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List of works by Raquel Sá-Leão

Ability of Antibiotic-Resistant Nonvaccine-Type Pneumococcal Clones to Cause Otitis Media in an Infant Mouse Model of Pneumococcal-Influenza Virus Coinfection

scientific article published on 14 September 2015

Analysis of invasiveness of pneumococcal serotypes and clones circulating in Portugal before widespread use of conjugate vaccines reveals heterogeneous behavior of clones expressing the same serotype. ⬇️

scientific article published on 26 January 2011

Carriage and antibiotic resistance of respiratory pathogens and molecular epidemiology of antibiotic-resistant Streptococcus pneumoniae colonizing children in day-care centers in Lisbon: the Portuguese day-care center initiative

scientific article published in August 1999

Changes in pneumococcal serotypes and antibiotypes carried by vaccinated and unvaccinated day-care centre attendees in Portugal, a country with widespread use of the seven-valent pneumococcal conjugate vaccine.

scientific article published on 23 April 2009

Characteristics of Haemophilus influenzae invasive isolates from Portugal following routine childhood vaccination against H. influenzae serotype b (2002-2010).

scientific article published on 24 October 2013

Clonal evolution leading to maintenance of antibiotic resistance rates among colonizing Pneumococci in the PCV7 era in Portugal

scientific article

Comparative analysis of Streptococcus pneumoniae transmission in Portuguese and Finnish day-care centres

scientific article

Decrease in pneumococcal co-colonization following vaccination with the seven-valent pneumococcal conjugate vaccine

scientific article (publication date: 2012)

Denmark14-230 clone as an increasing cause of pneumococcal infection in Portugal within a background of diverse serotype 19A lineages.

scientific article

Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone.

scientific article

Disease isolates of Streptococcus pseudopneumoniae and non-typeable S. pneumoniae presumptively identified as atypical S. pneumoniae in Spain

scientific article

Diversity of penicillin-nonsusceptible Streptococcus pneumoniae circulating in Iceland after the introduction of penicillin-resistant clone Spain(6B)-2.

scientific article published on 9 September 2002

Dynamics of pneumococcal carriage in adults: a new look at an old paradigm

scientific article published on 02 September 2020

Emergence of a serotype 1 Streptococcus pneumoniae lineage colonising healthy children in Portugal in the seven-valent conjugate vaccination era.

scientific article published on 6 November 2007

Epidemiology and population structure of serotypes 1, 5 and 7f carried by children in Portugal from 1996-2010 before introduction of the 10-valent and 13-valent pneumococcal conjugate vaccines

scientific article

Evidence for soft selective sweeps in the evolution of pneumococcal multidrug resistance and vaccine escape

scientific article

Genomic Characterization of the Emerging Pathogen Streptococcus pseudopneumoniae

scientific article published on 25 June 2019

Global phylogenomic analysis of nonencapsulated Streptococcus pneumoniae reveals a deep-branching classic lineage that is distinct from multiple sporadic lineages

scientific article published on 04 December 2014

High invasiveness of pneumococcal serotypes included in the new generation of conjugate vaccines

scientific article published on 8 November 2013

High rates of transmission of and colonization by Streptococcus pneumoniae and Haemophilus influenzae within a day care center revealed in a longitudinal study

scientific article

Highly penicillin-resistant multidrug-resistant pneumococcus-like strains colonizing children in Oeiras, Portugal: genomic characteristics and implications for surveillance

scientific article

How direct competition shapes coexistence and vaccine effects in multi-strain pathogen systems.

scientific article published on 12 October 2015

Identification of Streptococcus pneumoniae by a real-time PCR assay targeting SP2020

Identification, prevalence and population structure of non-typable Streptococcus pneumoniae in carriage samples isolated from preschoolers attending day-care centres.

