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List of works by Karl Gademann

4-Hydroxy-2-pyridone alkaloids: structures and synthetic approaches

scientific article published on 08 June 2010

A Synthetic Entry into the Taiwaniaquinoids Based on a Biogenetic Hypothesis: Total Synthesis of (−)-Taiwaniaquinone H

scientific article published on 01 July 2010

A Unified Approach for the Stereoselective Total Synthesis of Pyridone Alkaloids and Their Neuritogenic Activity

scientific article published on 29 March 2011

A biomimetic route to the peptide alkaloid anachelin

scientific article

Aerucyclamides A and B: isolation and synthesis of toxic ribosomal heterocyclic peptides from the cyanobacterium Microcystis aeruginosa PCC 7806.

scientific article

Anguinomycins and derivatives: total syntheses, modeling, and biological evaluation of the inhibition of nucleocytoplasmic transport

scientific article published in February 2010

Antibiotic Algae by Chemical Surface Engineering

scientific article published on 12 December 2017

Antimalarial and antitubercular nostocarboline and eudistomin derivatives: synthesis, in vitro and in vivo biological evaluation

scientific article published on 11 January 2010

Antimalarial natural products of marine and freshwater origin

scientific article published on January 2009

Antimicrobial surfaces through natural product hybrids

scientific article published in January 2008

Aza-Annulation Strategies in Alkaloid Total Synthesis

Balgacyclamides, antiplasmodial heterocyclic peptides from Microcystis aeruguinosa EAWAG 251. ⬇️

scientific article published on 6 January 2014

Biohybrid Microswimmers Against Bacterial Infections

scientific article published on 10 May 2021

Biohybrid microswimmers against bacterial infections

scientific article published in December 2021

Bioinspired surfaces against bacterial infections.

scientific article

Bioinspired, releasable quorum sensing modulators

scientific article published on 20 November 2012

Biomimetic surface modifications based on the cyanobacterial iron chelator anachelin

scientific article published in February 2006

Biomimetic total synthesis and antimicrobial evaluation of anachelin H.

scientific article published on 29 September 2007

Bioorganic and bioinorganic chemistry

scientific article published in January 2010

Biosynthesis and Structure-Activity Relationship Investigations of the Diazeniumdiolate Antifungal Agent Fragin

scientific article published on 16 January 2020

Biosynthesis of fragin is controlled by a novel quorum sensing signal. ⬇️

scientific article published on 30 March 2018

Caged retinoids as photoinducible activators: implications for cell differentiation and neurite outgrowth

scientific article published on May 2013

Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis

scientific article

Catalytic Enantioselective Total Synthesis of (+)-Torrubiellone C

scientific article published on 28 July 2011

Catalytic Enantioselective Total Synthesis of (–)-Pyridovericin

Chemical Interference of Biological Systems with Natural Products ⬇️

scientific article published on January 1, 2011

Collective Syntheses of Icetexane Natural Products Based on Biogenetic Hypotheses

scientific article

Connecting C19 Norditerpenoids to C20 Diterpenes: Total Syntheses of 6-Hydroxy-5,6-dehydrosugiol, 6-Hydroxysugiol, and Taiwaniaquinone H, and Formal Synthesis of Dichroanone

Controlling Protein Transport by Small Molecules ⬇️

scientific article published on October 1, 2011

Copy, edit, and paste: natural product approaches to biomaterials and neuroengineering

scientific article published on 26 February 2015

Cyanobacterial Natural Products for the Inhibition of Biofilm Formation and Biofouling

Design and Synthesis of Metabolically Stable tRNA Synthetase Inhibitors Derived from Cladosporin

scientific article published on 04 February 2019

Design of a high-throughput device for screening surface modification protocols

Development of a Cell Surface Display System in Chlamydomonas reinhardtii

scientific article published on 6 May 2021

Dimers of nostocarboline with potent antibacterial activity ⬇️

scientific article published on 13 August 2010

Direct Preparation of Pyrrolizidines Using Imines and Isonitriles

article published in 2015

Direct arginine modification in native peptides and application to chemical probe development

scientific article

Directed biosynthesis of phytotoxic alkaloids in the cyanobacterium Nostoc 78-12A.

scientific article published in March 2009

Enantioselective Synthesis of the Sporolide Quinone Acid Fragment

Enantioselective Total Syntheses and Absolute Configuration of JBIR-02 and Mer-A2026B

scientific article published on 18 January 2013

Enantioselective total synthesis of virosaine A and bubbialidine

scientific article published on 30 January 2013

Fluorescent labeling agents for quorum-sensing receptors (FLAQS) in live cells

scientific article published on 13 June 2013

Functionally Optimized Neuritogenic Farinosone C Analogs: SAR-Study and Investigations on Their Mode of Action

scientific article

Highly enantioselective inverse-electron-demand hetero-diels-alder reactions of alpha,beta-unsaturated aldehydes

scientific article

Investigating Biogenetic Hypotheses of the Securinega Alkaloids: Enantioselective Total Syntheses of Secu'amamine E/ent-Virosine A and Bubbialine

scientific article published on 17 January 2017

Investigating the Toxicity of the Aeruginosin Chlorosulfopeptides by Chemical Synthesis

scientific article

Isolation and Total Synthesis of Kirkamide, an Aminocyclitol from an Obligate Leaf Nodule Symbiont

