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List of works by Sébastien Nisole

A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrict HIV-1.

scholarly article

A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction

scientific article

An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept

scientific article published on 14 July 2016

Anchorage of HIV on permissive cells leads to coaggregation of viral particles with surface nucleolin at membrane raft microdomains.

scientific article

Antiviral properties of two trimeric recombinant gp41 proteins

scientific article published on 3 March 2006

Autochthonous cases of Zika virus in metropolitan France: a new paradigm for this arbovirus ?

scientific article published on 01 December 2019

Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition

scientific article published on 06 November 2019

Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement-A new target for lupus treatment

scientific article published on 10 July 2019

Daxx Inhibits HIV-1 Reverse Transcription and Uncoating in a SUMO-Dependent Manner

scientific article published on 11 June 2020

Differential Roles of PML Isoforms

scientific article published on 22 May 2013

Early steps of retrovirus replicative cycle

scientific article

Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells

scientific article

HIV-1 VPR impairs cell growth through the inactivation of two genetically distinct host cell proteins

article

HIV-derived vectors for therapy and vaccination against HIV.

scientific article published on 13 February 2012

Human TRIM gene expression in response to interferons

scientific article

Hyperthermia stimulates HIV-1 replication

scientific article

Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen

scientific article published on 04 May 2022

Identification of Primary Natural Killer Cell Modulators by Chemical Library Screening with a Luciferase-Based Functional Assay

scientific article published on 05 September 2018

Identification of a small molecule that primes the type I interferon response to cytosolic DNA.

scientific article

Implication of PML nuclear bodies in intrinsic and innate immunity

scientific article published on August 2014

Implication of PMLIV in both intrinsic and innate immunity

scientific article

Implication of TRIM alpha and TRIMCyp in interferon-induced anti-retroviral restriction activities

scientific article published on 9 July 2008

In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication

scientific article published on 06 April 2020

Internal RNA 2′O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect

scientific article published on 10 November 2022

Interplay between SARS-CoV-2 and the type I interferon response

scientific article published on 29 July 2020

Lack of endogenous TRIM5 -mediated restriction in rhesus macaque dendritic cells

scientific article published on 14 August 2008

Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells

scientific article published on 13 October 2019

Modulation of innate immune signaling by a Coxiella burnetii eukaryotic-like effector protein

scientific article published on 01 June 2020

Molecular insight into how HIV-1 Vpr protein impairs cell growth through two genetically distinct pathways.

scientific article published on 12 May 2011

MxA Mediates SUMO-Induced Resistance to Vesicular Stomatitis Virus.

scientific article published on 11 May 2016

MxA interacts with and is modified by the SUMOylation machinery.

scientific article published on 31 October 2014

Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement

scientific article published on 09 February 2017

Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response

scientific article published on 14 August 2017

PML control of cytokine signaling.

scientific article published on 09 May 2014

PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by Daxx

scientific article published on 13 November 2015

RanBP2 regulates the anti-retroviral activity of TRIM5α by SUMOylation at a predicted phosphorylated SUMOylation motif

scientific article published on 15 November 2018

Resistance to Rhabdoviridae Infection and Subversion of Antiviral Responses

scientific article (publication date: July 2015)

Small Ubiquitin-like Modifier Alters IFN Response

scientific article published on 29 July 2015

Sodium arsenite induces apoptosis and Epstein-Barr virus reactivation in lymphoblastoid cells

scientific article published on 21 September 2014

Spontaneous mutations in the env gene of the human immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype.

scientific article published in January 1998

TRIM Protein Family and Viral Restriction

TRIM family proteins: retroviral restriction and antiviral defence

scientific article

TRIM5α is a SUMO substrate

scientific article

TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells

scientific article published on 20 November 2019

The CDK inhibitor p21Cip1/WAF1 is induced by FcgammaR activation and restricts the replication of human immunodeficiency virus type 1 and related primate lentiviruses in human macrophages

scientific article published on 16 September 2009

The Cell-Surface-Expressed Nucleolin Is Associated with the Actin Cytoskeleton

article by Ara G. Hovanessian et al published December 2000 in Experimental Cell Research

The HIV-2 Vpx protein usurps the Cul4A-DDB1-DCAF1 ubiquitin ligase to overcome a post-entry block in macrophage infection

article

The V3 Loop-Mimicking Pseudopeptide 5[K psi(CH2N)PR]- TASP Inhibits HIV Infection in Primary Macrophage Cultures

article

The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptor

scientific article (publication date: 4 October 2002)

The anti-HIV pentameric pseudopeptide HB-19 binds the C-terminal end of nucleolin and prevents anchorage of virus particles in the plasma membrane of target cells

scientific article

The anti-HIV pseudopeptide HB-19 forms a complex with the cell-surface-expressed nucleolin independent of heparan sulfate proteoglycans

scientific article

Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating

scientific article published on 14 October 2019

Trim5alpha protein restricts both HIV-1 and murine leukemia virus

scientific article

Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier

scientific article published on 04 August 2020

[Interferon response: with great power comes great responsibility]

scientific article published on 31 March 2020

[SUMO paralogs and interferon response].

scientific article

[SUMO regulates the capacity of TRIM5α to inhibit HIV-1]

scientific article published on 18 February 2019

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