List of works - Alain Goossens

A Dual sgRNA Approach for Functional Genomics in

scientific article published on 31 July 2018

A MYC2/MYC3/MYC4-dependent transcription factor network regulates water spray-responsive gene expression and jasmonate levels

scientific article published on 29 October 2019

A MultiSite Gateway™ vector set for the functional analysis of genes in the model Saccharomyces cerevisiae

scientific article

A Repressor Protein Complex Regulates Leaf Growth in Arabidopsis.

scientific article

A functional genomics approach toward the understanding of secondary metabolism in plant cells

scientific article

A network of stress-related genes regulates hypocotyl elongation downstream of selective auxin perception

scientific article published on 01 September 2021

A rational approach to improving the biotechnological production of taxanes in plant cell cultures of Taxus spp.

scientific article published on 27 March 2014

A single oxidosqualene cyclase produces the seco-triterpenoid α-onocerin

scientific article

A specialized metabolic network selectively modulates Arabidopsis root microbiota

scientific article published on 01 May 2019

A user-friendly platform for yeast two-hybrid library screening using next generation sequencing

scientific article published in PLoS ONE

A widespread alternative squalene epoxidase participates in eukaryote steroid biosynthesis

scientific article published on 26 November 2018

APETALA2/ETHYLENE RESPONSE FACTOR and basic helix-loop-helix tobacco transcription factors cooperatively mediate jasmonate-elicited nicotine biosynthesis

article

An integrated PCR colony hybridization approach to screen cDNA libraries for full-length coding sequences

scientific article

Analysis of RNA-Seq data with TopHat and Cufflinks for genome-wide expression analysis of jasmonate-treated plants and plant cultures

scientific article

Arabidopsis Leaf Flatness Is Regulated by PPD2 and NINJA through Repression of Genes

article

Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro

scientific article published on 14 May 2013

Boosting heterologous protein production in transgenic dicotyledonous seeds using Phaseolus vulgaris regulatory sequences

scientific article published on 4 November 2002

CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway

scientific article published on 01 November 2019

CathaCyc, a metabolic pathway database built from Catharanthus roseus RNA-Seq data

scientific article

Combinatorial biosynthesis in plants: A (p)review on its potential and future exploitation ⬇️

scientific article published on September 28, 2011

Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum

scientific article

Comparative analysis of CYP93E proteins for improved microbial synthesis of plant triterpenoids

scientific article published on 23 October 2014

Coronatine, a more powerful elicitor for inducing taxane biosynthesis in Taxus media cell cultures than methyl jasmonate

article

Determination of saponins in Maesa lanceolata by LC-UV: development and validation

scientific article published on 5 November 2007

Differential transcriptome analysis of glandular and filamentous trichomes in Artemisia annua ⬇️

scientific article

Dissection of the one-MegaDalton JAZ1 protein complex

scientific article published on August 2010

Dissection of the phytohormonal regulation of trichome formation and biosynthesis of the antimalarial compound artemisinin in Artemisia annua plants

scientific article published on 27 September 2010

Evaluation of the anti-angiogenic activity of saponins from Maesa lanceolata by different assays

scientific article published on 01 September 2012

Exploration of jasmonate signalling via automated and standardized transient expression assays in tobacco cells

scientific article published on December 2005

Expression of the Arabidopsis jasmonate signalling repressor JAZ1/TIFY10A is stimulated by auxin

scientific article published on 3 July 2009

FRS7 and FRS12 recruit NINJA to regulate expression of glucosinolate biosynthesis genes

scientific article published on 08 April 2020

Fine-tuning of early events in the jasmonate response

scientific article published on October 2008

Functional characterisation of genes involved in pyridine alkaloid biosynthesis in tobacco

scientific article published on 14 November 2007

Functional specialization of the TRANSPARENT TESTA GLABRA1 network allows differential hormonal control of laminal and marginal trichome initiation in Arabidopsis rosette leaves

scientific article published on 10 September 2008

GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway.

