List of works by Ylva Hellsten

10-20-30 training increases performance and lowers blood pressure and VEGF in runners

scientific article published in December 2014

AMP deaminase in skeletal muscle of healthy males quantitatively determined by new assay

scientific article published on 01 April 1994

ATP-induced vasodilation and purinergic receptors in the human leg: roles of nitric oxide, prostaglandins, and adenosine

scientific article

Absence of humoral mediated 5'AMP-activated protein kinase activation in human skeletal muscle and adipose tissue during exercise.

scientific article published on 25 October 2007

Activation of estrogen response elements is mediated both via estrogen and muscle contractions in rat skeletal muscle myotubes

scientific article published on 19 November 2008

Adaptations with Intermittent Exercise Training in Post- and Premenopausal Women.

scientific article published in January 2017

Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells

scientific journal article

Adenosine contributes to blood flow regulation in the exercising human leg by increasing prostaglandin and nitric oxide formation.

scientific article published on 11 May 2009

Adenosine formation in contracting primary rat skeletal muscle cells and endothelial cells in culture

article

Aerobic exercise training lowers platelet reactivity and improves platelet sensitivity to prostacyclin in pre- and postmenopausal women.

scientific article published on 12 October 2017

Alpha adrenergic receptor blockade increases capillarization and fractional O2 extraction and lowers blood flow in contracting human skeletal muscle.

scientific article published on 15 February 2017

Anaerobic energy expenditure and mechanical efficiency during exhaustive leg press exercise

scientific article

Angiogenic potential is reduced in skeletal muscle of aged women

scientific article published on 22 September 2020

Angiogenic response to passive movement and active exercise in individuals with peripheral arterial disease.

scientific article published on 24 October 2013

Antioxidant supplementation enhances the exercise-induced increase in mitochondrial uncoupling protein 3 and endothelial nitric oxide synthase mRNA content in human skeletal muscle

scientific article published on 12 March 2007

Assessment of resistance vessel function in human skeletal muscle: guidelines for experimental design, Doppler ultrasound, and pharmacology

scientific article published on 30 December 2019

Attenuated purinergic receptor function in patients with type 2 diabetes

scientific article

Bengt Saltin (1935-2014).

scientific article published in December 2014

Biomarkers of vascular function in premenopausal and recent postmenopausal women of similar age: effect of exercise training

scientific article published on 29 January 2014

Caffeine-induced Ca2+ release increases AMPK-dependent glucose uptake in rodent soleus muscle

article

Calcium signalling in the regulation of PGC-1alpha, PDK4 and HKII mRNA expression

scientific journal article

Capillary growth in human skeletal muscle: physiological factors and the balance between pro-angiogenic and angiostatic factors.

scientific article

Capillary growth, ultrastructure remodelling and exercise training in skeletal muscle of essential hypertensive patients.

scientific article

Capillary ultrastructure and mitochondrial volume density in skeletal muscle in relation to reduced exercise capacity of patients with intermittent claudication.

scientific article published on 23 March 2016

Cardiac perfusion and function after high-intensity exercise training in late premenopausal and recent postmenopausal women: an MRI study

scientific article published on 14 March 2019

Cardiovascular Adaptations to Exercise Training

scientific article

Changes in plasma concentration of hypoxanthine and uric acid in man with short-distance running at various intensities

scientific article published on 01 December 1990

Chronic hypoxia increases arterial blood pressure and reduces adenosine and ATP induced vasodilatation in skeletal muscle in healthy humans.

scientific article published on 30 June 2014

Comparison of exogenous adenosine and voluntary exercise on human skeletal muscle perfusion and perfusion heterogeneity

scientific article published on 25 November 2009

Contraction-induced secretion of VEGF from skeletal muscle cells is mediated by adenosine.

scientific article published on 11 June 2010

Copenhagen Consensus statement 2019: physical activity and ageing

scientific article published on 21 February 2019

Cytochrome P450 2C9 plays an important role in the regulation of exercise-induced skeletal muscle blood flow and oxygen uptake in humans

scientific article

Decreased resting levels of adenine nucleotides in human skeletal muscle after high-intensity training

scientific article published on 01 May 1993

Differential regulation of IL-6 and TNF-alpha via calcineurin in human skeletal muscle cells.

scientific article

Dissociation between lactate and proton exchange in muscle during intense exercise in man

scientific article published on 01 October 1997

Early Postmenopausal Phase Is Associated With Reduced Prostacyclin-Induced Vasodilation That Is Reversed by Exercise Training: The Copenhagen Women Study.

scientific article published on 22 August 2016

Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model

scientific article published on 08 November 2019

Effect of PDE5 inhibition on the modulation of sympathetic α-adrenergic vasoconstriction in contracting skeletal muscle of young and older recreationally active humans.