Isolation and Total Synthesis of Kirkamide, an Aminocyclitol from an Obligate Leaf Nodule Symbiont. ⬇️

scientific article published in June 2015

Isolation and structure determination of two microcystins and sequence comparison of the McyABC adenylation domains in Planktothrix species ⬇️

scientific article published on 21 October 2008

Isolation of aerucyclamides C and D and structure revision of microcyclamide 7806A: heterocyclic ribosomal peptides from Microcystis aeruginosa PCC 7806 and their antiparasite evaluation

scientific article

Mechanistic studies on the tyrosinase-catalyzed formation of the anachelin chromophore

scientific article published in May 2005

Metal‐Free Regioselective Chloroazidation of Internal Alkynes

Microviridin 1777: A Toxic Chymotrypsin Inhibitor Discovered by a Metabologenomic Approach ⬇️

scientific article published on 28 January 2020

Mitigation of <i>Pseudomonas syringae</i> virulence by signal inactivation

scientific article published on 08 September 2021

Multiple toxin production in the cyanobacterium microcystis: isolation of the toxic protease inhibitor cyanopeptolin 1020. ⬇️

scientific article published in May 2010

Natural Product Hybrids

Neuritogenic surfaces using natural product analogs

scientific article

Nitrocatechols as Tractable Surface Release Systems

Nostocarboline: isolation and synthesis of a new cholinesterase inhibitor from Nostoc 78-12A.

scientific article published in December 2005

Occurrence of microcystin-producing cyanobacteria in Ugandan freshwater habitats ⬇️

scientific article

On-cell catalysis by surface engineering of live cells with an artificial metalloenzyme

article by Mathieu Szponarski et al published 20 November 2018 in Communications Chemistry

Out in the Green: Biologically Active Metabolites Produced by Cyanobacteria ⬇️

scientific article published on January 1, 2011

Peptide folding induces high and selective affinity of a linear and small beta-peptide to the human somatostatin receptor 4.

scientific article

Pleated Sheets and Turns ofβ-Peptides with Proteinogenic Side Chains

scientific article published on 01 June 1999

Poly(ethylene glycol) adlayers immobilized to metal oxide substrates through catechol derivatives: influence of assembly conditions on formation and stability

scientific article published in March 2010

Potent Algicides Based on the Cyanobacterial Alkaloid Nostocarboline

scientific article published on 01 February 2006

Potent and selective antiplasmodial activity of the cyanobacterial alkaloid nostocarboline and its dimers

scientific article published on 19 June 2008

Preparation and NMR Structure of the Cyclo-β-tripeptide [β3-HGlu]3 in Aqueous Solution: A New Class of Enterobactin-TypeC3-Symmetrical Ligands?, Preliminary Communication

Preparation of Antimalarial Endoperoxides by a Formal [2 + 2 + 2] Cycloaddition

scientific article published on 22 October 2015

Preparation of Fluorescent Microcystin Derivatives by Direct Arginine Labelling and Their Biological Evaluation

scientific article published on 12 June 2015

Preparation of Indolenines via Nucleophilic Aromatic Substitution

scientific article published on 05 March 2019

Prophage-triggered membrane vesicle formation through peptidoglycan damage in Bacillus subtilis

scientific article published on 7 September 2017

Protein-resistant surfaces through mild dopamine surface functionalization

scientific article

Pyrrolizidines for direct air capture and CO2 conversion

scientific article published on 01 January 2019

Reduce to the Maximum: Truncated Natural Products as Powerful Modulators of Biological Processes

Secondary Metabolites from Cyanobacteria: Complex Structures and Powerful Bioactivities

Securinega Alkaloids: Complex Structures, Potent Bioactivities, and Efficient Total Syntheses

Spatial isolation favours the divergence in microcystin net production by Microcystis in Ugandan freshwater lakes ⬇️

scientific article

Stable beta turns of tripeptides in water through cation-pi interactions

scientific article

Stereoselective Total Synthesis of (-)-Galantinic Acid

Strategies for the Asymmetric Total Synthesis of Natural Products: ‘‘Chiral Pool’’ versus Chiral Catalysts

Surface Assembly of Catechol-Functionalized Poly(l-lysine)-graft-poly(ethylene glycol) Copolymer on Titanium Exploiting Combined Electrostatically Driven Self-Organization and Biomimetic Strong Adhesion

scholarly article by Sina Saxer et al published 26 January 2010 in Macromolecules

