List of works - Julia Horsfield

A DNA Contact Map for the Mouse Runx1 Gene Identifies Novel Haematopoietic Enhancers

scientific article published on 17 October 2017

A DNA Contact Map for the Mouse Runx1 Gene Identifies Novel Hematopoietic Enhancers

article

A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila.

scientific article

A neural crest origin for cohesinopathy heart defects

scientific article

A non-coding genetic variant associated with abdominal aortic aneurysm alters ERG gene regulation

scientific article published on 01 March 2020

A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression

scholarly article

A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression

scientific article published on 1 November 2018

A variant of the castor zinc finger 1 (CASZ1) gene is differentially associated with the clinical classification of chronic venous disease

scientific article published on 30 September 2019

A zebrafish model of Roberts syndrome reveals that Esco2 depletion interferes with development by disrupting the cell cycle

scientific article

Abstract 4518: 4CSeq analysis of a breast cancer susceptibility locus on 6q25.1

An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations

scientific article

Antioxidant treatment ameliorates phenotypic features of SMC1A-mutated Cornelia de Lange syndrome in vitro and in vivo

scientific article published on 01 September 2018

BET inhibition prevents aberrant RUNX1 and ERG transcription in STAG2 mutant leukaemia cells

scientific article published on 03 January 2020

Base-resolution DNA methylation landscape of zebrafish brain and liver

scientific article

Cadherin-17 is required to maintain pronephric duct integrity during zebrafish development.

scientific article

Chlorogenic Acid Supplementation Benefits Zebrafish Embryos Exposed to Auranofin

scientific article published on 11 December 2020

Cohesin Components Stag1 and Stag2 Differentially Influence Haematopoietic Mesoderm Development in Zebrafish Embryos

scientific article published on 07 December 2020

Cohesin Mutations in Cancer: Emerging Therapeutic Targets

scientific article published on 24 June 2021

Cohesin and CTCF differentially regulate spatiotemporal runx1 expression during zebrafish development.

scientific article published on 07 December 2013

Cohesin facilitates zygotic genome activation in zebrafish

Cohesin facilitates zygotic genome activation in zebrafish.

scientific article published on 20 November 2017

Cohesin is required for activation of MYC by estradiol

scientific article

Cohesin modulates transcription of estrogen-responsive genes.

scientific article published on 24 December 2014

Cohesin mutations are synthetic lethal with stimulation of WNT signaling

scientific article published on 07 December 2020

Cohesin mutations in myeloid malignancies: underlying mechanisms

scientific article

Cohesin-dependent regulation of Runx genes

scientific article published on 13 June 2007

Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016.

scientific article published on 12 February 2017

Cornelia de Lange syndrome, related disorders, and the Cohesin complex: Abstracts from the 8th biennial scientific and educational symposium 2018

scientific article published on 15 March 2019

Cornelia de Lange syndrome: further delineation of phenotype, cohesin biology and educational focus, 5th Biennial Scientific and Educational Symposium abstracts

scientific article published on 6 February 2014

Corrigendum: Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs LINC01229 and MAFTRR

scientific article published on 24 April 2019

Dietary Intake Influences Adult Fertility and Offspring Fitness in Zebrafish

scientific article

Diverse developmental disorders from the one ring: distinct molecular pathways underlie the cohesinopathies

scientific article published on 12 September 2012

Drosophila cyclin E interacts with components of the Brahma complex

scientific article

Embryonic oxidative stress results in reproductive impairment for adult zebrafish.

scientific article

Expression of cohesin and condensin genes during zebrafish development supports a non-proliferative role for cohesin

scientific article published on 31 August 2009

Full circle: a brief history of cohesin and the regulation of gene expression

scientific article published on 31 January 2022

Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs and

scientific article published on 1 January 2018

GWAS on prolonged gestation (post-term birth): analysis of successive Finnish birth cohorts

scientific article

Gene regulation by cohesin in cancer: is the ring an unexpected party to proliferation?