scientific article published on 2 October 2015

Effect of acute exercise and exercise training on VEGF splice variants in human skeletal muscle

scientific article

Effect of birth weight and 12 weeks of exercise training on exercise-induced AMPK signaling in human skeletal muscle.

scientific article published on 23 April 2013

Effect of endurance versus resistance training on local muscle and systemic inflammation and oxidative stress in COPD

scientific article published on 19 June 2018

Effect of endurance versus resistance training on quadriceps muscle dysfunction in COPD: a pilot study

scientific article published on 27 October 2016

Effect of extraluminal ATP application on vascular tone and blood flow in skeletal muscle: implications for exercise hyperemia.

scientific article published on 12 June 2013

Effect of fiber type and nutritional state on AICAR- and contraction-stimulated glucose transport in rat muscle

scientific article

Effect of high intensity training on capillarization and presence of angiogenic factors in human skeletal muscle

scientific article published on 12 March 2004

Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice; impact of PGC-1α.

scientific article

Effect of menopause and exercise training on plasma apolipoprotein M and sphingosine-1-phosphate

scientific article published on 15 November 2018

Effect of nitric oxide synthase inhibition on the exchange of glucose and fatty acids in human skeletal muscle

scientific article published on 18 June 2013

Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans

scientific article

Effect of sprint cycle training on activities of antioxidant enzymes in human skeletal muscle

scientific article published on 01 October 1996

Effects of Exercise Training on Regulation of Skeletal Muscle Glucose Metabolism in Elderly Men

scientific article published on 19 May 2015

Effects of aging and exercise training on leg hemodynamics and oxidative metabolism in the transition from rest to steady-state exercise: role of cGMP signaling

scientific article published on 18 April 2018

Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle.

scientific article published on 5 May 2005

Effects of exercise training and resveratrol on vascular health in aging

scientific article published on 13 April 2016

Effects of high-intensity training on cardiovascular risk factors in premenopausal and postmenopausal women.

scientific article published on 23 December 2016

Effects of menopause and high-intensity training on insulin sensitivity and muscle metabolism.

scientific article

Endothelial mechanotransduction proteins and vascular function are altered by dietary sucrose supplementation in healthy young male subjects

scientific article

Energy metabolism during repeated sets of leg press exercise leading to failure or not

scientific article

Erythropoietin receptor in human skeletal muscle and the effects of acute and long-term injections with recombinant human erythropoietin on the skeletal muscle.

scientific article

Exchange of purines in human liver and skeletal muscle with short-term exhaustive exercise

scientific article published on 01 January 1994

Exercise Training Alters the Balance Between Vasoactive Compounds in Skeletal Muscle of Individuals With Essential Hypertension

scientific article published on 06 September 2011

Exercise but not prostanoids enhance levels of vascular endothelial growth factor and other proliferative agents in human skeletal muscle interstitium

scientific article published on 16 May 2003

Exercise training improves blood flow to contracting skeletal muscle of older men via enhanced cGMP signaling

scientific article

Exercise training modulates functional sympatholysis and α-adrenergic vasoconstrictor responsiveness in hypertensive and normotensive individuals

Exercise training normalizes skeletal muscle vascular endothelial growth factor levels in patients with essential hypertension

scientific article published on 01 June 2010

Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men

scientific article published on 10 February 2014

Exercise-induced increase in interstitial bradykinin and adenosine concentrations in skeletal muscle and peritendinous tissue in humans

scientific article published in August 2002

Extensive profiling of histidine‐containing dipeptides reveals species‐ and tissue‐specific distribution and metabolism in mice, rats, and humans

scientific article published in 2023

Formation of hydrogen peroxide and nitric oxide in rat skeletal muscle cells during contractions

scientific article published in September 2003

Four weeks of speed endurance training reduces energy expenditure during exercise and maintains muscle oxidative capacity despite a reduction in training volume.

scientific article

High metabolic substrate load induces mitochondrial dysfunction in rat skeletal muscle microvascular endothelial cells

scientific article published on 01 July 2021

High-intensity interval, but not endurance, training induces muscle fiber type-specific subsarcolemmal lipid droplet size reduction in type 2 diabetic patients

scientific article published on 17 July 2018

Homage to August Krogh celebrating the 90th anniversary of his Nobel prize in Physiology or Medicine

scientific article

Hyperinsulinemia does not cause de novo capillary recruitment in rat skeletal muscle

scientific article published on 12 October 2019

IMP metabolism in human skeletal muscle after exhaustive exercise

scientific article published on 01 January 1995

Immunohistochemical localization of xanthine oxidase in human cardiac and skeletal muscle

scientific article published on 01 September 1993

Impact of β-adrenergic signaling in PGC-1α-mediated adaptations in mouse skeletal muscle.

