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List of works by Pau Castel

A novel vascular tumor characterized by co-existing HRAS and GNAQ activating mutations

scientific article published on 13 December 2018

Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer

scientific article

Chromatin accessibility landscape and active transcription factors in primary human invasive lobular and ductal breast carcinomas

scientific article published in 2022

Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor

scientific article

Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs

scientific article published on 25 April 2022

Data from Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation

Data from Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation

DoMY-Seq: A yeast two-hybrid-based technique for precision mapping of protein-protein interaction motifs

scientific article published on 03 November 2020

Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition

scientific article published on 12 April 2021

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition

scientific journal article

PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer

scientific article published on April 2015

PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D.

scientific article

PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.

scientific article published on 24 October 2016

RIT1 oncoproteins escape LZTR1-mediated proteolysis

scientific article published on 01 March 2019

Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment

scientific article published on July 2014

Somatic PIK3CA mutations as a driver of sporadic venous malformations.

scientific article published on March 2016

Supplementary Figure from Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation

Supplementary Figure from Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation

Systematic Functional Characterization of Resistance to PI3K Inhibition in Breast Cancer

scientific article published on 7 September 2016

The duality of human oncoproteins: drivers of cancer and congenital disorders

scientific article published on 27 April 2020

The emerging role of serum/glucocorticoid-regulated kinases in cancer

scientific article published on 16 September 2016

The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth

scientific article published on October 2016

The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth

scientific article published on August 2016

The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium

scientific article published on 26 January 2016

Therapeutic Benefit of Selective Inhibition of p110α PI3-Kinase in Pancreatic Neuroendocrine Tumors

scientific article

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