List of works - Andrew Almond

A new route to carbohydrate secondary and tertiary structure using Raman spectroscopy and Raman optical activity

scientific article published on August 2010

A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function

scientific article published on 08 January 2014

Assigning kinetic 3D-signatures to glycocodes

scientific article published on 14 March 2012

Chemical polyglycosylation and nanolitre detection enables single-molecule recapitulation of bacterial sugar export

scientific article

Comparative pharmacology and computational modelling yield insights into allosteric modulation of human alpha7 nicotinic acetylcholine receptors.

scientific article published on 21 June 2009

Comparison of Aqueous Molecular Dynamics with NMR Relaxation and Residual Dipolar Couplings Favors Internal Motion in a Mannose Oligosaccharide

article

Complete assignment of hyaluronan oligosaccharides up to hexasaccharides

scientific article published on 04 October 2006

Defined megadalton hyaluronan polymer standards

scientific article published on 23 June 2006

Dependence of pyranose ring puckering on anomeric configuration: methyl idopyranosides

scientific article

Determining the molecular basis for the pH-dependent interaction between the link module of human TSG-6 and hyaluronan.

scientific article published on 15 February 2007

Does microsecond sugar ring flexing encode 3D-shape and bioactivity in the heparanome?

scientific article

Dynamic exchange between stabilized conformations predicted for hyaluronan tetrasaccharides: comparison of molecular dynamics simulations with available NMR data.

scientific article

Dynamics of hyaluronan oligosaccharides revealed by 15N relaxation

scientific article published in February 2005

Enzymatic and chemical methods for the generation of pure hyaluronan oligosaccharides with both odd and even numbers of monosaccharide units.

scientific article published on 27 March 2006

Experimental evidence for all-or-none cooperative interactions between the G1-domain of versican and multivalent hyaluronan oligosaccharides.

scientific article published on 26 September 2005

Exploiting the carboxylate chemical shift to resolve degenerate resonances in spectra of 13C-labelled glycosaminoglycans

scientific article published in October 2005

Free energy landscapes of iduronic acid and related monosaccharides

scientific article published on September 2010

Hyaluronan

scientific article published on 01 July 2007

Hyaluronan: the absence of amide-carboxylate hydrogen bonds and the chain conformation in aqueous solution are incompatible with stable secondary and tertiary structure models

scientific article published on June 2006

Hyaluronan: the local solution conformation determined by NMR and computer modeling is close to a contracted left-handed 4-fold helix.

scientific article

Investigating the molecular basis for the virulence of Escherichia coli K5 by nuclear magnetic resonance analysis of the capsule polysaccharide.

scientific article

Is N-acetyl-D-glucosamine a rigid 4C1 chair?

scientific article

Less is more when simulating unsulfated glycosaminoglycan 3D-structure: comparison of GLYCAM06/TIP3P, PM3-CARB1/TIP3P, and SCC-DFTB-D/TIP3P predictions with experiment

scientific article published in December 2010

Microsecond kinetics in model single- and double-stranded amylose polymers

scientific article

Molecular dynamics simulations of the two disaccharides of hyaluronan in aqueous solution.

scientific article published in July 1997

NMR spectra of oligosaccharides at ultra-high field (900 MHz) have better resolution than expected due to favourable molecular tumbling

scientific article published on 19 June 2006

Oligosaccharides implicated in recognition are predicted to have relatively ordered structures.

scientific article

Pd(II)-mediated assembly of porphyrin channels in bilayer membranes

scientific article published on 21 December 2010

Physical interpretation of residual dipolar couplings in neutral aligned media

scientific article published in August 2002

Predicting the molecular shape of polysaccharides from dynamic interactions with water

scientific article published on 17 December 2002

Proteoglycans and their heterogeneous glycosaminoglycans at the atomic scale

scientific article published on 16 February 2015

Quantification of free ligand conformational preferences by NMR and their relationship to the bioactive conformation

scientific article

Shaping up for structural glycomics: a predictive protocol for oligosaccharide conformational analysis applied to N-linked glycans

scientific article published on 30 October 2013

Structural characterisation of two forms of procyclic acidic repetitive protein expressed by procyclic forms of Trypanosoma brucei.

scientific article published on June 1997

The conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway

scientific article

The importance of including local correlation times in the calculation of inter-proton distances from NMR measurements: ignoring local correlation times leads to significant errors in the conformational analysis of the Glcα1–2Glcα linkage by NMR

scientific article published in 2006

The structural plasticity of heparan sulfate NA-domains and hence their role in mediating multivalent interactions is confirmed by high-accuracy (15)N-NMR relaxation studies.

scientific article published on 13 December 2007

Towards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: insights into other members of the link module superfamily.

