List of works - Matthias Lochner

Active suppression of intestinal CD4(+)TCRαβ(+) T-lymphocyte maturation during the postnatal period

scientific article published on 21 July 2015

Anti-interleukin-18 therapy in murine models of inflammatory bowel disease

scientific article

Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control

scientific article published in November 2004

Critical role of ROR-γt in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation.

scholarly article

Critical role of the calpain/calpastatin balance in acute allograft rejection

scientific article published on 23 December 2010

DC activated via dectin-1 convert Treg into IL-17 producers

scientific article published on December 2008

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

scientific article published on 5 October 2014

Decreased susceptibility of mice to infection with Listeria monocytogenes in the absence of interleukin-18.

scientific article published on 23 June 2008

Development and Function of Secondary and Tertiary Lymphoid Organs in the Small Intestine and the Colon

scientific article

Development of a unique epigenetic signature during in vivo Th17 differentiation

scientific article

Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease

scientific article published on 24 June 2016

Dynamics of gut mucosal and systemic Th1/Th2 cytokine responses in interferon-gamma and interleukin-12p40 knock out mice during primary and challenge Cryptosporidium parvum infection

article

Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile

scientific article published on 10 March 2019

Erratum: De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

scientific article published on 01 April 2015

Fatty acid metabolism in the regulation of T cell function

scientific article

Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation

scientific article published on 26 August 2015

Generation of neutralizing mouse anti-mouse IL-18 antibodies for inhibition of inflammatory responses in vivo

article

IL-18 inhibits growth of murine orthotopic prostate carcinomas via both adaptive and innate immune mechanisms

scientific article

In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells

scientific article published on 26 May 2008

Inflammation recapitulates the ontogeny of lymphoid stromal cells

scientific article published in May 2009

Intestinal microbiota, evolution of the immune system and the bad reputation of pro-inflammatory immunity

scientific article published on 21 February 2011

IκBNS regulates murine Th17 differentiation during gut inflammation and infection

scientific article published on 18 February 2015

Lineage Relationship Analysis of RORγt+Innate Lymphoid Cells

scientific article published in Science

Metabolic pathways in T cell activation and lineage differentiation

scientific article

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

scientific article

Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells

scientific article

MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium.

scientific article

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

scientific article published on 20 February 2011

Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium

scientific article published on 19 March 2014

Restricted microbiota and absence of cognate TCR antigen leads to an unbalanced generation of Th17 cells

scientific article published on 22 December 2010

Stromal cells as trend-setters for cells migrating into the lymph node

scientific article published on 5 November 2014

Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection

scientific article published on 30 April 2020

The development of intestinal lymphoid tissues at the interface of self and microbiota

scientific article published on 09 September 2009

List of works by Matthias Lochner

Active suppression of intestinal CD4(+)TCRαβ(+) T-lymphocyte maturation during the postnatal period

Anti-interleukin-18 therapy in murine models of inflammatory bowel disease

Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control

Critical role of ROR-γt in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation.

Critical role of the calpain/calpastatin balance in acute allograft rejection

DC activated via dectin-1 convert Treg into IL-17 producers

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

Decreased susceptibility of mice to infection with Listeria monocytogenes in the absence of interleukin-18.

Development and Function of Secondary and Tertiary Lymphoid Organs in the Small Intestine and the Colon

Development of a unique epigenetic signature during in vivo Th17 differentiation

Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease

Dynamics of gut mucosal and systemic Th1/Th2 cytokine responses in interferon-gamma and interleukin-12p40 knock out mice during primary and challenge Cryptosporidium parvum infection

Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile

Erratum: De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

Fatty acid metabolism in the regulation of T cell function

Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation

Generation of neutralizing mouse anti-mouse IL-18 antibodies for inhibition of inflammatory responses in vivo

IL-18 inhibits growth of murine orthotopic prostate carcinomas via both adaptive and innate immune mechanisms

In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells

Inflammation recapitulates the ontogeny of lymphoid stromal cells

Intestinal microbiota, evolution of the immune system and the bad reputation of pro-inflammatory immunity

IκBNS regulates murine Th17 differentiation during gut inflammation and infection

Lineage Relationship Analysis of RORγt+Innate Lymphoid Cells

Metabolic pathways in T cell activation and lineage differentiation

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells

MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium.

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium

Restricted microbiota and absence of cognate TCR antigen leads to an unbalanced generation of Th17 cells

Stromal cells as trend-setters for cells migrating into the lymph node

Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection

The development of intestinal lymphoid tissues at the interface of self and microbiota