List of works - Timothy J Bussey

A computer-automated touchscreen paired-associates learning (PAL) task for mice: impairments following administration of scopolamine or dicyclomine and improvements following donepezil

scientific article published on 18 November 2010

A glycine antagonist 7-chlorokynurenic acid attenuates ischemia-induced learning deficits

scientific article published in February 1993

A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo

scientific article published in September 1992

A new touchscreen test of pattern separation: effect of hippocampal lesions.

scientific article published in June 2009

A novel 2- and 3-choice touchscreen-based continuous trial-unique nonmatching-to-location task (cTUNL) sensitive to functional differences between dentate gyrus and CA3 subregions of the hippocampus

scientific article published on 30 July 2015

A novel touchscreen-automated paired-associate learning (PAL) task sensitive to pharmacological manipulation of the hippocampus: a translational rodent model of cognitive impairments in neurodegenerative disease

scientific article

Abnormal categorization and perceptual learning in patients with hippocampal damage.

scientific article published in July 2006

Accumbal Cholinergic Interneurons Differentially Influence Motivation Related to Satiety Signaling

scientific article

Adult hippocampal neurogenesis and its role in cognition

scientific article

Animal models of amnesia

scientific article published on 01 July 2010

Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia

scientific article

BDNF in the dentate gyrus is required for consolidation of "pattern-separated" memories

scientific article published on 24 October 2013

Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories

scientific article published on 23 May 2014

Bridging the translational divide: identical cognitive touchscreen testing in mice and humans carrying mutations in a disease-relevant homologous gene

scientific article

Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.

scientific article

Can animals recall the past and plan for the future?

scientific article

Chronic alcohol produces neuroadaptations to prime dorsal striatal learning

scientific article published on 19 August 2013

Comparing the effects of subchronic phencyclidine and medial prefrontal cortex dysfunction on cognitive tests relevant to schizophrenia

scientific article published on 21 July 2015

Components of recognition memory: Dissociable cognitive processes or just differences in representational complexity? ⬇️

scientific article published on November 1, 2010

Conditional motor learning in the nonspatial domain: effects of errorless learning and the contribution of the fornix to one-trial learning.

scientific article published in June 2005

Consideration of species differences in developing novel molecules as cognition enhancers

scientific article published on 12 October 2012

Different roles for M1 and M2 receptors within perirhinal cortex in object recognition and discrimination

scientific article published on 24 January 2014

Discrimination of computer-graphic stimuli by mice: a method for the behavioral characterization of transgenic and gene-knockout models.

scientific article published in August 2001

Discrimination of multidimensional visual stimuli by mice: intra- and extradimensional shifts.

scientific article published in June 2005

Dissociable effects of AMPA-induced lesions of the vertical limb diagonal band of Broca on performance of the 5-choice serial reaction time task and on acquisition of a conditional visual discrimination.

scientific article published in December 1996

Dissociable effects of anterior and posterior cingulate cortex lesions on the acquisition of a conditional visual discrimination: facilitation of early learning vs. impairment of late learning.

scientific article published on December 1996

Dissociable effects of cingulate and medial frontal cortex lesions on stimulus-reward learning using a novel Pavlovian autoshaping procedure for the rat: implications for the neurobiology of emotion

scientific article

Dissociation between memory retention across a delay and pattern separation following medial prefrontal cortex lesions in the touchscreen TUNL task

scientific article published on 6 February 2013

Distinct patterns of behavioural impairments resulting from fornix transection or neurotoxic lesions of the perirhinal and postrhinal cortices in the rat.

scientific article published in June 2000

Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?

scientific article published on 15 June 2011

Do your glial cells make you clever?

scientific article published in March 2013

Double dissociation between the effects of peri-postrhinal cortex and hippocampal lesions on tests of object recognition and spatial memory: heterogeneity of function within the temporal lobe.

scientific article

Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable?

