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List of works by Bertrand Friguet

A convenient enzyme-linked immunosorbent assay for testing whether monoclonal antibodies recognize the same antigenic site. Application to hybridomas specific for the beta 2-subunit of Escherichia coli tryptophan synthase

scientific article published on 01 June 1983

A radioimmunoassay-based method for measuring the true affinity of a monoclonal antibody with trace amounts of radioactive antigen: illustration with the products of a cell-free protein synthesis system

scientific article published on 01 May 1993

A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms

scientific article published in April 2006

AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs

scientific article published on 10 July 2015

Age-dependent declines in proteasome activity in the heart

scientific article published in January 2002

Age-dependent protein modifications and declining proteasome activity in the human lens

scientific article

Age-related alterations of proteasome structure and function in aging epidermis

scientific article published on 01 September 2000

Age-related decline of rat liver multicatalytic proteinase activity and protection from oxidative inactivation by heat-shock protein 90

scientific article published on 01 July 1996

Age-related impairment of mitochondrial matrix aconitase and ATP-stimulated protease in rat liver and heart

scientific journal article

Age-related increase of protein glycation in peripheral blood lymphocytes is restricted to preferential target proteins

scientific article published on 01 October 2002

Aging of the dopaminergic system and motor behavior in mice intoxicated with the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

scientific article published on 11 July 2012

Aging of the liver: proteolysis of oxidatively modified glutamine synthetase

scientific article published on 01 April 1995

Algae extract protection effect on oxidized protein level in human stratum corneum

scientific article published in June 2004

Algae extract-mediated stimulation and protection of proteasome activity within human keratinocytes exposed to UVA and UVB irradiation

scientific article published on 01 January 2006

Alterations in mitochondrial and cytosolic methionine sulfoxide reductase activity during cardiac ischemia and reperfusion.

scientific article

An early immunoreactive folding intermediate of the tryptophan synthease beta 2 subunit is a 'molten globule'.

scientific article

Annonacin, a natural lipophilic mitochondrial complex I inhibitor, increases phosphorylation of tau in the brain of FTDP-17 transgenic mice

scientific article published on 03 January 2014

Anti-inflammatory and antiatherogenic effects of the NLRP3 inflammasome inhibitor arglabin in ApoE2.Ki mice fed a high-fat diet

scientific article

Autophagy impairment in muscle induces neuromuscular junction degeneration and precocious aging.

scientific article

Autosensitized oxidation of glycated bovine lens proteins irradiated with UVA-visible light at low oxygen concentration

scientific article published on 28 March 2008

CD4(+) T cell surface alpha enolase is lower in older adults

scientific article

Catalase, a target of glycation damage in rat liver mitochondria with aging

scientific article published on 07 June 2012

Cellular senescence in human keratinocytes: unchanged proteolytic capacity and increased protein load

scientific article

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

scientific article published on 7 May 2003

Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix

scientific journal article

Changes of the proteasomal system during the aging process.

scientific article published on January 2012

Characterization and role of protozoan parasite proteasomes.

scientific article published in February 2003

Chemical characterization of a protein-4-hydroxy-2-nonenal cross-link: immunochemical detection in mitochondria exposed to oxidative stress

scientific article published on 01 April 1996

Circadian modulation of proteasome activity and accumulation of oxidized protein in human embryonic kidney HEK 293 cells and primary dermal fibroblasts

scientific article published in March 2016

Clearance of genetic variants of amyloid β peptide by neuronal and non-neuronal cells

scientific article

Conformational changes in the 20S proteasome upon macromolecular ligand binding analyzed with monoclonal antibodies

scientific article published on 01 February 1999

Conformational changes induced by domain assembly within the beta 2 subunit of Escherichia coli tryptophan synthase analysed with monoclonal antibodies

scientific article

Cystathionine beta synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver.

scientific article published in May 2005

Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome

scientific article published on 05 December 2012

Dietary fatty acids and oxidative stress in the heart mitochondria

scientific article published on 05 August 2010

Differential expression and glycative damage affect specific mitochondrial proteins with aging in rat liver ⬇️

scientific article published on July 30, 2013

Effect of Lon protease knockdown on mitochondrial function in HeLa cells

scientific article published on 17 December 2013

Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice

scientific article published on 23 April 2019

Endogenous C-terminal fragments of beta-amyloid precursor protein from Xenopus laevis skin exudate

scientific article published on 12 December 2006

Enzymatic reactions involved in the repair of oxidized proteins.

