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List of works by Saïk Urien

A CT scan protocol for the detection of radiographic loosening of the glenoid component after total shoulder arthroplasty

scientific article

A Population Pharmacokinetic/Pharmacodynamic Model Predicts Favorable HDL Cholesterol Changes Over the First 5 Years in Children Treated With Current Efavirenz-Based Regimens

scientific article published on 8 January 2016

Acetazolamide: a second wind for a respiratory stimulant in the intensive care unit?

scientific article

Age-related effects on nelfinavir and M8 pharmacokinetics: a population study with 182 children

scientific article

An optimized ibuprofen dosing scheme for preterm neonates with patent ductus arteriosus, based on a population pharmacokinetic and pharmacodynamic study

scientific article

Anti-factor Xa kinetics after intravenous enoxaparin in patients undergoing percutaneous coronary intervention: a population model analysis

scientific article published in October 2005

Assessment of Nevirapine Prophylactic and Therapeutic Dosing Regimens for Neonates

scientific article published on 9 May 2017

Challenges regarding analysis of unbound fraction of highly bound protein antiretroviral drugs in several biological matrices: lack of harmonisation and guidelines

scientific article

Concentrations of tenofovir and emtricitabine in breast milk of HIV-1-infected women in Abidjan, Cote d'Ivoire, in the ANRS 12109 TEmAA Study, Step 2

scientific article

Contribution of different antiretroviral regimens containing zidovudine, lamivudine and ritonavir-boosted lopinavir on HIV viral load reduction during pregnancy

scientific article

Determination of optimal vitamin D3 dosing regimens in HIV-infected paediatric patients using a population pharmacokinetic approach

scientific article

Developmental pharmacokinetics of lamivudine in 580 pediatric patients ranging from neonates to adolescents ⬇️

scientific article

Didanosine population pharmacokinetics in West African human immunodeficiency virus-infected children administered once-daily tablets in relation to efficacy after one year of treatment

scientific article published on 06 July 2009

Efavirenz Concentrations and Probability of HIV Replication in Children

scientific article published on 29 July 2015

Emtricitabine seminal plasma and blood plasma population pharmacokinetics in HIV-infected men in the EVARIST ANRS-EP 49 study

scientific article

Evaluation of effect of impaired renal function on lamivudine pharmacokinetics

scientific article

Evaluation of nevirapine dosing recommendations in HIV-infected children

scientific article published on July 2013

Impact of body weight and missed doses on lopinavir concentrations with standard and increased lopinavir/ritonavir doses during late pregnancy

scientific article

Influence of body weight on achieving indinavir concentrations within its therapeutic window in HIV-infected Thai patients receiving indinavir boosted with ritonavir

scientific article

Is the recommended dose of efavirenz optimal in young West African human immunodeficiency virus-infected children?

scientific article published on 27 July 2009

Is the recommended once-daily dose of lamivudine optimal in West African HIV-infected children?

scientific article

Lopinavir/ritonavir population pharmacokinetics in neonates and infants

scientific article

Maternal and fetal zidovudine pharmacokinetics during pregnancy and labour: too high dose infused at labour?

scientific article

Modeling for critically ill patients: An introduction for beginners

scientific article

Modeling of In-Utero and Intra-Partum Transmissions to Evaluate the Efficacy of Interventions for the Prevention of Perinatal HIV.

scientific article published on 19 May 2015

Modeling the effectiveness of nebulized terbutaline for decompensated chronic obstructive pulmonary disease patients in the emergency department

scientific article published on August 2016

Modified renal function in pregnancy: impact on emtricitabine pharmacokinetics

scientific article

No relationship between drug transporter genetic variants and tenofovir plasma concentrations or changes in glomerular filtration rate in HIV-infected adults

scientific article

Optimization of the strength of the efavirenz/lamivudine/abacavir fixed-dose combination for paediatric patients

scientific article published on 24 October 2016

Oxaliplatin plus irinotecan and FU-FOL combination and pharmacokinetic analysis in advanced colorectal cancer patients

scientific article

Pharmacokinetic modelling of the placental transfer of nelfinavir and its M8 metabolite: a population study using 75 maternal-cord plasma samples

scientific article

Pharmacokinetics and Toxicity in Rats and Monkeys of coDbait: A Therapeutic Double-stranded DNA Oligonucleotide Conjugated to Cholesterol

scientific article

Pharmacokinetics and virological efficacy after switch to once-daily lopinavir-ritonavir in treatment-experienced HIV-1-infected children