scientific article published on 22 September 2011

Genetic Variation as a Long-Distance Modulator of RAD21 Expression in Humans

scientific article published on 28 May 2021

Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control

scientific article published on 27 January 2020

HDAC8 Inhibition Blocks SMC3 Deacetylation and Delays Cell Cycle Progression without Affecting Cohesin-dependent Transcription in MCF7 Cancer Cells

scientific article published on 12 April 2016

Histological and transcriptomic effects of 17α-methyltestosterone on zebrafish gonad development

scientific article published on 24 July 2017

Identification of sex differences in zebrafish (Danio rerio) brains during early sexual differentiation and masculinisation using 17α-methyltestoterone

scientific article published on 20 December 2017

In situ hybridization screen in zebrafish for the selection of genes encoding secreted proteins.

scientific article

Insights from space: potential role of diet in the spatial organization of chromosomes

scientific article

Intergenic GWAS SNPs are key components of the spatial and regulatory network for human growth.

scientific article published on 10 June 2016

Investigation of the Use of Impermeable Fluid Barriers between Pelleted and Supernatant Enzyme Activity in a Pseudohomogeneous Enzyme Immunoassay

scientific article published on 01 September 1992

Leptin regulates glucose homeostasis via the canonical WNT pathway

scientific article published on 17 February 2021

Leptin regulates glucose homeostasis via the canonical Wnt pathway in the zebrafish

scientific article published on 21 February 2022

Long distance relationships: Enhancer–promoter communication and dynamic gene transcription ⬇️

scientific article published on November 1, 2012

Low tolerance for transcriptional variation at cohesin genes is accompanied by functional links to disease-relevant pathways

scientific article published on 11 September 2020

Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing

scientific article

Packaging development: how chromatin controls transcription in zebrafish embryogenesis

scientific article published on 05 April 2019

Pathways in blood and vessel development revealed through zebrafish genetics.

scientific article

Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved

scientific article

RAD21 mutations cause a human cohesinopathy

scientific article

Regulation of the interferon-gamma (IFN-γ) pathway by p63 and Δ133p53 isoform in different breast cancer subtypes

scientific article published on 26 June 2018

Riboceine Rescues Auranofin-Induced Craniofacial Defects in Zebrafish

scientific article published on 8 December 2021

Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.

scientific article

Runx3 is required for hematopoietic development in zebrafish

scientific article

SMAD proteins directly suppress PAX2 transcription downstream of transforming growth factor-beta 1 (TGF-β1) signalling in renal cell carcinoma.

scientific article published in June 2018

Sex differences in DNA methylation and expression in zebrafish brain: a test of an extended 'male sex drive' hypothesis ⬇️

scientific article published on 31 May 2016

The three-dimensional genome in zebrafish development

scientific article published on 2 March 2021

Transcriptional Regulation of : An Informatics Analysis

scientific article published on 29 July 2021

List of works by Julia Horsfield

A DNA Contact Map for the Mouse Runx1 Gene Identifies Novel Haematopoietic Enhancers

A DNA Contact Map for the Mouse Runx1 Gene Identifies Novel Hematopoietic Enhancers

A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila.

A neural crest origin for cohesinopathy heart defects

A non-coding genetic variant associated with abdominal aortic aneurysm alters ERG gene regulation

A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression

A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression

A variant of the castor zinc finger 1 (CASZ1) gene is differentially associated with the clinical classification of chronic venous disease

A zebrafish model of Roberts syndrome reveals that Esco2 depletion interferes with development by disrupting the cell cycle

Abstract 4518: 4CSeq analysis of a breast cancer susceptibility locus on 6q25.1

An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations

Antioxidant treatment ameliorates phenotypic features of SMC1A-mutated Cornelia de Lange syndrome in vitro and in vivo

BET inhibition prevents aberrant RUNX1 and ERG transcription in STAG2 mutant leukaemia cells

Base-resolution DNA methylation landscape of zebrafish brain and liver

Cadherin-17 is required to maintain pronephric duct integrity during zebrafish development.

