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List of works by Sébastien Dutertre

A Recurrent Motif: Diversity and Evolution of ShKT Domain Containing Proteins in the Vampire Snail

scientific article published on 12 February 2019

A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis.

scientific article published on 17 July 2015

AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity

scientific article

Australian funnel-web spiders evolved human-lethal δ-hexatoxins for defense against vertebrate predators

scientific article published on 21 September 2020

Backbone Cyclization Turns a Venom Peptide into a Stable and Equipotent Ligand at Both Muscle and Neuronal Nicotinic Receptors

scientific article published on 16 October 2020

Beta2 subunit contribution to 4/7 alpha-conotoxin binding to the nicotinic acetylcholine receptor

scientific article published in June 2005

Characterisation of a Novel A-Superfamily Conotoxin

scientific article published on 20 May 2020

Chemical synthesis of MT1 and MT7 muscarinic toxins: critical role of Arg-34 in their interaction with M1 muscarinic receptor.

scientific article

Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus.

scientific article published on 31 August 2015

Comparative proteomic study of the venom of the piscivorous cone snail Conus consors

scientific article

Computational approaches to understand alpha-conotoxin interactions at neuronal nicotinic receptors

scientific article published on June 2004

Cone snail venomics: from novel biology to novel therapeutics

scientific article

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

scientific article

Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides

scientific article published on 2 January 2008

Conotoxin Φ-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity

scientific article published on 5 October 2017

Conotoxins: Chemistry and Biology

scientific article published on 21 October 2019

Conus Venom Peptide Pharmacology ⬇️

scientific article published on March 8, 2012

Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom

scientific article

Determination of alpha-conotoxin binding modes on neuronal nicotinic acetylcholine receptors.

scientific article

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

scientific article published on 7 September 2017

Discovery, synthesis, and structure-activity relationships of conotoxins.

scientific article published on 10 April 2014

Dramatic intraspecimen variations within the injected venom of Conus consors: An unsuspected contribution to venom diversity

scientific article published on 03 March 2010

Efficient binding of 4/7 α-conotoxins to nicotinic α4β2 receptors is prevented by Arg185 and Pro195 in the α4 subunit

scientific article published on 16 July 2012

Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails

scientific article

Glycine transporter dimers: evidence for occurrence in the plasma membrane

scientific article published on 5 February 2008

High-resolution picture of a venom gland transcriptome: case study with the marine snail Conus consors

scientific article

Inhibitory glycine receptors: an update

scientific article

Intraspecific variations in Conus geographus defence-evoked venom and estimation of the human lethal dose.

scientific article published on 7 October 2014

Intraspecific variations in Conus purpurascens injected venom using LC/MALDI-TOF-MS and LC-ESI-TripleTOF-MS.

scientific article published on 6 June 2015

Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor.

scientific article

Isolation and characterisation of conomap-Vt, a D-amino acid containing excitatory peptide from the venom of a vermivorous cone snail.

scientific article published on 16 June 2006

Large-scale discovery of conopeptides and conoproteins in the injectable venom of a fish-hunting cone snail using a combined proteomic and transcriptomic approach

scientific article published on 13 June 2012

Miniaturized bioaffinity assessment coupled to mass spectrometry for guided purification of bioactives from toad and cone snail

scientific article

Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function

scientific article published in September 2008

MrIC, a novel α-conotoxin agonist in the presence of PNU at endogenous α7 nicotinic acetylcholine receptors

scientific article published on 30 December 2013

Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides

scientific article published in Scientific Reports

PH-domain-driven targeting of collybistin but not Cdc42 activation is required for synaptic gephyrin clustering.

scientific article published on 19 March 2010

Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation - Suggestion of a Binding Mode at the α7 nAChR

scientific article published on 31 May 2019

Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors).

scientific article

Probing the pharmacological properties of distinct subunit interfaces within heteromeric glycine receptors reveals a functional ββ agonist-binding site

scientific article

Proteomic insight into the venom composition of the largest European rear-fanged snake, Malpolon monspessulanus monspessulanus

scientific article published in 2022

Proteotranscriptomic Insights into the Venom Composition of the Wolf Spider Lycosa tarantula

scientific article published on 05 August 2020

Quantifying Ca2+ current and permeability in ATP-gated P2X7 receptors.

scientific article

Recruitment of glycosyl hydrolase proteins in a cone snail venomous arsenal: further insights into biomolecular features of Conus venoms

scientific article published on 31 January 2012

Structure of the O-glycosylated conopeptide CcTx from Conus consors venom

scientific article

Synthesis, Pharmacological and Structural Characterization of Novel Conopressins from Conus miliaris

scientific article published on 06 March 2020

Systematic interrogation of the Conus marmoreus venom duct transcriptome with ConoSorter reveals 158 novel conotoxins and 13 new gene superfamilies

scientific article

Towards an integrated venomics approach for accelerated conopeptide discovery

scientific article published on 28 April 2012

Toxin insights into nicotinic acetylcholine receptors

scientific article

Transcriptome and proteome of Conus planorbis identify the nicotinic receptors as primary target for the defensive venom.

scientific article published on 28 October 2015

Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity

scientific article published on 16 September 2013

Transcriptomic-Proteomic Correlation in the Predation-Evoked Venom of the Cone Snail,

scientific article published on 19 March 2019

Unravelling the complex venom landscapes of lethal Australian funnel-web spiders (Hexathelidae: Atracinae) using LC-MALDI-TOF mass spectrometry.

scientific article

Use of venom peptides to probe ion channel structure and function

scientific article

Venomics Reveals Venom Complexity of the Piscivorous Cone Snail,

scientific article published on 21 January 2019

Venomics in medicinal chemistry

scientific article published in October 2014

Venomics of the asp viper Vipera aspis aspis from France

scientific article published on 19 February 2020

α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors.

scientific article

δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails

scientific article (publication date: 22 July 2015)

χ-Conotoxin and Tricyclic Antidepressant Interactions at the Norepinephrine Transporter Define a New Transporter Model

scientific article published in Journal of Biological Chemistry

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