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List of works by Marcello Pinti

Aging with HIV infection: a journey to the center of inflammAIDS, immunosenescence and neuroHIV.

scientific article published on July 2014

Altered clonogenic capability and stromal cell function characterize bone marrow of HIV-infected subjects with low CD4+ T cell counts despite viral suppression during HAART.

scientific article published in June 2008

Altered mitochondrial RNA production in adipocytes from HIV-infected individuals with lipodystrophy

scientific article published on 01 January 2005

Analysis of inflammasomes and antiviral sensing components reveals decreased expression of NLRX1 in HIV-positive patients assuming efficient antiretroviral therapy

scientific article

Anti-HIV drugs and the mitochondria

scientific article published on 11 May 2006

Apoptosis-resistant phenotype in HL-60-derived cells HCW-2 is related to changes in expression of stress-induced proteins that impact on redox status and mitochondrial metabolism.

scientific article published on February 2003

Apoptotic Features of Peripheral Blood Granulocytes and Monocytes during Primary, Acute HIV Infection

scientific article published in February 1999

Balanced regulation of mRNA production for Fas and Fas ligand in lymphocytes from centenarians: how the immune system starts its second century

scientific article published on 25 October 2004

CD4+ T-cell differentiation, regulatory T cells and gag-specific T lymphocytes are unaffected by CD4-guided treatment interruption and therapy resumption

scientific article published in July 2011

Changes in CD4+ cells’ miRNA expression following exposure to HIV-1.

scientific article published on 4 November 2010

Characterization of cells with different mitochondrial membrane potential during apoptosis

scientific article published in November 2005

Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for “inflamm-aging”

scientific article published on 13 February 2014

Cytometry, immunology, and HIV infection: three decades of strong interactions.

scientific article published on 20 June 2013

Cytotoxic granule release dominates gag-specific CD4+ T-cell response in different phases of HIV infection

scientific article published in April 2010

Decreased Circulating mtDNA Levels in Professional Male Volleyball Players

scientific article published on 10 June 2015

Decreased apoptosis of bone marrow progenitor cells in HIV-1-infected patients during highly active antiretroviral therapy

scientific article

Decreased mitochondrial DNA content in subcutaneous fat from HIV-infected women taking antiretroviral therapy as measured at delivery

scientific article published in January 2011

Deregulation of the CD95/CD95L system in lymphocytes from patients with primary acute HIV infection

scientific article published on March 2000

Development of real time PCR assays for the quantification of Fas and FasL mRNA levels in lymphocytes: studies on centenarians

scientific article

Different origin of adipogenic stem cells influences the response to antiretroviral drugs.

scientific article published on 31 July 2015

Different sensitivity to apoptosis in cells of monocytic or lymphocytic origin chronically infected with human immunodeficiency virus type-1.

scientific article published on December 2003

Differential course of HIV-1 infection and apolipoprotein E polymorphism

scientific article published in January 2007

Differential down-regulation of CD95 or CD95L in chronically HIV-infected cells of monocytic or lymphocytic origin: cellular studies and molecular analysis by quantitative competitive RT-PCR.

scientific article published on September 1999

Direct analysis of thymic function in children with Down's syndrome

scientific article

Drosophila Helical factor is an inducible protein acting as an immune-regulated cytokine in S2 cells

scientific article

Early changes in intramitochondrial cardiolipin distribution during apoptosis.

scientific article published in September 2002

Effect of treatment interruption monitored by CD4 cell count on mitochondrial DNA content in HIV-infected patients: a prospective study

scientific article published on October 2005

Effects of Energy Drink Acute Assumption in Gastrointestinal Tract of Rats

scientific article published in 2022

Effects of the change from Stavudine to tenofovir in human immunodeficiency virus-infected children treated with highly active antiretroviral therapy: studies on mitochondrial toxicity and thymic function

scientific article published in January 2008

Essential requirement of reduced glutathione (GSH) for the anti-oxidant effect of the flavonoid quercetin

scientific article published on November 2005

Features of 'CD4-exploders', HIV-positive patients with an optimal immune reconstitution after potent antiretroviral therapy

scientific article published in August 2002

Functional characterization of the promoter of the human Lon protease gene.