scientific article published in August 2004

Epitope localization in antigen-monoclonal-antibody complexes by small-angle X-ray scattering. An approach to domain organization in the beta 2 subunit of Escherichia coli tryptophan synthase

scientific article published on 01 April 1987

Essential role of methionine residues in calmodulin binding to Bordetella pertussis adenylate cyclase, as probed by selective oxidation and repair by the peptide methionine sulfoxide reductases.

scientific article

Evidence of preferential protein targets for age-related modifications in peripheral blood lymphocytes

scientific article published in June 2004

Expression and modification proteomics during skeletal muscle ageing

scientific article published on 28 April 2013

Fibroblast cultures from healthy centenarians have an active proteasome

scientific article published on 01 September 2000

Folding on the ribosome of Escherichia coli tryptophan synthase beta subunit nascent chains probed with a conformation-dependent monoclonal antibody

scientific article published in November 1992

Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins

scientific article published on 12 January 2008

Glycation damage targets glutamate dehydrogenase in the rat liver mitochondrial matrix during aging

scientific article published on 19 October 2007

How best to halt and/or revert UV-induced skin ageing: strategies, facts and fiction.

scientific article published on March 2008

Impact of ageing on proteasome structure and function in human lymphocytes

scientific article published in May 2003

Impact of hydrogen peroxide on the activity, structure, and conformational stability of the oxidized protein repair enzyme methionine sulfoxide reductase A.

scientific article published on 30 July 2009

Impaired energy metabolism of senescent muscle satellite cells is associated with oxidative modifications of glycolytic enzymes

scientific article published on 04 December 2016

Impairment of glyoxalase-1, an advanced glycation end-product detoxifying enzyme, induced by inflammation in age-related osteoarthritis

scientific article published on 11 January 2019

Impairment of methionine sulfoxide reductase during UV irradiation and photoaging.

scientific article

Impairment of proteasome function upon UVA- and UVB-irradiation of human keratinocytes

scientific article published in June 2002

Impairment of proteasome structure and function in aging.

scientific article

Importance of residues 2-9 in the immunoreactivity, subunit interactions, and activity of the beta 2 subunit of Escherichia coli tryptophan synthase

scientific article

Improvement of Dystrophic Muscle Fragility by Short-Term Voluntary Exercise through Activation of Calcineurin Pathway in mdx Mice

scientific article published on 22 August 2018

In vitro gene expression for the localization of antigenic determinants: application to the E. coli tryptophan synthase β2 subunit ⬇️

scientific article published on February 3, 1993

Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes

scientific article published on 24 February 2006

Increased level of glycoxidation product N(epsilon)-(carboxymethyl)lysine in rat serum and urine proteins with aging: link with glycoxidative damage accumulation in kidney

scientific article published in March 2003

Inflammation and anti-tumor resistance. V. Production of a cytostatic factor following cooperation of elicited polymorphonuclear leukocytes and macrophages

scientific article published in September 1990

Inhibition of nitric oxide synthase activity by early and advanced glycation end products in cultured rabbit proximal tubular epithelial cells

scientific article

Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein

scientific article published on 01 March 1997

MARK-AGE biomarkers of ageing

scientific article

Maintenance of proteins and aging: the role of oxidized protein repair.

scientific article published on December 2006

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

scientific article published on 01 March 1985

Methionine sulfoxide reductases: relevance to aging and protection against oxidative stress.

scientific article published on May 2006

Mitochondrial proteases and protein quality control in ageing and longevity

scientific article

Mitochondrial protein quality control: implications in ageing

scientific article published on June 2008

Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced glycation end products in dilated cardiomyopathy

scientific article

NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases.

scientific article

Overexpression of MsrA protects WI-38 SV40 human fibroblasts against H2O2-mediated oxidative stress.

scientific article

Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage.

scientific article

Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion

scientific article published on 25 May 2001

Oxidative proteome alterations during skeletal muscle ageing

scientific article published on 3 June 2015

Oxidative proteome modifications target specific cellular pathways during oxidative stress, cellular senescence and aging.

scientific article

Oxidative stress-induced proteome alterations target different cellular pathways in human myoblasts

scientific article

Oxidized SOD1 alters proteasome activities in vitro and in the cortex of SOD1 overexpressing mice

scientific article published in July 2005

Oxidized mitochondrial protein degradation and repair in aging and oxidative stress

scientific article published on August 2010

Oxidized protein degradation and repair in ageing and oxidative stress.

