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List of works by Karel Smetana

A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code.

scientific article published on 28 March 2014

Abstract B26: Melanoma cells induce stem cells like fenotype of normal human keratinocytes

Ageing as an Important Risk Factor for Cancer

scientific article

Analysis of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas and Paired Normal Mucosae Reveals Cyclin D1 Deregulation and Compensatory Effect of Cyclin D2

scientific article published on 26 March 2020

Analysis of binding of mannosides in relation to Langerin (CD207) in Langerhans cells of normal and transformed epithelia

scientific article published in May 2002

Analysis of dermal fibroblasts isolated from neonatal and child cleft lip and adult skin: Developmental implications on reconstructive surgery.

scientific article published on 7 September 2017

Biological and biochemical properties of the carbon composite and polyethylene implant materials

scientific article published on 01 June 2003

Biological properties of copolymer of 2-hydroxyethyl methacrylate with sulfopropyl methacrylate

scientific article published on July 2001

Biological properties of the intervertebral cages made of titanium containing a carbon-carbon composite covered with different polymers.

scientific article published in February 2005

Brain lesion-induced alteration of selected phenotypic properties of spleen macrophages and their partial restoration in the course of foreign body reaction against intraperitoneally implanted polymers

scientific article published on 01 July 1999

Cancer Microenvironment: What Can We Learn from the Stem Cell Niche

scientific article

Cancer-associated fibroblasts are not formed from cancer cells by epithelial-to-mesenchymal transition in nu/nu mice

article published in 2014

Comparative phenotypic characterization of keratinocytes originating from hair follicles.

scientific article published on February 2005

Comparative study of human monocyte and platelet adhesion to hydrogels in vitro - effect of polymer structure

scientific article published on 01 January 1997

Craniopharyngioma: a case report and comparative galectin histochemical analysis.

scientific article published on March 2002

Cultivation and grafting of human keratinocytes on a poly(hydroxyethyl methacrylate) support to the wound bed: a clinical study

scientific article published on 01 January 1998

Cultivation of human keratinocytes without feeder cells on polymer carriers containing ethoxyethyl methacrylate: in vitro study.

scientific article published in August 2007

Cultivation-dependent plasticity of melanoma phenotype

scientific article published on 12 June 2013

Cyclic chalcone analogue KRP6 as a potent modulator of cell proliferation: an in vitro study in HUVECs.

scientific article published on 11 May 2013

Decrease of nuclear reactivity to growth-regulatory galectin-1 in senescent human keratinocytes and detection of non-uniform staining profile alterations upon prolonged culture for galectin-1 and -3.

scientific article published on December 2004

Defining the glycophenotype of squamous epithelia using plant and mammalian lectins. Differentiation-dependent expression of alpha2,6- and alpha2,3-linked N-acetylneuraminic acid in squamous epithelia and carcinomas, and its differential effect on b

scientific article published in December 2002

Detection of Distinct Changes in Gene-expression Profiles in Specimens of Tumors and Transition Zones of Tenascin-positive/-negative Head and Neck Squamous Cell Carcinoma

scientific article published on 01 March 2018

Detection of cell type and marker specificity of nuclear binding sites for anionic carbohydrate ligands.

scientific article published on June 2004

Detection of galectin-3 in patients with inflammatory bowel diseases: new serum marker of active forms of IBD?

scientific article published on 7 March 2009

Detection of galectin-3 in tear fluid at disease states and immunohistochemical and lectin histochemical analysis in human corneal and conjunctival epithelium.

scientific article

Diagnostic relevance of Langerin detection in cells from bronchoalveolar lavage of patients with pulmonary Langerhans cell histiocytosis, sarcoidosis and idiopathic pulmonary fibrosis

scientific article

Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin

scientific article

Dolichos biflorus agglutinin-binding site expression in basal keratinocytes is associated with cell differentiation

scientific article published on October 2002

ER-α agonist induces conversion of fibroblasts into myofibroblasts, while ER-β agonist increases ECM production and wound tensile strength of healing skin wounds in ovariectomised rats.

scientific article published on 20 April 2011

Ecology of melanoma cell

scientific article published on 29 August 2017

Effect of Atropa belladonna L. on skin wound healing: biomechanical and histological study in rats and in vitro study in keratinocytes, 3T3 fibroblasts, and human umbilical vein endothelial cells.

