List of works by Philip R Taylor

A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation.

scientific article published in August 2011

A targeted disruption of the murine complement factor B gene resulting in loss of expression of three genes in close proximity, factor B, C2, and D17H6S45.

scientific article published in January 1998

Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages

scientific article

Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells

scientific article published on 19 March 2019

Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice

scientific journal article

Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies

scientific article published on May 2003

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.

scientific article

Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells

scientific article published on 4 April 2013

Antigen targeting reveals splenic CD169+ macrophages as promoters of germinal center B-cell responses

scientific article published on 14 January 2015

CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue

scientific article published on 5 February 2015

CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils.

scientific article published on April 2009

Characterisation of murine MICL (CLEC12A) and evidence for an endogenous ligand

scientific article published on April 2008

Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae

scientific article published on 21 January 2011

Cloning of the mouse homolog of the 126-kDa human C1q/MBL/SP-A receptor, C1qR(p)

scientific article (publication date: August 1999)

Complement C3 plays an essential role in the control of opportunistic fungal infections

scientific article published on 06 July 2009

Complement contributes to protective immunity against reinfection by Plasmodium chabaudi chabaudi parasites.

scientific article

Cytosolic phospholipase a2 activation by Candida albicans in alveolar macrophages: role of dectin-1.

scientific article

Dectin-1 is required for beta-glucan recognition and control of fungal infection

scientific article published on 10 December 2006

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

scientific article published on 24 August 2009

Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo

scientific article published on July 2005

Dependence on Dectin-1 Varies With Multiple Candida Species

scientific article published on 06 August 2019

Development and characterization of novel anti-C5 monoclonal antibodies capable of inhibiting complement in multiple species

scientific article published on 17 June 2019

Development of a specific system for targeting protein to metallophilic macrophages

scholarly article

Development of myeloproliferative disease in 12/15-lipoxygenase deficiency

scientific article

Differential dependencies of monocytes and neutrophils on dectin-1, dectin-2 and complement for the recognition of fungal particles in inflammation

scientific article

Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation

scientific article published on January 2013

Effective In Vivo Gene Modification in Mouse Tissue-Resident Peritoneal Macrophages by Intraperitoneal Delivery of Lentiviral Vectors

scientific article published on 18 October 2019

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia

scientific article

Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection

scientific article

Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions

scientific article published on 23 April 2004

Fungal recognition enhances mannose receptor shedding through dectin-1 engagement

scientific article

Hoxb8 conditionally immortalised macrophage lines model inflammatory monocytic cells with important similarity to dendritic cells

scientific article published on 11 January 2011

IL-10 differentially controls the infiltration of inflammatory macrophages and antigen-presenting cells during inflammation

scientific article published on 05 July 2016

In vivo functional analysis and genetic modification of in vitro-derived mouse neutrophils

scientific article published on 2 March 2011

Innate immune response to human bone marrow fibroblastic cell implantation in CB17 scid/beige mice

scientific article published in July 2006

Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages

scientific article published on January 2014

Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction

scientific article published on 30 August 2014

Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology

scientific article published on 12 August 2013

Interleukin-6 signaling drives fibrosis in unresolved inflammation

scientific article published on 09 January 2014

LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells

scientific article

Macrophage Reprogramming for Therapy

scientific article published on 23 December 2020

Monocyte and macrophage heterogeneity

scientific article (publication date: December 2005)

Monocyte heterogeneity and innate immunity.

scientific article published in July 2003

Murine D17H6S45 (Rd) gene: polymorphism and overlap with complement factor B.

scientific article published in October 1997

NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival

scientific article

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

scientific article

Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV.

scientific article published on April 2014

Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation

scientific article published on 10 January 2022

PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease-protective variant PLCγ2 R522

scientific article published on 13 July 2021

Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity

scientific article

Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans

scientific article

Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo

scientific article published in August 2003

Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels

scientific article published on 12 December 2017

Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells

scientific article

Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease

scientific article published on 15 June 2009

RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection

scientific article

Recognition of bacterial capsular polysaccharides and lipopolysaccharides by the macrophage mannose receptor

scientific article

Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor

scientific article published on 3 January 2006

Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin

scientific article

Soluble Dectin-1 as a tool to detect beta-glucans

scientific article published on 23 June 2006

Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis

scientific article

Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells

article

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.

scientific article published on February 2008

Systemic lupus erythematosus, complement deficiency, and apoptosis

scientific article

The C-type lectin SIGNR1 binds Schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infection

scientific article published on 3 November 2008

The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose

scientific article published on 19 January 2006

The contribution of naturally occurring IgM antibodies, IgM cross-reactivity and complement dependency in murine humoral responses to pneumococcal capsular polysaccharides

article

The mannose receptor: linking homeostasis and immunity through sugar recognition

scientific article published in February 2005

The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B.

scientific article

The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors

scientific article published on 26 June 2019

The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal

scientific article

Tissue-resident macrophages

scientific article

Tissue-resident macrophages actively suppress IL-1beta release via a reactive prostanoid/IL-10 pathway

scientific article published on 02 June 2020

Tissue-resident macrophages: then and now.

scientific article

Understanding local macrophage phenotypes in disease: shape-shifting macrophages

scientific article published on February 2015

miR-192 induces G2/M growth arrest in aristolochic acid nephropathy

scientific article

miR-21 Promotes Fibrogenesis in Peritoneal Dialysis

scientific article published on 08 May 2017

Paulina is supported by:

About Paulina

Help