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List of works by Carleen Cullinane

18F-FLT PET as a surrogate marker of drug efficacy during mTOR inhibition by everolimus in a preclinical cisplatin-resistant ovarian tumor model

scientific article published on 16 September 2010

A Bivalent Inhibitor of Prostate Specific Membrane Antigen Radiolabeled with Copper-64 with High Tumor Uptake and Retention

scientific article published on 05 September 2019

A desferrioxamine B squaramide ester for the incorporation of zirconium-89 into antibodies

scientific article published in September 2016

A dual radiologic contrast agent protocol for 18F-FDG and 18F-FLT PET/CT imaging of mice bearing abdominal tumors.

scientific article published in June 2011

A microwave-assisted stereoselective synthesis of polyandrocarpamines A and B

AKT signalling is required for ribosomal RNA synthesis and progression of Eμ-Myc B-cell lymphoma in vivo

scientific article published on 13 February 2013

APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma

scientific article published on 17 July 2015

Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF<sup>V600</sup> melanoma

scientific article published on 01 March 2022

Adriamycin-induced inhibition of mitochondrial-encoded polypeptides as a model system for the identification of hotspots for DNA-damaging agents

article

Amplicon-dependent CCNE1 expression is critical for clonogenic survival after cisplatin treatment and is correlated with 20q11 gain in ovarian cancer

scientific article

An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

scientific article published on 3 January 2012

An in vitro transcription assay for probing drug-DNA interactions at individual drug sites

scientific article published on 01 August 1998

An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development

scientific article published in November 2005

Applications of positron emission tomography in the development of molecular targeted cancer therapeutics

scientific article published on January 2003

Applying Advanced Imaging Techniques to a Murine Model of Orthotopic Osteosarcoma

scientific article published on 3 August 2015

Barminomycin forms GC-specific adducts and virtual interstrand crosslinks with DNA

scientific article published on April 1999

Bifunctional (64)Cu-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography

scientific article

Botryllamides K and L, new tyrosine derivatives from the Australian ascidian Aplidium altarium ⬇️

article

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

scientific article published on 26 May 2020

Co-targeting deoxyribonucleic acid-dependent protein kinase and poly(adenosine diphosphate-ribose) polymerase-1 promotes accelerated senescence of irradiated cancer cells

scientific article published on February 2014

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

scientific article

Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas

scientific article published on 12 February 2013

Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling

scientific article

Control of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151.

scientific article

DNA damage by nitrogen mustard in a gene containing multiple Sp1-binding sites

article

DNA interstrand cross-links induced by psoralen are not repaired in mammalian mitochondria

scientific article published on 01 April 1998

DNA sequence-specific adducts of adriamycin and mitomycin C

scientific article published on 01 March 1989

DNA targeted platinum complexes: synthesis, cytotoxicity and DNA interactions of cis-dichloroplatinum(II) complexes tethered to phenazine-1-carboxamides

scientific article published in July 2000

Detection of Apoptotic Cells Using Immunohistochemistry

scientific article published on 03 November 2014

Detection of Apoptotic Cells Using Propidium Iodide Staining

scientific article published on 03 November 2014

Diagnostic imaging agents for Alzheimer's disease: copper radiopharmaceuticals that target Aβ plaques

scientific article published on 16 October 2013

Differential (18)F-FDG and 3'-deoxy-3'-(18)F-fluorothymidine PET responses to pharmacologic inhibition of the c-MET receptor in preclinical tumor models

scientific article

Dipyridophenazine Complexes of Cobalt(III): DNA Photocleavage and Photobiology

scholarly article by Alison M. Funston et al published 2005 in Australian Journal of Chemistry

Docetaxel pharmacokinetics and its correlation with two in vivo probes for cytochrome P450 enzymes: the C14-erythromycin breath test and the antipyrine clearance test

Does Adriamycin Induce Interstrand Cross-Links in DNA?

scientific article published on 01 April 1994

Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution formulations in mouse and rat tumor models

scientific article published on 27 January 2012

EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptor

scientific article

Enhancing PET Signal at Target Tissue in Vivo: Dendritic and Multimeric Tris(hydroxypyridinone) Conjugates for Molecular Imaging of αvβ3 Integrin Expression with Gallium-68.

