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List of works by Matthew A. Cooper

A Comparative Study of Impedance versus Optical Label-Free Systems Relative to Labelled Assays in a Predominantly Gi Coupled GPCR (C5aR) Signalling.

scientific article

A Survey of the 2010 Quartz Crystal Microbalance Literature ⬇️

scientific article published on September 1, 2012

A biophysical characterisation of factors controlling dimerisation and selectivity in the NF-kappaB and NFAT families

scientific article published in June 2004

A community-based approach to new antibiotic discovery

scientific article

A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance

scientific article

A high sensitivity assay for the inflammatory marker C-Reactive protein employing acoustic biosensing.

scientific article

A new antibiotic with potent activity targets MscL.

scientific article published on 4 February 2015

A novel method of resistance for influenza against a channel-blocking antiviral drug

scientific article published in May 2004

A paramagnetic-reporter two-particle system for amplification-free detection of DNA in serum

scientific article published on 16 July 2013

A signal amplification assay for HSV type 1 viral DNA detection using nanoparticles and direct acoustic profiling

article published in 2010

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

scientific article

A survey of the 2001 to 2005 quartz crystal microbalance biosensor literature: applications of acoustic physics to the analysis of biomolecular interactions.

scientific article published on May 2007

A survey of the 2006–2009 quartz crystal microbalance biosensor literature ⬇️

scientific article published on September 1, 2011

A vesicle capture sensor chip for kinetic analysis of interactions with membrane-bound receptors

scientific article published in January 2000

Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.

scientific article published on 6 January 2016

Advances in membrane receptor screening and analysis.

scientific article

Aminoglycoside antibiotics in the 21st century.

scientific article

Amplification free detection of herpes simplex virus DNA.

scientific article published on 2 March 2011

An "Unlikely" Pair: The Antimicrobial Synergy of Polymyxin B in Combination with the Cystic Fibrosis Transmembrane Conductance Regulator Drugs KALYDECO and ORKAMBI.

scientific article published on 17 May 2016

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

scientific article published on 23 June 2020

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

scientific article published on 14 June 2014

An optimised Cu(0)-RDRP approach for the synthesis of lipidated oligomeric vinyl azlactone: toward a versatile antimicrobial materials screening platform

scientific article published on 11 October 2019

An optimized whole blood assay measuring expression and activity of NLRP3-, NLRC4 and AIM2-inflammasomes.

scientific article published on 28 September 2015

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin

scientific article published on April 2014

Antibacterial Low Molecular Weight Cationic Polymers: Dissecting the Contribution of Hydrophobicity, Chain Length and Charge to Activity

scientific article

Antibacterial Nerol Cinnamates from the Australian Plant Eremophila longifolia

scientific article

Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F.

scientific article published on 29 December 2015

Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca.

scientific article published on 18 April 2013

Antibiotics in the clinical pipeline at the end of 2015.

scientific article

Antibiotics in the clinical pipeline in 2011 ⬇️

scientific article published on May 18, 2011

Antibiotics in the clinical pipeline in 2013.

scientific article published on 04 September 2013

Antitubercular and Antiparasitic 2-Nitroimidazopyrazinones with Improved Potency and Solubility

scientific article published on 05 November 2020

Binding of glycopeptide antibiotics to a model of a vancomycin-resistant bacterium.

scientific article

Binding of vancomycin group antibiotics to d -alanine and d -lactate presenting self-assembled monolayers

scientific article published on 01 November 2000

Biofunctionalized protein resistant oligo(ethylene glycol)-derived polymer brushes as selective immobilization and sensing platforms

scientific article published in October 2009

Biomarkers in chronic kidney disease: a review

scientific article published on 22 June 2011

Biosensor profiling of molecular interactions in pharmacology.

scientific article published on October 2003

C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2.

scientific article published on 24 September 2013

C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment.

scientific article published on 29 April 2014

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

scientific article published on 21 July 2015

Cationic Acrylate Oligomers Comprising Amino Acid Mimic Moieties Demonstrate Improved Antibacterial Killing Efficiency.