scientific article published on 15 February 2016

Gene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells

scholarly article

Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

scientific article published on 8 August 2016

Hormone-mediated promotion of trichome initiation in plants is conserved but utilizes species- and trichome-specific regulatory mechanisms.

scientific article published on 15 February 2010

Identification of four adenosine kinase isoforms in tobacco By-2 cells and their putative role in the cell cycle-regulated cytokinin metabolism

scientific article

Involvement of Nst1p/YNL091w and Msl1p, a U2B'' splicing factor, in Saccharomyces cerevisiae salt tolerance

scientific article

Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum

scientific article

Iridoid synthase activity is common among the plant progesterone 5β-reductase family

scientific article published on 11 December 2014

It is easy to get huge candidate gene lists for plant metabolism now, but how to get beyond?

scientific article published on 11 December 2014

It's Time for Some "Site"-Seeing: Novel Tools to Monitor the Ubiquitin Landscape in Arabidopsis thaliana

scientific article

Jasmonate and auxin perception: how plants keep F-boxes in check

scientific article published on 01 July 2019

Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco

scientific article

Jasmonate signalling: a copycat of auxin signalling? ⬇️

scientific article published on May 14, 2013

Jasmonate-inducible gene: What does it mean?

scientific article published on 21 January 2009

Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cells

scholarly article

Metabolite profiling of plant tissues by liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry

scientific article published in January 2013

Metabolite profiling of triterpene saponins in Medicago truncatula hairy roots by liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry. ⬇️

scientific article

Methyl jasmonate stimulates the de novo biosynthesis of vitamin C in plant cell suspensions

scientific article published in August 2005

NINJA connects the co-repressor TOPLESS to jasmonate signalling

scientific article

Natural product biosynthesis in Medicago species

scientific article

OSC2 and CYP716A14v2 catalyze the biosynthesis of triterpenoids for the cuticle of aerial organs of Artemisia annua

scientific article published on 9 January 2015

Oleanolic acid.

scientific article

Overexpression of the Arabidopsis thaliana signalling peptide TAXIMIN1 affects lateral organ development

scientific article

Predicting gene function from uncontrolled expression variation among individual wild-type Arabidopsis plants

scientific article published on 13 August 2013

Profiling of the Early Nitrogen Stress Response in the Diatom Phaeodactylum tricornutum Reveals a Novel Family of RING-Domain Transcription Factors

scientific article

Protein-protein and protein-membrane associations in the lignin pathway

scientific article published on 21 November 2012

Quantitation of artemisinin and its biosynthetic precursors in Artemisia annua L. by high performance liquid chromatography-electrospray quadrupole time-of-flight tandem mass spectrometry ⬇️

scientific article published on 2 May 2006

RBR-Type E3 Ligases and the Ubiquitin-Conjugating Enzyme UBC26 Regulate Abscisic Acid Receptor Levels and Signaling

scientific article published on 07 November 2019

Redundancy and specificity in jasmonate signalling

scientific article

Salicylic acid suppresses jasmonic acid signaling downstream of SCFCOI1-JAZ by targeting GCC promoter motifs via transcription factor ORA59

scientific article published on 22 February 2013

Secretion of secondary metabolites by ATP-binding cassette transporters in plant cell suspension cultures

scientific article published in March 2003

Selection and validation of reference genes for transcript normalization in gene expression studies in Catharanthus roseus.

scientific article published on 10 July 2014

Strobilurins as growth-promoting compounds: how Stroby regulates Arabidopsis leaf growth.

scientific article published on 25 April 2017

Synthetic biology approaches for the production of plant metabolites in unicellular organisms

scientific article

Taximin, a conserved plant-specific peptide is involved in the modulation of plant-specialized metabolism.

scientific article published on 23 May 2014

The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses.

scientific article

The MYB transcription factor emission of methyl anthranilate 1 stimulates emission of methyl anthranilate from Medicago truncatula hairy roots

scientific article published on 17 May 2019

The RING E3 Ligase KEEP ON GOING Modulates JASMONATE ZIM-DOMAIN12 Stability.