scientific article published on 14 December 2016

Fluorodeoxyglucose-based positron emission tomography imaging to monitor drug responses in hematological tumors

scientific article published on October 2014

Fluorodeoxyglucose-based positron emission tomography imaging to monitor drug responses in solid tumors

scientific article published on October 2014

Formaldehyde activation of mitoxantrone yields CpG and CpA specific DNA adducts

scientific article published on February 2000

Formation of DNA adducts by formaldehyde-activated mitoxantrone.

scientific article published on July 1999

Formation of adriamycin--DNA adducts in vitro.

scientific article published on June 1994

Gemcitabine potentiates cisplatin cytotoxicity and inhibits repair of cisplatin-DNA damage in ovarian cancer cell lines

scientific article published on April 2003

High-resolution transcription assay for probing drug-DNA interactions at individual drug sites

scientific article published on 01 January 2001

Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth

scientific article published on 26 March 2018

Imaging of molecular target modulation in oncology: challenges of early clinical trials

Imaging of tumor hypoxia with [124I]IAZA in comparison with [18F]FMISO and [18F]FAZA--first small animal PET results.

scientific article published on January 2007

Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation

scientific article

In vitro transcription analysis of DNA adducts induced by cyanomorpholinoadriamycin

scientific article published on 01 October 1992

In vitro transcription analysis of DNA alkylation by nitrogen mustard

scientific article published on 01 August 1991

In vivo activity of combined PI3K/mTOR and MEK inhibition in a Kras(G12D);Pten deletion mouse model of ovarian cancer

scientific article

Inclusion complexes of the antitumour metallocenes Cp(2)MCl(2) (M = Mo, Ti) with cucurbit[n]urils

scientific article

Induction of stable transcriptional blockage sites by Adriamycin: GpC specificity of apparent Adriamycin-DNA adducts and dependence on iron(III) ions

scientific article published on 01 June 1990

Inhibiting the system xC-/glutathione axis selectively targets cancers with mutant-p53 accumulation

scientific article published on 28 March 2017

Inhibition of DNA-dependent protein kinase induces accelerated senescence in irradiated human cancer cells

scientific article

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

scientific article

Inhibition of RNA Polymerase II Transcription in Human Cell Extracts by Cisplatin DNA Damage

article

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53

scientific journal article

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

scientific article

Interstrand cross-linking by adriamycin in nuclear and mitochondrial DNA of MCF-7 cells

scientific article

Intramuscular Transplantation Improves Engraftment Rates for Esophageal Patient-Derived Tumor Xenografts

scientific article published on 18 February 2015

LRP1B deletion in high-grade serous ovarian cancers is associated with acquired chemotherapy resistance to liposomal doxorubicin

scientific article

Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model

scientific article published on 23 February 2016

Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines

scientific article

Measuring apoptosis in mammals in vivo

scientific article published on 3 November 2014

Mitochondrial and nuclear DNA damage induced by sulphur mustard in keratinocytes

scientific article published on 01 December 2001

Modulation of intratumoral hypoxia by the epidermal growth factor receptor inhibitor gefitinib detected using small animal PET imaging

scientific article published in September 2005

Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities

scientific article published on 3 October 2013

Multi-nuclear platinum complexes encapsulated in cucurbit[n]uril as an approach to reduce toxicity in cancer treatment

scientific article

Multi-tracer small animal PET imaging of the tumour response to the novel pan-Erb-B inhibitor CI-1033.

scientific article published in February 2006

New Tris(hydroxypyridinone) Bifunctional Chelators Containing Isothiocyanate Groups Provide a Versatile Platform for Rapid One-Step Labeling and PET Imaging with (68)Ga(3.).

scientific article published on 18 August 2015

New insight into drug-DNA interactions at individual drug binding sites probed by RNA polymerase during active transcription of the DNA

scientific article published on 01 February 1990

Nuclear and mitochondrial distribution of organoamidoplatinum(II) lesions in cisplatin-sensitive and -resistant adenocarcinoma cells.

