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List of works by Marcela Pekna

Absence of glial fibrillary acidic protein and vimentin prevents hypertrophy of astrocytic processes and improves post-traumatic regeneration.

scientific article

Altered cognitive performance and synaptic function in the hippocampus of mice lacking C3.

scientific article published on 28 December 2013

Astrocyte intermediate filaments in CNS pathologies and regeneration.

scientific article published in November 2004

Astrocytes negatively regulate neurogenesis through the Jagged1-mediated Notch pathway.

scientific article

Attenuation of reactive gliosis does not affect infarct volume in neonatal hypoxic-ischemic brain injury in mice

scientific article published on 28 April 2010

Axonal regeneration after sciatic nerve lesion is delayed but complete in GFAP- and vimentin-deficient mice

scientific article

Bioactive 3D cell culture system minimizes cellular stress and maintains the in vivo-like morphological complexity of astroglial cells.

scientific article published on 7 January 2013

Biocompatibility of heparin-coated circuits used in cardiopulmonary bypass

scientific article published on 01 January 1994

Cardioembolic and small vessel disease stroke show differences in associations between systemic C3 levels and outcome

scientific article

Circulating cytokines and granulocyte-derived enzymes during complex heart surgery. A clinical study with special reference to heparin-coating of cardiopulmonary bypass circuits

scientific article published on 01 January 1995

Complement C3 contributes to ethanol-induced liver steatosis in mice

scientific article published in January 2006

Complement Deficiency Ameliorates Collagen-Induced Arthritis in Mice

scientific article published on 01 July 2002

Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis

scientific article published in April 2004

Complement activation by polymethyl methacrylate minimized by end-point heparin attachment

scientific article published on 01 February 1993

Complement activation during cardiopulmonary bypass: Effects of immobilized heparin

scientific article published on 01 August 1994

Complement gene single nucleotide polymorphisms and biomarker endophenotypes of Alzheimer's disease

scientific article published in January 2013

Complement opsonization enhances friend virus infection of B cells and thereby amplifies the virus-specific CD8+ T cell response

scientific article published on 3 November 2010

Complement system response to decompression

scientific article published on 01 March 1996

Complement-derived anaphylatoxin C3a regulates in vitro differentiation and migration of neural progenitor cells.

scientific article published in November 2009

Defining cell populations with single-cell gene expression profiling: correlations and identification of astrocyte subpopulations

scientific article published on 25 November 2010

Effect of chronic ethanol consumption on the expression of complement components and acute-phase proteins in liver

scientific article published on 22 June 2007

Evidence for iC3 generation during cardiopulmonary bypass as the result of blood-gas interaction

scientific article published on 01 March 1993

Generation of iC3 at the interface between blood and gas.

scientific article

Genetic variation in complement component C3 shows association with ischaemic stroke

scientific article published on 17 March 2011

Glial cells in (patho)physiology

scientific article

Grafting of neural stem and progenitor cells to the hippocampus of young, irradiated mice causes gliosis and disrupts the granule cell layer.

scientific article published on 18 April 2013

Immunoglobulin treatment reduces atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice via the complement system

scientific article published on 01 December 2005

Increased cell proliferation and neurogenesis in the hippocampal dentate gyrus of old GFAP(-/-)Vim(-/-) mice

scientific article published in November 2004

Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis

article published in the Proceedings of the National Academy of Sciences of the United States of America

Intermediate filaments are important for astrocyte response to oxidative stress induced by oxygen-glucose deprivation and reperfusion

scientific article published on 12 June 2013

Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice

scientific article published in April 2004

Mice Deficient for the Complement Factor B Develop and Reproduce Normally

scientific article published on 01 April 1998

Modulation of neural plasticity as a basis for stroke rehabilitation.

scientific article published on 23 August 2012

Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis.

scientific article

PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and Alveogenesis

article

Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli

scientific journal article

Photothrombosis-Induced Infarction of the Mouse Cerebral Cortex Is Not Affected by the Nrf2-Activator Sulforaphane ⬇️

scientific article published on July 23, 2012

Plasma C3 and C3a Levels in Cryptogenic and Large-Vessel Disease Stroke: Associations with Outcome

scientific article published on 28 June 2011

Plasticity response in the contralesional hemisphere after subtle neurotrauma: gene expression profiling after partial deafferentation of the hippocampus

scientific article

Protective Role of Reactive Astrocytes in Brain Ischemia

scientific article published on 29 August 2007

Receptor for complement peptide C3a: a therapeutic target for neonatal hypoxic-ischemic brain injury

scientific article published on 4 June 2013

Reduced removal of synaptic terminals from axotomized spinal motoneurons in the absence of complement C3.

scientific article published on 19 June 2012

Response to Quinlan and Nilsson: Astroglia sitting at the controls?

scientific article published on 01 May 2004

Short general anaesthesia induces prolonged changes in gene expression in the mouse hippocampus.

scientific article

Signaling through C5aR is not involved in basal neurogenesis.

scientific article

Targeted disruption of the murine gene coding for the third complement component (C3).

scientific article published in January 1998

The complement-derived anaphylatoxin C5a increases microglial GLT-1 expression and glutamate uptake in a TNF-alpha-independent manner

scientific article published in January 2009

The dual role of astrocyte activation and reactive gliosis.

scientific article published on 07 January 2014

The impact of genetic removal of GFAP and/or vimentin on glutamine levels and transport of glucose and ascorbate in astrocytes

scientific article published on 01 November 1999

The neurobiology of brain injury

scientific article published on 30 July 2012

The role of astrocytes and complement system in neural plasticity.

scientific article published on January 2007

Trace fear conditioning detects hypoxic-ischemic brain injury in neonatal mice

scientific article published on 21 July 2011

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