scientific article

Towards understanding the interaction between oligosaccharides and water molecules

scientific article

Use of 15N-NMR to resolve molecular details in isotopically-enriched carbohydrates: sequence-specific observations in hyaluronan oligomers up to decasaccharides.

scientific article

Using Molecular Dynamics Simulations To Provide New Insights into Protein Structure on the Nanosecond Timescale: Comparison with Experimental Data and Biological Inferences for the Hyaluronan-Binding Link Module of TSG-6.

scientific article

List of works by Andrew Almond

A new route to carbohydrate secondary and tertiary structure using Raman spectroscopy and Raman optical activity

A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function

Assigning kinetic 3D-signatures to glycocodes

Chemical polyglycosylation and nanolitre detection enables single-molecule recapitulation of bacterial sugar export

Comparative pharmacology and computational modelling yield insights into allosteric modulation of human alpha7 nicotinic acetylcholine receptors.

Comparison of Aqueous Molecular Dynamics with NMR Relaxation and Residual Dipolar Couplings Favors Internal Motion in a Mannose Oligosaccharide

Complete assignment of hyaluronan oligosaccharides up to hexasaccharides

Defined megadalton hyaluronan polymer standards

Dependence of pyranose ring puckering on anomeric configuration: methyl idopyranosides

Determining the molecular basis for the pH-dependent interaction between the link module of human TSG-6 and hyaluronan.

Does microsecond sugar ring flexing encode 3D-shape and bioactivity in the heparanome?

Dynamic exchange between stabilized conformations predicted for hyaluronan tetrasaccharides: comparison of molecular dynamics simulations with available NMR data.

Dynamics of hyaluronan oligosaccharides revealed by 15N relaxation

Enzymatic and chemical methods for the generation of pure hyaluronan oligosaccharides with both odd and even numbers of monosaccharide units.

Experimental evidence for all-or-none cooperative interactions between the G1-domain of versican and multivalent hyaluronan oligosaccharides.

Exploiting the carboxylate chemical shift to resolve degenerate resonances in spectra of 13C-labelled glycosaminoglycans

Free energy landscapes of iduronic acid and related monosaccharides

Hyaluronan

Hyaluronan: the absence of amide-carboxylate hydrogen bonds and the chain conformation in aqueous solution are incompatible with stable secondary and tertiary structure models

Hyaluronan: the local solution conformation determined by NMR and computer modeling is close to a contracted left-handed 4-fold helix.

Investigating the molecular basis for the virulence of Escherichia coli K5 by nuclear magnetic resonance analysis of the capsule polysaccharide.

Is N-acetyl-D-glucosamine a rigid 4C1 chair?

Less is more when simulating unsulfated glycosaminoglycan 3D-structure: comparison of GLYCAM06/TIP3P, PM3-CARB1/TIP3P, and SCC-DFTB-D/TIP3P predictions with experiment

Microsecond kinetics in model single- and double-stranded amylose polymers

Molecular dynamics simulations of the two disaccharides of hyaluronan in aqueous solution.

NMR spectra of oligosaccharides at ultra-high field (900 MHz) have better resolution than expected due to favourable molecular tumbling

Oligosaccharides implicated in recognition are predicted to have relatively ordered structures.

Pd(II)-mediated assembly of porphyrin channels in bilayer membranes

Physical interpretation of residual dipolar couplings in neutral aligned media

Predicting the molecular shape of polysaccharides from dynamic interactions with water

Proteoglycans and their heterogeneous glycosaminoglycans at the atomic scale

Quantification of free ligand conformational preferences by NMR and their relationship to the bioactive conformation

Shaping up for structural glycomics: a predictive protocol for oligosaccharide conformational analysis applied to N-linked glycans

Structural characterisation of two forms of procyclic acidic repetitive protein expressed by procyclic forms of Trypanosoma brucei.

The conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway

The importance of including local correlation times in the calculation of inter-proton distances from NMR measurements: ignoring local correlation times leads to significant errors in the conformational analysis of the Glcα1–2Glcα linkage by NMR

The structural plasticity of heparan sulfate NA-domains and hence their role in mediating multivalent interactions is confirmed by high-accuracy (15)N-NMR relaxation studies.

Towards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: insights into other members of the link module superfamily.

Towards understanding the interaction between oligosaccharides and water molecules

Use of 15N-NMR to resolve molecular details in isotopically-enriched carbohydrates: sequence-specific observations in hyaluronan oligomers up to decasaccharides.

Using Molecular Dynamics Simulations To Provide New Insights into Protein Structure on the Nanosecond Timescale: Comparison with Experimental Data and Biological Inferences for the Hyaluronan-Binding Link Module of TSG-6.