List of works - Alvaro R. Lara

Advances in host and vector development for the production of plasmid DNA vaccines

scientific article published on January 2014

Advances in the Development of Biotherapeutics.

scientific article published on 20 May 2015

Aerobic expression of Vitreoscilla hemoglobin efficiently reduces overflow metabolism in Escherichia coli

scientific article published on 18 March 2014

Design of a microaerobically inducible replicon for high-yield plasmid DNA production

scientific article published on 10 July 2019

Design of a synthetic miniR1 plasmid and its production by engineered Escherichia coli

scientific article published on 20 April 2019

Effect of growth rate on plasmid DNA production and metabolic performance of engineered Escherichia coli strains

scientific article published on 5 September 2013

Effect of the oxygen transfer rate on oxygen-limited production of plasmid DNA by Escherichia coli

scientific article published in 2019

Engineering E. coli for improved microaerobic pDNA production

scientific article published on 11 May 2019

Engineering Escherichia coli to improve culture performance and reduce formation of by-products during recombinant protein production under transient intermittent anaerobic conditions

scientific article published in August 2006

Engineering Escherichia coli to increase plasmid DNA production in high cell-density cultivations in batch mode

scientific article published on 19 September 2012

Enhanced plasmid DNA production by enzyme-controlled glucose release and an engineered Escherichia coli

scientific article published on 22 December 2015

Enhanced production of plasmid DNA by engineered Escherichia coli strains.

scientific article

Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategies

scientific article published on 21 June 2013

Evaluation of microbial globin promoters for oxygen-limited processes using Escherichia coli.

scientific article published on 13 November 2017

Fast dynamic response of the fermentative metabolism of Escherichia coli to aerobic and anaerobic glucose pulses

scientific article published in December 2009

Heterogeneous oxygen availability affects the titer and topology but not the fidelity of plasmid DNA produced by Escherichia coli

scientific article published on 4 July 2017

High Kanamycin Concentration as Another Stress Factor Additional to Temperature to Increase pDNA Production in E. coli DH5α Batch and Fed-Batch Cultures

scientific article published on 17 December 2019

High cell-density processes in batch mode of a genetically engineered Escherichia coli strain with minimized overflow metabolism using a pressurized bioreactor.

scientific article published on 12 July 2010

Inactivation of pyruvate kinase or the phosphoenolpyruvate: sugar phosphotransferase system increases shikimic and dehydroshikimic acid yields from glucose in Bacillus subtilis

scientific article published on 18 October 2013

Living with heterogeneities in bioreactors: understanding the effects of environmental gradients on cells

scientific article published on November 2006

Metabolic engineering of Escherichia coli for L-tyrosine production by expression of genes coding for the chorismate mutase domain of the native chorismate mutase-prephenate dehydratase and a cyclohexadienyl dehydrogenase from Zymomonas mobilis.

scientific article published on 14 March 2008

Metabolic variability in bioprocessing: implications of microbial phenotypic heterogeneity

Modification of glucose import capacity in Escherichia coli: physiologic consequences and utility for improving DNA vaccine production

scientific article published on 2 May 2013

Physiological effects of pH gradients on Escherichia coli during plasmid DNA production

scientific article published on 24 August 2015

Plasmid DNA Production in Proteome-Reduced Escherichia coli

scientific article published on 21 September 2020

Plasmid DNA production for therapeutic applications

scientific article published on January 2012

Replacement of the glucose phosphotransferase transport system by galactose permease reduces acetate accumulation and improves process performance of Escherichia coli for recombinant protein production without impairment of growth rate

scientific article published on 6 March 2006

Toward efficient microaerobic processes using engineeredEscherichia coliW3110 strains

Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale-down system

scientific article published in February 2006

Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: an alternative to fed-batch cultures

scientific article published in March 2008

Vitreoscilla Haemoglobin: A Tool to Reduce Overflow Metabolism

scientific article published in 2021

Vitreoscilla hemoglobin expression in engineered Escherichia coli: improved performance in high cell-density batch cultivations.

scientific article published on 11 July 2011

List of works by Alvaro R. Lara