scientific article published on 28 August 2015

The Ubiquitin System and Jasmonate Signaling

scientific article

The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis

scientific article

The bHLH Transcription Factors TSAR1 and TSAR2 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula

scientific article

The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus.

scientific article published on 15 June 2015

The molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua.

scientific article

The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor

scientific article published on 8 January 2014

The protein quality control system manages plant defence compound synthesis

scientific article published on 10 November 2013

The seco-iridoid pathway from Catharanthus roseus

scientific article published on 07 April 2014

The transcription factor bZIP14 regulates the TCA cycle in the diatom Phaeodactylum tricornutum.

scientific article published on 18 April 2017

The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis.

scientific article

Tracking the sterol biosynthesis pathway of the diatom Phaeodactylum tricornutum

scientific article

Transcript profiling of jasmonate-elicited Taxus cells reveals a β-phenylalanine-CoA ligase.

scientific article published on 21 April 2015

Transcriptional analysis of cell growth and morphogenesis in the unicellular green alga Micrasterias (Streptophyta), with emphasis on the role of expansin

scientific article

Transcriptional machineries in jasmonate-elicited plant secondary metabolism.

scientific article published on 27 March 2012

Transient expression assays in tobacco protoplasts

scientific article

Unraveling the triterpenoid saponin biosynthesis of the African shrub Maesa lanceolata

scientific article published on 11 December 2014

Vacuolar transport of nicotine is mediated by a multidrug and toxic compound extrusion (MATE) transporter in Nicotiana tabacum

scholarly article

Yeast two-hybrid analysis of jasmonate signaling proteins

scientific article published in January 2013

cDNA-AFLP-based transcript profiling for genome-wide expression analysis of jasmonate-treated plants and plant cultures

scientific article published in January 2013

List of works by Alain Goossens

A Dual sgRNA Approach for Functional Genomics in

A MYC2/MYC3/MYC4-dependent transcription factor network regulates water spray-responsive gene expression and jasmonate levels

A MultiSite Gateway™ vector set for the functional analysis of genes in the model Saccharomyces cerevisiae

A Repressor Protein Complex Regulates Leaf Growth in Arabidopsis.

A functional genomics approach toward the understanding of secondary metabolism in plant cells

A network of stress-related genes regulates hypocotyl elongation downstream of selective auxin perception

A rational approach to improving the biotechnological production of taxanes in plant cell cultures of Taxus spp.

A single oxidosqualene cyclase produces the seco-triterpenoid α-onocerin

A specialized metabolic network selectively modulates Arabidopsis root microbiota

A user-friendly platform for yeast two-hybrid library screening using next generation sequencing

A widespread alternative squalene epoxidase participates in eukaryote steroid biosynthesis

APETALA2/ETHYLENE RESPONSE FACTOR and basic helix-loop-helix tobacco transcription factors cooperatively mediate jasmonate-elicited nicotine biosynthesis

An integrated PCR colony hybridization approach to screen cDNA libraries for full-length coding sequences

Analysis of RNA-Seq data with TopHat and Cufflinks for genome-wide expression analysis of jasmonate-treated plants and plant cultures

Arabidopsis Leaf Flatness Is Regulated by PPD2 and NINJA through Repression of Genes

Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro

Boosting heterologous protein production in transgenic dicotyledonous seeds using Phaseolus vulgaris regulatory sequences

CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway

CathaCyc, a metabolic pathway database built from Catharanthus roseus RNA-Seq data

Combinatorial biosynthesis in plants: A (p)review on its potential and future exploitation ⬇️

Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum

Comparative analysis of CYP93E proteins for improved microbial synthesis of plant triterpenoids

Coronatine, a more powerful elicitor for inducing taxane biosynthesis in Taxus media cell cultures than methyl jasmonate

Determination of saponins in Maesa lanceolata by LC-UV: development and validation

Differential transcriptome analysis of glandular and filamentous trichomes in Artemisia annua ⬇️

Dissection of the one-MegaDalton JAZ1 protein complex

Dissection of the phytohormonal regulation of trichome formation and biosynthesis of the antimalarial compound artemisinin in Artemisia annua plants