scientific article

Effect of cancer-associated fibroblasts on the migration of glioma cells in vitro

scientific article

Effect of chemical structure of hydrogels on the adhesion and phenotypic characteristics of human monocytes such as expression of galectins and other carbohydrate-binding sites

scientific article published on 01 July 1997

Effect of phagocytosis of pHEMA particles and of heat-killed Candida albicans on expression of carbohydrate-binding sites such as endogenous lectins in phagocytes

scientific article published on 01 April 1996

Emerging role of tissue lectins as microenvironmental effectors in tumors and wounds.

scientific article

Evaluation of biocompatibility of the copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate

scientific article published in January 2002

Fibroblasts prepared from different types of malignant tumors stimulate expression of luminal marker keratin 8 in the EM-G3 breast cancer cell line

scientific article published on 24 January 2012

Foreign body reaction against cellophane in the athymic nude mice

scientific article published on 01 August 1989

Functional differences between neonatal and adult fibroblasts and keratinocytes: Donor age affects epithelial-mesenchymal crosstalk in vitro

scientific article published on 11 August 2016

Fusion of macrophages on an implant surface is associated with down-regulated expression of ligands for galectin-1 and -3 in the rat

scientific article published on 01 October 1998

Galectin-3 – an emerging prognostic indicator in advanced head and neck carcinoma

scientific article

Galectin-3, an endogenous lectin, as a tool for monitoring cell differentiation in head and neck carcinomas with implications for lectin-glycan functionality

scientific article published on 01 January 2003

Genome-wide Expression Profiling (with Focus on the Galectin Network) in Tumor, Transition Zone and Normal Tissue of Head and Neck Cancer: Marked Differences Between Individual Patients and the Site of Specimen Origin

scientific article published in May 2017

Glycobiology of head and neck squamous epithelia and carcinomas

scientific article

Head and neck squamous cancer stromal fibroblasts produce growth factors influencing phenotype of normal human keratinocytes

scientific article published on 19 November 2009

How Signaling Molecules Regulate Tumor Microenvironment: Parallels to Wound Repair

scientific article

Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair

article

IL-6 in the Ecosystem of Head and Neck Cancer: Possible Therapeutic Perspectives

scientific article published on 14 October 2021

Immunocyto- and histochemical profiling of nucleostemin expression: marker of epidermal stem cells?

scientific article

Implantation of p(HEMA)-collagen composite into bone

scientific article published on 01 January 1992

In vitro biocompatibility of equal channel angular processed (ECAP) titanium.

scientific article

In vitro fibroblast response to ultra fine grained titanium produced by a severe plastic deformation process

scientific article

Influence of carboxylate ions containing polymers on calcification: in vitro study

scientific article published on 01 August 1996

Influence of intraperitoneal injection of three types of hydrogel beads on expression of carbohydrate-binding sites in spleen macrophages

scientific article published on 01 December 1996

Intercellular crosstalk in human malignant melanoma

scientific article

Interleukin-6: Molecule in the Intersection of Cancer, Ageing and COVID-19

scientific article published on 26 October 2020

Intraocular biocompatibility of hydroxyethyl methacrylate and methacrylic acid copolymer/partially hydrolyzed poly(2-hydroxyethyl methacrylate).

scientific article published in October 1987

Loss of adhesion/growth-regulatory galectin-9 from squamous cell epithelium in head and neck carcinomas

scientific article

Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part II. Copolymers with positive and negative charges, polyelectrolyte complexes.

scientific article published in August 2005

Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part III. Hydrogels as carriers for immobilization of proteins.

scientific article published in August 2005

Mannosides as crucial part of bioactive supports for cultivation of human epidermal keratinocytes without feeder cells

scientific article published on February 2003

Mapping of endogenous lectins in macrophages colonizing an implanted polymer surface--effect of polymer structure

scientific article published on 01 October 1995

Marker profiling of normal keratinocytes identifies the stroma from squamous cell carcinoma of the oral cavity as a modulatory microenvironment in co-culture

article

Melanoma cells influence the differentiation pattern of human epidermal keratinocytes

scientific article

Microarray analysis of serum mRNA in patients with head and neck squamous cell carcinoma at whole-genome scale

scientific article

Microenvironment‑driven resistance to B‑Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts

scientific article published in February 2018

Mouse 3T3 fibroblasts under the influence of fibroblasts isolated from stroma of human basal cell carcinoma acquire properties of multipotent stem cells

scientific article published on May 2011

Multinucleate foreign-body giant cell formation

scientific article published on 01 June 1987

Nuclear presence of adhesion-/growth-regulatory galectins in normal/malignant cells of squamous epithelial origin.