Chlorogenic Acid Supplementation Benefits Zebrafish Embryos Exposed to Auranofin

Cohesin Components Stag1 and Stag2 Differentially Influence Haematopoietic Mesoderm Development in Zebrafish Embryos

Cohesin Mutations in Cancer: Emerging Therapeutic Targets

Cohesin and CTCF differentially regulate spatiotemporal runx1 expression during zebrafish development.

Cohesin facilitates zygotic genome activation in zebrafish

Cohesin facilitates zygotic genome activation in zebrafish.

Cohesin is required for activation of MYC by estradiol

Cohesin modulates transcription of estrogen-responsive genes.

Cohesin mutations are synthetic lethal with stimulation of WNT signaling

Cohesin mutations in myeloid malignancies: underlying mechanisms

Cohesin-dependent regulation of Runx genes

Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016.

Cornelia de Lange syndrome, related disorders, and the Cohesin complex: Abstracts from the 8th biennial scientific and educational symposium 2018

Cornelia de Lange syndrome: further delineation of phenotype, cohesin biology and educational focus, 5th Biennial Scientific and Educational Symposium abstracts

Corrigendum: Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs LINC01229 and MAFTRR

Dietary Intake Influences Adult Fertility and Offspring Fitness in Zebrafish

Diverse developmental disorders from the one ring: distinct molecular pathways underlie the cohesinopathies

Drosophila cyclin E interacts with components of the Brahma complex

Embryonic oxidative stress results in reproductive impairment for adult zebrafish.

Expression of cohesin and condensin genes during zebrafish development supports a non-proliferative role for cohesin

Full circle: a brief history of cohesin and the regulation of gene expression

Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs and

GWAS on prolonged gestation (post-term birth): analysis of successive Finnish birth cohorts

Gene regulation by cohesin in cancer: is the ring an unexpected party to proliferation?

Genetic Variation as a Long-Distance Modulator of RAD21 Expression in Humans

Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control

HDAC8 Inhibition Blocks SMC3 Deacetylation and Delays Cell Cycle Progression without Affecting Cohesin-dependent Transcription in MCF7 Cancer Cells

Histological and transcriptomic effects of 17α-methyltestosterone on zebrafish gonad development

Identification of sex differences in zebrafish (Danio rerio) brains during early sexual differentiation and masculinisation using 17α-methyltestoterone

In situ hybridization screen in zebrafish for the selection of genes encoding secreted proteins.

Insights from space: potential role of diet in the spatial organization of chromosomes

Intergenic GWAS SNPs are key components of the spatial and regulatory network for human growth.

Investigation of the Use of Impermeable Fluid Barriers between Pelleted and Supernatant Enzyme Activity in a Pseudohomogeneous Enzyme Immunoassay

Leptin regulates glucose homeostasis via the canonical WNT pathway

Leptin regulates glucose homeostasis via the canonical Wnt pathway in the zebrafish

Long distance relationships: Enhancer–promoter communication and dynamic gene transcription ⬇️

Low tolerance for transcriptional variation at cohesin genes is accompanied by functional links to disease-relevant pathways

Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing

Packaging development: how chromatin controls transcription in zebrafish embryogenesis

Pathways in blood and vessel development revealed through zebrafish genetics.

Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved

RAD21 mutations cause a human cohesinopathy

Regulation of the interferon-gamma (IFN-γ) pathway by p63 and Δ133p53 isoform in different breast cancer subtypes

Riboceine Rescues Auranofin-Induced Craniofacial Defects in Zebrafish

Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.

Runx3 is required for hematopoietic development in zebrafish

SMAD proteins directly suppress PAX2 transcription downstream of transforming growth factor-beta 1 (TGF-β1) signalling in renal cell carcinoma.

Sex differences in DNA methylation and expression in zebrafish brain: a test of an extended 'male sex drive' hypothesis ⬇️

The three-dimensional genome in zebrafish development

Transcriptional Regulation of : An Informatics Analysis

Variants at the ADAMTS13, BGALT5, SSBP2 and TKT Loci are associated with Post-term birth