scientific article published on 7 October 2010

Genetic polymorphisms of Fas (CD95) and Fas ligand (CD178) influence the rise in CD4+ T cell count after antiretroviral therapy in drug-naïve HIV-positive patients

scientific article published on 13 September 2005

Genetic polymorphisms of Fas (CD95) and FasL (CD178) in human longevity: studies on centenarians

scientific article published on 28 March 2002

Genetic polymorphisms of Fas (CD95) and FasL (CD178) in human longevity: studies on centenarians

scientific article published on 01 April 2002

Guidelines for the use of flow cytometry and cell sorting in immunological studies

scientific article published on October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

scholarly article

HIV type 1 protease inhibitors enhance bone marrow progenitor cell activity in normal subjects and in HIV type 1-infected patients

scientific article published in January 2005

HIV-1 Infection and the Aging of the Immune System: Facts, Similarities and Perspectives

scientific article published in August 2011

HIV-DNA content in different CD4+ T-cell subsets correlates with CD4+ cell :  CD8+ cell ratio or length of efficient treatment.

scientific article

Hepatoma HepG2 cells as a model for in vitro studies on mitochondrial toxicity of antiviral drugs: which correlation with the patient?

scientific article published on April 2003

Herpes Simplex I virus impairs regenerative outcomes of periodontal regenerative therapy in intrabony defects: a pilot study

scientific article published in February 2012

Highly active antiretroviral therapy restores CD4+ Vbeta T-cell repertoire in patients with primary acute HIV infection but not in treatment-naive HIV+ patients with severe chronic infection

scientific article published in March 2004

Homeostatic cytokines and expansion of regulatory T cells accompany thymic impairment in children with Down syndrome

scientific article published in June 2008

Identification and characterization of an aspartyl protease from Cryptococcus neoformans

scientific article published on 16 July 2007

Identification of the Pseudomonas stutzeri OX1 toluene-o-xylene monooxygenase regulatory gene (touR) and of its cognate promoter.

scientific article

Immunological advantages of everolimus versus cyclosporin A in liver-transplanted recipients, as revealed by polychromatic flow cytometry.

scientific article

Immunophenotype of HIV+ patients during CD4 cell-monitored treatment interruption: role of the IL-7/IL-7 receptor system

scientific article published in October 2006

Impaired Mitochondrial Morphology and Functionality in Lonp1wt/- Mice

scientific article published on 08 June 2020

Impairment of recent thymic emigrants in HCV infection.

scientific article published in October 2005

Increased mitochondrial DNA content in peripheral blood lymphocytes from HIV-infected patients with lipodystrophy

scientific article published in August 2003

Increased plasma levels of extracellular mitochondrial DNA during HIV infection: A new role for mitochondrial damage-associated molecular patterns during inflammation

scientific article published in September 2011

Inhibition of Lon protease by triterpenoids alters mitochondria and is associated to cell death in human cancer cells

scientific article

Interfering with ROS Metabolism in Cancer Cells: The Potential Role of Quercetin.

scientific article published on 14 June 2010

LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells

scientific article published on 09 July 2018

MDR1 C3435T genetic polymorphism does not influence the response to antiretroviral therapy in drug-naive HIV-positive patients

scientific article published in July 2003

MMP-7 promoter polymorphisms do not influence CD4+ recovery and changes in plasma viral load during antiretroviral therapy for HIV-1 infection

scientific article published in October 2005

Markers of cell death-activation in lymphocytes of vertically HIV-infected children naive to highly active antiretroviral therapy: The role of age

scientific article published in September 2001

Mitochondria hyperfusion and elevated autophagic activity are key mechanisms for cellular bioenergetic preservation in centenarians.

scientific article

Mitochondrial DNA Haplogroups and Incidence of Lipodystrophy in HIV-Infected Patients on Long-Term Antiretroviral Therapy

article

Mitochondrial DNA haplogroups and highly active antiretroviral therapy-related lipodystrophy

scientific article published in October 2008

Mitochondrial DNA haplogroups and incidence of lipodystrophy in HIV-infected patients on long-term antiretroviral therapy

article

Mitochondrial DNA: a proinflammatory 'enemy from within' during HIV infection?

scientific article

Mitochondrial Lon protease at the crossroads of oxidative stress, ageing and cancer.

scientific article

Mitochondrial alterations and tendency to apoptosis in peripheral blood cells from children with Down syndrome

scientific article published on 17 January 2007

Mitochondrial changes during D-drug-containing once-daily therapy in HIV-positive treatment-naive patients.

scientific article published in January 2010

Mitochondrial functionality and metabolism in T cells from progressive multiple sclerosis patients

scientific article published on 16 August 2019

Mitochondrial functionality and mitochondrial DNA content in lymphocytes of vertically infected human immunodeficiency virus-positive children with highly active antiretroviral therapy-related lipodystrophy

scientific article published on 17 January 2002

Mitochondrial heterogeneity during staurosporine-induced apoptosis in HL60 cells: Analysis at the single cell and single organelle level

scientific article published in 2000

Mitochondrial liaisons of p53.

