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List of works by Pedro Dorado

ATA homozigosity in the IL-10gene promoter is a risk factor for schizophrenia in Spanish females: a case control study ⬇️

scientific article published on June 9, 2011

Allele and genotype frequencies of genes relevant to anti-epileptic drug therapy in Mexican-Mestizo healthy volunteers

scientific article published on 28 October 2016

Analysis of diclofenac and its metabolites by high-performance liquid chromatography: relevance of CYP2C9 genotypes in diclofenac urinary metabolic ratios.

scientific article published in June 2003

Antipsychotic drugs and QTc prolongation: the potential role of CYP2D6 genetic polymorphism.

scientific article published on February 2007

Aripiprazole-induced parkinsonism and its association with dopamine and serotonin receptor polymorphisms.

scientific article published in June 2008

Association between T102C and A-1438G polymorphisms in the serotonin receptor 2A (5-HT2A) gene and schizophrenia: relevance for treatment with antipsychotic drugs.

scientific article

Association of common genetic variants with risperidone adverse events in a Spanish schizophrenic population ⬇️

scientific article published on January 3, 2012

CYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards.

scientific article

CYP2C9 gene and susceptibility to major depressive disorder.

scientific article published in January 2003

CYP2C9 genotypes and diclofenac metabolism in Spanish healthy volunteers

scientific article published on 7 May 2003

CYP2C9, CYP2C19, ABCB1 genetic polymorphisms and phenytoin plasma concentrations in Mexican-Mestizo patients with epilepsy

scientific article published on 30 June 2015

CYP2D6 -1584C>G promoter polymorphism and debrisoquine ultrarapid hydroxylation in healthy volunteers

scientific article

CYP2D6 and the severity of suicide attempts

scientific article

CYP2D6 genetic polymorphisms in Southern Mexican Mayan Lacandones and Mestizos from Chiapas

scientific article published on January 2014

CYP2D6 genotype and debrisoquine hydroxylation phenotype in Cubans and Nicaraguans

scientific article published on 07 December 2010

CYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population

scientific article published on 15 November 2011

CYP2D6 polymorphism and mental and personality disorders in suicide attempters

scientific article published in December 2014

CYP2D6 polymorphism in patients with eating disorders

scientific article published on 28 September 2010

CYP2D6 polymorphism: implications for antipsychotic drug response, schizophrenia and personality traits

scientific article

CYP2D6 poor metabolizer status might be associated with better response to risperidone treatment

scientific article published in November 2013

CYP2D6 ultrarapid metabolism and early dropout from fluoxetine or amitriptyline monotherapy treatment in major depressive patients

scientific article published on 26 June 2012

Clinical implications of CYP2D6 genetic polymorphism during treatment with antipsychotic drugs.

scientific article published on December 2006

Determination of debrisoquine and 4-hydroxydebrisoquine by high-performance liquid chromatography: application to the evaluation of CYP2D6 genotype and debrisoquine metabolic ratio relationship

scientific article

Determination of fluoxetine and norfluoxetine in human plasma by high-performance liquid chromatography with ultraviolet detection in psychiatric patients.

scientific article

Determination of risperidone and 9-hydroxyrisperidone in human plasma by liquid chromatography: application to the evaluation of CYP2D6 drug interactions.

scientific article

Development of a HPLC method for the determination of losartan urinary metabolic ratio to be used for the determination of CYP2C9 hydroxylation phenotypes ⬇️

scientific article published on January 1, 2012

Development of a PCR-based strategy for CYP2D6 genotyping including gene multiplication of worldwide potential use.

scientific article

Development of a new genotyping assay for detection of the BDNF Val66Met polymorphism using melting-curve analysis

scientific article published in June 2009

Eating Disorder Symptoms and CYP2D6 Variation in Cuban Healthy Females: A Report from the Ibero-American Network of Pharmacogenetics

Effect of CYP2D6 and CYP2C9 genotypes on fluoxetine and norfluoxetine plasma concentrations during steady-state conditions.

scientific article

Effect of thioridazine dosage on the debrisoquine hydroxylation phenotype in psychiatric patients with different CYP2D6 genotypes.

scientific article published in December 2001

Estudio farmacogenético del polimorfismo metabólico de la debrisoquina (CYP2D6) en la población cubana en relación con la española

scientific article published on 01 May 2007

Evaluating a newly developed pharmacogenetic array: screening in a Spanish population.

scientific article published on November 2010

High frequency of CYP2D6 ultrarapid metabolizer genotypes in an Ashkenazi Jewish population from Argentina.

scientific article

High prevalence of CYP2D6 ultrarapid metabolizers in a mestizo Colombian population in relation to Hispanic mestizo populations

scientific article published on 30 October 2020

High risk of lifetime history of suicide attempts among CYP2D6 ultrarapid metabolizers with eating disorders

scientific article published on 15 February 2011

High-performance liquid chromatography method using ultraviolet detection for the quantification of aripiprazole and dehydroaripiprazole in psychiatric patients.

