List of works - Karel Smetana

The miniature pig as an animal model in biomedical research.

scientific article

A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code.

scientific article published on 28 March 2014

Melanoma cells influence the differentiation pattern of human epidermal keratinocytes

scientific article

Upregulation of IL-6, IL-8 and CXCL-1 production in dermal fibroblasts by normal/malignant epithelial cells in vitro: Immunohistochemical and transcriptomic analyses.

scientific article

Smooth muscle actin-expressing stromal fibroblasts in head and neck squamous cell carcinoma: Increased expression of galectin-1 and induction of poor prognosis factors

scientific article published on 09 April 2012

Galectin-3 – an emerging prognostic indicator in advanced head and neck carcinoma

scientific article

Head and neck squamous cancer stromal fibroblasts produce growth factors influencing phenotype of normal human keratinocytes

scientific article published on 19 November 2009

Stromal fibroblasts from basal cell carcinoma affect phenotype of normal keratinocytes

scientific article

Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair

article

Detection of galectin-3 in patients with inflammatory bowel diseases: new serum marker of active forms of IBD?

scientific article published on 7 March 2009

Nuclear presence of adhesion-/growth-regulatory galectins in normal/malignant cells of squamous epithelial origin.

scientific article published on 28 October 2005

Detection of galectin-3 in tear fluid at disease states and immunohistochemical and lectin histochemical analysis in human corneal and conjunctival epithelium.

scientific article

The influence of hydrogel functional groups on cell behavior

scientific article published on 01 April 1990

Multinucleate foreign-body giant cell formation

scientific article published on 01 June 1987

Marker profiling of normal keratinocytes identifies the stroma from squamous cell carcinoma of the oral cavity as a modulatory microenvironment in co-culture

article

Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness

scientific article published on 21 April 2016

Effect of cancer-associated fibroblasts on the migration of glioma cells in vitro

scientific article

Pentadactyl pattern of the avian wing autopodium and pyramid reduction hypothesis.

scientific article

Ageing as an Important Risk Factor for Cancer

scientific article

Porcine epidermal stem cells as a biomedical model for wound healing and normal/malignant epithelial cell propagation

scientific article published on 20 October 2006

Cancer Microenvironment: What Can We Learn from the Stem Cell Niche

scientific article

Defining the glycophenotype of squamous epithelia using plant and mammalian lectins. Differentiation-dependent expression of alpha2,6- and alpha2,3-linked N-acetylneuraminic acid in squamous epithelia and carcinomas, and its differential effect on b

scientific article published in December 2002

Phosphorylated human lectin galectin-3: analysis of ligand binding by histochemical monitoring of normal/malignant squamous epithelia and by isothermal titration calorimetry

scientific article published on 18 October 2008

Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin

scientific article

Effect of Atropa belladonna L. on skin wound healing: biomechanical and histological study in rats and in vitro study in keratinocytes, 3T3 fibroblasts, and human umbilical vein endothelial cells.

scientific article

In vitro fibroblast response to ultra fine grained titanium produced by a severe plastic deformation process

scientific article

Mouse 3T3 fibroblasts under the influence of fibroblasts isolated from stroma of human basal cell carcinoma acquire properties of multipotent stem cells

scientific article published on May 2011

Fibroblasts prepared from different types of malignant tumors stimulate expression of luminal marker keratin 8 in the EM-G3 breast cancer cell line

scientific article published on 24 January 2012

In vitro biocompatibility of equal channel angular processed (ECAP) titanium.

scientific article

Single-site mutational engineering and following monoPEGylation of the human lectin galectin-2: effects on ligand binding, functional aspects, and clearance from serum.

scientific article published on 24 April 2013

Immunocyto- and histochemical profiling of nucleostemin expression: marker of epidermal stem cells?

