List of works - Irina Artsimovitch

A Screen for rfaH Suppressors Reveals a Key Role for a Connector Region of Termination Factor Rho.

scientific article

A novel non-radioactive primase–pyrophosphatase activity assay and its application to the discovery of inhibitors of Mycobacterium tuberculosis primase DnaG ⬇️

scientific article published on December 24, 2012

Allosteric control of catalysis by the F loop of RNA polymerase

scientific article published on 23 October 2009

An insertion in the catalytic trigger loop gates the secondary channel of RNA polymerase

scientific article

An α Helix to β Barrel Domain Switch Transforms the Transcription Factor RfaH into a Translation Factor

scientific article

Ancient Transcription Factors in the News

scientific article published on 26 February 2019

Cloning, expression, purification, crystallization and initial crystallographic analysis of transcription elongation factors GreB from Escherichia coli and Gfh1 from Thermus thermophilus

scientific article

Crystallization and preliminary crystallographic analysis of the transcriptional regulator RfaH from Escherichia coli and its complex with ops DNA

scientific article

Discrimination against deoxyribonucleotide substrates by bacterial RNA polymerase

scientific article

DksA2, a zinc-independent structural analog of the transcription factor DksA

scientific article

E. coli RNA Polymerase Determinants of Open Complex Lifetime and Structure

scientific article published on 6 June 2015

Flipping states: a few key residues decide the winning conformation of the only universally conserved transcription factor

scientific article published on 10 June 2017

Fluorescence Resonance Energy Transfer Characterization of DNA Wrapping in Closed and Open Escherichia coli RNA Polymerase-λP(R) Promoter Complexes

scientific article published on 21 March 2016

Functional analysis of Thermus thermophilus transcription factor NusG

scientific article

Functional regions of the N-terminal domain of the antiterminator RfaH.

scientific article published on February 2010

Functional specialization of transcription elongation factors

scientific article published on 18 December 2008

Highly divergent RfaH orthologs from pathogenic proteobacteria can substitute for Escherichia coli RfaH both in vivo and in vitro

scientific article published on May 2004

In silico discovery of small molecules that inhibit RfaH recruitment to RNA polymerase

scientific article published on 2 October 2018

Initial events in bacterial transcription initiation ⬇️

scientific article

Interdomain Contacts Control Native State Switching of RfaH on a Dual-Funneled Landscape

scientific article

Interdomain contacts control folding of transcription factor RfaH.

scientific article

Interplay between the trigger loop and the F loop during RNA polymerase catalysis

scientific article published on October 2013

Interplay of DNA repair with transcription: from structures to mechanisms

scientific article published on 17 October 2012

Is it easy to stop RNA polymerase?

scientific article

Locking the nontemplate DNA to control transcription

scientific article published on 01 August 2018

Maintenance of Transcription-Translation Coupling by Elongation Factor P.

scientific article published on 13 September 2016

Mechanism of chromatin remodeling and recovery during passage of RNA polymerase II.

scientific article

Modulation of RNA polymerase activity through the trigger loop folding ⬇️

scientific article published on September 1, 2010

Multiple roles of the RNA polymerase {beta}' SW2 region in transcription initiation, promoter escape, and RNA elongation

scientific article

Nucleotide excision repair (NER) machinery recruitment by the transcription-repair coupling factor involves unmasking of a conserved intramolecular interface

scientific article

NusG-Spt5 Proteins—Universal Tools for Transcription Modification and Communication ⬇️

scientific article published on May 2, 2013

Origins and Molecular Evolution of the NusG Paralog RfaH

scientific article published on 27 October 2020

Post-initiation control by the initiation factor sigma

scientific article

Purification of bacterial RNA polymerase: tools and protocols

scientific article

RNA polymerase gate loop guides the nontemplate DNA strand in transcription complexes.

scientific article published on 12 December 2016

Rebuilding the bridge between transcription and translation

scientific article published on 27 April 2018

Regulation of Transcript Elongation

scientific article published on 24 June 2015

Regulation through the RNA polymerase secondary channel. Structural and functional variability of the coiled-coil transcription factors

scientific article

Response to Klyuyev and Vassylyev: on the mechanism of tagetitoxin inhibition of transcription

scientific article

Role of a Zn-independent DksA in Zn homeostasis and stringent response

scientific journal article

Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase ρ

scientific article

Structural Basis for Converting a General Transcription Factor into an Operon-Specific Virulence Regulator

scientific article

Structural basis for substrate loading in bacterial RNA polymerase

scientific article

Structural basis for transcription elongation by bacterial RNA polymerase

scientific article

Structural basis for transcription inhibition by tagetitoxin

scientific article

Tagetitoxin inhibits RNA polymerase through trapping of the trigger loop

scientific article

Termination and antitermination: RNA polymerase runs a stop sign ⬇️

scientific article published on April 11, 2011

The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation

scientific article published on 30 November 2012

The carboxy-terminal coiled-coil of the RNA polymerase β′-subunit is the main binding site for Gre factors

scientific article

The dormancy-specific regulator, SutA, is intrinsically disordered and modulates transcription initiation in Pseudomonas aeruginosa

scientific article published on 10 July 2019

The elongation factor RfaH and the initiation factor sigma bind to the same site on the transcription elongation complex

scholarly article

The β Subunit Gate Loop Is Required for RNA Polymerase Modification by RfaH and NusG ⬇️

scientific article published on July 22, 2011

The δ subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling

scientific article published on 18 December 2020

Transcription inactivation through local refolding of the RNA polymerase structure

scientific article

Transcription initiation factor DksA has diverse effects on RNA chain elongation ⬇️

scientific article published on December 30, 2011

Transcription termination control of the S box system: direct measurement of S-adenosylmethionine by the leader RNA.

