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List of works by Claude-Henry Volmar

A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease

An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C)

BET bromodomain proteins are required for glioblastoma cell proliferation.

scientific article

Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice

scientific article published in July 2004

CD40 deficiency mitigates Alzheimer's disease pathology in transgenic mouse models

scientific article published on 24 February 2006

CD40 ligation mediates plaque-associated tau phosphorylation in beta-amyloid overproducing mice.

scientific article

CD40/CD40L interaction induces Abeta production and increases gamma-secretase activity independently of tumor necrosis factor receptor associated factor (TRAF) signaling

scientific article

Characterization of an agonist probe for opioid receptor mu 1 (OPRM1)-opioid receptor delta 1 (OPRD1) heterodimerization

Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's disease

scientific article published on 2 October 2008

Differential effects of the Gβ5-RGS7 complex on muscarinic M3 receptor-induced Ca2+ influx and release.

scientific article

Drug and disease signature integration identifies synergistic combinations in glioblastoma

scientific article published in Nature Communications

Dual screen for efficacy and toxicity identifies HDAC inhibitor with distinctive activity spectrum for BAP1-mutant uveal melanoma

scientific article published on 19 October 2020

Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins

scientific article published on 30 November 2018

Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma

scientific article published in PLoS ONE

Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study.

scientific article published on 11 November 2017

Genomic regulation after CD40 stimulation in microglia: Relevance to Alzheimer's disease

scientific article published on 22 September 2005

HDAC Inhibitors Induce Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons

scientific article published on 05 March 2019

Helix 8 and the i3 loop of the muscarinic M3 receptor are crucial sites for its regulation by the Gβ5-RGS7 complex

scientific article

Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model

article published in the Proceedings of the National Academy of Sciences of the United States of America

Longevity-related molecular pathways are subject to midlife "switch" in humans

scientific article published on 06 June 2019

M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory

scientific article published on 9 October 2017

Model of Alzheimer's disease amyloid-beta peptide based on a RNA binding protein

scientific article published on July 2005

Neuropeptide Y Y2 antagonist treated ovariectomized mice exhibit greater bone mineral density.

scientific article published on 7 November 2017

Optimization and characterization of an antagonist for vasopressin 1a (V1a) receptor

Orphan diseases: state of the drug discovery art.

scientific article

Plasticity of the electric organ discharge waveform of male Brachyhypopomus pinnicaudatus . II. Social effects

scientific article published on 01 February 2001

Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue

scientific article published on 30 November 2018

Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier

scientific article published on 17 December 2010

The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers.

scientific article

The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease

scientific article published on 26 April 2016

The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation

scientific article published on 25 June 2015

The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid beta (Abeta) production.

scientific article published on 22 April 2008

Transcriptional repression of ER through hMAPK dependent histone deacetylation by class I HDACs.

scientific article published on 17 August 2014

Vitamin C sensitizes melanoma to BET inhibitors.

scientific article published on 27 November 2017