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List of works by Nelson Dusetti

A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT.

scientific article published on 22 July 2016

A subgroup of pancreatic adenocarcinoma is sensitive to the 5-aza-dC DNA methyltransferase inhibitor

scientific article

Absence of tumor suppressor tumor protein 53-induced nuclear protein 1 (TP53INP1) sensitizes mouse thymocytes and embryonic fibroblasts to redox-driven apoptosis

scientific article published on 5 May 2011

Assignment of tumor protein p53 induced nuclear protein 1 (TP53INP1) gene to human chromosome band 8q22 by in situ hybridization.

scientific article

BTN3A is a prognosis marker and a promising target for Vγ9Vδ2 T cells based-immunotherapy in pancreatic ductal adenocarcinoma (PDAC).

scientific article published on 21 September 2017

CDK2 and PKA mediated-sequential phosphorylation is critical for p19INK4d function in the DNA damage response

scientific article

CIP4 is a new ArgBP2 interacting protein that modulates the ArgBP2 mediated control of WAVE1 phosphorylation and cancer cell migration.

scientific article

Cadherin-1 and cadherin-3 cooperation determines the aggressiveness of pancreatic ductal adenocarcinoma

scientific article published on 21 November 2017

Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness

scientific article published on 04 October 2016

Changes in gene expression during pancreatic regeneration: activation of c-myc and H-ras oncogenes in the rat pancreas

scientific article published on 01 March 1991

Changes in growth and pancreatic mRNA concentrations during postnatal development of rat pancreas

scientific article published on 01 July 1990

Changes in pancreatic trophism and gene expression during a prolonged fasting period in rats

scientific journal article

Clinical evaluation of pancreatitis-associated protein as a serum marker of hepatocellular carcinoma: comparison with alpha-fetoprotein

scientific article published on 01 September 1998

Cloning and expression of the mouse PIP49 (Pancreatitis Induced Protein 49) mRNA which encodes a new putative transmembrane protein activated in the pancreas with acute pancreatitis

scientific article published in September 2000

Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation

scientific article

Cloning of IP15, a pancreatitis-induced gene whose expression inhibits cell growth

scientific journal article

Cloning, expression and chromosomal localization of the rat pancreatitis-associated protein III gene

scientific article published on April 1995

Colitis and colitis-associated cancer are exacerbated in mice deficient for tumor protein 53-induced nuclear protein 1.

scientific article published on 22 January 2007

Combined Targeting of G9a and Checkpoint Kinase 1 Synergistically Inhibits Pancreatic Cancer Cell Growth by Replication Fork Collapse

scientific article published on 10 December 2019

Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF

scientific article published on 08 April 2019

Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.

scientific article

Deciphering the cellular source of tumor relapse identifies CD44 as a major therapeutic target in pancreatic adenocarcinoma.

scientific article published on April 2015

Des approches multi-omiques dévoilent de nouvelles cibles thérapeutiques pour le traitement du cancer du pancréas

scientific article published on 01 May 2018

Development of an ELISA detecting Tumor Protein 53-Induced Nuclear Protein 1 in serum of prostate cancer patients

scientific article published on 28 May 2013

Developmental, nutritional, and hormonal regulation of the pancreatitis-associated protein I and III gene expression in the rat small intestine

scientific journal article

Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes.

scientific article

Diurnal changes in actin mRNA levels and incorporation of 35S-methionine into actin in the rat hypothalamus

scientific article published in June 1990

E2F signature is predictive for the pancreatic adenocarcinoma clinical outcome and sensitivity to E2F inhibitors, but not for the response to cytotoxic-based treatments.

scientific article

Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine

scientific article published on 28 August 2019

Evidence of CXC, CC and C chemokine production by lymphatic endothelial cells.

scientific article

Evidencing a pancreatic ductal adenocarcinoma subpopulation sensitive to the proteasome inhibitor Carfilzomib

scientific article published on 15 July 2020

Expression Profiling in Pancreas during the Acute Phase of Pancreatitis Using cDNA Microarrays

scientific article published on 01 November 2000

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer

scientific article published on 20 June 2016

Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts

scientific article published on 08 March 2017

Genetic inactivation of Nupr1 acts as a dominant suppressor event in a two-hit model of pancreatic carcinogenesis.

scientific article published on 11 September 2013

Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach

scientific article

Immunocytochemical localization of pancreatitis-associated protein in human small intestine

scientific article published on 01 March 1995

Induction of lithostathine/reg mRNA expression by serum from rats with acute pancreatitis and cytokines in pancreatic acinar AR-42J cells.

scientific article published on June 1996

Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis

scientific article published on 13 October 2012

Lithostathine, an inhibitor of CaCO3 crystal growth in pancreatic juice, induces bacterial aggregation

scientific article published on 01 September 1993

Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation.

scientific article published on 29 August 2014

Lymphatic endothelial tumors induced by intraperitoneal injection of incomplete Freund's adjuvant.

scientific article published in February 1999

MAGP-1 and fibronectin control EGFL7 functions by driving its deposition into distinct endothelial extracellular matrix locations

scientific article published on 01 November 2018

MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells

scientific article

Meaning of tumor protein 53-induced nuclear protein 1 in the molecular mechanism of gemcitabine sensitivity

scientific article

MicroRNAs in pancreatic ductal adenocarcinoma: new diagnostic and therapeutic clues.

