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List of works by Christopher Linington

A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease

scientific article published on 01 December 1987

A permanent rat T cell line that mediates experimental allergic neuritis in the Lewis rat in vivo

scientific article

Accessibility of galactosyl ceramides to probe reagents in central nervous system myelin

scientific article published on 01 October 1980

Activated non-neural specific T cells open the blood-brain barrier to circulating antibodies

scientific article

Analysis of interleukin-4 receptor alpha chain variants in multiple sclerosis

scientific article published on 01 February 2001

Animal models

scientific article published on 01 January 1994

Animal models of demyelination

scientific article published in July 1996

Anti-MOG and anti-MBP antibody subclasses in multiple sclerosis

scientific article published on 01 October 2001

Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study

article

Antibodies to MOG in NMO: a seasoned veteran finds a new role

scientific article published on 22 August 2012

Antibodies to myelin-oligodendrocyte glycoprotein in cerebrospinal fluid from patients with multiple sclerosis and controls

scientific article published on 01 February 1991

Antibody cross-reactivity between myelin oligodendrocyte glycoprotein and the milk protein butyrophilin in multiple sclerosis.

scientific article

Antibody facilitation of multiple sclerosis-like lesions in a nonhuman primate.

scientific article published on December 1995

Antibody responses in chronic relapsing experimental allergic encephalomyelitis: correlation of serum demyelinating activity with antibody titre to the myelin/oligodendrocyte glycoprotein (MOG).

scientific article published in December 1987

Antibody-mediated demyelination in experimental allergic encephalomyelitis is independent of complement membrane attack complex formation

scientific article published in February 1991

Antigen presentation in the peripheral nervous system: Schwann cells present endogenous myelin autoantigens to lymphocytes

scientific article published on December 1986

Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein

scientific article published in March 1988

Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology

scientific article published in October 1998

Axo-glial antigens as targets in multiple sclerosis: implications for axonal and grey matter injury.

scientific article published on 06 May 2010

B cell antigen presentation is sufficient to drive neuroinflammation in an animal model of multiple sclerosis

scientific article published on 20 April 2015

B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity

scientific article

Butyrophilin, a milk protein, modulates the encephalitogenic T cell response to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis.

scientific article

Changes in the metabolism of glial fibrillary acid protein (GFAP) during chronic relapsing experimental allergic encephalomyelitis in the strain 13 guinea-pig

scientific article

Commentary: Sorting the wheat from the chaff: identifying demyelinating components of the myelin oligodendrocyte glycoprotein (MOG)-specific autoantibody repertoire

scientific article published on 01 August 2004

Conduction failure and nerve conduction slowing in experimental allergic neuritis induced by P2-specific T-cell lines

scientific article published in January 1986

Conservation of the carboxyl terminal epitope of myelin proteolipid protein in the tetrapods and lobe-finned fish

scientific article published on 01 April 1990

Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals

scholarly article

Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatibility complex (MHC) haplotype-related.

scientific article published in December 2006

DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis

scientific article published on 16 April 2008

Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis

scientific article published on 01 January 2004

Demyelinating myelin oligodendrocyte glycoprotein-specific autoantibody response is focused on one dominant conformational epitope region in rodents

scientific article

Developmental changes in rat sciatic nerve myelin

scientific article published in February 1981

Disease progression in chronic relapsing experimental allergic encephalomyelitis is associated with reduced inflammation-driven production of corticosterone.

scientific article published in August 2001

Electrophysiological follow up of experimental allergic neuritis mediated by a permanent T cell line in rats

scientific article published on 01 January 1988

Encephalitogenic and neuritogenic T cell responses to the myelin-associated glycoprotein (MAG) in the Lewis rat.

scientific article published in March 1999

Epitope specificity of demyelinating monoclonal autoantibodies directed against the human myelin oligodendrocyte glycoprotein (MOG).

scientific article published in June 1999

Experimental allergic encephalomyelitis: the balance between encephalitogenic T lymphocytes and demyelinating antibodies determines size and structure of demyelinated lesions.

scientific article published in January 1988

Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100 beta molecule, a calcium binding protein of astroglia.

scientific article published in September 1994

Fc Receptors are Critical for Autoimmune Inflammatory Damage to the Central Nervous System in Experimental Autoimmune Encephalomyelitis

scientific article published on 01 January 2002

Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9.

scientific article published on 22 April 2015

Functional duality of astrocytes in myelination

scientific article published in September 2011

Galactosyl ceramides of the myelin sheath: thermal studies

scientific article published on 01 January 1981

Genetic linkage analysis of the antibody responses to myelin basic protein and myelin oligodendrocyte glycoprotein in rats immunized with rat spinal cord homogenate

scientific article published on 01 July 2001

Genetic variation in myelin oligodendrocyte glycoprotein expression and susceptibility to experimental autoimmune encephalomyelitis

scientific article published on 01 June 2003

Heat shock proteins and the immunopathogenesis of multiple sclerosis.

