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List of works by Thomas Ve

A Sulfonozanamivir Analogue has Potent Anti-influenza Virus Activity.

scientific article published on 17 February 2018

A linker strategy for the production and crystallization of Toll/interleukin-1 receptor/resistance protein domain complexes

scientific article published on 15 March 2015

Adaptors in toll-like receptor signaling and their potential as therapeutic targets

scientific article published on October 2012

An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE

scientific article

Blood Group Antigen Recognition via the Group A Streptococcal M Protein Mediates Host Colonization

scientific article published on 24 January 2017

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB.

scientific article published on 28 September 2013

CorA Is a Copper Repressible Surface-Associated Copper(I)-Binding Protein Produced in Methylomicrobium album BG8

scientific article

Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

scientific article published on 26 April 2019

Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P.

scientific article published on 17 August 2017

Crystallization and X-ray diffraction analysis of the C-terminal domain of the flax rust effector protein AvrM.

scientific article published on 26 November 2011

Crystallization and X-ray diffraction analysis of the N-terminal domain of the Toll-like receptor signalling adaptor protein TRIF/TICAM-1.

scientific article published on 28 June 2013

Crystallization and preliminary X-ray diffraction analyses of the TIR domains of three TIR-NB-LRR proteins that are involved in disease resistance in Arabidopsis thaliana

scientific article published on 30 October 2013

Crystallization, X-ray diffraction analysis and preliminary structure determination of the TIR domain from the flax resistance protein L6.

scientific article

Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling

scientific article published on 01 September 2022

Death, TIR, and RHIM: Self-assembling domains involved in innate immunity and cell-death signaling

scientific article published on 05 December 2018

Fusion-protein-assisted protein crystallization

scientific article published on 27 June 2015

Intramolecular interaction influences binding of the Flax L5 and L6 resistance proteins to their AvrL567 ligands

scientific article

Mechanism of Bacterial Interference with TLR4 Signaling by Brucella Toll/Interleukin-1 Receptor Domain-containing Protein TcpB

scientific article

Megahertz serial crystallography

scientific article published in Nature Communications

Multiple functional self-association interfaces in plant TIR domains

scientific article

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

scientific article published on 10 May 2021

NAD+ cleavage activity by animal and plant TIR domains in cell death pathways

scientific article published on 01 August 2019

Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88

Protein crystal screening and characterization for serial femtosecond nanocrystallography

scientific article

Recombinant production of functional full-length and truncated human TRAM/TICAM-2 adaptor protein involved in Toll-like receptor and interferon signaling

scientific article published on 13 October 2014

Regulation of signaling by cooperative assembly formation in mammalian innate immunity signalosomes by molecular mimics.

scientific article

SARM1 is a metabolic sensor activated by an increased NMN/NAD<sup>+</sup> ratio to trigger axon degeneration

scientific article published on 02 March 2021

Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling.

scientific article published on 24 July 2017

Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation

scientific article

Structural basis for assembly and function of a heterodimeric plant immune receptor

scientific article

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling

scientific article

Structural characterization of macro domain–containing Thoeris antiphage defense systems

scientific article published in 2024

Structural insights into human parainfluenza virus type-3 haemagglutinin-neuraminidase using unsaturated 3- N-substituted sialic acids as probes.

scientific article

Structure and function of Toll/interleukin-1 receptor/resistance protein (TIR) domains

scientific article

Structures of the flax-rust effector AvrM reveal insights into the molecular basis of plant-cell entry and effector-triggered immunity

scientific article

Tetramerization is essential for the enzymatic function of the Pseudomonas aeruginosa virulence factor UDP-glucose pyrophosphorylase

scientific article published on 12 March 2024

The AvrM effector from flax rust has a structured C-terminal domain and interacts directly with the M resistance protein

scientific article

The Methylococcus capsulatus (Bath) secreted protein, MopE*, binds both reduced and oxidized copper

scientific article

The Single Nucleotide Polymorphism Mal-D96N Mice Provide New Insights into Functionality of Mal in TLR Immune Responses

scientific article published on 20 February 2019

The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.

scientific article

The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins

scientific article

The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathways

scientific article published on 26 February 2017

Towards the structure of the TIR-domain signalosome

scientific article published on 13 January 2017

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