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List of works by Matthias P. Mayer

A Multimeric Membrane Protein Reveals 14-3-3 Isoform Specificity in Forward Transport in Yeast

scientific article published on 25 May 2006

A model for handling cell stress.

scientific article published on 29 November 2016

A new set of useful cloning and expression vectors derived from pBlueScript.

scientific article

A prion-like domain in Hsp42 drives chaperone-facilitated aggregation of misfolded proteins

scientific article

Aha, another regulator for hsp90 chaperones

scientific article published on 01 December 2002

Allosteric regulation of Hsp70 chaperones by a proline switch

scientific article published in February 2006

Allosteric regulation of Hsp70 chaperones involves a conserved interdomain linker

scientific article published on 19 October 2006

Alternative modes of client binding enable functional plasticity of Hsp70.

scientific article

Amide hydrogen exchange reveals conformational changes in hsp70 chaperones important for allosteric regulation.

scientific article

An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly.

scientific article

An intrinsic quality-control mechanism ensures unconventional secretion of fibroblast growth factor 2 in a folded conformation

scientific article published on 25 August 2009

Analysis of subsecond protein dynamics by amide hydrogen exchange and mass spectrometry using a quenched-flow setup

scientific article published on 2 February 2005

Analyzing protein dynamics using hydrogen exchange mass spectrometry.

scientific article published on 29 November 2013

Asna1/TRC40-mediated membrane insertion of tail-anchored proteins

scientific article published on 7 April 2010

Backbone circularization of Bacillus subtilis family 11 xylanase increases its thermostability and its resistance against aggregation.

scientific article

Bag-1M accelerates nucleotide release for human Hsc70 and Hsp70 and can act concentration-dependent as positive and negative cofactor.

scientific article published on 5 July 2001

Bclaf1 promotes angiogenesis by regulating HIF-1α transcription in hepatocellular carcinoma

scientific article published on 26 October 2018

Chaperone action at the single-molecule level.

scientific article

Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity

scientific article published on 6 February 2012

Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence

scientific article published on 06 October 2021

Cross-monomer substrate contacts reposition the Hsp90 N-terminal domain and prime the chaperone activity

scientific article published on 31 October 2011

Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation

scientific article

Differences in conformational dynamics within the Hsp90 chaperone family reveal mechanistic insights

scientific article published on 10 June 2014

Dimerization of the human E3 ligase CHIP via a coiled-coil domain is essential for its activity.

scientific article published on 10 November 2003

Disruption and mapping of IDI1, the gene for isopentenyl diphosphate isomerase in Saccharomyces cerevisiae

scientific article (publication date: September 1992)

Dynamic enzyme docking to the ribosome coordinates N-terminal processing with polypeptide folding.

scientific article published on 16 June 2013

Dynamics of the regulation of Hsp90 by the co-chaperone Sti1 ⬇️

scientific article published on February 21, 2012

Dynamics of trigger factor interaction with translating ribosomes

scientific article published on 28 November 2007

Feedback regulation of heat shock factor 1 (Hsf1) activity by Hsp70-mediated trimer unzipping and dissociation from DNA

scientific article published on 03 June 2020

From a ratchet mechanism to random fluctuations evolution of Hsp90's mechanochemical cycle

scientific article published on 06 August 2012

Function, evolution, and structure of J-domain proteins

scientific article published on 26 November 2018

Functional characterization of the atypical Hsp70 subunit of yeast ribosome-associated complex

scientific article published on 27 September 2007

Functional diversity between HSP70 paralogs due to variable interactions with specific co-chaperones

scientific article published on 13 April 2020

HIV-Tat Protein Forms Phosphoinositide-dependent Membrane Pores Implicated in Unconventional Protein Secretion

scientific article published on 16 July 2015

Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux

scientific article

Hsp110 is a nucleotide-activated exchange factor for Hsp70.

scientific article published on 24 January 2008

Hsp70 chaperone dynamics and molecular mechanism

scientific article published on 05 September 2013

Hsp70 chaperone machines.

scientific article

Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain

scientific article published on 18 October 2009

Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1.

scientific article published on 12 June 2019

Hsp90: breaking the symmetry.

scientific article published on April 2015

Human Hsp70 Disaggregase Reverses Parkinson's-Linked α-Synuclein Amyloid Fibrils

scientific article published on 19 August 2015

Human and yeast Hsp110 chaperones exhibit functional differences

scientific article published on 9 December 2005

Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling.

scientific article

Impaired interdomain communication in mitochondrial Hsp70 results in the loss of inward-directed translocation force

scientific article published on 26 November 2008

Influence of GrpE on DnaK-substrate interactions

scientific article published on 21 April 2004

Insights into the conformational dynamics of the E3 ubiquitin ligase CHIP in complex with chaperones and E2 enzymes

scientific article

Insights into the molecular mechanism of allostery in Hsp70s

scientific article

Intra-molecular pathways of allosteric control in Hsp70s

scientific article published on 01 June 2018

Investigation of the interaction between DnaK and DnaJ by surface plasmon resonance spectroscopy.