scientific article published in December 1995

IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages.

scientific article

Identification of a common idiotype on myelin oligodendrocyte glycoprotein-specific autoantibodies in chronic relapsing experimental allergic encephalomyelitis

scientific article published on 01 July 1989

Identification of an encephalitogenic determinant of myelin proteolipid protein for the rabbit

scientific article published on 01 December 1990

Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice

scientific article published on 01 November 1994

Immunohistochemical localisation of terminal complement component C9 in experimental allergic encephalomyelitis

scientific article published in January 1989

Increased reactivity to myelin oligodendrocyte glycoprotein peptides and epitope mapping in HLA DR2(15)+ multiple sclerosis

scientific article published on 01 October 1998

Induction of autoimmune reactions to myelin basic protein in measles virus encephalitis in Lewis rats

scientific article published in January 1988

Induction of experimental allergic neuritis in the BN rat: P2 protein-specific T cells overcome resistance to actively induced disease

scientific article published in December 1986

Inhibition of autoimmune encephalomyelitis by a tetracycline.

scientific article

Interferon-γ potentiates antibody-mediated demyelination in vivo

scientific article published on 01 August 1992

Investigation of myelin/oligodendrocyte glycoprotein membrane topology

scientific article published on 01 November 1996

Late complications of immune deviation therapy in a nonhuman primate

scientific article published in December 1996

Linkage Analysis of Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis in the Rat Identifies a Locus Controlling Demyelination on Chromosome 18

scientific article published on 01 November 1999

Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis ⬇️

scientific article published on August 26, 2011

Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination

scientific article

Localization of cerebroside in central-nervous-system myelin lamellae: an initial approach

scientific article published on 01 January 1977

MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

scientific article published on 09 December 2013

MHC class II-regulated central nervous system autoaggression and T cell responses in peripheral lymphoid tissues are dissociated in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis

scientific article

MHC gene related effects on microglia and macrophages in experimental autoimmune encephalomyelitis determine the extent of axonal injury.

scientific article published in July 2002

MHC haplotype-dependent regulation of MOG-induced EAE in rats.

scientific article published on September 1998

MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated

scientific article

Maternal neurofascin-specific autoantibodies bind to structures of the fetal nervous system during pregnancy, but have no long term effect on development in the rat.

scientific article published on 20 January 2014

Microglial involvement in experimental autoimmune inflammation of the central and peripheral nervous system.

scientific article

Molecular mimicry and the autoimmune response to the peripheral nerve myelin P0 glycoprotein.

scientific article published on September 1992

Morphologic study on experimental allergic neuritis mediated by T cell line specific for bovine P2 protein in Lewis rats.

scientific article published in August 1985

Multiple sclerosis: B- and T-cell responses to the extracellular domain of the myelin oligodendrocyte glycoprotein.

scientific article

Myelin oligodendrocyte glycoprotein is expressed in the peripheral nervous system of rodents and primates

scientific article

Myelin oligodendrocyte glycoprotein-DNA vaccination induces antibody-mediated autoaggression in experimental autoimmune encephalomyelitis

scientific article published on 01 December 2000

Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

scientific article

Myelin-oligodendrocyte glycoprotein (MOG) is a surface marker of oligodendrocyte maturation

scientific article published on 01 May 1989

Myelin/oligodendrocyte glycoprotein is a unique member of the immunoglobulin superfamily.

scientific article

Myelinating Cultures: An In Vitro Tool to Identify Demyelinating and Axopathic Autoantibodies

scientific article published on January 2016

Neurofascin 186 specific autoantibodies induce axonal injury and exacerbate disease severity in experimental autoimmune encephalomyelitis

scientific article published on 18 May 2013

Neurofascin as a novel target for autoantibody-mediated axonal injury

scientific article

Neurofascin as a target for autoantibodies in peripheral neuropathies

scientific article published on 24 October 2012

Neurological deficits caused by tissue hypoxia in neuroinflammatory disease

scientific article published on 17 October 2013

Neuronal expression of fractalkine in the presence and absence of inflammation.

scientific article published in November 1998

Normal rat serum cytotoxicity against syngeneic oligodendrocytes. Complement activation and attack in the absence of anti-myelin antibodies.

scientific article published in February 1989

Novel Tcr Tcra-V and -J transcripts expressed in rat myelin-specific T-cell lines.