scientific article published in January 2012

Increased risk for major depression associated with the short allele of the serotonin transporter promoter region (5-HTTLPR-S) and the CYP2C9*3 allele

scientific article published on 01 August 2007

Influence of CYP2D6 deletion, multiplication, -1584C-->G, 31G-->A and 2988G-->a gene polymorphisms on dextromethorphan metabolism among Mexican tepehuanos and mestizos.

scientific article published on 30 June 2010

Influence of admixture components on CYP2C9*2 allele frequency in eight indigenous populations from Northwest Mexico.

scientific article

Interethnic differences in UGT1A4 genetic polymorphisms between Mexican Mestizo and Spanish populations.

scientific article

Interethnic differences in the relevance of CYP2C9 genotype and environmental factors for diclofenac metabolism in Hispanics from Cuba and Spain

scientific article

Interethnic relationships of CYP2D6 variants in native and Mestizo populations sharing the same ecosystem.

scientific article

Lessons from Cuba for Global Precision Medicine: CYP2D6 Genotype Is Not a Robust Predictor of CYP2D6 Ultrarapid Metabolism

scientific article

Liver enzyme abnormalities during antipsychotic treatment: a case report of risperidone-associated hepatotoxicity

scientific article published on 01 January 2014

Losartan hydroxylation phenotype in an Ecuadorian population: influence of CYP2C9 genetic polymorphism, habits and gender

Low frequency of CYP2D6 poor metabolizers among schizophrenia patients

article

Lower frequency of CYP2C9*2 in Mexican-Americans compared to Spaniards.

scientific article published in January 2004

MDR-1 genotypes and quetiapine pharmacokinetics in healthy volunteers.

scientific article published in January 2013

Neurological toxicity after phenytoin infusion in a pediatric patient with epilepsy: influence of CYP2C9, CYP2C19 and ABCB1 genetic polymorphisms

article

No effect of the CYP1A2*1F genotype on thioridazine, mesoridazine, sulforidazine plasma concentrations in psychiatric patients

scientific article published on 8 March 2007

Pharmacogenetics in Latin American populations: regulatory aspects, application to herbal medicine, cardiovascular and psychiatric disorders ⬇️

scientific article published on January 1, 2012

Pharmacogenetics of debrisoquine and its use as a marker for CYP2D6 hydroxylation capacity.

scientific article

Pharmacogenomics and Personality: Role of CYP2D6 and Implications for Psychopathology

article published in 2010

Pharmacokinetics of losartan and its metabolite E-3174 in relation to the CYP2C9 genotype

scientific article published in January 2002

QTc interval lengthening and debrisoquine metabolic ratio in psychiatric patients treated with oral haloperidol monotherapy.

scientific article published in June 2002

QTc interval lengthening is related to CYP2D6 hydroxylation capacity and plasma concentration of thioridazine in patients

scientific article

QTc interval, CYP2D6 and CYP2C9 genotypes and risperidone plasma concentrations.

scientific article

Reduced completed suicide rate in Hungary from 1990 to 2001: relation to suicide methods

scientific article published in October 2005

Relation between CYP2D6 genotype, personality, neurocognition and overall psychopathology in healthy volunteers

scientific article published in July 2009

Relation between CYP2D6 phenotype and genotype and personality in healthy volunteers

scientific article published in July 2008

Relationship between CYP2C8 genotypes and diclofenac 5-hydroxylation in healthy Spanish volunteers

scientific article published on 12 June 2008

Relationship between haloperidol plasma concentration, debrisoquine metabolic ratio, CYP2D6 and CYP2C9 genotypes in psychiatric patients.

scientific article published in March 2004

Relationship between risperidone and 9-hydroxy-risperidone plasma concentrations and CYP2D6 enzyme activity in psychiatric patients

scientific article

Relationship between the CYP2C9 IVS8-109A>T polymorphism and high losartan hydroxylation in healthy Ecuadorian volunteers

scientific article published on 01 August 2014

Relationships between CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 metabolic phenotypes and genotypes in a Nicaraguan Mestizo population

scientific article published on 06 October 2020

Relevance of CYP2D6 -1584C>G polymorphism for thioridazine:mesoridazine plasma concentration ratio in psychiatric patients.

scientific article published in July 2009

Reproducibility over time of the urinary diclofenac/4'-OH diclofenac ratio among different CYP2C9 genotypes

scientific article published in July 2003

Research Highlights

scientific article published on 01 April 2013

Research Highlights

Thioridazine steady-state plasma concentrations are influenced by tobacco smoking and CYP2D6, but not by the CYP2C9 genotype

scientific article published on 28 March 2003

Use of pharmacogenetics in bioequivalence studies to reduce sample size: an example with mirtazapine and CYP2D6.

scientific article published on 26 June 2012

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