scientific article published on 13 December 2016

Cell- and biomarker-based assays for predicting nephrotoxicity

scientific article

Characterisation of small molecule ligands 4CMTB and 2CTAP as modulators of human FFA2 receptor signalling

scientific article published in Scientific Reports

Chemical philanthropy: a path forward for antibiotic discovery?

scientific article

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice

scientific article

Clostridium difficile drug pipeline: challenges in discovery and development of new agents

scientific article published on 30 March 2015

Comparison of surface plasmon resonance, resonant waveguide grating biosensing and enzyme linked immunosorbent assay (ELISA) in the evaluation of a dengue virus immunoassay.

scientific article

Complete Genome Sequence of Klebsiella quasipneumoniae subsp. similipneumoniae Strain ATCC 700603

scientific article (publication date: 26 May 2016)

Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

scientific article published on 29 April 2016

Derivation of ligands for the complement C3a receptor from the C-terminus of C5a

scientific article

Design, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activity

scientific article published on 11 December 2018

Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM).

scientific article

Development of anti-infectives using phage display: biological agents against bacteria, viruses, and parasites.

scientific article

Developments in Glycopeptide Antibiotics

scientific article

Direct acoustic profiling of DNA hybridisation using HSV type 1 viral sequences

scientific article published on 21 September 2007

Direct and sensitive detection of a human virus by rupture event scanning.

scientific article

Direct quantification of analyte concentration by resonant acoustic profiling.

scientific article

Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling.

scientific article

Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach

scientific article published on 30 March 2015

Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans

scientific article published on 17 August 2016

Drug-binding energetics of human α-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations.

scientific article

Drug-drug plasma protein binding interactions of ivacaftor

scientific article published on 24 February 2015

Drug-likeness and increased hydrophobicity of commercially available compound libraries for drug screening.

scientific article

Efficient synthesis of anacardic acid analogues and their antibacterial activities.

scientific article published on 29 January 2013

Emerging pathogenic links between microbiota and the gut-lung axis.

scientific article

Enhancement of antibiotic-activity through complexation with metal ions - Combined ITC, NMR, enzymatic and biological studies.

scientific article published on 24 November 2016

Ethanol Concentration Influences the Mechanisms of Wine Tannin Interactions with Poly(L-proline) in Model Wine

scientific article published on 22 April 2015

Evaluation of direct versus multi-layer passivation and capture chemistries for nanoparticle-based biosensor applications

scientific article published on 28 September 2014

Exploiting macromolecular design to optimize the antibacterial activity of alkylated cationic oligomers

scientific article published on 06 November 2018

Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids

scientific article published on 01 March 2015

Fine Tuning the Disassembly Time of Thermoresponsive Polymer Nanoparticles

scientific article published on 26 September 2013

Fix the antibiotics pipeline.

scientific article

Flemingin-Type Prenylated Chalcones from the Sarawak Rainforest Plant Desmodium congestum

scientific article published on 18 August 2015

Fluorescent Trimethoprim Conjugate Probes To Assess Drug Accumulation in Wild Type and Mutant Escherichia coli

scientific article published on 16 August 2016

Fluorogenic pyrosequencing in microreactors ⬇️

scientific article published on June 29, 2011

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

scientific article published on 17 May 2019

From Breast Cancer to Antimicrobial: Combating Extremely Resistant Gram-Negative "Superbugs" Using Novel Combinations of Polymyxin B with Selective Estrogen Receptor Modulators.

scientific article

G-Quadruplex-Specific Peptide−Hemicyanine Ligands by Partial Combinatorial Selection

scientific article published on 01 May 2003

Genomic characterization of the uncultured Bacteroidales family S24-7 inhabiting the guts of homeothermic animals

scientific article

Glycopeptide antibiotics: back to the future.

scientific article published on 13 August 2014

Helping Chemists Discover New Antibiotics.

scientific article published on 13 May 2015

Human Monocytes Engage an Alternative Inflammasome Pathway

scientific article published on 28 March 2016

Identification of antitubercular benzothiazinone compounds by ligand-based design

scientific article published on 31 August 2012

Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.

scientific article published on 27 September 2016

Imperfect coordination chemistry facilitates metal ion release in the Psa permease

scientific article

Improved Immunoassay Sensitivity in Serum as a Result of Polymer-Entrapped Quantum Dots: 'Papaya Particles'.