Evaluation of the anti-angiogenic activity of saponins from Maesa lanceolata by different assays

Exploration of jasmonate signalling via automated and standardized transient expression assays in tobacco cells

Expression of the Arabidopsis jasmonate signalling repressor JAZ1/TIFY10A is stimulated by auxin

FRS7 and FRS12 recruit NINJA to regulate expression of glucosinolate biosynthesis genes

Fine-tuning of early events in the jasmonate response

Functional characterisation of genes involved in pyridine alkaloid biosynthesis in tobacco

Functional specialization of the TRANSPARENT TESTA GLABRA1 network allows differential hormonal control of laminal and marginal trichome initiation in Arabidopsis rosette leaves

GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway.

Gene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells

Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

Hormone-mediated promotion of trichome initiation in plants is conserved but utilizes species- and trichome-specific regulatory mechanisms.

Identification of four adenosine kinase isoforms in tobacco By-2 cells and their putative role in the cell cycle-regulated cytokinin metabolism

Involvement of Nst1p/YNL091w and Msl1p, a U2B'' splicing factor, in Saccharomyces cerevisiae salt tolerance

Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum

Iridoid synthase activity is common among the plant progesterone 5β-reductase family

It is easy to get huge candidate gene lists for plant metabolism now, but how to get beyond?

It's Time for Some "Site"-Seeing: Novel Tools to Monitor the Ubiquitin Landscape in Arabidopsis thaliana

Jasmonate and auxin perception: how plants keep F-boxes in check

Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco

Jasmonate signalling: a copycat of auxin signalling? ⬇️

Jasmonate-inducible gene: What does it mean?

Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cells

Metabolite profiling of plant tissues by liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry

Metabolite profiling of triterpene saponins in Medicago truncatula hairy roots by liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry. ⬇️

Methyl jasmonate stimulates the de novo biosynthesis of vitamin C in plant cell suspensions

NINJA connects the co-repressor TOPLESS to jasmonate signalling

Natural product biosynthesis in Medicago species

OSC2 and CYP716A14v2 catalyze the biosynthesis of triterpenoids for the cuticle of aerial organs of Artemisia annua

Oleanolic acid.

Overexpression of the Arabidopsis thaliana signalling peptide TAXIMIN1 affects lateral organ development

Predicting gene function from uncontrolled expression variation among individual wild-type Arabidopsis plants

Profiling of the Early Nitrogen Stress Response in the Diatom Phaeodactylum tricornutum Reveals a Novel Family of RING-Domain Transcription Factors

Protein-protein and protein-membrane associations in the lignin pathway

Quantitation of artemisinin and its biosynthetic precursors in Artemisia annua L. by high performance liquid chromatography-electrospray quadrupole time-of-flight tandem mass spectrometry ⬇️

RBR-Type E3 Ligases and the Ubiquitin-Conjugating Enzyme UBC26 Regulate Abscisic Acid Receptor Levels and Signaling

Redundancy and specificity in jasmonate signalling

Salicylic acid suppresses jasmonic acid signaling downstream of SCFCOI1-JAZ by targeting GCC promoter motifs via transcription factor ORA59

Secretion of secondary metabolites by ATP-binding cassette transporters in plant cell suspension cultures

Selection and validation of reference genes for transcript normalization in gene expression studies in Catharanthus roseus.

Strobilurins as growth-promoting compounds: how Stroby regulates Arabidopsis leaf growth.

Synthetic biology approaches for the production of plant metabolites in unicellular organisms

Taximin, a conserved plant-specific peptide is involved in the modulation of plant-specialized metabolism.

The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses.

The MYB transcription factor emission of methyl anthranilate 1 stimulates emission of methyl anthranilate from Medicago truncatula hairy roots

The RING E3 Ligase KEEP ON GOING Modulates JASMONATE ZIM-DOMAIN12 Stability.

The Ubiquitin System and Jasmonate Signaling

The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis

The bHLH Transcription Factors TSAR1 and TSAR2 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula

The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus.

The molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua.

The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor

The protein quality control system manages plant defence compound synthesis