scientific article published on January 1993

On the Accessibility and Localisation of Cerebrosides in Central Nervous System Myelin ⬇️

scientific article published on January 1, 1978

Organ specific autoantigens and the autoreactiveT cell repertoire: the case of myelin oligodendrocyte glycoprotein

scientific article published on 01 March 2006

Peripheral nervous system myelin assembly in vitro: perturbation by the ionophore monensin

scientific article published on 01 August 1983

Polarizing receptor activation dissociates fibroblast growth factor 2 mediated inhibition of myelination from its neuroprotective potential

scientific article published on 19 December 2019

Production and characterization of monoclonal antibodies to the extracellular domain of P0.

scientific article

Protracted, relapsing and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete Freund's adjuvant

scientific article published on 01 December 1995

Quantitative trait loci disposing for both experimental arthritis and encephalomyelitis in the DA rat; impact on severity of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis and antibody isotype pattern

scientific article published in July 1998

Re-expression of N-cadherin in remyelinating lesions of experimental inflammatory demyelination

scientific article

Resistance is futile: antineuronal autoimmunity in multiple sclerosis

scientific article published on 07 January 2008

Selective and antigen-dependent effects of myelin degeneration on central nervous system inflammation

scientific article published on 01 December 2004

Selective unresponsiveness to conformational B cell epitopes of the myelin oligodendrocyte glycoprotein in H-2b mice

scientific article published on 01 July 2003

Serum autoantibody responses to myelin oligodendrocyte glycoprotein and myelin basic protein in X-linked adrenoleukodystrophy and multiple sclerosis

scientific article published on 01 September 2001

Spinal cord microglia in experimental allergic neuritis. Evidence for fast and remote activation

scientific article published on 01 July 1992

Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein

scientific article

Susceptibility and resistance to experimental allergic encephalomyelitis: relationship with hypothalamic-pituitary-adrenocortical axis responsiveness in the rat.

scientific article

Synergism in the pathogenesis of EAE induced by an MBP-specific T-cell line and monoclonal antibodies to galactocerebroside or a myelin oligodendroglial glycoprotein

scientific article published in January 1988

T and B cell responses to myelin-oligodendrocyte glycoprotein in multiple sclerosis

scientific article published on 01 March 1991

T cell responses to myelin proteins in Guillain-Barré syndrome.

scientific article

T cells specific for the myelin oligodendrocyte glycoprotein mediate an unusual autoimmune inflammatory response in the central nervous system.

scientific article published on June 1993

T lymphocyte autoimmunity in peripheral nervous system autoimmune disease

scientific article published on 01 December 1986

T lymphocyte recognition sites on peripheral nerve myelin P0 protein ⬇️

scientific article published on October 1, 1994

T-cell apoptosis in inflammatory brain lesions: destruction of T cells does not depend on antigen recognition

scientific article published on September 1998

T-cell mediated autoimmunity: molecular interactions and therapeutic implications

scientific article published on 01 August 1990

The B cell repertoire in experimental allergic neuritis involves multiple myelin proteins and GM1

scientific article published on 01 September 1994

The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat

scientific article published on 01 December 1995

The T-cell receptor in multiple sclerosis.

scientific article published on July 1995

The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis

scientific article published in January 2004

The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens

scientific article published on 28 October 2014

The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement.

scientific article published on August 1993

The fine specificity of the myelin oligodendrocyte glycoprotein autoantibody response in patients with multiple sclerosis and normal healthy controls

article

The glycoprotein composition of peripheral nervous system myelin subfractions

scientific article published on 01 April 1981

The immune response to myelin proteolipid protein in the Lewis rat: identification of the immunodominant B cell epitope

scientific article published on 01 May 1990

The in vivo synthesis of myelin proteins in rabbit sciatic nerve

scientific article

The lipid and glycoprotein composition of peripheral-nervous-system myelin subfractions isolated by zonal centrifugation [proceedings]

scientific article published on 01 February 1980

The lipid composition of light and heavy myelin subfractions isolated from rabbit sciatic nerve

scientific article published on 01 November 1980

The role of CD8(+) T cells in a model of multiple sclerosis induced with recombinant myelin oligodendrocyte glycoprotein.

scientific article published on 27 September 2011

The role of complement in the pathogenesis of experimental allergic encephalomyelitis

scientific article published on 01 August 1989

The role of macrophages in experimental autoimmune neuritis induced by a P2-specific T-cell line

scientific article published in April 1988

The shaping of the brain-specific T lymphocyte repertoire in the thymus.

scientific article published on February 1996

Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination.

scientific article published on 11 December 2014

Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.

scientific article

Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement

scientific article published in Nature

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