scientific article published on 07 January 2011

Mitochondrial neurogastrointestinal encephalomyopathy: evidence of mitochondrial DNA depletion in the small intestine

scientific article

Morphologic, histochemical, and functional analysis of platelet-rich plasma activity on skeletal cultured cells

scientific article published on August 2009

Multiparametric analysis of cells with different mitochondrial membrane potential during apoptosis by polychromatic flow cytometry

scientific article

Natural Compounds Modulating Mitochondrial Functions

scientific article

Novel genetic association of TNF-α-238 and PDCD1-7209 polymorphisms with long-term non-progressive HIV-1 infection.

scientific article published on 10 February 2013

OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion

scientific article published in February 2008

Opposite role of changes in mitochondrial membrane potential in different apoptotic processes

scientific article published on 8 March 2000

Persistent inflammation in HIV infection: established concepts, new perspectives

scientific article

Physiology and Immunology of the Thymus Gland

scientific article published in 2008

Placenta and cord blood mitochondrial DNA toxicity in HIV-infected women receiving nucleoside reverse transcriptase inhibitors during pregnancy

scientific article published in April 2003

Plasma HIV load and proviral DNA decreases after two standard antiretroviral regimens in HIV-positive patients naïve to antiretrovirals

scientific article published on January 2008

Polymorphisms of fas gene: relationship with Alzheimer's disease and cognitive decline.

scientific article published on 17 August 2006

Predictive Value of Intracellular HIV-1 DNA Levels During CD4-Guided Treatment Interruption in HIV+ Patients

article

Protective effect of acetyl-l-carnitine against oxidative stress induced by antiretroviral drugs

scientific article published on 14 November 2006

Quality assessment of human mitochondrial DNA quantification: MITONAUTS, an international multicentre survey

scientific article

Quercetin and cancer chemoprevention

scientific article

Quercetin inhibits lymphocyte activation and proliferation without inducing apoptosis in peripheral mononuclear cells

scientific article

Reliable and accurate CD4+ T cell count and percent by the portable flow cytometer CyFlow MiniPOC and "CD4 Easy Count Kit-Dry", as revealed by the comparison with the gold standard dual platform technology.

scientific article

Resistance of mtDNA-depleted cells to apoptosis

scientific article

Silencing of mitochondrial Lon protease deeply impairs mitochondrial proteome and function in colon cancer cells

scientific article published on 25 August 2014

Simultaneous analysis of reactive oxygen species and reduced glutathione content in living cells by polychromatic flow cytometry

scientific article

Sirtuin 3 interacts with Lon protease and regulates its acetylation status.

scientific article published on 13 August 2014

Small RNAs in prokaryotes and eukaryotes: a lesson for human immunologists: comment on "Diversity, evolution, and therapeutic applications of small RNAs in prokaryotic and eukaryotic immune systems" by Edwin L. Cooper and Nicola Overstreet

scientific article published on 2 December 2013

Stable changes in CD4+ T lymphocyte miRNA expression after exposure to HIV-1

article

Subject classification obtained by cluster analysis and principal component analysis applied to flow cytometric data.

scientific article

Successful treatment of HIV-1 infection increases the expression of a novel, short transcript for IL-18 receptor α chain.

scientific article published on November 2014

T cell activation but not polyfunctionality after primary HIV infection predicts control of viral load and length of the time without therapy.

scientific article

T cell homeostasis in centenarians: from the thymus to the periphery.

scientific article published on January 2010

Th1 and Th17 proinflammatory profile characterizes invariant natural killer T cells in virologically suppressed HIV+ patients with low CD4+/CD8+ ratio.

scientific article

The Role of Mitochondria in HIV Infection and Its Treatment

scientific article published in August 2010

The human immunodeficiency virus (HIV) protease inhibitor indinavir directly affects the opportunistic fungal pathogen Cryptococcus neoformans.

scientific article published on October 2004

The protease inhibitor atazanavir triggers autophagy and mitophagy in human preadipocytes.

scientific article published on October 2012

Thymic output and functionality of the IL-7/IL-7 receptor system in centenarians: implications for the neolymphogenesis at the limit of human life

scientific article published in April 2006

Upregulation of nuclear-encoded mitochondrial LON protease in HAART-treated HIV-positive patients with lipodystrophy: implications for the pathogenesis of the disease

scientific article

Viral strategies for the evasion of immunogenic cell death

scientific article published on May 2010

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