scientific article

Pharmacokinetics of epinephrine in patients with septic shock: modelization and interaction with endogenous neurohormonal status

scientific article published on 21 July 2009

Pharmacokinetics, hemodynamic and metabolic effects of epinephrine to prevent post-operative low cardiac output syndrome in children

scientific article

Phase I dose-escalation study of EZN-2208 (PEG-SN38), a novel conjugate of poly(ethylene) glycol and SN38, administered weekly in patients with advanced cancer

scientific article published on 30 March 2013

Physiologically-based pharmacokinetic modeling of renally excreted antiretroviral drugs in pregnant women

scientific article

Plasma and intracellular tenofovir pharmacokinetics in the neonate (ANRS 12109 trial, step 2)

scientific article

Plasma and intraprostatic concentrations of ertapenem following preoperative single dose administration: a single-centre prospective experience and clinical implications-the ERTAPRO study

scientific article published on 2 June 2016

Population Pharmacokinetic Modeling of Tenofovir in the Genital Tract of Male HIV-Infected Patients

scientific article published on 12 December 2016

Population Pharmacokinetics of Nevirapine in HIV-1-Infected Pregnant Women and Their Neonates ⬇️

scientific article published on October 18, 2010

Population analysis of weight-, age-, and sex-related differences in the pharmacokinetics of lopinavir in children from birth to 18 years

scientific article

Population approach to analyze the pharmacokinetics of free and total lopinavir in HIV-infected pregnant women and consequences for dose adjustment

scientific article

Population pharmacodynamic model of bicarbonate response to acetazolamide in mechanically ventilated chronic obstructive pulmonary disease patients

scientific article published on 14 September 2011

Population pharmacodynamic modeling and simulation of the respiratory effect of acetazolamide in decompensated COPD patients

scientific article (publication date: 2014)

Population pharmacokinetics and bioavailability of tacrolimus in kidney transplant patients

scientific article

Population pharmacokinetics and exploratory pharmacodynamics of ifosfamide according to continuous or short infusion schedules: an n = 1 randomized study

scientific article published on 21 February 2008

Population pharmacokinetics and haemodynamic effects of norepinephrine in hypotensive critically ill children

scientific article

Population pharmacokinetics and pharmacodynamics of cysteamine in nephropathic cystinosis patients

scientific article published on 23 December 2011

Population pharmacokinetics of abacavir in pregnant women

scientific article

Population pharmacokinetics of atazanavir/ritonavir in HIV-1-infected children and adolescents

scientific article published on December 2011

Population pharmacokinetics of clindamycin orally and intravenously administered in patients with osteomyelitis

scientific article published in December 2012

Population pharmacokinetics of emtricitabine in HIV-1-infected adult patients

scientific article

Population pharmacokinetics of emtricitabine in human immunodeficiency virus type 1-infected pregnant women and their neonates

scientific article published on 22 December 2008

Population pharmacokinetics of tenofovir in human immunodeficiency virus-infected patients taking highly active antiretroviral therapy

scientific article published in August 2005

Population pharmacokinetics study of recommended zidovudine doses in HIV-1-infected children

scientific article published on 22 July 2013

Prediction of drug clearance in children

scientific article published on 25 May 2015

Prediction of human fetal pharmacokinetics using ex vivo human placenta perfusion studies and physiologically based models

scientific article published on 31 October 2015

Pregnancy-related effects on lamivudine pharmacokinetics in a population study with 228 women

scientific article published on 21 November 2011

Pregnancy-related effects on nelfinavir-M8 pharmacokinetics: a population study with 133 women

scientific article

Pregnancy-related effects on tenofovir pharmacokinetics: a population study with 186 women

scientific article published on 28 November 2011

Prehospital treatment with levetiracetam plus clonazepam or placebo plus clonazepam in status epilepticus (SAMUKeppra): a randomised, double-blind, phase 3 trial

scientific article

Prospective assessment and histological analysis of adherent perinephric fat in partial nephrectomies

scientific article published on 27 October 2016

Very high concentrations of active intracellular phosphorylated emtricitabine in neonates (ANRS 12109 trial, step 2).

scientific article

Vitamin D3 supplementation scheme in HIV-infected patients based upon pharmacokinetic modelling of 25-hydroxycholecalciferol

scientific article published on May 2013

Weekly administration of paclitaxel: theoretical and clinical basis

scientific article

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