Surface modifications based on the cyanobacterial siderophore anachelin: from structure to functional biomaterials design

scientific article published on 07 April 2009

Synthese von Aeruginosin-Chlorsulfopeptiden und Untersuchung ihrer Toxizität

Syntheses of Taiwaniaquinone F and Taiwaniaquinol A via an Unusual Remote C–H Functionalization

scientific article published on 05 March 2013

Synthesis and Biological Evaluation of a Cyclo-β-tetrapeptide as a Somatostatin Analogue

scientific article

Synthesis and Biological Evaluation of the Novel Growth Inhibitor Streptol Glucoside, Isolated from an Obligate Plant Symbiont

article

Synthesis and catalysis

scientific article published in January 2010

Synthesis and evaluation of the bis-nor-anachelin chromophore as potential cyanobacterial ligand

scientific article published in August 2005

Synthesis of Colibactin Pyrrolidono[3,4-d]pyridones via Regioselective C(sp3)-H Activation

scientific article published on 20 August 2020

Synthesis of Cyclo-β-tripeptides and Their Biologicalin vitro Evaluation as Antiproliferatives against the Growth of Human Cancer Cell Lines

Synthesis of Two Key Fragments of the Complex Polyhalogenated Marine Meroterpenoid Azamerone

scientific article published on 25 January 2019

Synthesis of maculalactone A and derivatives for environmental fate tracking studies

scientific article published in January 2015

Synthesis of withanolide A, biological evaluation of its neuritogenic properties, and studies on secretase inhibition

scientific article

Synthesis of β-Hexa- and β-Heptapeptides Containing Novel β2,3-Amino Acids with Two Serine or Two Cysteine Side Chains - CD- and NMR-Spectroscopic Evidence for 314-Helical Secondary Structures in Water

Synthetic Studies on the Sporolides: Exploration of the Enediyne Route

Synthetisch gewonnene Naturstofffragmente in der Wirkstoffentwicklung

Telomerase inhibitors from cyanobacteria: isolation and synthesis of sulfoquinovosyl diacylglycerols from Microcystis aeruguinosa PCC 7806.

scientific article

Temperature-Dependent NMR and CD Spectra ofβ-Peptides: On the Thermal Stability ofβ-Peptide Helices - Is the Folding Process ofβ-Peptides Non-cooperative?

The Cyclo-β-Tetrapeptide (β-HPhe-β-HThr-β-HLys-β-HTrp): Synthesis, NMR Structure in Methanol Solution, and Affinity for Human Somatostatin Receptors

The Furan Shuffling Hypothesis: A Biogenetic Proposal for Eremophilane Sesquiterpenoids

The Furan Shuffling Hypothesis: A Biogenetic Proposal for Eremophilane Sesquiterpenoids

scientific article published on 17 April 2019

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

scientific article published on June 2012

The beta-peptide hairpin in solution: conformational study of a beta-hexapeptide in methanol by NMR spectroscopy and MD simulation

scientific article published in March 2001

The cyanobacterial alkaloid nostocarboline: an inhibitor of acetylcholinesterase and trypsin

The cytotoxic styryl lactone goniothalamin is an inhibitor of nucleocytoplasmic transport

scientific article published on 24 March 2010

The fourth helical secondary structure of beta-peptides: the (P)-28-helix of a beta-hexapeptide consisting of (2R,3S)-3-amino-2-hydroxy acid residues

scientific article published in April 2003

The third orthogonal dynamic covalent bond

The toxicity and enzyme activity of a chlorine and sulfate containing aeruginosin isolated from a non-microcystin-producing Planktothrix strain ⬇️

scientific article published on October 2014

Total Synthesis and Biological Evaluation of the Glycosylated Macrocyclic Antibiotic Mangrolide A

Total Synthesis and Biological Evaluation of the Glycosylated Macrocyclic Antibiotic Mangrolide A

scientific article published on 18 July 2018

Total Synthesis and Neuritotrophic Activity of Farinosone C and Derivatives

scientific article published on 01 August 2009

Total Synthesis and Structural Revision of Aeruginosin KT608A.

scientific article published on 11 July 2017

Total Synthesis and Structural Revision of Mangrolide D

scientific article published on 23 April 2019

Total Synthesis of Anachelin H

scientific article published on 01 December 2004

Total Synthesis of Complex Cyanobacterial Alkaloids without Using Protecting Groups

scientific article published on 01 January 2007

Total Synthesis of Cyrneine A

scientific article published on 16 March 2012

Total Synthesis of Gelsemiol

scientific article published on 10 January 2013

Total Synthesis of Tiacumicin A. Total Synthesis, Relay Synthesis, and Degradation Studies of Fidaxomicin (Tiacumicin B, Lipiarmycin A3)

scientific article published on 12 April 2018

Total Synthesis of the Glycosylated Macrolide Antibiotic Fidaxomicin

scientific article published on 30 June 2015

Total Synthesis of the Marine Alkaloid Palau’amine

scientific article published on 01 April 2010

Total Synthesis of the Sesquiterpenoid Periconianone A Based on a Postulated Biogenesis ⬇️

scientific article

Total synthesis of the protected aglycon of fidaxomicin (tiacumicin B, lipiarmycin A3).

scientific article published on 27 November 2014

Total synthesis, configuration, and biological evaluation of anguinomycin C.

scientific article

Truncated militarinone fragments identified by total chemical synthesis induce neurite outgrowth

Withanolide A: synthesis and structural requirements for neurite outgrowth

β-Thiopeptides: Synthesis, NMR Solution Structure, CD Spectra, and Photochemistry

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