scientific article published in February 2006

Impact of a single dose of the 7-valent pneumococcal conjugate vaccine on colonization

scientific article published on 01 March 2010

Impact of private use of the 13-valent pneumococcal conjugate vaccine (PCV13) on pneumococcal carriage among Portuguese children living in urban and rural regions

scientific article published in 2021

Impact of the 13-valent pneumococcal conjugate vaccine on Streptococcus pneumoniae multiple serotype carriage

scientific article published on 17 June 2016

Large screening of CA-MRSA among Staphylococcus aureus colonizing healthy young children living in two areas (urban and rural) of Portugal

scientific article

Low prevalence of pneumococcal carriage and high serotype and genotype diversity among adults over 60 years of age living in Portugal

scientific article

Molecular Typing of Methicillin-Resistant Staphylococcus aureus by Pulsed-Field Gel Electrophoresis: Comparison of Results Obtained in a Multilaboratory Effort Using Identical Protocols and MRSA Strains

scientific article published on 01 January 2000

Multilocus Sequence Typing of Streptococcus pneumoniae Clones with Unusual Drug Resistance Patterns: Genetic Backgrounds and Relatedness to Other Epidemic Clones

scientific article published on 19 September 2001

Multiple-locus variable number tandem repeat analysis for Streptococcus pneumoniae: comparison with PFGE and MLST.

scientific article

Non-typeable pneumococci circulating in Portugal are of cps type NCC2 and have genomic features typical of encapsulated isolates

scientific article

Optochin resistance among Streptococcus pneumoniae strains colonizing healthy children in Portugal

scientific article published on 21 November 2007

Periodic cycles of pneumococcal serotypes carried by children before and after 7-valent pneumococcal conjugate vaccine

scientific article

Pherotypes of Co-Colonizing Pneumococci Among Portuguese Children

article

Pilot study of the genetic diversity of the pneumococcal nasopharyngeal flora among children attending day care centers

scientific article

Prevalence, risk factors, and epidemiology of methicillin-resistant Staphylococcus aureus carried by adults over 60 years of age.

scientific article published on 31 October 2014

Properties of novel international drug-resistant pneumococcal clones identified in day-care centers of Lisbon, Portugal.

scientific article

Puzzling Over the Pneumococcal Pangenome

scientific article published on 30 October 2018

Rapid identification of noncapsulated Streptococcus pneumoniae in nasopharyngeal samples allowing detection of co-colonization and reevaluation of prevalence ⬇️

scientific article published on September 9, 2011

Re-evaluation of Streptococcus pneumoniae carriage in Portuguese elderly by qPCR increases carriage estimates and unveils an expanded pool of serotypes

scientific article published on 20 May 2020

Selection of distinctive colony morphologies for detection of multiple carriage of Streptococcus pneumoniae

scientific article published in June 2013

Serotype Distribution, Antibiotic Resistance and Clonality of Streptococcus pneumoniae Isolated from Immunocompromised Patients in Tunisia.

scientific article

Serotypes and Clonal Diversity of Streptococcus pneumoniae Causing Invasive Disease in the Era of PCV13 in Catalonia, Spain

scientific article

Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group

scientific article published on December 2013

Streptococcus pneumoniae nasopharyngeal carriage in children attending day-care centers in the central region of Portugal, in the era of 7-valent pneumococcal conjugate vaccine

scientific article published on December 2009

Temporal trends and molecular epidemiology of recently described serotype 6C of Streptococcus pneumoniae

scientific article published on 10 December 2008

The blp Locus of Streptococcus pneumoniae Plays a Limited Role in the Selection of Strains That Can Cocolonize the Human Nasopharynx

scientific article published on 17 June 2016

The impact of private use of PCV7 in 2009 and 2010 on serotypes and antimicrobial resistance of Streptococcus pneumoniae carried by young children in Portugal: Comparison with data obtained since 1996 generating a 15-year study prior to PCV13 introd

scientific article

Upper Respiratory Tract Colonization With Streptococcus pneumoniae in Adults

scientific article published on 1 April 2020

Upper airways colonisation of Streptococcus pneumoniae in adults aged 60 years and older: a systematic review of prevalence and individual participant data meta-analysis of risk factors

scientific article published on 17 June 2020

Variable recombination dynamics during the emergence, transmission and 'disarming' of a multidrug-resistant pneumococcal clone

scientific article published on 23 June 2014

Virulence potential and genome-wide characterization of drug resistant Streptococcus pneumoniae clones selected in vivo by the 7-valent pneumococcal conjugate vaccine

scientific article

lytA-based identification methods can misidentify Streptococcus pneumoniae

scientific article published on 29 March 2016

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