List of works - Nigel J. Saunders

A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma.

scientific article published on 13 April 2016

A role for BELLRINGER in cell wall development is supported by loss-of-function phenotypes.

scientific article

A study of the interaction between recombinant bactericidal permeability increasing protein (rBPI(23)) and gentamicin

scientific article published in July 1995

Adaptation by phase variation in pathogenic bacteria.

scientific article

An oncogenic role of eIF3e/INT6 in human breast cancer

scientific article published on 10 May 2010

Analysis of leukocyte membrane protein interactions using protein microarrays

scientific article

Bacterial virulence factors in neonatal sepsis: group B streptococcus

scientific article published on June 2004

CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

scientific article

Colouring Space - A Coloured Framework for Spatial Modelling in Systems Biology

article by David Gilbert et al published 2013 in Lecture Notes in Computer Science

Comparative overview of the genomic and genetic differences between the pathogenic Neisseria strains and species.

scientific article

Comparison of the RpoH-dependent regulon and general stress response in Neisseria gonorrhoeae.

scientific article published on July 2006

Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58

scientific article

Complete and variant forms of the 'gonococcal genetic island' in Neisseria meningitidis.

scientific article

Coordinated regulation of the Neisseria gonorrhoeae-truncated denitrification pathway by the nitric oxide-sensitive repressor, NsrR, and nitrite-insensitive NarQ-NarP.

scientific article published on 05 September 2006

Crystal structure of nitrogen regulatory protein IIANtr from Neisseria meningitidis.

scientific article

Crystallization and preliminary X-ray analysis of CrgA, a LysR-type transcriptional regulator from pathogenic Neisseria meningitidis MC58

scientific article published on 9 August 2008

Deep resequencing of serial sputum isolates of Mycobacterium tuberculosis during therapeutic failure due to poor compliance reveals stepwise mutation of key resistance genes on an otherwise stable genetic background.

scientific article published on 13 January 2011

Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression

scientific article

Differential expression of microRNAs in Marek's disease virus-transformed T-lymphoma cell lines

scientific article published on 18 March 2009

Divergence and transcriptional analysis of the division cell wall (dcw) gene cluster in Neisseria spp.

scientific article published on January 2003

ERF5 and ERF6 play redundant roles as positive regulators of JA/Et-mediated defense against Botrytis cinerea in Arabidopsis

scientific article

EXACT2: the semantics of biomedical protocols

scientific article

Ecf, an alternative sigma factor from Neisseria gonorrhoeae, controls expression of msrAB, which encodes methionine sulfoxide reductase.

scientific article published on May 2006

Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma

scientific article

GLK transcription factors coordinate expression of the photosynthetic apparatus in Arabidopsis

scientific article

Genetic islands of Streptococcus agalactiae strains NEM316 and 2603VR and their presence in other Group B streptococcal strains

scientific article

Genome analysis and strain comparison of correia repeats and correia repeat-enclosed elements in pathogenic Neisseria

scientific article

Genome sequence of Rhodobacter sphaeroides Strain WS8N.

scientific article published on 27 May 2011

High rates of phase variation in Campylobacter jejuni

scientific article published on 01 June 2000

Host iron binding proteins acting as niche indicators for Neisseria meningitidis

scientific article

Identification of bacterial pathogens and antimicrobial resistance directly from clinical urines by nanopore-based metagenomic sequencing.

scientific article published on 25 September 2016

Implications of sequencing bacterial genomes for pathogenesis and vaccine development

scientific article published in December 1998

Inter-species horizontal transfer resulting in core-genome and niche-adaptive variation within Helicobacter pylori

scientific article

MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation

scientific article

Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.

scientific article

MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential

scientific article

MicroRNA expression in lymphocyte development and malignancy

article

MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

scientific article

Microarray genomotyping of key experimental strains of Neisseria gonorrhoeae reveals gene complement diversity and five new neisserial genes associated with Minimal Mobile Elements

scientific article

Mutation rates: estimating phase variation rates when fitness differences are present and their impact on population structure

scientific article

Neisseria meningitidis Lacking the Major Porins PorA and PorB Is Viable and Modulates Apoptosis and the Oxidative Burst of Neutrophils.

scientific article

On the origin of the treponematoses: a phylogenetic approach

scientific article

Orexin receptors exert a neuroprotective effect in Alzheimer's disease (AD) via heterodimerization with GPR103

scientific article published on 30 July 2015

Phase variation mediated niche adaptation during prolonged experimental murine infection with Helicobacter pylori.