scholarly article

Transcriptional pausing coordinates folding of the aptamer domain and the expression platform of a riboswitch ⬇️

scientific article published on February 13, 2012

Transformation: the next level of regulation

scientific article

Ubiquitous transcription factors display structural plasticity and diverse functions: NusG proteins - Shifting shapes and paradigms

scientific article

pH dependence of the stress regulator DksA

scientific article published on 23 March 2015

List of works by Irina Artsimovitch

A Screen for rfaH Suppressors Reveals a Key Role for a Connector Region of Termination Factor Rho.

A novel non-radioactive primase–pyrophosphatase activity assay and its application to the discovery of inhibitors of Mycobacterium tuberculosis primase DnaG ⬇️

Allosteric control of catalysis by the F loop of RNA polymerase

An insertion in the catalytic trigger loop gates the secondary channel of RNA polymerase

An α Helix to β Barrel Domain Switch Transforms the Transcription Factor RfaH into a Translation Factor

Ancient Transcription Factors in the News

Cloning, expression, purification, crystallization and initial crystallographic analysis of transcription elongation factors GreB from Escherichia coli and Gfh1 from Thermus thermophilus

Crystallization and preliminary crystallographic analysis of the transcriptional regulator RfaH from Escherichia coli and its complex with ops DNA

Discrimination against deoxyribonucleotide substrates by bacterial RNA polymerase

DksA2, a zinc-independent structural analog of the transcription factor DksA

E. coli RNA Polymerase Determinants of Open Complex Lifetime and Structure

Flipping states: a few key residues decide the winning conformation of the only universally conserved transcription factor

Fluorescence Resonance Energy Transfer Characterization of DNA Wrapping in Closed and Open Escherichia coli RNA Polymerase-λP(R) Promoter Complexes

Functional analysis of Thermus thermophilus transcription factor NusG

Functional regions of the N-terminal domain of the antiterminator RfaH.

Functional specialization of transcription elongation factors

Highly divergent RfaH orthologs from pathogenic proteobacteria can substitute for Escherichia coli RfaH both in vivo and in vitro

In silico discovery of small molecules that inhibit RfaH recruitment to RNA polymerase

Initial events in bacterial transcription initiation ⬇️

Interdomain Contacts Control Native State Switching of RfaH on a Dual-Funneled Landscape

Interdomain contacts control folding of transcription factor RfaH.

Interplay between the trigger loop and the F loop during RNA polymerase catalysis

Interplay of DNA repair with transcription: from structures to mechanisms

Is it easy to stop RNA polymerase?

Locking the nontemplate DNA to control transcription

Maintenance of Transcription-Translation Coupling by Elongation Factor P.

Mechanism of chromatin remodeling and recovery during passage of RNA polymerase II.

Modulation of RNA polymerase activity through the trigger loop folding ⬇️

Multiple roles of the RNA polymerase {beta}' SW2 region in transcription initiation, promoter escape, and RNA elongation

Nucleotide excision repair (NER) machinery recruitment by the transcription-repair coupling factor involves unmasking of a conserved intramolecular interface

NusG-Spt5 Proteins—Universal Tools for Transcription Modification and Communication ⬇️

Origins and Molecular Evolution of the NusG Paralog RfaH

Post-initiation control by the initiation factor sigma

Purification of bacterial RNA polymerase: tools and protocols

RNA polymerase gate loop guides the nontemplate DNA strand in transcription complexes.

Rebuilding the bridge between transcription and translation

Regulation of Transcript Elongation

Regulation through the RNA polymerase secondary channel. Structural and functional variability of the coiled-coil transcription factors

Response to Klyuyev and Vassylyev: on the mechanism of tagetitoxin inhibition of transcription

Role of a Zn-independent DksA in Zn homeostasis and stringent response

Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase ρ

Structural Basis for Converting a General Transcription Factor into an Operon-Specific Virulence Regulator

Structural basis for substrate loading in bacterial RNA polymerase

Structural basis for transcription elongation by bacterial RNA polymerase

Structural basis for transcription inhibition by tagetitoxin

Tagetitoxin inhibits RNA polymerase through trapping of the trigger loop

Termination and antitermination: RNA polymerase runs a stop sign ⬇️

The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation

The carboxy-terminal coiled-coil of the RNA polymerase β′-subunit is the main binding site for Gre factors

The dormancy-specific regulator, SutA, is intrinsically disordered and modulates transcription initiation in Pseudomonas aeruginosa

The elongation factor RfaH and the initiation factor sigma bind to the same site on the transcription elongation complex

The β Subunit Gate Loop Is Required for RNA Polymerase Modification by RfaH and NusG ⬇️

The δ subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling

Transcription inactivation through local refolding of the RNA polymerase structure

Transcription initiation factor DksA has diverse effects on RNA chain elongation ⬇️

Transcription termination control of the S box system: direct measurement of S-adenosylmethionine by the leader RNA.

Transcriptional pausing coordinates folding of the aptamer domain and the expression platform of a riboswitch ⬇️

Transformation: the next level of regulation

Ubiquitous transcription factors display structural plasticity and diverse functions: NusG proteins - Shifting shapes and paradigms

pH dependence of the stress regulator DksA