scientific article published in June 1999

Isoform-Specific Phosphorylation in Human Hsp90β Affects Interaction with Clients and the Cochaperone Cdc37.

scientific article published on 18 January 2017

Large Rotation of the N-terminal Domain of Hsp90 Is Important for Interaction with Some but Not All Client Proteins

scientific article published on 28 March 2017

Light-induced differences in conformational dynamics of the circadian clock regulator VIVID.

scientific article published on 2 November 2013

Lipids Trigger a Conformational Switch That Regulates Signal Recognition Particle (SRP)-mediated Protein Targeting

scientific article

Mapping temperature-induced conformational changes in the Escherichia coli heat shock transcription factor sigma 32 by amide hydrogen exchange.

scientific article

Mechanics of Hsp70 chaperones enables differential interaction with client proteins.

scientific article published on 30 January 2011

Mechanism of substrate recognition by Hsp70 chaperones.

scientific article published in August 2004

Modeling Hsp70-mediated protein folding

scientific article published on 28 April 2006

Modulation of substrate specificity of the DnaK chaperone by alteration of a hydrophobic arch

scientific article published on 01 December 2000

Molecular basis for regulation of the heat shock transcription factor sigma32 by the DnaK and DnaJ chaperones.

scientific article

Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1.

scientific article published on 19 January 2016

Molecular oxygen and the state of geometric isomerism of intermediates are essential in the carotene desaturation and cyclization reactions in daffodil chromoplasts

scientific article published on 01 September 1989

Multistep mechanism of substrate binding determines chaperone activity of Hsp70

scientific article published on 01 July 2000

Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction

scientific article published on 5 December 2016

Mutations in the DnaK chaperone affecting interaction with the DnaJ cochaperone.

scientific article

Nucleotide exchange factors Fes1 and HspBP1 mimic substrate to release misfolded proteins from Hsp70.

scientific article published in January 2018

Nucleotide exchange factors for Hsp70 chaperones

scientific article published on 01 January 2011

Pathways of allosteric regulation in Hsp70 chaperones.

scientific article

Phosphotyrosine confers client specificity to Hsp90.

scientific article

Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding

scientific article published in July 2017

Protein farnesyltransferase: production in Escherichia coli and immunoaffinity purification of the heterodimer from Saccharomyces cerevisiae.

scientific article

Pseudo-T-even bacteriophage RB49 encodes CocO, a cochaperonin for GroEL, which can substitute for Escherichia coli's GroES and bacteriophage T4's Gp31.

scientific article published on 4 December 2000

Quinone compounds are able to replace molecular oxygen as terminal electron acceptor in phytoene desaturation in chromoplasts of Narcissus pseudonarcissus L

scientific article published on 01 July 1990

Rapid desalting of protein samples for on-line microflow electrospray ionization mass spectrometry

scientific article published on 29 December 2004

Recent advances in the structural and mechanistic aspects of Hsp70 molecular chaperones

scientific article published on 19 November 2018

Recruitment of Hsp70 chaperones: a crucial part of viral survival strategies.

scientific article published in January 2005

Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2

scientific article published on 5 July 2016

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding.

scientific article

Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine

scientific article published on 22 January 2009

Structure and Dynamics of the ATP-Bound Open Conformation of Hsp70 Chaperones ⬇️

scientific article published on December 28, 2012

Structure-function analysis of HscC, the Escherichia coli member of a novel subfamily of specialized Hsp70 chaperones

scientific article

Targeting heat shock protein 90 with non-quinone inhibitors: a novel chemotherapeutic approach in human hepatocellular carcinoma.

scientific article published in July 2009

The Drosophila mitotic inhibitor Frühstart specifically binds to the hydrophobic patch of cyclins.

scientific article published on 13 April 2007

The Hsp40 J-domain modulates Hsp70 conformation and ATPase activity with a semi-elliptical spring

scientific article published on 7 July 2017

The Hsp70 chaperone network

scientific article published on 01 November 2019

The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway

scientific article published on 16 October 2017

The Unfolding Story of a Redox Chaperone ⬇️

scientific article published on 01 March 2012

The chaperone network connected to human ribosome-associated complex

scientific article

The novolactone natural product disrupts the allosteric regulation of Hsp70

scientific article

The oxidation state of the cytoplasmic glutathione redox system does not correlate with replicative lifespan in yeast

scientific article published on 15 December 2016

The universe of Hsp90.

scientific article

Timing the catch

scientific article

Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange.

scientific article published in May 2001

Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR

scientific article published on 24 December 2019

YfhJ, a Molecular Adaptor in Iron-Sulfur Cluster Formation or a Frataxin-like Protein?

scientific article published on 01 May 2006

c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells

scientific article published on 28 July 2015

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