scientific article

Peptide/antibody recognition: synthetic peptides derived from the E. coli tryptophan synthase beta 2 subunit interact with high affinity with an anti-beta 2 monoclonal antibody

scientific article published on 01 April 1991

Photosensitized reactions mediated by the major chromophore arising from glucose decomposition, result in oxidation and cross-linking of lens proteins and activation of the proteasome

scientific article published on 07 December 2011

Photosensitizing Activity of Endogenous Eye Lens Chromophores: An Attempt to Unravel Their Contributions to Photo-Aging and Cataract Disease

scientific article published on 28 March 2015

Polypeptide-antibody binding mechanism: conformational adaptation investigated by equilibrium and kinetic analysis

scientific article published on 01 May 1989

Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha

scientific article published on September 2003

Prevention of dicarbonyl-mediated advanced glycation by glyoxalases: implication in skin aging

scientific article published on April 2014

Proteasome and photoaging: the effects of UV irradiation

scientific article published on 01 April 2007

Proteasome inhibition in glyoxal-treated fibroblasts and resistance of glycated glucose-6-phosphate dehydrogenase to 20 S proteasome degradation in vitro.

scientific article

Proteasomes, Sir2, and Hxk2 form an interconnected aging network that impinges on the AMPK/Snf1-regulated transcriptional repressor Mig1.

scientific article

Protein damage, repair and proteolysis.

scientific article published on 26 October 2012

Protein maintenance in aging and replicative senescence: a role for the peptide methionine sulfoxide reductases.

scientific article

Protein modification and maintenance systems as biomarkers of ageing.

scientific article

Protein modification and replicative senescence of WI-38 human embryonic fibroblasts.

scientific article

Protein oxidative damage at the crossroads of cellular senescence, aging, and age-related diseases.

scientific article published on 17 October 2012

Protein oxidative modifications and replicative senescence of WI-38 human embryonic fibroblasts.

scientific article

Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat.

scholarly article

Proteome Oxidative Modifications and Impairment of Specific Metabolic Pathways During Cellular Senescence and Aging

scientific article published on 15 October 2019

Proteome alteration in oxidative stress-sensitive methionine sulfoxide reductase-silenced HEK293 cells ⬇️

scientific article published on August 27, 2013

Proteome modulation in H9c2 cardiac cells by microRNAs miR-378 and miR-378.

scientific article published on 25 September 2013

Proteome oxidative carbonylation during oxidative stress-induced premature senescence of WI-38 human fibroblasts.

scientific article published on 27 July 2017

Proteomic quantification and identification of carbonylated proteins upon oxidative stress and during cellular aging ⬇️

scientific article published on May 18, 2013

Proteomics of muscle chronological ageing in post-menopausal women

scientific article published on 23 December 2014

Redox control of 20S proteasome.

scientific article published on January 2002

Reduced oxygen tension results in reduced human T cell proliferation and increased intracellular oxidative damage and susceptibility to apoptosis upon activation.

scientific article published on 28 September 2009

Regulation of selenoproteins and methionine sulfoxide reductases A and B1 by age, calorie restriction, and dietary selenium in mice.

scientific article

Renaturation of guanidine-unfolded tryptophan synthase by multi-mixing stopped-flow dilution in D2O.

scientific article

Response to Letter Regarding Article, "Anti-inflammatory and Antiatherogenic Effects of the Inflammasome NLRP3 Inhibitor Arglabin in ApoE2.Ki Mice Fed a High-Fat Diet".

scientific article published in November 2015

Simultaneous chemical and photochemical protein crosslinking induced by irradiation of eye lens proteins in the presence of ascorbate: the photosensitizing role of an UVA-visible-absorbing decomposition product of vitamin C.

scientific article published on 24 August 2010

Some monoclonal antibodies raised with a native protein bind preferentially to the denatured antigen

scientific article published on 01 July 1984

Structural and functional influence of enzyme-antibody interactions: effects of eight different monoclonal antibodies on the enzymatic activity of Escherichia coli tryptophan synthase

scientific article published on 01 January 1984

Subcellular localization of methionine sulphoxide reductase A (MsrA): evidence for mitochondrial and cytosolic isoforms in rat liver cells ⬇️

scientific article published on July 15, 2003

Susceptibility of glucose-6-phosphate dehydrogenase modified by 4-hydroxy-2-nonenal and metal-catalyzed oxidation to proteolysis by the multicatalytic protease

scientific article

The Oxygen Paradox, the French Paradox, and age-related diseases

scientific article

The glyoxalase enzymes are differentially localized in epidermis and regulated during ageing and photoageing

scientific article published on 12 May 2016

The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration

scientific article published on 14 August 2018

The secondary fungal metabolite gliotoxin targets proteolytic activities of the proteasome

scientific article published on 01 October 1999

The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions.

scientific article published on 2 April 2015

The ubiquitin-proteasome system at the crossroads of stress-response and ageing pathways: a handle for skin care?

scientific article

Zinc supplementation in the elderly subjects: effect on oxidized protein degradation and repair systems in peripheral blood lymphocytes.

scientific article published on 25 October 2007

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