scientific article published on 07 July 2011

Effects of selective thalamic and prelimbic cortex lesions on two types of visual discrimination and reversal learning

scientific article published in September 2001

Erratum to: The role of the dorsal hippocampus in two versions of the touchscreen automated paired associates learning (PAL) task for mice

scientific article published on 25 July 2015

Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior

scientific article

Extensive cytotoxic lesions involving both the rhinal cortices and area TE impair recognition but spare spatial alternation in the rat.

scientific article published in January 1997

FK962 and donepezil act synergistically to improve cognition in rats: potential as an add-on therapy for Alzheimer's disease

scientific article published on 2 December 2010

Facilitation of spatial working memory performance following intra-prefrontal cortical administration of the adrenergic alpha1 agonist phenylephrine.

scientific article published on 12 August 2015

False recognition in a mouse model of Alzheimer's disease: rescue with sensory restriction and memantine.

scientific article

Fornix lesions can facilitate acquisition of the transverse patterning task: a challenge for "configural" theories of hippocampal function.

scientific article

Fornix transection impairs conditional visuomotor learning in tasks involving nonspatially differentiated responses.

scientific article published in January 2002

Functional dissociations within the ventral object processing pathway: cognitive modules or a hierarchical continuum?

scientific article

Functional specialization in the human medial temporal lobe.

scientific article published in November 2005

Functionally dissociating aspects of event memory: the effects of combined perirhinal and postrhinal cortex lesions on object and place memory in the rat.

scientific article published in January 1999

Genetic and dopaminergic modulation of reversal learning in a touchscreen-based operant procedure for mice

scientific article published on 19 May 2006

GluN2B in corticostriatal circuits governs choice learning and choice shifting.

scientific article

Glutamate receptors in perirhinal cortex mediate encoding, retrieval, and consolidation of object recognition memory.

scientific article published in April 2005

Heightened susceptibility to interference in an animal model of amnesia: impairment in encoding, storage, retrieval--or all three?

scientific article

Hippocampal lesions in rats impair learning and memory for locations on a touch-sensitive computer screen: the "ASAT" task

scientific article published on 20 April 2008

Hippocampal lesions that abolish spatial maze performance spare object recognition memory at delays of up to 48 hours.

scientific article published in January 2005

Impaired attention in the 3xTgAD mouse model of Alzheimer's disease: rescue by donepezil (Aricept).

scientific article

Impaired discrimination learning in interneuronal NMDAR-GluN2B mutant mice

scientific article published on June 2015

Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit.

scientific article published on 28 January 2008

Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain

scientific article published on August 2008

Impairment and facilitation of transverse patterning after lesions of the perirhinal cortex and hippocampus, respectively.

scientific article published in February 2006

Impairments in visual discrimination after perirhinal cortex lesions: testing 'declarative' vs. 'perceptual-mnemonic' views of perirhinal cortex function

scientific article published in February 2003

Implications of animal object memory research for human amnesia.

scientific article published on 02 February 2010

Influence of conceptual knowledge on visual object discrimination: insights from semantic dementia and MTL amnesia

scientific article published on 11 February 2010

Intact attentional processing but abnormal responding in M1 muscarinic receptor-deficient mice using an automated touchscreen method.

scientific article published on 30 August 2011

Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions.

scientific article published in October 2000

Interaction of ventral and orbital prefrontal cortex with inferotemporal cortex in conditional visuomotor learning

scientific article published in August 2002

Measuring Motivation and Reward-Related Decision Making in the Rodent Operant Touchscreen System

scientific article published on 4 January 2016

Measuring cognitive deficits in disabled mice using an automated interactive touchscreen system

Molecular Mechanisms in Perirhinal Cortex Selectively Necessary for Discrimination of Overlapping Memories, but Independent of Memory Persistence.

scientific article published in September 2017

Motivational assessment of mice using the touchscreen operant testing system: effects of dopaminergic drugs.