scientific article published in April 2001

PET imaging of tumours with a 64Cu labeled macrobicyclic cage amine ligand tethered to Tyr3-octreotate

scientific article published on 7 November 2013

Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance

scientific article

Peptide receptor chemoradionuclide therapy in small cell carcinoma: from bench to bedside

scientific article published on 16 August 2014

Preclinical FLT-PET and FDG-PET imaging of tumor response to the multi-targeted Aurora B kinase inhibitor, TAK-901.

scientific article

Preclinical evaluation of nilotinib efficacy in an imatinib-resistant KIT-driven tumor model

scientific article

Preparation and cell growth inhibitory activity of [PtR(2)L(2)] (R=polyfluorophenyl, L(2)=diene, cyclohexane-1,2-diamine (chxn) or cis-(dimethyl sulfoxide)(2)) and the X-ray crystal structure of [Pt(C(6)F(5))(2)(cis-chxn)].

scientific article

RNAi-mediated knock-down of arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition

scientific article

Rapid kit-based (68)Ga-labelling and PET imaging with THP-Tyr(3)-octreotate: a preliminary comparison with DOTA-Tyr(3)-octreotate

scientific article

Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis

scientific article published on 18 September 2020

Resistance to CDK2 inhibitors is associated with selection of polyploid cells in CCNE1-amplified ovarian cancer

scientific article published on 4 September 2013

Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis

scientific article

Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo.

scientific article published on 25 November 2013

Selective Targeting of Cyclin E1-Amplified High-Grade Serous Ovarian Cancer by Cyclin-Dependent Kinase 2 and AKT Inhibition.

scientific article published on 23 September 2016

Sequence Specificity of (Cyanomorpholino)adriamycin Adducts in Human Cells

scientific article published on 01 May 1994

Stage-dependent therapeutic efficacy in PI3K/mTOR-driven squamous cell carcinoma of the skin

scientific article published on 13 December 2017

Strand breakage by decay of DNA-bound 124I provides a basis for combined PET imaging and Auger endoradiotherapy

scientific article published on 23 February 2016

Structural and anticancer properties of hydrogen bonded diphenyl phosphate adducts of Pt(IV) complexes: the importance of pKa matching

scientific article

Studies of a Cobalt(III) Complex of the MMP Inhibitor Marimastat: A Potential Hypoxia-Activated Prodrug

scientific article published on 01 January 2007

Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitors

scientific article published on 3 September 2013

Synthesis and antiproliferative activity of a series of new platinum and palladium diphosphane complexes

scientific article published on 17 January 2018

Synthesis, cytotoxicity and cucurbituril binding of triamine linked dinuclear platinum complexes

scientific article

Synthesis, cytotoxicity, cell uptake and DNA interstrand cross-linking of 4,4'-dipyrazolylmethane-linked multinuclear platinum anti-cancer complexes.

scientific article

Systematic differences in electrochemical reduction of the structurally characterized anti-cancer platinum(IV) complexes [Pt{((p-HC6F4)NCH2)2}-(pyridine)2Cl2], [Pt{((p-HC6F4)NCH2)2}(pyridine)2(OH)2], and [Pt{((p-HC6F4)NCH2)2}(pyridine)2(OH)Cl].

scientific article published on 27 July 2012

Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes

scientific article

The DNA sequence specificity of cyanomorpholinoadriamycin

scientific article published on 01 November 1991

The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer

scientific article published on 11 November 2020

The epigenetic regulator I-BET151 induces BIM-dependent apoptosis and cell cycle arrest of human melanoma cells.

scientific article

Thermal stability of DNA adducts induced by cyanomorpholinoadriamycin in vitro.

scientific article published on April 1993

Toxicity of cucurbit[7]uril and cucurbit[8]uril: an exploratory in vitro and in vivo study

scientific article published on 17 February 2010

Transcriptional footprinting of drug-DNA interactions.

scientific article published on January 1997

UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas

scientific article published on 15 December 2015

Ubiquitous expression of the Pik3caH1047R mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly.

scientific article

Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy

scientific article published on 21 February 2012

[(18)F]FLT-PET imaging does not always "light up" proliferating tumor cells

scientific article published on 14 December 2011

β -[¹⁸F]Fluoro Azomycin Arabinoside (β -[¹⁸F]FAZA): Synthesis, Radiofluorination and Preliminary PET Imaging of Murine A431 Tumors

scientific article published on 13 March 2017

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