scientific article

ER-α agonist induces conversion of fibroblasts into myofibroblasts, while ER-β agonist increases ECM production and wound tensile strength of healing skin wounds in ovariectomised rats

scientific article published on 20 April 2011

Cultivation and grafting of human keratinocytes on a poly(hydroxyethyl methacrylate) support to the wound bed: a clinical study

scientific article published on 01 January 1998

Cultivation-dependent plasticity of melanoma phenotype

scientific article published on June 12, 2013

Loss of adhesion/growth-regulatory galectin-9 from squamous cell epithelium in head and neck carcinomas

scientific article

Cancer-associated fibroblasts are not formed from cancer cells by epithelial-to-mesenchymal transition in nu/nu mice

article published in 2014

Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part II. Copolymers with positive and negative charges, polyelectrolyte complexes.

scientific article published in August 2005

Effect of chemical structure of hydrogels on the adhesion and phenotypic characteristics of human monocytes such as expression of galectins and other carbohydrate-binding sites

scientific article published on 01 July 1997

Comparative phenotypic characterization of keratinocytes originating from hair follicles.

scientific article published on February 2005

Emerging role of tissue lectins as microenvironmental effectors in tumors and wounds.

scientific article

Synthetic polyamine BPA-C8 inhibits TGF-β1-mediated conversion of human dermal fibroblast to myofibroblasts and establishment of galectin-1-rich extracellular matrix in vitro

scientific article

Cyclic chalcone analogue KRP6 as a potent modulator of cell proliferation: an in vitro study in HUVECs.

scientific article published on 11 May 2013

Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part III. Hydrogels as carriers for immobilization of proteins.

scientific article published in August 2005

Physicochemical aspects of the giant multinucleate cell formation

scientific article published on 01 October 1987

Mannosides as crucial part of bioactive supports for cultivation of human epidermal keratinocytes without feeder cells

scientific article published on February 2003

Genome-wide Expression Profiling (with Focus on the Galectin Network) in Tumor, Transition Zone and Normal Tissue of Head and Neck Cancer: Marked Differences Between Individual Patients and the Site of Specimen Origin

scientific article published in May 2017

Reconstruction of epidermis by grafting of keratinocytes cultured on polymer support--clinical study.

scientific article published on March 2003

Diagnostic relevance of Langerin detection in cells from bronchoalveolar lavage of patients with pulmonary Langerhans cell histiocytosis, sarcoidosis and idiopathic pulmonary fibrosis

scientific article

Intraocular biocompatibility of hydroxyethyl methacrylate and methacrylic acid copolymer/partially hydrolyzed poly(2-hydroxyethyl methacrylate).

scientific article published in October 1987

Functional differences between neonatal and adult fibroblasts and keratinocytes: Donor age affects epithelial-mesenchymal crosstalk in vitro

scientific article published on 11 August 2016

List of works by Karel Smetana

The miniature pig as an animal model in biomedical research.

A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code.

Melanoma cells influence the differentiation pattern of human epidermal keratinocytes

Upregulation of IL-6, IL-8 and CXCL-1 production in dermal fibroblasts by normal/malignant epithelial cells in vitro: Immunohistochemical and transcriptomic analyses.

Smooth muscle actin-expressing stromal fibroblasts in head and neck squamous cell carcinoma: Increased expression of galectin-1 and induction of poor prognosis factors

Galectin-3 – an emerging prognostic indicator in advanced head and neck carcinoma

Head and neck squamous cancer stromal fibroblasts produce growth factors influencing phenotype of normal human keratinocytes

Stromal fibroblasts from basal cell carcinoma affect phenotype of normal keratinocytes

Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair

Detection of galectin-3 in patients with inflammatory bowel diseases: new serum marker of active forms of IBD?

Nuclear presence of adhesion-/growth-regulatory galectins in normal/malignant cells of squamous epithelial origin.

Detection of galectin-3 in tear fluid at disease states and immunohistochemical and lectin histochemical analysis in human corneal and conjunctival epithelium.

The influence of hydrogel functional groups on cell behavior

Multinucleate foreign-body giant cell formation

Marker profiling of normal keratinocytes identifies the stroma from squamous cell carcinoma of the oral cavity as a modulatory microenvironment in co-culture

Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness

Effect of cancer-associated fibroblasts on the migration of glioma cells in vitro

Pentadactyl pattern of the avian wing autopodium and pyramid reduction hypothesis.