scientific article published on 10 July 2015

Multiple cognitive abilities from a single cortical algorithm

scientific article published on 25 May 2012

Muscimol, AP5, or scopolamine infused into perirhinal cortex impairs two-choice visual discrimination learning in rats

scientific article published on 13 October 2009

New translational assays for preclinical modelling of cognition in schizophrenia: the touchscreen testing method for mice and rats

scientific article

No effect of hippocampal lesions on perirhinal cortex-dependent feature-ambiguous visual discriminations.

scientific article published in January 2006

Object recognition memory: neurobiological mechanisms of encoding, consolidation and retrieval.

scientific article published on 24 April 2008

Paradoxical facilitation of object recognition memory after infusion of scopolamine into perirhinal cortex: implications for cholinergic system function.

scientific article published in September 2006

Perceptual deficits in amnesia: challenging the medial temporal lobe 'mnemonic' view.

scientific article published in January 2005

Perceptual functions of perirhinal cortex in rats: zero-delay object recognition and simultaneous oddity discriminations.

scientific article published in March 2007

Performance of transgenic TgTau-P301L mice in a 5-choice serial reaction time task (5-CSRTT) as a model of Alzheimer's disease

scientific article published on September 2015

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology

scientific article

Perirhinal cortex and feature-ambiguous discriminations

scientific article published in March 2006

Perirhinal cortex and place–object conditional learning in the rat

scientific article published on 01 August 2001

Perirhinal cortex resolves feature ambiguity in complex visual discriminations

scientific article published in January 2002

Perirhinal cortex resolves feature ambiguity in configural object recognition and perceptual oddity tasks.

scientific article

Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice

scientific article

Prometheus to Proust: the case for behavioural criteria for 'mental time travel'.

scientific article published in October 2003

Rats spontaneously discriminate purely visual, two-dimensional stimuli in tests of recognition memory and perceptual oddity

scientific article published in October 2007

Removal of cholinergic input to perirhinal cortex disrupts object recognition but not spatial working memory in the rat.

scientific article published on April 2005

Reply

Reward-related behavioral paradigms for addiction research in the mouse: performance of common inbred strains

scientific article

Role of the anterior cingulate cortex in the control over behavior by Pavlovian conditioned stimuli in rats

scientific article

Role of the hippocampal system in associative learning beyond the spatial domain

scientific article published in May 2003

Running enhances spatial pattern separation in mice

scientific article

Scopolamine infused into perirhinal cortex improves object recognition memory by blocking the acquisition of interfering object information

scientific article

Specialization in the medial temporal lobe for processing of objects and scenes

scientific article published in January 2005

Spontaneous object recognition and its relevance to schizophrenia: a review of findings from pharmacological, genetic, lesion and developmental rodent models.

scientific article

Strains and stressors: an analysis of touchscreen learning in genetically diverse mouse strains

scientific article

Synaptic scaffold evolution generated components of vertebrate cognitive complexity.

scientific article

TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function

scientific article published on October 2012

The NEWMEDS rodent touchscreen test battery for cognition relevant to schizophrenia.

scientific article published on 24 July 2015

The continuous performance test (rCPT) for mice: a novel operant touchscreen test of attentional function

scientific article published on 29 September 2015

The orexigenic hormone acyl-ghrelin increases adult hippocampal neurogenesis and enhances pattern separation

scientific article

The organization of visual object representations: a connectionist model of effects of lesions in perirhinal cortex

scientific article published in January 2002

The parahippocampal region and object identification.

scientific article published in June 2000

The perceptual-mnemonic/feature conjunction model of perirhinal cortex function.

scientific article

The representational-hierarchical view of pattern separation: Not just hippocampus, not just space, not just memory?

scientific article published on 30 January 2016

The role of the dorsal hippocampus in two versions of the touchscreen automated paired associates learning (PAL) task for mice

scientific article

The role of ventral and orbital prefrontal cortex in conditional visuomotor learning and strategy use in rhesus monkeys (Macaca mulatta).

scientific article

The touchscreen cognitive testing method for rodents: how to get the best out of your rat.