scientific article

Population-associated differences between the phase variable LPS biosynthetic genes of Helicobacter pylori

scientific article published on 18 September 2006

Primary cutaneous anaplastic large cell lymphoma shows a distinct miRNA expression profile and reveals differences from tumor-stage mycosis fungoides

scientific article published on 01 August 2012

Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58

article

Sequence-based analysis of pQBR103; a representative of a unique, transfer-proficient mega plasmid resident in the microbial community of sugar beet

scientific article published on 05 July 2007

Simple sequence repeats in the Helicobacter pylori genome

scientific article published on March 1998

Species status of Neisseria gonorrhoeae: evolutionary and epidemiological inferences from multilocus sequence typing.

scientific article

Strain-specific differences in Neisseria gonorrhoeae associated with the phase variable gene repertoire

scientific article

Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 A resolution.

scientific article published on 31 May 2006

Structure of the cold-shock domain protein fromNeisseria meningitidisreveals a strand-exchanged dimer

scientific article

Structure of the regulatory domain of the LysR family regulator NMB2055 (MetR-like protein) fromNeisseria meningitidis

scientific article

The Consequences of Replicating in the Wrong Orientation: Bacterial Chromosome Duplication without an Active Replication Origin

scientific article published on 3 November 2015

The alpha-subunit of the heterotrimeric G-protein affects jasmonate responses in Arabidopsis thaliana

scientific article published on 2 April 2009

The crystal structure of NGO0477 from Neisseria gonorrhoeae reveals a novel protein fold incorporating a helix-turn-helix motif

scientific article

The human myometrium differentially expresses mTOR signalling components before and during pregnancy: evidence for regulation by progesterone.

scientific article published on 26 March 2013

The length of a tetranucleotide repeat tract in Haemophilus influenzae determines the phase variation rate of a gene with homology to type III DNA methyltransferases.

scientific article published on January 2000

The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as 'virulence genes'.

scientific article

The repertoire of minimal mobile elements in the Neisseria species and evidence that these are involved in horizontal gene transfer in other bacteria

scientific article published on 5 October 2007

The small FNR regulon of Neisseria gonorrhoeae: comparison with the larger Escherichia coli FNR regulon and interaction with the NarQ-NarP regulon

scientific article

The spectrum of hepatitis C antibody positive disease in a teaching hospital

scientific article published in March 1995

The structure and transcriptional analysis of a global regulator from Neisseria meningitidis

scientific article

The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators

scientific article

The structure of NMB1585, a MarR-family regulator fromNeisseria meningitidis

scientific article

The structure of a reduced form of OxyR from Neisseria meningitidis

scientific article

The use of the pan-Neisseria microarray and experimental design for transcriptomics studies of Neisseria.

scientific article published in January 2012

To the Editors of Biometrics:

scientific article published on 01 December 2004

Tolerogenicity is not an absolute property of a dendritic cell.

scientific article published in June 2010

Transcriptomic analysis reveals calcium regulation of specific promoter motifs in Arabidopsis

scientific article published on 15 November 2011

Trough-only monitoring of serum vancomycin concentrations in neonates

scientific article published on 01 January 1998

Two-step assembly dynamics of the Bacillus subtilis divisome

scientific article

Why monitor peak vancomycin concentrations?

scientific article published in The Lancet

Working from the particular to the general--the development of comparative genomics--a meeting report from the 4th Annual Conference on Microbial Genomes

scientific article published in June 2000

miRNA expression profiling of mycosis fungoides

scientific article published on 24 February 2011

List of works by Nigel J. Saunders

A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma.

A role for BELLRINGER in cell wall development is supported by loss-of-function phenotypes.

A study of the interaction between recombinant bactericidal permeability increasing protein (rBPI(23)) and gentamicin

Adaptation by phase variation in pathogenic bacteria.

An oncogenic role of eIF3e/INT6 in human breast cancer

Analysis of leukocyte membrane protein interactions using protein microarrays

Bacterial virulence factors in neonatal sepsis: group B streptococcus

CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

Colouring Space - A Coloured Framework for Spatial Modelling in Systems Biology

Comparative overview of the genomic and genetic differences between the pathogenic Neisseria strains and species.

Comparison of the RpoH-dependent regulon and general stress response in Neisseria gonorrhoeae.

Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58

Complete and variant forms of the 'gonococcal genetic island' in Neisseria meningitidis.

Coordinated regulation of the Neisseria gonorrhoeae-truncated denitrification pathway by the nitric oxide-sensitive repressor, NsrR, and nitrite-insensitive NarQ-NarP.

Crystal structure of nitrogen regulatory protein IIANtr from Neisseria meningitidis.

Crystallization and preliminary X-ray analysis of CrgA, a LysR-type transcriptional regulator from pathogenic Neisseria meningitidis MC58

Deep resequencing of serial sputum isolates of Mycobacterium tuberculosis during therapeutic failure due to poor compliance reveals stepwise mutation of key resistance genes on an otherwise stable genetic background.

Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression

Differential expression of microRNAs in Marek's disease virus-transformed T-lymphoma cell lines

Divergence and transcriptional analysis of the division cell wall (dcw) gene cluster in Neisseria spp.

ERF5 and ERF6 play redundant roles as positive regulators of JA/Et-mediated defense against Botrytis cinerea in Arabidopsis

EXACT2: the semantics of biomedical protocols

Ecf, an alternative sigma factor from Neisseria gonorrhoeae, controls expression of msrAB, which encodes methionine sulfoxide reductase.

Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma

GLK transcription factors coordinate expression of the photosynthetic apparatus in Arabidopsis

Genetic islands of Streptococcus agalactiae strains NEM316 and 2603VR and their presence in other Group B streptococcal strains

Genome analysis and strain comparison of correia repeats and correia repeat-enclosed elements in pathogenic Neisseria

Genome sequence of Rhodobacter sphaeroides Strain WS8N.

High rates of phase variation in Campylobacter jejuni

Host iron binding proteins acting as niche indicators for Neisseria meningitidis

Identification of bacterial pathogens and antimicrobial resistance directly from clinical urines by nanopore-based metagenomic sequencing.

Implications of sequencing bacterial genomes for pathogenesis and vaccine development

Inter-species horizontal transfer resulting in core-genome and niche-adaptive variation within Helicobacter pylori

MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation

Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.

MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential

MicroRNA expression in lymphocyte development and malignancy

MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

Microarray genomotyping of key experimental strains of Neisseria gonorrhoeae reveals gene complement diversity and five new neisserial genes associated with Minimal Mobile Elements

Mutation rates: estimating phase variation rates when fitness differences are present and their impact on population structure

Neisseria meningitidis Lacking the Major Porins PorA and PorB Is Viable and Modulates Apoptosis and the Oxidative Burst of Neutrophils.

On the origin of the treponematoses: a phylogenetic approach

Orexin receptors exert a neuroprotective effect in Alzheimer's disease (AD) via heterodimerization with GPR103

Phase variation mediated niche adaptation during prolonged experimental murine infection with Helicobacter pylori.

Population-associated differences between the phase variable LPS biosynthetic genes of Helicobacter pylori

Primary cutaneous anaplastic large cell lymphoma shows a distinct miRNA expression profile and reveals differences from tumor-stage mycosis fungoides

Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58

Sequence-based analysis of pQBR103; a representative of a unique, transfer-proficient mega plasmid resident in the microbial community of sugar beet

Simple sequence repeats in the Helicobacter pylori genome

Species status of Neisseria gonorrhoeae: evolutionary and epidemiological inferences from multilocus sequence typing.

Strain-specific differences in Neisseria gonorrhoeae associated with the phase variable gene repertoire

Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 A resolution.

Structure of the cold-shock domain protein fromNeisseria meningitidisreveals a strand-exchanged dimer

Structure of the regulatory domain of the LysR family regulator NMB2055 (MetR-like protein) fromNeisseria meningitidis

The Consequences of Replicating in the Wrong Orientation: Bacterial Chromosome Duplication without an Active Replication Origin

The alpha-subunit of the heterotrimeric G-protein affects jasmonate responses in Arabidopsis thaliana

The crystal structure of NGO0477 from Neisseria gonorrhoeae reveals a novel protein fold incorporating a helix-turn-helix motif

The human myometrium differentially expresses mTOR signalling components before and during pregnancy: evidence for regulation by progesterone.

The length of a tetranucleotide repeat tract in Haemophilus influenzae determines the phase variation rate of a gene with homology to type III DNA methyltransferases.

The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as 'virulence genes'.

The repertoire of minimal mobile elements in the Neisseria species and evidence that these are involved in horizontal gene transfer in other bacteria

The small FNR regulon of Neisseria gonorrhoeae: comparison with the larger Escherichia coli FNR regulon and interaction with the NarQ-NarP regulon

The spectrum of hepatitis C antibody positive disease in a teaching hospital

The structure and transcriptional analysis of a global regulator from Neisseria meningitidis

The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators

The structure of NMB1585, a MarR-family regulator fromNeisseria meningitidis

The structure of a reduced form of OxyR from Neisseria meningitidis

The use of the pan-Neisseria microarray and experimental design for transcriptomics studies of Neisseria.

To the Editors of Biometrics:

Tolerogenicity is not an absolute property of a dendritic cell.

Transcriptomic analysis reveals calcium regulation of specific promoter motifs in Arabidopsis

Trough-only monitoring of serum vancomycin concentrations in neonates

Two-step assembly dynamics of the Bacillus subtilis divisome

Why monitor peak vancomycin concentrations?

Working from the particular to the general--the development of comparative genomics--a meeting report from the 4th Annual Conference on Microbial Genomes

miRNA expression profiling of mycosis fungoides