scientific article published on 5 September 2017

Impaired formation of vasodilators in peripheral tissue in essential hypertension is normalized by exercise training: role of adenosine and prostacyclin

scientific article

Increased skeletal muscle capillarization enhances insulin sensitivity.

scientific article published on 28 October 2014

Indication of in vivo xanthine oxidase activity in human skeletal muscle during exercise

scientific article

Infusion of ATP increases leg oxygen delivery but not oxygen uptake in the initial phase of intense knee-extensor exercise in humans

scientific article published on 01 August 2014

Inhibition of nitric oxide and prostaglandins, but not endothelial-derived hyperpolarizing factors, reduces blood flow and aerobic energy turnover in the exercising human leg

scientific article published on 08 March 2007

Inhibition of nitric oxide synthesis by systemic N(G)-monomethyl-L-arginine administration in humans: effects on interstitial adenosine, prostacyclin and potassium concentrations in resting and contracting skeletal muscle.

scientific article published in July 2000

Insulin-induced membrane permeability to glucose in human muscles at rest and following exercise

scientific article published on 09 January 2020

Intense intermittent exercise provides weak stimulus for vascular endothelial growth factor secretion and capillary growth in skeletal muscle.

scientific article

Intense interval training enhances human skeletal muscle oxygen uptake in the initial phase of dynamic exercise at high but not at low intensities

scientific article published on 02 July 2004

Interstitial and plasma adenosine stimulate nitric oxide and prostacyclin formation in human skeletal muscle

scientific article published on November 2010

Leg blood flow and skeletal muscle microvascular perfusion responses to submaximal exercise in peripheral arterial disease

scientific article published in November 2018

Leg blood flow is impaired during small muscle mass exercise in patients with COPD.

scientific article

Leg oxygen uptake in the initial phase of intense exercise is slowed by a marked reduction in oxygen delivery

scientific article published on 29 May 2013

Leg vascular and skeletal muscle mitochondrial adaptations to aerobic high-intensity exercise training are enhanced in the early postmenopausal phase.

scientific article published on 23 February 2017

Lifelong Physical Activity Determines Vascular Function in Late Postmenopausal Women

scientific article published on 01 March 2020

Lifelong physical activity prevents an age-related reduction in arterial and skeletal muscle nitric oxide bioavailability in humans

scientific article

Limitations of skeletal muscle oxygen supply in ageing

scientific article published on 01 April 2016

Local release of ATP into the arterial inflow and venous drainage of human skeletal muscle: insight from ATP determination with the intravascular microdialysis technique

scientific article published on 07 February 2011

Localization and function of ATP-sensitive potassium channels in human skeletal muscle

scientific article published on 27 September 2002

Localization of Nitric Oxide Synthase in Human Skeletal Muscle

scientific article published on 01 October 1996

Low blood flow at onset of moderate-intensity exercise does not limit muscle oxygen uptake

scientific article published on 20 January 2010

Muscle fibre type changes with sprint training: effect of training pattern

scientific article published on 01 October 1993

Muscle interstitial ATP and norepinephrine concentrations in the human leg during exercise and ATP infusion

scientific article published in October 2009

Muscle-strain injury exudate favors acute tissue healing and prolonged connective tissue formation in humans

scientific article published on 18 June 2019

Neuromuscular blockade of slow twitch muscle fibres elevates muscle oxygen uptake and energy turnover during submaximal exercise in humans

scientific article

Oestrogen, exercise and vascular function

scientific article published on 01 October 2019

Opposing effects of nitric oxide and prostaglandin inhibition on muscle mitochondrial Vo(2) during exercise

scientific article

Optimizing hyaluronidase dose and plasmid DNA delivery greatly improves gene electrotransfer efficiency in rat skeletal muscle

scientific article published on 22 October 2015

Oxidation of urate in human skeletal muscle during exercise

scientific article published on 01 January 1997

PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle.

scientific article published on 11 December 2007

PGC-1alpha mediates exercise-induced skeletal muscle VEGF expression in mice.

scientific article published on 28 April 2009

Partial neuromuscular blockade in humans enhances muscle blood flow during exercise independently of muscle oxygen uptake and acetylcholine receptor blockade.

scientific article published on 4 February 2009

Passive leg movement enhances interstitial VEGF protein, endothelial cell proliferation, and eNOS mRNA content in human skeletal muscle

scientific article published on 19 December 2007

Physical activity opposes the age-related increase in skeletal muscle and plasma endothelin-1 levels and normalizes plasma endothelin-1 levels in individuals with essential hypertension

scientific article

Plasma accumulation of hypoxanthine, uric acid and creatine kinase following exhausting runs of differing durations in man

scientific article published on 01 January 1991

Platelet responses to pharmacological and physiological interventions in middle-aged men with different habitual physical activity levels.