scientific article published on 8 July 2008

The touchscreen operant platform for assessing executive function in rats and mice

scientific article

The touchscreen operant platform for testing learning and memory in rats and mice

scientific article

The touchscreen operant platform for testing working memory and pattern separation in rats and mice.

scientific article published on 19 September 2013

Transient inactivation of perirhinal cortex disrupts encoding, retrieval, and consolidation of object recognition memory.

scientific article published in January 2005

Trial-unique, delayed nonmatching-to-location (TUNL) touchscreen testing for mice: sensitivity to dorsal hippocampal dysfunction

scientific article

Trial-unique, delayed nonmatching-to-location (TUNL): a novel, highly hippocampus-dependent automated touchscreen test of location memory and pattern separation.

scientific article published on 6 August 2010

Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat.

scientific article

Why does brain damage impair memory? A connectionist model of object recognition memory in perirhinal cortex.

scientific article published in November 2006

List of works by Timothy J Bussey

A computer-automated touchscreen paired-associates learning (PAL) task for mice: impairments following administration of scopolamine or dicyclomine and improvements following donepezil

A glycine antagonist 7-chlorokynurenic acid attenuates ischemia-induced learning deficits

A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo

A new touchscreen test of pattern separation: effect of hippocampal lesions.

A novel 2- and 3-choice touchscreen-based continuous trial-unique nonmatching-to-location task (cTUNL) sensitive to functional differences between dentate gyrus and CA3 subregions of the hippocampus

A novel touchscreen-automated paired-associate learning (PAL) task sensitive to pharmacological manipulation of the hippocampus: a translational rodent model of cognitive impairments in neurodegenerative disease

Abnormal categorization and perceptual learning in patients with hippocampal damage.

Accumbal Cholinergic Interneurons Differentially Influence Motivation Related to Satiety Signaling

Adult hippocampal neurogenesis and its role in cognition

Animal models of amnesia

Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia

BDNF in the dentate gyrus is required for consolidation of "pattern-separated" memories

Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories

Bridging the translational divide: identical cognitive touchscreen testing in mice and humans carrying mutations in a disease-relevant homologous gene

Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.

Can animals recall the past and plan for the future?

Chronic alcohol produces neuroadaptations to prime dorsal striatal learning

Comparing the effects of subchronic phencyclidine and medial prefrontal cortex dysfunction on cognitive tests relevant to schizophrenia

Components of recognition memory: Dissociable cognitive processes or just differences in representational complexity? ⬇️

Conditional motor learning in the nonspatial domain: effects of errorless learning and the contribution of the fornix to one-trial learning.

Consideration of species differences in developing novel molecules as cognition enhancers

Different roles for M1 and M2 receptors within perirhinal cortex in object recognition and discrimination

Discrimination of computer-graphic stimuli by mice: a method for the behavioral characterization of transgenic and gene-knockout models.

Discrimination of multidimensional visual stimuli by mice: intra- and extradimensional shifts.

Dissociable effects of AMPA-induced lesions of the vertical limb diagonal band of Broca on performance of the 5-choice serial reaction time task and on acquisition of a conditional visual discrimination.

Dissociable effects of anterior and posterior cingulate cortex lesions on the acquisition of a conditional visual discrimination: facilitation of early learning vs. impairment of late learning.

Dissociable effects of cingulate and medial frontal cortex lesions on stimulus-reward learning using a novel Pavlovian autoshaping procedure for the rat: implications for the neurobiology of emotion

Dissociation between memory retention across a delay and pattern separation following medial prefrontal cortex lesions in the touchscreen TUNL task

Distinct patterns of behavioural impairments resulting from fornix transection or neurotoxic lesions of the perirhinal and postrhinal cortices in the rat.

Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?

Do your glial cells make you clever?

Double dissociation between the effects of peri-postrhinal cortex and hippocampal lesions on tests of object recognition and spatial memory: heterogeneity of function within the temporal lobe.

Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable?

Effects of selective thalamic and prelimbic cortex lesions on two types of visual discrimination and reversal learning

Erratum to: The role of the dorsal hippocampus in two versions of the touchscreen automated paired associates learning (PAL) task for mice

Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior

Extensive cytotoxic lesions involving both the rhinal cortices and area TE impair recognition but spare spatial alternation in the rat.

