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List of works by Nicholas D. Holliday

A G protein-coupled receptor dimer imaging assay reveals selectively modified pharmacology of neuropeptide Y Y1/Y5 receptor heterodimers

scientific article published on 30 January 2015

A functional comparison of recombinant and native somatostatin sst2 receptor variants in epithelia.

scientific article

Application of fluorescence correlation spectroscopy to study substrate binding in styrene maleic acid lipid copolymer encapsulated ABCG2

scientific article published on 11 February 2020

Biased Gs versus Gq proteins and β-arrestin signaling in the NK1 receptor determined by interactions in the water hydrogen bond network

scientific article published on 12 August 2015

Bimolecular fluorescence complementation: lighting up seven transmembrane domain receptor signalling networks

scientific article

Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer

scientific article

Common structural basis for constitutive activity of the ghrelin receptor family

scientific article

Constitutive neuropeptide Y Y(4) receptor expression in human colonic adenocarcinoma cell lines

scientific article

Control of signalling efficacy by palmitoylation of the rat Y1 receptor

scientific article published on June 2003

Deciphering the complex three-way interaction between the non-integrin laminin receptor, galectin-3 and Neisseria meningitidis.

scientific article published on October 2014

Differential signaling by splice variants of the human free fatty acid receptor GPR120.

scientific article published on 26 January 2012

Dimer formation and conformational flexibility ensure cytoplasmic stability and nuclear accumulation of Elk-1

scientific article published on 4 May 2011

Dimerization of ABCG2 analysed by bimolecular fluorescence complementation

scientific article

Dissecting the pharmacology of G protein-coupled receptor signaling complexes using bimolecular fluorescence complementation.

scientific article published on January 2012

Drug discovery opportunities and challenges at g protein coupled receptors for long chain free Fatty acids

scientific article published on January 2011

Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors

scientific article published on 2 October 2017

Fluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity

scientific article published on 19 November 2019

Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane mobility of neuropeptide Y receptors

scientific article

Functionally biased signalling properties of 7TM receptors - opportunities for drug development for the ghrelin receptor

scientific article published on December 2013

Identification of a Cyanine-Dye Labeled Peptidic Ligand for Y1R and Y4R, Based upon the Neuropeptide Y C-Terminal Analogue, BVD-15.

scientific article published on 11 August 2016

Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor

scientific article published on 23 August 2007

Inhibition of cyclic AMP-dependent chloride secretion by PP receptors and alpha 2-adrenoceptors in a human colonic epithelial cell line.

scientific article published on February 1997

Modulation of chloride, potassium and bicarbonate transport by muscarinic receptors in a human adenocarcinoma cell line.

scientific article published on January 1999

Optically Pure, Structural, and Fluorescent Analogues of a Dimeric Y4 Receptor Agonist Derived by an Olefin Metathesis Approach.

scientific article published on 13 June 2016

Plasma membrane dynamics and tetrameric organisation of ABCG2 transporters in mammalian cells revealed by single particle imaging techniques

scientific article published on 7 October 2015

Quantitative analysis of neuropeptide Y receptor association with beta-arrestin2 measured by bimolecular fluorescence complementation.

scientific article

Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M2 Receptor

scientific article published on 01 April 2020

Role of the C terminus in neuropeptide Y Y1 receptor desensitization and internalization

scientific article

Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119.

scientific article published on December 2014

Synthetic routes to the Neuropeptide Y Y1 receptor antagonist 1229U91 and related analogues for SAR studies and cell-based imaging.

scientific article published on 14 April 2014

The Peptide PnPP-19, a Spider Toxin Derivative, Activates μ-Opioid Receptors and Modulates Calcium Channels.

scientific article published on 15 January 2018

The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor

scientific article published on 26 July 2012

The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex

scientific article published on 28 February 2020

Unique interaction pattern for a functionally biased ghrelin receptor agonist

scientific article published on 14 March 2011

Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data

scientific article

Y(4) receptors mediate the inhibitory responses of pancreatic polypeptide in human and mouse colon mucosa

scientific article

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