Ageing as an Important Risk Factor for Cancer

Porcine epidermal stem cells as a biomedical model for wound healing and normal/malignant epithelial cell propagation

Cancer Microenvironment: What Can We Learn from the Stem Cell Niche

Defining the glycophenotype of squamous epithelia using plant and mammalian lectins. Differentiation-dependent expression of alpha2,6- and alpha2,3-linked N-acetylneuraminic acid in squamous epithelia and carcinomas, and its differential effect on b

Phosphorylated human lectin galectin-3: analysis of ligand binding by histochemical monitoring of normal/malignant squamous epithelia and by isothermal titration calorimetry

Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin

Effect of Atropa belladonna L. on skin wound healing: biomechanical and histological study in rats and in vitro study in keratinocytes, 3T3 fibroblasts, and human umbilical vein endothelial cells.

In vitro fibroblast response to ultra fine grained titanium produced by a severe plastic deformation process

Mouse 3T3 fibroblasts under the influence of fibroblasts isolated from stroma of human basal cell carcinoma acquire properties of multipotent stem cells

Fibroblasts prepared from different types of malignant tumors stimulate expression of luminal marker keratin 8 in the EM-G3 breast cancer cell line

In vitro biocompatibility of equal channel angular processed (ECAP) titanium.

Single-site mutational engineering and following monoPEGylation of the human lectin galectin-2: effects on ligand binding, functional aspects, and clearance from serum.

Immunocyto- and histochemical profiling of nucleostemin expression: marker of epidermal stem cells?

ER-α agonist induces conversion of fibroblasts into myofibroblasts, while ER-β agonist increases ECM production and wound tensile strength of healing skin wounds in ovariectomised rats

Cultivation and grafting of human keratinocytes on a poly(hydroxyethyl methacrylate) support to the wound bed: a clinical study

Cultivation-dependent plasticity of melanoma phenotype

Loss of adhesion/growth-regulatory galectin-9 from squamous cell epithelium in head and neck carcinomas

Cancer-associated fibroblasts are not formed from cancer cells by epithelial-to-mesenchymal transition in nu/nu mice

Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part II. Copolymers with positive and negative charges, polyelectrolyte complexes.

Effect of chemical structure of hydrogels on the adhesion and phenotypic characteristics of human monocytes such as expression of galectins and other carbohydrate-binding sites

Comparative phenotypic characterization of keratinocytes originating from hair follicles.

Emerging role of tissue lectins as microenvironmental effectors in tumors and wounds.

Synthetic polyamine BPA-C8 inhibits TGF-β1-mediated conversion of human dermal fibroblast to myofibroblasts and establishment of galectin-1-rich extracellular matrix in vitro

Cyclic chalcone analogue KRP6 as a potent modulator of cell proliferation: an in vitro study in HUVECs.

Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part III. Hydrogels as carriers for immobilization of proteins.

Physicochemical aspects of the giant multinucleate cell formation

Mannosides as crucial part of bioactive supports for cultivation of human epidermal keratinocytes without feeder cells

Genome-wide Expression Profiling (with Focus on the Galectin Network) in Tumor, Transition Zone and Normal Tissue of Head and Neck Cancer: Marked Differences Between Individual Patients and the Site of Specimen Origin

Reconstruction of epidermis by grafting of keratinocytes cultured on polymer support--clinical study.

Diagnostic relevance of Langerin detection in cells from bronchoalveolar lavage of patients with pulmonary Langerhans cell histiocytosis, sarcoidosis and idiopathic pulmonary fibrosis

Intraocular biocompatibility of hydroxyethyl methacrylate and methacrylic acid copolymer/partially hydrolyzed poly(2-hydroxyethyl methacrylate).

Functional differences between neonatal and adult fibroblasts and keratinocytes: Donor age affects epithelial-mesenchymal crosstalk in vitro