FK962 and donepezil act synergistically to improve cognition in rats: potential as an add-on therapy for Alzheimer's disease

Facilitation of spatial working memory performance following intra-prefrontal cortical administration of the adrenergic alpha1 agonist phenylephrine.

False recognition in a mouse model of Alzheimer's disease: rescue with sensory restriction and memantine.

Fornix lesions can facilitate acquisition of the transverse patterning task: a challenge for "configural" theories of hippocampal function.

Fornix transection impairs conditional visuomotor learning in tasks involving nonspatially differentiated responses.

Functional dissociations within the ventral object processing pathway: cognitive modules or a hierarchical continuum?

Functional specialization in the human medial temporal lobe.

Functionally dissociating aspects of event memory: the effects of combined perirhinal and postrhinal cortex lesions on object and place memory in the rat.

Genetic and dopaminergic modulation of reversal learning in a touchscreen-based operant procedure for mice

GluN2B in corticostriatal circuits governs choice learning and choice shifting.

Glutamate receptors in perirhinal cortex mediate encoding, retrieval, and consolidation of object recognition memory.

Heightened susceptibility to interference in an animal model of amnesia: impairment in encoding, storage, retrieval--or all three?

Hippocampal lesions in rats impair learning and memory for locations on a touch-sensitive computer screen: the "ASAT" task

Hippocampal lesions that abolish spatial maze performance spare object recognition memory at delays of up to 48 hours.

Impaired attention in the 3xTgAD mouse model of Alzheimer's disease: rescue by donepezil (Aricept).

Impaired discrimination learning in interneuronal NMDAR-GluN2B mutant mice

Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit.

Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain

Impairment and facilitation of transverse patterning after lesions of the perirhinal cortex and hippocampus, respectively.

Impairments in visual discrimination after perirhinal cortex lesions: testing 'declarative' vs. 'perceptual-mnemonic' views of perirhinal cortex function

Implications of animal object memory research for human amnesia.

Influence of conceptual knowledge on visual object discrimination: insights from semantic dementia and MTL amnesia

Intact attentional processing but abnormal responding in M1 muscarinic receptor-deficient mice using an automated touchscreen method.

Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions.

Interaction of ventral and orbital prefrontal cortex with inferotemporal cortex in conditional visuomotor learning

Measuring Motivation and Reward-Related Decision Making in the Rodent Operant Touchscreen System

Measuring cognitive deficits in disabled mice using an automated interactive touchscreen system

Molecular Mechanisms in Perirhinal Cortex Selectively Necessary for Discrimination of Overlapping Memories, but Independent of Memory Persistence.

Motivational assessment of mice using the touchscreen operant testing system: effects of dopaminergic drugs.

Multiple cognitive abilities from a single cortical algorithm

Muscimol, AP5, or scopolamine infused into perirhinal cortex impairs two-choice visual discrimination learning in rats

New translational assays for preclinical modelling of cognition in schizophrenia: the touchscreen testing method for mice and rats

No effect of hippocampal lesions on perirhinal cortex-dependent feature-ambiguous visual discriminations.

Object recognition memory: neurobiological mechanisms of encoding, consolidation and retrieval.

Paradoxical facilitation of object recognition memory after infusion of scopolamine into perirhinal cortex: implications for cholinergic system function.

Perceptual deficits in amnesia: challenging the medial temporal lobe 'mnemonic' view.

Perceptual functions of perirhinal cortex in rats: zero-delay object recognition and simultaneous oddity discriminations.

Performance of transgenic TgTau-P301L mice in a 5-choice serial reaction time task (5-CSRTT) as a model of Alzheimer's disease

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology

Perirhinal cortex and feature-ambiguous discriminations

Perirhinal cortex and place–object conditional learning in the rat

Perirhinal cortex resolves feature ambiguity in complex visual discriminations