scientific article published on 22 May 2015

In vitro Antimicrobial Activity of Acne Drugs Against Skin-Associated Bacteria

scientific article published on 10 October 2019

In vivo evolution of antimicrobial resistance in a series of Staphylococcus aureus patient isolates: the entire picture or a cautionary tale?

scientific article published on 18 September 2013

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice.

scientific article published on 23 June 2015

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

scientific article published on 01 October 2018

Inflammasomes in COPD and neutrophilic asthma

scientific article published on 22 October 2015

Inflammasomes in the lung.

scientific article published on 24 January 2017

Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice.

scientific article published on 18 December 2016

Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction

scientific article published on 30 August 2014

Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes

scientific article

K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

scientific article

Kinetic analysis of antibody-antigen interactions at a supported lipid monolayer

scientific article published in December 1999

Kinetically selective binding of single stranded RNA over DNA by a pyrrolidine-amide oligonucleotide mimic (POM).

scientific article published on April 2001

Label-free screening of bio-molecular interactions.

scientific article

Light-Activated Rhenium Complexes with Dual Mode of Action against Bacteria

scientific article published on 30 January 2020

Lipoamino acids as major components of absorption promoters in drug delivery.

scientific article published on January 2012

Measurement of Drug Lipophilicity and pKa Using Acoustics

scientific article published on 06 March 2012

Mechanism of the regulation of type IB phosphoinositide 3OH-kinase byG-protein betagamma subunits

scientific article published on March 2002

Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin, and maculatin

scientific article

Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First <i>In Vivo</i> Experiments

scientific article published in 2022

Metal complexes as a promising source for new antibiotics

scientific article published on 12 February 2020

Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites

scientific article published on 18 June 2015

Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus.

scientific article

Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A.

scientific article

Mucin Binding Reduces Colistin Antimicrobial Activity.

scientific article

Multi-Institution Research and Education Collaboration Identifies New Antimicrobial Compounds

scientific article published on 26 November 2020

Multifactorial Chromosomal Variants Regulate Polymyxin Resistance In Extensively Drug-Resistant Klebsiella pneumoniae

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.

scientific article published on 9 May 2017

NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.

scientific article published on 14 July 2015

Nanomechanical detection of antibiotic-mucopeptide binding in a model for superbug drug resistance ⬇️

scientific article

Natural product and natural product derived drugs in clinical trials.

scientific article

Natural product libraries: assembly, maintenance, and screening

scientific article

Neutrophils--a key component of ischemia-reperfusion injury

scientific article published on December 2013

Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis.

scientific article published on 27 April 2016

Nitroimidazoles: Molecular Fireworks That Combat a Broad Spectrum of Infectious Diseases.

scientific article

Octapeptin C4 Induces Less Resistance and Novel Mutations in an Epidemic Carbapenemase-producing Klebsiella pneumoniae ST258 Clinical Isolate Compared to Polymyxins

article by Miranda Pitt et al published 28 April 2018 in bioRxiv

Oligonucleotide and Polymer Functionalized Nanoparticles for Amplification-Free Detection of DNA

scientific article published on 30 May 2012

Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation

scientific article published on 03 April 2020

Optical biosensors: where next and how soon?

scientific article published on 19 October 2006

PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome.

scientific article

Pathway-selective antagonism of proteinase activated receptor 2.

scientific article

Piezoelectric sensors based on molecular imprinted polymers for detection of low molecular mass analytes.

scientific article published on 12 October 2007

Plasma Protein Binding Structure-Activity Relationships Related to the N-Terminus of Daptomycin.

scientific article

Positive Frequency Shifts Observed Upon Adsorbing Micron-Sized Solid Objects to a Quartz Crystal Microbalance from the Liquid Phase

scientific article published on 01 March 2010

Probing the reactivity of o-phthalaldehydic acid/methyl ester: synthesis of N-isoindolinones and 3-arylaminophthalides

scientific article published on 01 September 2013

Profiling molecular interactions using label-free acoustic screening

scientific article published on 01 January 2005

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity

scientific article published on August 2016

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

scientific article published on 2 January 2018

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

article

Purification of PaTx-II from the Venom of the Australian King Brown Snake and Characterization of Its Antimicrobial and Wound Healing Activities

scientific article published in 2023

Quantification of NS1 dengue biomarker in serum via optomagnetic nanocluster detection

scientific article

Quantification of Small Molecule-Receptor Affinities and Kinetics by Acoustic Profiling

scientific article published on 01 October 2006

Quantitative detection of staphylococcal enterotoxin B by resonant acoustic profiling.

