Search filters

List of works by Athanasios Metaxas

Age-Dependent Changes in the Sarkosyl-Insoluble Proteome of APPSWE/PS1ΔE9 Transgenic Mice Implicate Dysfunctional Mitochondria in the Pathogenesis of Alzheimer’s Disease

scientific article published on 01 January 2018

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease

scientific article published on 31 October 2019

An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model

scientific article published on 28 April 2016

Binding characterization of N-(2-chloro-5-thiomethylphenyl)-N'-(3-[3 H]3 methoxy phenyl)-N'-methylguanidine ([3 H]GMOM), a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist

scientific article published on 01 February 2019

Bis-pyridylethenyl benzene as novel backbone for amyloid-β binding compounds

scientific article published on 18 May 2016

Cerebral level of vGlut1 is increased and level of glycine is decreased in TgSwDI mice

scientific article published in January 2014

Characterization of [3H] oxymorphone binding sites in mouse brain: Quantitative autoradiography in opioid receptor knockout mice.

scientific article published on 9 February 2017

Differential region-specific regulation of α4β2* nAChRs by self-administered and non-contingent nicotine in C57BL/6J mice

scientific article published on 23 August 2010

Effect of aging and Alzheimer's disease-like pathology on brain monoamines in mice.

scientific article

Established amyloid-β pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine.

scientific article

First in human evaluation of [F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors

Genetic deletion of the adenosine A(2A) receptor prevents nicotine-induced upregulation of α7, but not α4β2* nicotinic acetylcholine receptor binding in the brain.

scientific article

In vivo detection of amyloid-β deposits using heavy chain antibody fragments in a transgenic mouse model for Alzheimer's disease

scientific article

Increased Inflammation and Unchanged Density of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Postmortem Frontal Cortex of Alzheimer's Disease Patients

scientific article published on 05 December 2019

Increased desensitization of dopamine D₂ receptor-mediated response in the ventral tegmental area in the absence of adenosine A(2A) receptors.

scientific article published on 7 June 2011

Mouse strain differences in locomotor, sensitisation and rewarding effect of heroin; association with alterations in MOP-r activation and dopamine transporter binding

scientific article published in February 2010

Neurofibrillary tangles in Alzheimer's disease: elucidation of the molecular mechanism by immunohistochemistry and tau protein phospho-proteomics

scientific article published on October 2016

Neuroinflammation and amyloid-beta 40 are associated with reduced serotonin transporter (SERT) activity in a transgenic model of familial Alzheimer's disease

scientific article published on 01 May 2019

Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands

scientific article

Preclinical evaluation of [(18)F]PK-209, a new PET ligand for imaging the ion-channel site of NMDA receptors

scientific article published on 30 September 2014

Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy

scientific article published on 06 August 2019

Quantification of the novel N-methyl-d-aspartate receptor ligand [11C]GMOM in man

scientific article published on 05 October 2015

Reduced Serotonin Transporter Levels and Inflammation in the Midbrain Raphe of 12 month old APPswe/PSEN1dE9 Mice

scientific article

Region-specific up-regulation of oxytocin receptor binding in the brain of mice following chronic nicotine administration.

scientific article published on 30 May 2015

Serotonin augmentation therapy by escitalopram has minimal effects on amyloid-β levels in early-stage Alzheimer's-like disease in mice.

scientific article published on 12 September 2017

Structure-activity relationships of N-substituted 4-(trifluoromethoxy)benzamidines with affinity for GluN2B-containing NMDA receptors

scientific article

Subchronic treatment with phencyclidine in adolescence leads to impaired exploratory behavior in adult rats without altering social interaction or N-methyl-D-aspartate receptor binding levels

scientific article

Synthesis and preclinical evaluation of carbon-11 labelled N-((5-(4-fluoro-2-[(11)C]methoxyphenyl)pyridin-3-yl)methyl)cyclopentanamine as a PET tracer for NR2B subunit-containing NMDA receptors

scientific article published on 10 May 2014

Synthesis, radiolabeling and evaluation of novel amine guanidine derivatives as potential positron emission tomography tracers for the ion channel of the N-methyl-d-aspartate receptor.

scientific article published on 19 April 2016

Synthesis, radiolabeling and preclinical evaluation of a [11C]GMOM derivative as PET radiotracer for the ion channel of the N-methyl-D-aspartate receptor.

scientific article published on 8 May 2017

Synthesis, structure activity relationship, radiolabeling and preclinical evaluation of high affinity ligands for the ion channel of the N-methyl-d-aspartate receptor as potential imaging probes for positron emission tomography

scientific article published on 24 December 2014

TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics

scientific article published on 21 July 2017

The stereotypy-inducing and OCD-like effects of chronic 'binge' cocaine are modulated by distinct subtypes of nicotinic acetylcholine receptors

scientific article published on September 2012

Paulina is supported by:

About Paulina

Help