scientific article published on 3 January 2018

Potentiation of cGMP signaling increases oxygen delivery and oxidative metabolism in contracting skeletal muscle of older but not young humans.

scientific article published in August 2015

Pro- and anti-angiogenic factors in human skeletal muscle in response to acute exercise and training.

scientific article

Probenecid Inhibits α-Adrenergic Receptor-Mediated Vasoconstriction in the Human Leg Vasculature.

scientific article published on 30 October 2017

Reduced skeletal-muscle perfusion and impaired ATP release during hypoxia and exercise in individuals with type 2 diabetes

scientific article published on 03 January 2019

Reduced volume but increased training intensity elevates muscle Na+-K+ pump α1-subunit and NHE1 expression as well as short-term work capacity in humans

scientific article published on 19 December 2007

Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle

scientific article

Regulation of VEGF and bFGF mRNA expression and other proliferative compounds in skeletal muscle cells

scientific article published on January 2004

Regulation of bone blood flow in humans: The role of nitric oxide, prostaglandins, and adenosine

scientific article published on 29 January 2018

Regulatory Mechanisms of Estrogen on Vascular Ageing.

scientific article published on 28 April 2019

Relationship between performance at different exercise intensities and skeletal muscle characteristics

scientific article published on 24 March 2011

Reply from Lasse Gliemann, Jakob Schmidt, Jesper Olesen, Rasmus Sjørup Biensø, Sebastian Louis Peronard, Simon Udsen Grandjean, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten

scientific article published in October 2013

Reply fromLasse Gliemann, Jesper Olesen, Rasmus Sjorup Bienso, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten

scientific article published on 01 February 2014

Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men.

scientific article published on 22 July 2013

Resveratrol modulates the angiogenic response to exercise training in skeletal muscles of aged men.

scientific article published on 15 August 2014

Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension: effect of high-intensity aerobic training

scientific article published on 23 January 2012

Roles of sedentary aging and lifelong physical activity in exchange of glutathione across exercising human skeletal muscle.

scientific article published on 22 May 2014

Seven-day remote ischaemic preconditioning improves endothelial function in patients with type 2 diabetes mellitus: a randomised pilot study

scientific article published on 01 December 2019

Short-Term Supplementation With Fermented Red Clover Extract Reduces Vascular Inflammation in Early Post-menopausal Women

scientific article published on 10 February 2022

Skeletal Muscle Signaling and the Heart Rate and Blood Pressure Response to Exercise

article

Skeletal muscle PGC-1α is required for maintaining an acute LPS-induced TNFα response

scientific article published on 27 February 2012

Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a pet study with nitric oxide and cyclooxygenase inhibition.

scientific article published on 21 January 2011

Subcellular localization and mechanism of secretion of vascular endothelial growth factor in human skeletal muscle

scientific article

The Endothelial Mechanotransduction Protein Platelet Endothelial Cell Adhesion Molecule-1 Is Influenced by Aging and Exercise Training in Human Skeletal Muscle

scientific article published on 18 December 2018

The effect of high-intensity training on purine metabolism in man

scientific article published on 01 December 1993

The effect of nitric oxide synthase inhibition with and without inhibition of prostaglandins on blood flow in different human skeletal muscles.

scientific article published on 21 April 2017

The effect of passive movement training on angiogenic factors and capillary growth in human skeletal muscle.

scientific article

The effect of purinergic P2 receptor blockade on skeletal muscle exercise hyperemia in miniature swine

scientific article published on 25 June 2014

The effect of two exercise modalities on skeletal muscle capillary ultrastructure in individuals with type 2 diabetes

scientific article published on 04 January 2019

The effect of tyramine infusion and exercise on blood flow, coagulation and clot microstructure in healthy individuals

scientific article published in October 2018

The exercise timing hypothesis: can exercise training compensate for the reduction in blood vessel function after menopause if timed right?

scientific article published on 30 June 2019

The hyperaemic response to passive leg movement is dependent on nitric oxide: a new tool to evaluate endothelial nitric oxide function

scientific article published on 25 June 2012

The impact of acute remote ischaemic preconditioning on cerebrovascular function

scientific article published on 13 January 2020

The legacy of the Copenhagen School: in the footsteps of Lindhard and Krogh.

scientific article published in August 2010

Two weeks of muscle immobilization impairs functional sympatholysis but increases exercise hyperemia and the vasodilatory responsiveness to infused ATP

scientific article published on 09 March 2012

Vasoactive enzymes and blood flow responses to passive and active exercise in peripheral arterial disease

article

What turns off the angiogenic switch in skeletal muscle?

scientific article published on July 2015

Xanthine dehydrogenase and purine metabolism in man. With special reference to exercise

scientific article published on 01 January 1994

Xanthine oxidase in human skeletal muscle following eccentric exercise: a role in inflammation

scientific article