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List of works by Pedro M. Persechini

A cation non-selective channel induced by extracellular ATP in macrophages and phagocytic cells of the thymic reticulum

scientific article published on 01 January 1996

ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages

scientific journal article

ATP induces the death of developing avian retinal neurons in culture via activation of P2X7 and glutamate receptors.

scientific article published on 26 June 2012

ATP- and UTP-induced currents in macrophages and macrophage polykaryons

scientific article published on 01 December 1993

ATP-induced P2X7-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages.

scientific article published on 9 September 2008

ATP-induced apoptosis involves a Ca2+-independent phospholipase A2 and 5-lipoxygenase in macrophages

scientific article

Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation.

scientific article published on February 2006

Apoptosis-inducing factor of a cytotoxic T cell line: involvement of a secretory phospholipase A2.

scientific article published on 27 January 2006

Channel-forming activity of the perforin N-terminus and a putative alpha-helical region homologous with complement C9.

scientific article published in June 1992

Characterization of P2 receptors in thymic epithelial cells.

scientific article published on February 2001

Characterization of P2Z purinergic receptors on phagocytic cells of the thymic reticulum in culture

scientific article published in April 1996

Characterization of recombinant mouse perforin expressed in insect cells using the baculovirus system

scientific article published on May 1994

Cytolytic and ion channel-forming properties of the N terminus of lymphocyte perforin

scientific article published on June 1, 1991

Cytoplasts from cytotoxic T lymphocytes are resistant to perforin-mediated lysis

scientific article published in September 1991

Differential modulation of ATP-induced P2X7-associated permeabilities to cations and anions of macrophages by infection with Leishmania amazonensis.

scientific article

Differential susceptibility of type III erythrocytes of paroxysmal nocturnal hemoglobinuria to lysis mediated by complement and perforin

scientific article published on 01 July 1989

Distinct kinetics of effector CD8+ cytotoxic T cells after infection with Trypanosoma cruzi in naive or vaccinated mice.

scientific article published in April 2006

Effect of extracellular ATP on the human leukaemic cell line K562 and its multidrug counterpart.

scientific article published on 6 July 2006

Electrophysiology of phagocytic membranes. II. Membrane potential and induction of slow hyperpolarizations in activated macrophages

scientific article published on April 4, 1979

Electrophysiology of phagocytic membranes. Role of divalent cations in membrane hyperpolarizations of macrophage polykaryons

scientific article published on 01 April 1986

Electrophysiology of phagocytic membranes: induction of slow membrane hyperpolarizations in macrophages and macrophage polykaryons by intracellular calcium injection

scientific article published on 01 January 1981

Electrophysiology of phagocytic membranes: intracellular K+ activity and K+ equilibrium potential in macrophage polykaryons

scientific article published in May 1987

Evidence for a perforin-mediated mechanism controlling cardiac inflammation in Trypanosoma cruzi infection

scientific article published in April 2002

Expression and characterization of functionally active recombinant perforin produced in insect cells

scientific article published on May 1996

Expression of purinergic receptors and modulation of P2X7 function by the inflammatory cytokine IFNgamma in human epithelial cells.

scientific article published on 21 March 2009

Extracellular ATP in the lymphohematopoietic system: P2Z purinoceptors off membrane permeabilization

scientific article

Extracellular ATP induces cell death in CD4+/CD8+ double-positive thymocytes in mice infected with Trypanosoma cruzi.

scientific article published in December 2003

Heterogeneity of granules of murine cytolytic T lymphocytes. Isolation of a homogeneous population of dense granules

scientific article published on 01 November 1989

In vivo expression of perforin by CD8+ lymphocytes in autoimmune disease. Studies on spontaneous and adoptively transferred diabetes in nonobese diabetic mice

scientific article

Inhibitors of the 5-lipoxygenase arachidonic acid pathway induce ATP release and ATP-dependent organic cation transport in macrophages

scientific article published on 15 April 2014

Membrane channel formation by the lymphocyte pore-forming protein: comparison between susceptible and resistant target cells

scientific article published on June 1, 1990

Modulation of CD4(+) T cell-dependent specific cytotoxic CD8(+) T cells differentiation and proliferation by the timing of increase in the pathogen load

scientific article

Modulation of P2X(7) purinergic receptor in macrophages by Leishmania amazonensis and its role in parasite elimination.

scientific article published on 09 May 2009

Modulation of P2X7 receptor expression in macrophages from mineral oil-injected mice

scientific article published on 4 January 2008

Modulation of P2Z/P2X(7) receptor activity in macrophages infected with Chlamydia psittaci.

scientific article

Modulation of extracellular matrix components by metalloproteinases and their tissue inhibitors during degeneration and regeneration of rat sural nerve

scientific article published on 6 October 2006

Modulation of intercellular communication in macrophages: possible interactions between GAP junctions and P2 receptors

scientific journal article

Molecular mechanisms of lymphocyte-mediated killing.

scientific article published on January 1988

Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages

scientific journal article

P2X7 modulatory web in Trypanosoma cruzi infection

scientific article published on 8 July 2008

P2Z purinoceptor-associated pores induced by extracellular ATP in macrophages and J774 cells

scientific article published on December 1, 1997

P2Z/P2X7 receptor-dependent apoptosis of dendritic cells

scientific article published on 01 May 1999

Perforin and gamma interferon expression are required for CD4+ and CD8+ T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by heterologous plasmid DNA prime-recombinant adenovirus 5 boost vaccination.

scientific article published on 03 August 2009

Perforin and lymphocyte-mediated cytolysis.

scientific article published on August 1995

Regulation of extracellular ATP in human erythrocytes infected with Plasmodium falciparum

scientific article

Resistance of cytolytic lymphocytes to perforin-mediated killing. Inhibition of perforin binding activity by surface membrane proteins

scientific article published on 01 February 1990

Resistance of cytolytic lymphocytes to perforin-mediated killing. Lack of correlation with complement-associated homologous species restriction.

scientific article

Resistance of cytolytic lymphocytes to perforin-mediated killing. Murine cytotoxic T lymphocytes and human natural killer cells do not contain functional soluble homologous restriction factor or other specific soluble protective factors

scientific article published on 01 September 1989

Resistance to the pore-forming protein of cytotoxic T cells: comparison of target cell membrane rigidity.

scientific article published on September 1990

Stage-specific distinctions in potassium channel blocker control of T-lymphocyte activation

scientific article published on 01 January 1988

Structural and functional identification of GP57/51 antigen of Trypanosoma cruzi as a cysteine proteinase

scientific article published on 01 November 1990

The P2Z purinoceptor: an open question in the immune system

scientific article published on 01 June 1996

The distribution of perforin in normal tissues.

scientific article published on June 1991

The lymphocyte pore-forming protein perforin is associated with granules by a pH-dependent mechanism

scientific article

The primary structure of the lymphocyte pore-forming protein perforin: partial amino acid sequencing and determination of isoelectric point

scientific article published on 01 October 1988

The role of purinergic P2X7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice

scientific journal article

What is going on with natural killer cells in HIV infection?

scientific article published on 17 March 2004