

scientific article published on 02 April 2018

Nanoparticles can cause DNA damage across a cellular barrier

scientific article

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.

scientific article published on 22 January 2015

SIRT3: A Central Regulator of Mitochondrial Adaptation in Health and Disease

scientific article published on March 2013

Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions.

scientific article published on 10 May 2014

Signalling mechanisms in autophagy: an introduction to the issue

scientific article

Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells.

scientific article published on 11 June 2015

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2.

scientific article published on 11 August 2005

The ins and outs of human reticulocyte maturation: autophagy and the endosome/exosome pathway

scientific article published on 4 June 2012

Transautophagy: Research and Translation of Autophagy Knowledge.

scientific article

USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death

scientific article

Zebrafish as a model to study autophagy and its role in skeletal development and disease

scientific article published on 11 September 2020

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