scientific article published on 28 October 2005

Pentadactyl pattern of the avian wing autopodium and pyramid reduction hypothesis.

scientific article

Phenotypic characterization of human keratinocytes in coculture reveals differential effects of fibroblasts from benign fibrous histiocytoma (dermatofibroma) as compared to cells from its malignant form and to normal fibroblasts

scientific article published on 2 May 2009

Phenotypic characterization of keratinocytes migrated from polymer support - in vitro study.

scientific article published on October 1997

Phenotypic characterization of oral mucosa: what is normal?

scientific article

Phosphorylated human lectin galectin-3: analysis of ligand binding by histochemical monitoring of normal/malignant squamous epithelia and by isothermal titration calorimetry

scientific article published on 18 October 2008

Physicochemical aspects of the giant multinucleate cell formation

scientific article published on 01 October 1987

Plantago lanceolata L. water extract induces transition of fibroblasts into myofibroblasts and increases tensile strength of healing skin wounds

scientific article published on 22 September 2014

Poly(HEMA)-collagen composite as a biomaterial for hard tissue replacement

scientific article

Porcine epidermal stem cells as a biomedical model for wound healing and normal/malignant epithelial cell propagation

scientific article published on 20 October 2006

Postmitotic basal cells in squamous cell epithelia are identified with Dolichos biflorus agglutinin--functional consequences.

scientific article

Preparation of poly(2-hydroxyethyl methacrylate)-collagen composites

scientific article published on 01 January 1993

Reconstruction of epidermis by grafting of keratinocytes cultured on polymer support--clinical study.

scientific article published on March 2003

Revelation of fibroblast protein commonalities and differences and their possible roles in wound healing and tumourigenesis using co-culture models of cells.

scientific article published on 26 May 2014

Silicone rubber-hydrogel composites as polymeric biomaterials. IX. Composites containing powdery polyacrylamide hydrogel.

scientific article

Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness

scientific article published on 21 April 2016

Single-Cell RNA Sequencing Unravels Heterogeneity of the Stromal Niche in Cutaneous Melanoma Heterogeneous Spheroids

scientific article published on 10 November 2020

Single-site mutational engineering and following monoPEGylation of the human lectin galectin-2: effects on ligand binding, functional aspects, and clearance from serum.

scientific article published on 24 April 2013

Smooth muscle actin-expressing stromal fibroblasts in head and neck squamous cell carcinoma: Increased expression of galectin-1 and induction of poor prognosis factors

scientific article published on 09 April 2012

Stromal fibroblasts from basal cell carcinoma affect phenotype of normal keratinocytes

scientific article

Structure and biocompatibility of ion beam modified polyethylene

scientific article published on 01 July 1997

Study of laser created ZRO2 and hydroxyapatite/ZrO2 films for implantology.

scientific article

Synthetic polyamine BPA-C8 inhibits TGF-β1-mediated conversion of human dermal fibroblast to myofibroblasts and establishment of galectin-1-rich extracellular matrix in vitro

scientific article

Targeted Therapies for Melanoma

scientific article published on 03 September 2020

The Head and Neck Squamous Cell Carcinoma Microenvironment as a Potential Target for Cancer Therapy

scientific article published on 28 March 2019

The influence of hydrogel functional groups on cell behavior

scientific article published on 01 April 1990

The miniature pig as an animal model in biomedical research.

scientific article

Tumor Biology and Microenvironment of Vestibular Schwannoma-Relation to Tumor Growth and Hearing Loss

scientific article published in 2022

Upregulation of IL-6, IL-8 and CXCL-1 production in dermal fibroblasts by normal/malignant epithelial cells in vitro: Immunohistochemical and transcriptomic analyses.

scientific article

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