scientific article published on 12 December 2008

Molecular and functional characterization of the stress-induced protein (SIP) gene and its two transcripts generated by alternative splicing. SIP induced by stress and promotes cell death

scientific journal article

Molecular cloning, genomic organization, and chromosomal localization of the human pancreatitis-associated protein (PAP) gene.

scientific article

Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis

scientific article

Novel role of VMP1 as modifier of the pancreatic tumor cell response to chemotherapeutic drugs

scientific article

Optimization of a Bioluminescence Resonance Energy Transfer-Based Assay for Screening of Trypanosoma cruzi Protein/Protein Interaction Inhibitors.

scientific article

Oxidative stress induced by inactivation of TP53INP1 cooperates with KrasG12D to initiate and promote pancreatic carcinogenesis in the murine pancreas

scientific article published on 8 April 2013

Oxidative stress-induced p53 activity is enhanced by a redox-sensitive TP53INP1 SUMOylation

scientific article published on 7 March 2014

P53-dependent expression of the stress-induced protein (SIP).

scientific article

PAP gene transcription induced by cycloheximide in AR4-2J cells involves ADP-ribosylation.

scientific article published on October 1998

PAP, a pancreatic secretory protein induced during acute pancreatitis, is expressed in rat intestine

scientific journal article

PAP/HIP protein is an obesogenic factor

scientific article published on February 2014

Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts

scientific article published in November 2017

Pancreatic Cancer Heterogeneity Can Be Explained Beyond the Genome

scientific article published on 05 April 2019

Prevalence of Microsatellite Instability in Intraductal Papillary Mucinous Neoplasms of the Pancreas

scientific article published on 17 November 2017

Prognostic significance of circulating PD-1, PD-L1, pan-BTN3As, BTN3A1 and BTLA in patients with pancreatic adenocarcinoma

scientific article published on 03 February 2019

Rapid PCR cloning and sequence determination of the rat lithostathine gene.

scientific article published on July 1993

Redox-sensitive TP53INP1 SUMOylation as an oxidative stress sensor to activate TP53.

scientific article published on July 2014

Response to "Is the Reg3α (HIP/PAP) Protein Really an Obesogenic Factor?"

scientific article published on 01 September 2015

Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human T-cell lymphotrophic virus 1

scientific article

Selection of intracellular single-domain antibodies targeting the HIV-1 Vpr protein by cytoplasmic yeast two-hybrid system.

scientific article

Serum from rats with acute pancreatitis induces expression of the PAP mRNA in the pancreatic acinar cell line AR-42J.

scientific article published on October 1994

Speeding towards individualized treatment for pancreatic cancer by taking an alternative road.

scientific article published on 22 September 2017

Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.

scientific article published on 13 February 2013

Stromal SLIT2 impacts on pancreatic cancer-associated neural remodeling

scientific article

Structural organization of the gene encoding the rat pancreatitis-associated protein. Analysis of its evolutionary history reveals an ancient divergence from the other carbohydrate-recognition domain-containing genes.

scientific article published on July 1993

TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma

scientific article published on 3 July 2017

TP53INP1 decreases pancreatic cancer cell migration by regulating SPARC expression

scientific journal article

TP53INP1 overexpression in prostate cancer correlates with poor prognostic factors and is predictive of biological cancer relapse

scientific article published on 2 May 2011

TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death ⬇️

scientific article published on March 16, 2012

TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity.

scientific article

TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling.

scientific article published on 18 April 2015

Targeting CD44 as a novel therapeutic approach for treating pancreatic cancer recurrence.

scientific article published on 15 June 2015

The E3 ubiquitin ligase thyroid hormone receptor-interacting protein 12 targets pancreas transcription factor 1a for proteasomal degradation

scientific article

The SV2 variant of KLF6 is down-regulated in hepatocellular carcinoma and displays anti-proliferative and pro-apoptotic functions.

scientific article published on 23 July 2010

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets

scientific article

The pancreatitis-associated protein I promoter allows targeting to the pancreas of a foreign gene, whose expression is up-regulated during pancreatic inflammation.

scientific article published on February 1997

The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation.

scientific article published on 14 July 2016

The pancreatitis-associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis.

scientific article published on April 1998

The rat genes encoding the pancreatitis-associated proteins I, II and III (Pap1, Pap2, Pap3), and the lithostathin/pancreatic stone protein/regeneration protein (Reg) colocalize at 4q33-->q34

scientific article published on 01 January 1996

Time-dependent effect of melatonin on actin mRNA levels and incorporation of 35S-methionine into actin and proteins by the rat hypothalamus

scientific article published on 01 January 1990

Transcriptomic analysis predicts survival and sensitivity to anticancer drugs of patients with a pancreatic adenocarcinoma

scientific article published on 9 March 2015

Tumor necrosis factor alpha triggers antiapoptotic mechanisms in rat pancreatic cells through pancreatitis-associated protein I activation

scientific journal article

Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development

scientific article

Tumor protein p53-induced nuclear protein (TP53INP1) expression in medullary thyroid carcinoma: a molecular guide to the optimal extent of surgery?

scientific article published on 01 April 2010

Two transcripts are generated from the pancreatitis associated protein II gene by alternative splicing in the 5' untranslated region

scientific article published on 01 April 1995

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