scientific article published in May 2009

Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus

scientific article published on 2 September 2014

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

scientific article published on 10 June 2016

Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties

scientific article published on 25 July 2017

Resolving biofilm infections: current therapy and drug discovery strategies.

scientific article published on October 2012

Role of the NLRP3 inflammasome in a model of acute burn-induced pain

scientific article

Screening strategies to identify new antibiotics.

scientific article published on March 2012

Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains.

scientific article published in November 2015

Semi-synthesis and NMR spectral assignments of flavonoid and chalcone derivatives

scientific article published on 25 July 2016

Separation and detection of bacteria using rupture event scanning.

scientific article

Short cationic lipopeptides as effective antibacterial agents: Design, physicochemical properties and biological evaluation.

scientific article published on 30 March 2016

Signal transduction profiling using label-free biosensors

scientific article published in January 2009

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli

scientific article

Streaming algorithms for identification of pathogens and antibiotic resistance potential from real-time MinION(TM) sequencing

scientific article published on 26 July 2016

Structure aided design of chimeric antibiotics

article by Tomislav Karoli et al published April 2012 in Bioorganic & Medicinal Chemistry Letters

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.

scientific article published on 23 January 2018

Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-1.

scientific article published on 29 September 2017

Structure-activity relationships for the binding of polymyxins with human α-1-acid glycoprotein

scientific article

Sulfonylureas as Concomitant Insulin Secretagogues and NLRP3 Inflammasome Inhibitors.

scientific article

Surface Ligand Density of Antibiotic-Nanoparticle Conjugates Enhances Target Avidity and Membrane Permeabilization of Vancomycin-Resistant Bacteria.

scientific article

Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.

scientific article

Surface plasmon resonance analysis at a supported lipid monolayer

scientific article published in August 1998

Surface-stress sensors for rapid and ultrasensitive detection of active free drugs in human serum

scientific article published on 2 March 2014

Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two 'old' antibiotics-polymyxin B and chloramphenicol

scientific article

Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents

scientific article published on 01 June 2015

Synthesis of Norbornane Bisether Antibiotics via Silver-mediated Alkylation

scientific article published in January 2015

Synthesis of essramycin and comparison of its antibacterial activity

scientific article published on 4 November 2010

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.

scientific article

The Plasma Protein Binding Proteome of Ertapenem: A Novel Compound-Centric Proteomic Approach for Elucidating Drug-Plasma Protein Binding Interactions.

scientific article published on 28 September 2016

The antigenic architecture of the hemagglutinin of influenza H5N1 viruses ⬇️

scientific article published on August 7, 2013

The changing face of screening and drug discovery

scientific article published on 01 April 2012

The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach

scientific article

The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II.

scientific article published in December 2011

The orientation of the antibiotic peptide maculatin 1.1 in DMPG and DMPC lipid bilayers. Support for a pore-forming mechanism

scientific article published on 01 February 2002

Timed-release polymer nanoparticles

scientific article

Tumor-suppressor Gene Promoter Hypermethylation in Saliva of Head and Neck Cancer Patients

scientific article

Using label-free screening technology to improve efficiency in drug discovery ⬇️

scientific article published on 04 January 2012

Vancomycin dimer formation between analogues of bacterial peptidoglycan surfaces probed by force spectroscopy.

scientific article

Vancomycin: ligand recognition, dimerization and super-complex formation

scientific article

Variation of the net charge, lipophilicity, and side chain flexibility in Dmt(1)-DALDA: Effect on Opioid Activity and Biodistribution

scientific article published on 12 November 2012

Whole genome sequence analysis of the first Australian OXA-48-producing outbreak-associated Klebsiella pneumoniae isolates: the resistome and in vivo evolution

scientific article

Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities

scientific article published on 17 May 2017

α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors.

scientific article

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